{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T22:05:25Z","timestamp":1787954725103,"version":"build-2784847793"},"reference-count":19,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003500","name":"Universita degli Studi di Padova","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003500","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","clinicalnutritionespen.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Nutrition ESPEN"],"published-print":{"date-parts":[[2021,6]]},"DOI":"10.1016\/j.clnesp.2021.03.003","type":"journal-article","created":{"date-parts":[[2021,3,18]],"date-time":"2021-03-18T20:20:36Z","timestamp":1616098836000},"page":"471-477","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"special_numbering":"C","title":["Association of body surface area with fat mass, free fat mass and total weight in healthy individuals, and implications for the dosage of cytotoxic drugs"],"prefix":"10.1016","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8803-0524","authenticated-orcid":false,"given":"Bruno Micael","family":"Zanforlini","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agnese","family":"Alessi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Pontarin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"De Rui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Zoccarato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniele Michele","family":"Seccia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caterina","family":"Trevisan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonella","family":"Brunello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Umberto","family":"Basso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enzo","family":"Manzato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Sergi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"13","key":"10.1016\/j.clnesp.2021.03.003_bib1","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1200\/JCO.2011.39.9436","article-title":"Appropriate chemotherapy dosing for obese adult patients with cancer: American Society of Clinical Oncology clinical practice guideline","volume":"30","author":"Griggs","year":"2012","journal-title":"J\u00a0Clin Oncol"},{"issue":"2","key":"10.1016\/j.clnesp.2021.03.003_bib2","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1023\/A:1010639201787","article-title":"Body surface area as a determinant of pharmacokinetics and drug dosing","volume":"19","author":"Sawyer","year":"2001","journal-title":"Invest N Drugs"},{"issue":"4","key":"10.1016\/j.clnesp.2021.03.003_bib3","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1038\/clpt.2014.7","article-title":"The scientific basis of body surface area-based dosing","volume":"95","author":"Chatelut","year":"2014","journal-title":"Clin Pharmacol Ther"},{"issue":"5","key":"10.1016\/j.clnesp.2021.03.003_bib4","first-page":"303","article-title":"A\u00a0formula to estimate the approximate surface area if height and weight be known","volume":"5","author":"Du Bois","year":"1916","journal-title":"Nutrition"},{"issue":"8","key":"10.1016\/j.clnesp.2021.03.003_bib5","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1007\/s12603-015-0653-2","article-title":"Body composition and anti-neoplastic treatment in adult and older subjects - a systematic review","volume":"20","author":"G\u00e9rard","year":"2016","journal-title":"J\u00a0Nutr Health Aging"},{"issue":"1","key":"10.1016\/j.clnesp.2021.03.003_bib6","first-page":"259","article-title":"Body composition variations in ageing","volume":"35","author":"Buffa","year":"2011","journal-title":"Coll Antropol"},{"key":"10.1016\/j.clnesp.2021.03.003_bib7","article-title":"Sarcopenia: revised European consensus on definition and diagnosis","author":"Cruz-Jentoft","year":"2018","journal-title":"Age Ageing"},{"issue":"4","key":"10.1016\/j.clnesp.2021.03.003_bib8","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1093\/ageing\/afq034","article-title":"Sarcopenia: European consensus on definition and diagnosis","volume":"39","author":"Cruz-Jentoft","year":"2010","journal-title":"Age Ageing"},{"issue":"2","key":"10.1016\/j.clnesp.2021.03.003_bib9","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1080\/03602530902722679","article-title":"Pharmacokinetics and drug metabolism in the elderly","volume":"41","author":"Klotz","year":"2009","journal-title":"Drug Metab Rev"},{"issue":"3","key":"10.1016\/j.clnesp.2021.03.003_bib10","doi-asserted-by":"crossref","first-page":"974","DOI":"10.3945\/ajcn.113.080168","article-title":"Effect of oral magnesium supplementation on physical performance in healthy elderly women involved in a weekly exercise program: a randomized controlled trial","volume":"100","author":"Veronese","year":"2014","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.clnesp.2021.03.003_bib11","series-title":"Fisher's r-to-Z transformation calculator to compare two independent samples [Computer software]","author":"Weiss","year":"2011"},{"key":"10.1016\/j.clnesp.2021.03.003_bib12","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1037\/0033-2909.87.2.245","article-title":"Tests for comparing elements of a correlation matrix","volume":"87","author":"Steiger","year":"1980","journal-title":"Psychol Bull"},{"issue":"5","key":"10.1016\/j.clnesp.2021.03.003_bib13","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.1152\/japplphysiol.00174.2018","article-title":"Cardiovascular and skeletal muscle health with lifelong exercise","volume":"125","author":"Gries","year":"2018","journal-title":"J\u00a0Appl Physiol"},{"issue":"5","key":"10.1016\/j.clnesp.2021.03.003_bib14","doi-asserted-by":"crossref","first-page":"419","DOI":"10.3109\/13697137.2012.707385","article-title":"Understanding weight gain at menopause","volume":"15","author":"Davis","year":"2012","journal-title":"Climacteric"},{"issue":"2","key":"10.1016\/j.clnesp.2021.03.003_bib15","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1046\/j.1365-2125.2002.01598.x","article-title":"Relationships between body composition parameters and fluorouracil pharmacokinetics","volume":"54","author":"Gusella","year":"2002","journal-title":"Br J Clin Pharmacol"},{"key":"10.1016\/j.clnesp.2021.03.003_bib16","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.pharmthera.2018.12.003","article-title":"Body composition and sarcopenia: the next-generation of personalized oncology and pharmacology?","volume":"196","author":"Hilmi","year":"2019","journal-title":"Pharmacol Ther"},{"issue":"7","key":"10.1016\/j.clnesp.2021.03.003_bib17","doi-asserted-by":"crossref","first-page":"2297","DOI":"10.1200\/JCO.1998.16.7.2297","article-title":"Body-surface area as a basis for dosing of anticancer agents: science, myth, or habit?","volume":"16","author":"Ratain","year":"1998","journal-title":"J\u00a0Clin Oncol"},{"issue":"7","key":"10.1016\/j.clnesp.2021.03.003_bib18","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/S1470-2045(08)70153-0","article-title":"Prevalence and clinical implications of sarcopenic obesity in patients with solid tumours of the respiratory and gastrointestinal tracts: a population-based study","volume":"9","author":"Prado","year":"2008","journal-title":"Lancet Oncol"},{"issue":"14","key":"10.1016\/j.clnesp.2021.03.003_bib19","doi-asserted-by":"crossref","first-page":"3537","DOI":"10.1158\/1078-0432.CCR-16-2266","article-title":"Body composition as a predictor of toxicity in patients receiving anthracycline and taxane-based chemotherapy for early-stage breast cancer","volume":"23","author":"Shachar","year":"2017","journal-title":"Clin Canc Res"}],"container-title":["Clinical Nutrition ESPEN"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405457721001029?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405457721001029?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T07:01:25Z","timestamp":1762498885000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2405457721001029"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6]]},"references-count":19,"alternative-id":["S2405457721001029"],"URL":"https:\/\/doi.org\/10.1016\/j.clnesp.2021.03.003","relation":{},"ISSN":["2405-4577"],"issn-type":[{"value":"2405-4577","type":"print"}],"subject":[],"published":{"date-parts":[[2021,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association of body surface area with fat mass, free fat mass and total weight in healthy individuals, and implications for the dosage of cytotoxic drugs","name":"articletitle","label":"Article Title"},{"value":"Clinical Nutrition ESPEN","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clnesp.2021.03.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}