{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T21:06:37Z","timestamp":1787951197484,"version":"build-2784847793"},"reference-count":21,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","clinical-lymphoma-myeloma-leukemia.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Lymphoma Myeloma and Leukemia"],"published-print":{"date-parts":[[2023,2]]},"DOI":"10.1016\/j.clml.2022.10.011","type":"journal-article","created":{"date-parts":[[2022,11,4]],"date-time":"2022-11-04T04:19:28Z","timestamp":1667535568000},"page":"123-126","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["T-Cell Monoclonality in the Blood and the Skin Correlates With Poor Response to Treatment in Mycosis Fungoides"],"prefix":"10.1016","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1206-1057","authenticated-orcid":false,"given":"Shamir","family":"Geller","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shira F.","family":"Tel-Dan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irit","family":"Solar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eli","family":"Sprecher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilan","family":"Goldberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.clml.2022.10.011_bib0001","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41572-021-00296-9","article-title":"Cutaneous T cell lymphoma","volume":"7","author":"Dummer","year":"2021","journal-title":"Nat Rev Dis Primer"},{"key":"10.1016\/j.clml.2022.10.011_bib0002","doi-asserted-by":"crossref","first-page":"320","DOI":"10.2353\/jmoldx.2010.090123","article-title":"Combined use of PCR-based TCRG and TCRB clonality tests on paraffin-embedded skin tissue in the differential diagnosis of mycosis fungoides and inflammatory dermatoses","volume":"12","author":"Zhang","year":"2010","journal-title":"J Mol Diagn JMD"},{"key":"10.1016\/j.clml.2022.10.011_bib0003","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1016\/j.jaad.2020.05.110","article-title":"Evaluation of the polymerase chain reaction-based T-cell receptor \u03b2 clonality test in the diagnosis of early mycosis fungoides","volume":"83","author":"Schachter","year":"2020","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.clml.2022.10.011_bib0004","doi-asserted-by":"crossref","first-page":"522","DOI":"10.6004\/jnccn.2020.0022","article-title":"NCCN guidelines insights: primary cutaneous lymphomas, version 2.2020","volume":"18","author":"Mehta-Shah","year":"2020","journal-title":"J Natl Compr Cancer Netw JNCCN"},{"key":"10.1016\/j.clml.2022.10.011_bib0005","doi-asserted-by":"crossref","first-page":"4730","DOI":"10.1200\/JCO.2009.27.7665","article-title":"Survival outcomes and prognostic factors in mycosis fungoides\/S\u00e9zary syndrome: validation of the revised international society for cutaneous lymphomas\/European organization for research and treatment of cancer staging proposal","volume":"28","author":"Agar","year":"2010","journal-title":"J Clin Oncol Off J Am Soc Clin Oncol"},{"key":"10.1016\/j.clml.2022.10.011_bib0006","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1111\/bjd.14017","article-title":"Frequency and prognostic value of cutaneous molecular residual disease in mycosis fungoides: a prospective multicentre trial of the cutaneous lymphoma french study group","volume":"173","author":"Hurabielle","year":"2015","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.clml.2022.10.011_bib0007","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1111\/bjd.13939","article-title":"Stage I mycosis fungoides: frequent association with a favourable prognosis but disease progression and disease-specific mortality may occur","volume":"173","author":"Wernham","year":"2015","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.clml.2022.10.011_bib0008","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1111\/bjd.15000","article-title":"Prognostic indicators for mycosis fungoides in a Greek population","volume":"176","author":"Nikolaou","year":"2017","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.clml.2022.10.011_bib0009","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1182\/blood-2018-11-881268","article-title":"The 2018 update of the WHO-EORTC classification for primary cutaneous lymphomas","volume":"133","author":"Willemze","year":"2019","journal-title":"Blood"},{"key":"10.1016\/j.clml.2022.10.011_bib0010","doi-asserted-by":"crossref","first-page":"2257","DOI":"10.1038\/sj.leu.2403202","article-title":"Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: report of the BIOMED-2 Concerted Action BMH4-CT98-3936","volume":"17","author":"van Dongen","year":"2003","journal-title":"Leukemia"},{"key":"10.1016\/j.clml.2022.10.011_bib0011","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/S1525-1578(10)60580-6","article-title":"BIOMED-2 multiplex immunoglobulin\/T-cell receptor polymerase chain reaction protocols can reliably replace Southern blot analysis in routine clonality diagnostics","volume":"7","author":"Sandberg","year":"2005","journal-title":"J Mol Diagn JMD"},{"key":"10.1016\/j.clml.2022.10.011_bib0012","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1097\/PDM.0b013e3181b2a1b7","article-title":"Evaluation of T-cell clonality in archival skin biopsy samples of cutaneous T-cell lymphomas using the biomed-2 PCR protocol","volume":"19","author":"Lukowsky","year":"2010","journal-title":"Diagn Mol Pathol Am J Surg Pathol Part B"},{"key":"10.1016\/j.clml.2022.10.011_bib0013","doi-asserted-by":"crossref","first-page":"2598","DOI":"10.1200\/JCO.2010.32.0630","volume":"29","author":"Olsen","year":"2011","journal-title":"J Clin Oncol Off J Am Soc Clin Oncol"},{"key":"10.1016\/j.clml.2022.10.011_bib0014","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1182\/blood-2007-03-055749","volume":"110","author":"Olsen","year":"2007","journal-title":"Blood"},{"key":"10.1016\/j.clml.2022.10.011_bib0015","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1182\/blood-2004-06-2220","article-title":"Early TCR-beta and TCR-gamma PCR detection of T-cell clonality indicates minimal tumor disease in lymph nodes of cutaneous T-cell lymphoma: diagnostic and prognostic implications","volume":"105","author":"Assaf","year":"2005","journal-title":"Blood"},{"key":"10.1016\/j.clml.2022.10.011_bib0016","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1046\/j.1523-1747.2000.00830.x","article-title":"Detection of a peripheral blood T cell clone is an independent prognostic marker in mycosis fungoides","volume":"114","author":"Fraser-Andrews","year":"2000","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.clml.2022.10.011_bib0017","doi-asserted-by":"crossref","first-page":"3766","DOI":"10.1200\/JCO.2015.61.7142","article-title":"Cutaneous lymphoma international consortium study of outcome in advanced stages of mycosis Fungoides and s\u00e9zary syndrome: effect of specific prognostic markers on survival and development of a prognostic model","volume":"33","author":"Scarisbrick","year":"2015","journal-title":"J Clin Oncol Off J Am Soc Clin Oncol"},{"key":"10.1016\/j.clml.2022.10.011_bib0018","doi-asserted-by":"crossref","first-page":"269rv1","DOI":"10.1126\/scitranslmed.3010641","article-title":"Resident memory T cells in human health and disease","volume":"7","author":"Clark","year":"2015","journal-title":"Sci Transl Med"},{"key":"10.1016\/j.clml.2022.10.011_bib0019","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1111\/bjd.17258","article-title":"The PROCLIPI international registry of early-stage mycosis fungoides identifies substantial diagnostic delay in most patients","volume":"181","author":"Scarisbrick","year":"2019","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.clml.2022.10.011_bib0020","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1136\/jclinpath-2018-205004","article-title":"Role of high-throughput sequencing in the diagnosis of cutaneous T-cell lymphoma","volume":"71","author":"Rea","year":"2018","journal-title":"J Clin Pathol"},{"key":"10.1016\/j.clml.2022.10.011_bib0021","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.jaad.2015.04.030","article-title":"T-cell clonality assessment by next-generation sequencing improves detection sensitivity in mycosis fungoides","volume":"73","author":"Sufficool","year":"2015","journal-title":"J Am Acad Dermatol"}],"container-title":["Clinical Lymphoma Myeloma and Leukemia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2152265022017177?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2152265022017177?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T00:41:26Z","timestamp":1761871286000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2152265022017177"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2]]},"references-count":21,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,2]]}},"alternative-id":["S2152265022017177"],"URL":"https:\/\/doi.org\/10.1016\/j.clml.2022.10.011","relation":{},"ISSN":["2152-2650"],"issn-type":[{"value":"2152-2650","type":"print"}],"subject":[],"published":{"date-parts":[[2023,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"T-Cell Monoclonality in the Blood and the Skin Correlates With Poor Response to Treatment in Mycosis Fungoides","name":"articletitle","label":"Article Title"},{"value":"Clinical Lymphoma Myeloma and Leukemia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clml.2022.10.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}