{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T06:14:48Z","timestamp":1783145688327,"version":"3.54.6"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,8,20]],"date-time":"2021-08-20T00:00:00Z","timestamp":1629417600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004702","name":"Baxter International","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004702","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008984","name":"International Anesthesia Research Society","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008984","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100016040","name":"Takeda Canada","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016040","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","clinicalnutritionespen.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Nutrition ESPEN"],"published-print":{"date-parts":[[2021,10]]},"DOI":"10.1016\/j.clnesp.2021.07.021","type":"journal-article","created":{"date-parts":[[2021,8,2]],"date-time":"2021-08-02T21:05:39Z","timestamp":1627938339000},"page":"341-350","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":49,"special_numbering":"C","title":["Prolonged progressive hypermetabolism during COVID-19 hospitalization undetected by common predictive energy equations"],"prefix":"10.1016","volume":"45","author":[{"given":"Laura E.","family":"Niederer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hilary","family":"Miller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krista L.","family":"Haines","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeroen","family":"Molinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3859-679X","authenticated-orcid":false,"given":"John","family":"Whittle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5989-3961","authenticated-orcid":false,"given":"David B.","family":"MacLeod","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen A.","family":"McClave","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul E.","family":"Wischmeyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.clnesp.2021.07.021_bib1","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.clnesp.2021.03.019","article-title":"Energy expenditure and feeding practices and tolerance during the acute and late phase of critically ill COVID-19 patients","volume":"43","author":"Lakenman","year":"2021","journal-title":"Clinical Nutrition ESPEN"},{"issue":"1","key":"10.1016\/j.clnesp.2021.07.021_bib2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13054-020-03286-7","article-title":"Persistent hypermetabolism and longitudinal energy expenditure in critically ill patients with COVID-19","volume":"24","author":"Whittle","year":"2020","journal-title":"Crit Care"},{"issue":"7","key":"10.1016\/j.clnesp.2021.07.021_bib3","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1002\/jpen.1948","article-title":"Hypermetabolism and coronavirus disease 2019","volume":"44","author":"Yu","year":"2020","journal-title":"J\u00a0Parenter Enteral Nutr"},{"issue":"7","key":"10.1016\/j.clnesp.2021.07.021_bib4","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1002\/jpen.1930","article-title":"Nutrition therapy in critically ill patients with coronavirus disease 2019","volume":"44","author":"Martindale","year":"2020","journal-title":"J\u00a0Parenter Enteral Nutr"},{"issue":"2","key":"10.1016\/j.clnesp.2021.07.021_bib5","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1177\/0148607115621863","article-title":"Guidelines for the provision and assessment of nutrition support therapy in the adult critically ill patient: Society of Critical Care Medicine (SCCM) and American Society for Parenteral and Enteral Nutrition (ASPEN)","volume":"40","author":"McClave","year":"2016","journal-title":"JPEN - J Parenter Enter Nutr"},{"issue":"1","key":"10.1016\/j.clnesp.2021.07.021_bib6","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.clnu.2018.08.037","article-title":"ESPEN guideline on clinical nutrition in the intensive care unit","volume":"38","author":"Singer","year":"2019","journal-title":"Clin Nutr"},{"key":"10.1016\/j.clnesp.2021.07.021_bib7","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.yclnex.2020.07.002","article-title":"Practical guidance for the use of indirect calorimetry during COVID 19 pandemic","volume":"33","author":"Singer","year":"2020","journal-title":"Clinical nutrition experimental"},{"issue":"5","key":"10.1016\/j.clnesp.2021.07.021_bib8","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1016\/j.jcrc.2013.02.011","article-title":"Introducing a new generation indirect calorimeter for estimating energy requirements in adult intensive care unit patients: feasibility, practical considerations, and comparison with a mathematical equation","volume":"28","author":"De Waele","year":"2013","journal-title":"J\u00a0Crit Care"},{"issue":"1","key":"10.1016\/j.clnesp.2021.07.021_bib9","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.clnu.2014.01.008","article-title":"Evaluation of three indirect calorimetry devices in mechanically ventilated patients: which device compares best with the Deltatrac II\u00ae? A prospective observational study","volume":"34","author":"Graf","year":"2015","journal-title":"Clin Nutr"},{"issue":"3","key":"10.1016\/j.clnesp.2021.07.021_bib10","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1016\/j.clnu.2016.06.010","article-title":"Indirect calorimetry in nutritional therapy. A position paper by the ICALIC study group","volume":"36","author":"Oshima","year":"2017","journal-title":"Clin Nutr"},{"issue":"1","key":"10.1016\/j.clnesp.2021.07.021_bib11","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.clnu.2012.06.004","article-title":"Indirect calorimetry in mechanically ventilated patients. A systematic comparison of three instruments","volume":"32","author":"Sundstr\u00f6m","year":"2013","journal-title":"Clin Nutr"},{"key":"10.1016\/j.clnesp.2021.07.021_bib12","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.jcrc.2020.10.014","article-title":"Preventing infectious diseases in Intensive Care Unit by medical devices remote control: lessons from COVID-19","volume":"61","author":"Garzotto","year":"2021","journal-title":"J\u00a0Crit Care"},{"key":"10.1016\/j.clnesp.2021.07.021_bib13","first-page":"1","article-title":"How the Covid-19 epidemic is challenging our practice in clinical nutrition\u2014feedback from the field","author":"Thibault","year":"2020","journal-title":"Eur J Clin Nutr"},{"issue":"2","key":"10.1016\/j.clnesp.2021.07.021_bib14","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1177\/0148607110377903","article-title":"Validation of an equation for resting metabolic rate in older obese, critically ill patients","volume":"35","author":"Frankenfield","year":"2011","journal-title":"J\u00a0Parenter Enteral Nutr"},{"issue":"4","key":"10.1016\/j.clnesp.2021.07.021_bib15","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1177\/0148607104028004259","article-title":"Validation of 2 approaches to predicting resting metabolic rate in critically ill patients","volume":"28","author":"Frankenfield","year":"2004","journal-title":"J\u00a0Parenter Enteral Nutr"},{"issue":"1","key":"10.1016\/j.clnesp.2021.07.021_bib16","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1177\/0148607108322399","article-title":"Analysis of estimation methods for resting metabolic rate in critically ill adults","volume":"33","author":"Frankenfield","year":"2009","journal-title":"J\u00a0Parenter Enteral Nutr"},{"issue":"5","key":"10.1016\/j.clnesp.2021.07.021_bib17","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1177\/0148607115584001","article-title":"Validation of the Society of Critical Care Medicine and American Society for Parenteral and Enteral Nutrition recommendations for caloric provision to critically ill obese patients: a pilot study","volume":"40","author":"Mogensen","year":"2016","journal-title":"J\u00a0Parenter Enteral Nutr"},{"issue":"1","key":"10.1016\/j.clnesp.2021.07.021_bib18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13054-015-0737-8","article-title":"Metabolic and nutritional support of critically ill patients: consensus and controversies","volume":"19","author":"Preiser","year":"2015","journal-title":"Crit Care"},{"issue":"10","key":"10.1016\/j.clnesp.2021.07.021_bib19","doi-asserted-by":"crossref","first-page":"3105","DOI":"10.1016\/j.clnu.2020.01.017","article-title":"The clinical evaluation of the new indirect calorimeter developed by the ICALIC project","volume":"39","author":"Oshima","year":"2020","journal-title":"Clin Nutr"},{"key":"10.1016\/j.clnesp.2021.07.021_bib20","author":"Baxter"},{"issue":"9","key":"10.1016\/j.clnesp.2021.07.021_bib21","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1016\/S0002-8223(03)00982-9","article-title":"Validation of several established equations for resting metabolic rate in obese and nonobese people","volume":"103","author":"Frankenfield","year":"2003","journal-title":"J\u00a0Am Diet Assoc"},{"key":"10.1016\/j.clnesp.2021.07.021_bib22","series-title":"A\u00a0biometric study of basal metabolism in man","author":"Harris","year":"1919"},{"issue":"2","key":"10.1016\/j.clnesp.2021.07.021_bib23","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1093\/ajcn\/51.2.241","article-title":"A\u00a0new predictive equation for resting energy expenditure in healthy individuals","volume":"51","author":"Mifflin","year":"1990","journal-title":"Am J Clin Nutr"},{"issue":"2","key":"10.1016\/j.clnesp.2021.07.021_bib24","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1177\/096228029900800204","article-title":"Measuring agreement in method comparison studies","volume":"8","author":"Bland","year":"1999","journal-title":"Stat Methods Med Res"},{"issue":"7","key":"10.1016\/j.clnesp.2021.07.021_bib25","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1097\/00003246-199907000-00015","article-title":"Components of energy expenditure in patients with severe sepsis and major trauma: a basis for clinical care","volume":"27","author":"Uehara","year":"1999","journal-title":"Crit Care Med"},{"issue":"9","key":"10.1016\/j.clnesp.2021.07.021_bib26","doi-asserted-by":"crossref","first-page":"e799","DOI":"10.1097\/CCM.0000000000004457","article-title":"ICU and ventilator mortality among critically ill adults with coronavirus disease 2019","volume":"48","author":"Auld","year":"2020","journal-title":"Crit Care Med"},{"issue":"6189","key":"10.1016\/j.clnesp.2021.07.021_bib27","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/S0140-6736(00)79605-X","article-title":"Post-shock metabolic response","volume":"239","author":"Cuthbertson","year":"1942","journal-title":"Lancet"},{"issue":"2","key":"10.1016\/j.clnesp.2021.07.021_bib28","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1089\/sur.2015.184","article-title":"Persistent inflammation, immunosuppression, and catabolism: evolution of multiple organ dysfunction","volume":"17","author":"Rosenthal","year":"2016","journal-title":"Surg Infect"},{"issue":"1","key":"10.1016\/j.clnesp.2021.07.021_bib29","doi-asserted-by":"crossref","DOI":"10.1186\/s40560-021-00524-0","article-title":"Energy expenditure and indirect calorimetry in critical illness and convalescence: current evidence and practical considerations","volume":"9","author":"Moonen","year":"2021","journal-title":"Journal of Intensive Care"},{"key":"10.1016\/j.clnesp.2021.07.021_bib30","first-page":"1","article-title":"Global pandemics interconnected\u2014obesity, impaired metabolic health and COVID-19","author":"Stefan","year":"2021","journal-title":"Nat Rev Endocrinol"},{"key":"10.1016\/j.clnesp.2021.07.021_bib31","first-page":"1","article-title":"Is there an obesity paradox in critical illness? Epidemiologic and metabolic considerations","author":"Karampela","year":"2020","journal-title":"Current obesity reports"},{"key":"10.1016\/j.clnesp.2021.07.021_bib32","doi-asserted-by":"crossref","DOI":"10.1186\/s41038-017-0076-x","article-title":"Nutrition and metabolism in burn patients","volume":"5","author":"Clark","year":"2017","journal-title":"Burns & trauma"}],"container-title":["Clinical Nutrition ESPEN"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S240545772100276X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S240545772100276X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T06:59:12Z","timestamp":1762498752000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S240545772100276X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10]]},"references-count":32,"alternative-id":["S240545772100276X"],"URL":"https:\/\/doi.org\/10.1016\/j.clnesp.2021.07.021","relation":{},"ISSN":["2405-4577"],"issn-type":[{"value":"2405-4577","type":"print"}],"subject":[],"published":{"date-parts":[[2021,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prolonged progressive hypermetabolism during COVID-19 hospitalization undetected by common predictive energy equations","name":"articletitle","label":"Article Title"},{"value":"Clinical Nutrition ESPEN","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clnesp.2021.07.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Authors. Published by Elsevier Ltd on behalf of European Society for Clinical Nutrition and Metabolism.","name":"copyright","label":"Copyright"}]}}