{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T05:32:44Z","timestamp":1785735164751,"version":"3.56.0"},"reference-count":49,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100001422","name":"American Society of Hematology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001422","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","clinical-lymphoma-myeloma-leukemia.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Lymphoma Myeloma and Leukemia"],"published-print":{"date-parts":[[2022,10]]},"DOI":"10.1016\/j.clml.2022.05.008","type":"journal-article","created":{"date-parts":[[2022,5,29]],"date-time":"2022-05-29T13:35:43Z","timestamp":1653831343000},"page":"726-734","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"title":["Prognostic Impact of Adiposity in Hematological Malignancies: A Systematic Review and Meta-analysis"],"prefix":"10.1016","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9329-6044","authenticated-orcid":false,"given":"Gabriel F.P.","family":"Aleixo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Sheu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saeid","family":"Mirzai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Navneet S.","family":"Majhail","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.clml.2022.05.008_bib0001","doi-asserted-by":"crossref","first-page":"1505","DOI":"10.1038\/bjc.2011.68","article-title":"Differential trends in the rising incidence of endometrial cancer by type: data from a UK population-based registry from 1994 to 2006","volume":"104","author":"Evans","year":"2011","journal-title":"Br J Cancer"},{"issue":"12","key":"10.1016\/j.clml.2022.05.008_bib0002","doi-asserted-by":"crossref","first-page":"2947","DOI":"10.1002\/ijc.24913","article-title":"Prospective study of body mass index, physical activity and thyroid cancer","volume":"126","author":"Leitzmann","year":"2010","journal-title":"Int J Cancer"},{"issue":"3","key":"10.1016\/j.clml.2022.05.008_bib0003","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/j.ejca.2007.12.009","article-title":"A prospective study of BMI and risk of oesophageal and gastric adenocarcinoma","volume":"44","author":"Abnet","year":"2008","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.clml.2022.05.008_bib0004","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.canep.2016.02.010","article-title":"Associations of body mass index with cancer incidence among populations, genders, and menopausal status: a systematic review and meta-analysis","volume":"42","author":"Wang","year":"2016","journal-title":"Cancer Epidemiol"},{"issue":"6","key":"10.1016\/j.clml.2022.05.008_bib0005","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1038\/ejcn.2016.225","article-title":"Effect of body mass index on overall survival of patients with allogeneic hematopoietic stem cell transplantation","volume":"71","author":"Yang","year":"2017","journal-title":"Eur J Clin Nutr"},{"key":"10.1016\/j.clml.2022.05.008_bib0006","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1186\/1471-2407-14-728","article-title":"Survival in overweight patients with advanced pancreatic carcinoma: a multicentre cohort study","volume":"14","author":"Kasenda","year":"2014","journal-title":"BMC Cancer"},{"issue":"10","key":"10.1016\/j.clml.2022.05.008_bib0007","doi-asserted-by":"crossref","first-page":"2394","DOI":"10.1002\/ijc.24907","article-title":"Cigarette smoking, environmental tobacco smoke exposure and pancreatic cancer risk in the European Prospective Investigation into Cancer and Nutrition","volume":"126","author":"Vrieling","year":"2010","journal-title":"Int J Cancer"},{"issue":"5","key":"10.1016\/j.clml.2022.05.008_bib0008","first-page":"817","article-title":"Systematic review of prognostic roles of body mass index for patients undergoing lung cancer surgery: does the 'obesity paradox' really exist?","volume":"51","author":"Li","year":"2017","journal-title":"Eur J Cardiothorac Surg"},{"issue":"9","key":"10.1016\/j.clml.2022.05.008_bib0009","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1007\/s11912-016-0539-4","article-title":"The obesity paradox in cancer: a review","volume":"18","author":"Lennon","year":"2016","journal-title":"Curr Oncol Rep"},{"issue":"4","key":"10.1016\/j.clml.2022.05.008_bib0010","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1016\/j.urology.2006.05.024","article-title":"Greater body mass index is associated with better pathologic features and improved outcome among patients treated surgically for clear cell renal cell carcinoma","volume":"68","author":"Parker","year":"2006","journal-title":"Urology"},{"key":"10.1016\/j.clml.2022.05.008_bib0011","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.ejca.2015.12.030","article-title":"Prognostic value of sarcopenia in adults with solid tumours: a meta-analysis and systematic review","volume":"57","author":"Shachar","year":"2016","journal-title":"Eur J Cancer"},{"issue":"24","key":"10.1016\/j.clml.2022.05.008_bib0012","doi-asserted-by":"crossref","first-page":"1862","DOI":"10.1093\/jnci\/djt310","article-title":"An epidemiologic and genomic investigation into the obesity paradox in renal cell carcinoma","volume":"105","author":"Hakimi","year":"2013","journal-title":"J Natl Cancer Inst"},{"issue":"10","key":"10.1016\/j.clml.2022.05.008_bib0013","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1007\/s10552-014-0435-x","article-title":"Postdiagnosis body mass index and risk of mortality in colorectal cancer survivors: a prospective study and meta-analysis","volume":"25","author":"Schlesinger","year":"2014","journal-title":"Cancer Causes Control"},{"issue":"2","key":"10.1016\/j.clml.2022.05.008_bib0014","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/j.jss.2015.05.059","article-title":"Differential impact of obesity and diabetes mellitus on survival after liver resection for colorectal cancer metastases","volume":"199","author":"Amptoulach","year":"2015","journal-title":"J Surg Res"},{"issue":"8","key":"10.1016\/j.clml.2022.05.008_bib0015","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1002\/ajh.23462","article-title":"Association between baseline body mass index and overall survival among patients over age 60 with acute myeloid leukemia","volume":"88","author":"Brunner","year":"2013","journal-title":"Am J Hematol"},{"issue":"5","key":"10.1016\/j.clml.2022.05.008_bib0016","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.bbmt.2005.12.033","article-title":"Effect of body mass index on mortality of patients with lymphoma undergoing autologous hematopoietic cell transplantation","volume":"12","author":"Navarro","year":"2006","journal-title":"Biol Blood Marrow Transplant"},{"issue":"6","key":"10.1016\/j.clml.2022.05.008_bib0017","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1016\/j.jamcollsurg.2013.01.007","article-title":"Quantitative measures of visceral adiposity and body mass index in predicting rectal cancer outcomes after neoadjuvant chemoradiation","volume":"216","author":"Clark","year":"2013","journal-title":"J Am Coll Surg"},{"issue":"2","key":"10.1016\/j.clml.2022.05.008_bib0018","doi-asserted-by":"crossref","first-page":"e12611","DOI":"10.1111\/ecc.12611","article-title":"Visceral adiposity and cancer survival: a review of imaging studies","volume":"27","author":"Xiao","year":"2018","journal-title":"Eur J Cancer Care (Engl)"},{"issue":"1","key":"10.1016\/j.clml.2022.05.008_bib0019","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1111\/j.1467-789X.2009.00623.x","article-title":"Subcutaneous and visceral adipose tissue: structural and functional differences","volume":"11","author":"Ibrahim","year":"2010","journal-title":"Obes Rev"},{"key":"10.1016\/j.clml.2022.05.008_bib0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.critrevonc.2019.102839","article-title":"Myosteatosis and prognosis in cancer: systematic review and meta-analysis","volume":"145","author":"Aleixo","year":"2020","journal-title":"Crit Rev Oncol Hematol"},{"issue":"4","key":"10.1016\/j.clml.2022.05.008_bib0021","doi-asserted-by":"crossref","first-page":"264","DOI":"10.7326\/0003-4819-151-4-200908180-00135","article-title":"Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement","volume":"151","author":"Moher","year":"2009","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.clml.2022.05.008_bib0022","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/1472-6947-7-16","article-title":"Utilization of the PICO framework to improve searching PubMed for clinical questions","volume":"7","author":"Schardt","year":"2007","journal-title":"BMC Med Inform Decis Mak"},{"issue":"7414","key":"10.1016\/j.clml.2022.05.008_bib0023","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","article-title":"Measuring inconsistency in meta-analyses","volume":"327","author":"Higgins","year":"2003","journal-title":"BMJ"},{"key":"10.1016\/j.clml.2022.05.008_bib0024","doi-asserted-by":"crossref","first-page":"d5928","DOI":"10.1136\/bmj.d5928","article-title":"The Cochrane Collaboration's tool for assessing risk of bias in randomised trials","volume":"343","author":"Higgins","year":"2011","journal-title":"BMJ"},{"key":"10.1016\/j.clml.2022.05.008_bib0025","doi-asserted-by":"crossref","first-page":"359","DOI":"10.2147\/CLEP.S66677","article-title":"Quality assessment of observational studies in a drug-safety systematic review, comparison of two tools: the Newcastle-Ottawa Scale and the RTI item bank","volume":"6","author":"Margulis","year":"2014","journal-title":"Clin Epidemiol"},{"issue":"12","key":"10.1016\/j.clml.2022.05.008_bib0026","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1016\/j.ijsu.2014.07.013","article-title":"The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement: guidelines for reporting observational studies","volume":"12","author":"von Elm","year":"2014","journal-title":"Int J Surg"},{"issue":"8","key":"10.1016\/j.clml.2022.05.008_bib0027","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/j.clml.2016.04.010","article-title":"Prognostic effect of low subcutaneous adipose tissue on survival outcome in patients with multiple myeloma","volume":"16","author":"Takeoka","year":"2016","journal-title":"Clin Lymphoma Myeloma Leuk"},{"issue":"3","key":"10.1016\/j.clml.2022.05.008_bib0028","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1007\/s00277-015-2571-0","article-title":"Visceral adipose tissue is prognostic for survival of diffuse large B cell lymphoma treated with frontline R-CHOP","volume":"95","author":"Shin","year":"2016","journal-title":"Ann Hematol"},{"issue":"2","key":"10.1016\/j.clml.2022.05.008_bib0029","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1007\/s00277-018-3508-1","article-title":"Prognostic impact of skeletal muscle assessed by computed tomography in patients with acute myeloid leukemia","volume":"98","author":"Nakamura","year":"2019","journal-title":"Ann Hematol"},{"key":"10.1016\/j.clml.2022.05.008_bib0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.nut.2021.111141","article-title":"Adipose tissue radiodensity: a new prognostic biomarker in people with multiple myeloma","volume":"86","author":"da Cunha","year":"2021","journal-title":"Nutrition"},{"issue":"1","key":"10.1016\/j.clml.2022.05.008_bib0031","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1111\/ejh.12285","article-title":"Prognostic impact of fat tissue loss and cachexia assessed by computed tomography scan in elderly patients with diffuse large B-cell lymphoma treated with immunochemotherapy","volume":"93","author":"Camus","year":"2014","journal-title":"Eur J Haematol"},{"issue":"1","key":"10.1016\/j.clml.2022.05.008_bib0032","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1111\/bjh.15889","article-title":"Evaluation of the impact of cachexia on clinical outcomes in aggressive lymphoma","volume":"186","author":"Burkart","year":"2019","journal-title":"Br J Haematol"},{"issue":"1","key":"10.1016\/j.clml.2022.05.008_bib0033","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1007\/s12185-021-03122-w","article-title":"Prediction of clinical outcomes through assessment of sarcopenia and adipopenia using computed tomography in adult patients with acute myeloid leukemia","volume":"114","author":"Jung","year":"2021","journal-title":"Int J Hematol"},{"issue":"6","key":"10.1016\/j.clml.2022.05.008_bib0034","doi-asserted-by":"crossref","first-page":"3299","DOI":"10.4049\/jimmunol.1003613","article-title":"Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets","volume":"186","author":"Michalek","year":"2011","journal-title":"J Immunol"},{"issue":"11","key":"10.1016\/j.clml.2022.05.008_bib0035","doi-asserted-by":"crossref","first-page":"2582","DOI":"10.1634\/stemcells.2006-0228","article-title":"Adipose tissue-derived mesenchymal stem cells have in vivo immunosuppressive properties applicable for the control of the graft-versus-host disease","volume":"24","author":"Yanez","year":"2006","journal-title":"Stem Cells"},{"issue":"7","key":"10.1016\/j.clml.2022.05.008_bib0036","doi-asserted-by":"crossref","first-page":"1831","DOI":"10.1002\/stem.1676","article-title":"Human adipose-derived stromal\/stem cells protect against STZ-induced hyperglycemia: analysis of hASC-derived paracrine effectors","volume":"32","author":"Kono","year":"2014","journal-title":"Stem Cells"},{"issue":"1009","key":"10.1016\/j.clml.2022.05.008_bib0037","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1259\/bjr\/38447238","article-title":"The clinical importance of visceral adiposity: a critical review of methods for visceral adipose tissue analysis","volume":"85","author":"Shuster","year":"2012","journal-title":"Br J Radiol"},{"issue":"1","key":"10.1016\/j.clml.2022.05.008_bib0038","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1159\/000318988","article-title":"Influence of visceral obesity on oncologic outcome in patients with renal cell carcinoma","volume":"85","author":"Naya","year":"2010","journal-title":"Urol Int"},{"issue":"14","key":"10.1016\/j.clml.2022.05.008_bib0039","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1172\/jci.insight.121221","article-title":"Infante RE. Cachexia-associated adipose loss induced by tumor-secreted leukemia inhibitory factor is counterbalanced by decreased leptin","volume":"3","author":"Arora","year":"2018","journal-title":"JCI Insight"},{"issue":"6","key":"10.1016\/j.clml.2022.05.008_bib0040","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.clml.2021.01.008","article-title":"Overweight\/obesity and monoclonal gammopathy of undetermined significance","volume":"21","author":"Georgakopoulou","year":"2021","journal-title":"Clin Lymphoma Myeloma Leuk"},{"issue":"9","key":"10.1016\/j.clml.2022.05.008_bib0041","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1007\/s00256-016-2425-4","article-title":"Abdominal adipose tissue in MGUS and multiple myeloma","volume":"45","author":"Veld","year":"2016","journal-title":"Skeletal Radiol"},{"issue":"40","key":"10.1016\/j.clml.2022.05.008_bib0042","doi-asserted-by":"crossref","first-page":"68460","DOI":"10.18632\/oncotarget.19536","article-title":"Body fat composition as predictive factor for treatment response in patients with newly diagnosed multiple myeloma - subgroup analysis of the prospective GMMG MM5 trial","volume":"8","author":"GroDelta","year":"2017","journal-title":"Oncotarget"},{"issue":"11","key":"10.1016\/j.clml.2022.05.008_bib0043","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1016\/j.acra.2013.08.012","article-title":"Accurate detection of metabolically active \"brown\" and \"white\" adipose tissues with computed tomography","volume":"20","author":"Ahmadi","year":"2013","journal-title":"Acad Radiol"},{"issue":"3","key":"10.1016\/j.clml.2022.05.008_bib0044","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/j.cmet.2014.06.011","article-title":"A switch from white to brown fat increases energy expenditure in cancer-associated cachexia","volume":"20","author":"Petruzzelli","year":"2014","journal-title":"Cell Metab"},{"key":"10.1016\/j.clml.2022.05.008_bib0045","doi-asserted-by":"crossref","first-page":"1917","DOI":"10.1093\/ajcn\/nqab285","article-title":"Abdominal adipose tissue radiodensity is associated with survival after colorectal cancer","author":"Feliciano","year":"2021","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.clml.2022.05.008_bib0046","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1146\/annurev.nutr.26.061505.111151","article-title":"Cancer-associated cachexia and underlying biological mechanisms","volume":"26","author":"Baracos","year":"2006","journal-title":"Annu Rev Nutr"},{"issue":"2","key":"10.1016\/j.clml.2022.05.008_bib0047","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.currproblcancer.2011.01.001","article-title":"Nutritional interventions for cancer-induced cachexia","volume":"35","author":"Gullett","year":"2011","journal-title":"Curr Probl Cancer"},{"issue":"4","key":"10.1016\/j.clml.2022.05.008_bib0048","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1007\/s00394-009-0082-2","article-title":"Glutamine as indispensable nutrient in oncology: experimental and clinical evidence","volume":"49","author":"Kuhn","year":"2010","journal-title":"Eur J Nutr"},{"issue":"8","key":"10.1016\/j.clml.2022.05.008_bib0049","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1016\/j.ejca.2008.02.033","article-title":"Cancer cachexia: developing multimodal therapy for a multidimensional problem","volume":"44","author":"Fearon","year":"2008","journal-title":"Eur J Cancer"}],"container-title":["Clinical Lymphoma Myeloma and Leukemia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2152265022001690?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2152265022001690?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,10,25]],"date-time":"2024-10-25T11:47:04Z","timestamp":1729856824000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2152265022001690"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":49,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["S2152265022001690"],"URL":"https:\/\/doi.org\/10.1016\/j.clml.2022.05.008","relation":{},"ISSN":["2152-2650"],"issn-type":[{"value":"2152-2650","type":"print"}],"subject":[],"published":{"date-parts":[[2022,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prognostic Impact of Adiposity in Hematological Malignancies: A Systematic Review and Meta-analysis","name":"articletitle","label":"Article Title"},{"value":"Clinical Lymphoma Myeloma and Leukemia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clml.2022.05.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}