{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T10:05:37Z","timestamp":1768644337336,"version":"3.49.0"},"reference-count":147,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100004512","name":"Cape Peninsula University of Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004512","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","clinicalnutritionespen.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Nutrition ESPEN"],"published-print":{"date-parts":[[2023,10]]},"DOI":"10.1016\/j.clnesp.2023.06.008","type":"journal-article","created":{"date-parts":[[2023,6,15]],"date-time":"2023-06-15T23:06:36Z","timestamp":1686870396000},"page":"77-88","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["The effects of tea polyphenols on emotional homeostasis: Understanding dementia risk through stress, mood, attention & sleep"],"prefix":"10.1016","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1243-1495","authenticated-orcid":false,"given":"Donn\u00e9","family":"Minn\u00e9","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8640-488X","authenticated-orcid":false,"given":"Juliet","family":"Stromin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2468-6054","authenticated-orcid":false,"given":"Taskeen","family":"Docrat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Penelope","family":"Engel-Hills","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1819-1699","authenticated-orcid":false,"given":"Jeanine L.","family":"Marnewick","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"10","key":"10.1016\/j.clnesp.2023.06.008_bib44","doi-asserted-by":"crossref","first-page":"2169","DOI":"10.1111\/jgs.15043","article-title":"Societal and family lifetime cost of dementia: implications for policy","volume":"65","author":"Jutkowitz","year":"2017","journal-title":"J\u00a0Am Geriatr Soc"},{"key":"10.1016\/j.clnesp.2023.06.008_bib18","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/s13024-019-0333-5","article-title":"The neuropathological diagnosis of Alzheimer's disease","volume":"14","author":"DeTure","year":"2019","journal-title":"Mol Neurodegener"},{"key":"10.1016\/j.clnesp.2023.06.008_bib97","doi-asserted-by":"crossref","unstructured":"Hofman A., Ott A., Breteler M.M., Bots M.L., Slooter A.J., van Harskamp F., et\u00a0al. Atherosclerosis, apolipoprotein E, and prevalence of dementia and Alzheimer's disease in the Rotterdam Study. Lancet. 1997 Jan 18;349(9046):151-4. doi: 10.1016\/S0140-6736(96)09328-2.","DOI":"10.1016\/S0140-6736(96)09328-2"},{"issue":"6","key":"10.1016\/j.clnesp.2023.06.008_bib98","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1179\/016164106X130506","article-title":"Update on hypertension and Alzheimer\u2019s disease","volume":"28","author":"Skoog","year":"2006","journal-title":"Neurol Res"},{"issue":"6","key":"10.1016\/j.clnesp.2023.06.008_bib12","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1017\/S0007114508047727","article-title":"Effects of dietary supplementation with the green tea polyphenol epigallocatechin-3-gallate on insulin resistance and associated metabolic risk factors: randomized controlled trial","volume":"101","author":"Brown","year":"2009","journal-title":"Br J Nutr"},{"issue":"2","key":"10.1016\/j.clnesp.2023.06.008_bib99","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1111\/obr.12629","article-title":"Obesity as a risk factor for Alzheimer\u2019s disease: weighing the evidence","volume":"19","author":"Alford","year":"2018","journal-title":"Obes Rev"},{"issue":"1","key":"10.1016\/j.clnesp.2023.06.008_bib100","doi-asserted-by":"crossref","first-page":"63","DOI":"10.3233\/JAD-2005-7107","article-title":"Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer\u2019s disease\u2013is this type 3 diabetes?","volume":"7","author":"Steen","year":"2005","journal-title":"J\u00a0Alzheimers Dis"},{"key":"10.1016\/j.clnesp.2023.06.008_bib101","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.ynstr.2018.05.003","article-title":"Chronic stress as a risk factor for Alzheimer\u2019s disease: roles of microglia-mediated synaptic remodelling, inflammation, and oxidative stress","volume":"9","author":"Bisht","year":"2018","journal-title":"Neurobiol Stress"},{"issue":"6","key":"10.1016\/j.clnesp.2023.06.008_bib102","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1515\/revneuro-2014-0035","article-title":"Chronic stress as a risk factor for Alzheimer\u2019s disease","volume":"25","author":"Machado","year":"2014","journal-title":"Rev Neurosci"},{"key":"10.1016\/j.clnesp.2023.06.008_bib160","doi-asserted-by":"crossref","unstructured":"Bhat, R., Crowe, E.P., Bitto, A., Moh, M., Katsetos, C.D., Garcia, F.U., Johnson, F.B., Trojanowski, J.Q., Sell, C. and Torres, C., 2012. Astrocyte senescence as a component of Alzheimer\u2019s disease.","DOI":"10.1371\/journal.pone.0045069"},{"issue":"7","key":"10.1016\/j.clnesp.2023.06.008_bib103","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1258\/ebm.2011.010355","article-title":"Vascular and metabolic dysfunction in Alzheimer\u2019s disease: a review","volume":"236","author":"Murray","year":"2011","journal-title":"Exp Biol Med (Maywood)"},{"key":"10.1016\/j.clnesp.2023.06.008_bib104","doi-asserted-by":"crossref","unstructured":"Kinney J.W., Bemiller S.M., Murtishaw A.S., Leisgang A.M., Salazar A.M., Lamb B.T. Inflammation as a central mechanism in Alzheimer's disease. Alzheimers Dement (NY). 2018 Sep 6;4(1):575-90. doi: 10.1016\/j.trci.2018.06.014.","DOI":"10.1016\/j.trci.2018.06.014"},{"key":"10.1016\/j.clnesp.2023.06.008_bib105","first-page":"240","volume":"1153","author":"Maccioni","year":"2009"},{"key":"10.1016\/j.clnesp.2023.06.008_bib106","doi-asserted-by":"crossref","unstructured":"Hooijmans C.R., Kiliaan A.J. Fatty acids, lipid metabolism and Alzheimer pathology. Eur J Pharmacol. 2008 May 6;585(1):176-96. doi: 10.1016\/j.ejphar.2007.11.081.","DOI":"10.1016\/j.ejphar.2007.11.081"},{"key":"10.1016\/j.clnesp.2023.06.008_bib107","doi-asserted-by":"crossref","unstructured":"Castellani R., Hirai K., Aliev G., Drew K.L., Nunomura A., Takeda A., et\u00a0al. Role of mitochondrial dysfunction in Alzheimer's disease. J Neurosci Res. 2002 Nov 1;70(3):357-60. doi: 10.1002\/jnr.10389.","DOI":"10.1002\/jnr.10389"},{"issue":"4","key":"10.1016\/j.clnesp.2023.06.008_bib108","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1007\/s00259-005-1762-7","article-title":"Brain glucose metabolism in the early and specific diagnosis of Alzheimer\u2019s disease. FDG-PET studies in MCI and AD","volume":"32","author":"Mosconi","year":"2005","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"10.1016\/j.clnesp.2023.06.008_bib161","doi-asserted-by":"crossref","unstructured":"Steen, E., Terry, B.M., J Rivera, E., Cannon, J.L., Neely, T.R., Tavares, R., Xu, X.J., Wands, J.R. and de la Monte, S.M., 2005. Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease\u2013is this type 3 diabetes?. Journal of Alzheimer's disease, 7(1), pp.63-80.","DOI":"10.3233\/JAD-2005-7107"},{"key":"10.1016\/j.clnesp.2023.06.008_bib109","doi-asserted-by":"crossref","unstructured":"Smith M.A., Rottkamp C.A., Nunomura A., Raina A.K., Perry G. Oxidative stress in Alzheimer\u2019s disease. Biochim Biophys Acta. 2000 Jul 26;1502(1):139-44. doi: 10.1016\/s0925-4439(00)00040-5.","DOI":"10.1016\/S0925-4439(00)00040-5"},{"key":"10.1016\/j.clnesp.2023.06.008_bib162","doi-asserted-by":"crossref","first-page":"101046","DOI":"10.1016\/j.arr.2020.101046","article-title":"Circadian and sleep dysfunction in Alzheimer\u2019s disease","volume":"60","author":"Uddin","year":"2020","journal-title":"Ageing Research Reviews"},{"key":"10.1016\/j.clnesp.2023.06.008_bib110","doi-asserted-by":"crossref","unstructured":"Vest R.S., Pike C.J. Gender, sex steroid hormones, and Alzheimer's disease. Horm Behav. 2013 Feb;63(2):301-7. doi: 10.1016\/j.yhbeh.2012.04.006.2. Tan ZS, Vasan RS. Thyroid function and Alzheimer's disease. J Alzheimers Dis. 2009 Mar 9;16(3):503-7. doi: 10.3233\/JAD-2009-0991.","DOI":"10.1016\/j.yhbeh.2012.04.006"},{"key":"10.1016\/j.clnesp.2023.06.008_bib111","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.neubiorev.2017.01.046","article-title":"Psychosocial stress on neuroinflammation and cognitive dysfunctions in Alzheimer\u2019s disease: the emerging role for microglia?","volume":"77","author":"Piirainen","year":"2017","journal-title":"Neurosci Biobehav Rev"},{"issue":"11","key":"10.1016\/j.clnesp.2023.06.008_bib24","first-page":"2405","article-title":"Quercetin reduces blood pressure in hypertensive subjects","volume":"137","author":"Edwards","year":"2007","journal-title":"J\u00a0Nutr"},{"issue":"12","key":"10.1016\/j.clnesp.2023.06.008_bib112","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1080\/13607863.2017.1387760","article-title":"Psychosocial risk factors and Alzheimer\u2019s disease: the associative effect of depression, sleep disturbance, and anxiety","volume":"22","author":"Burke","year":"2018","journal-title":"Aging Ment Health"},{"issue":"5","key":"10.1016\/j.clnesp.2023.06.008_bib113","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1192\/bjp.bp.112.118307","article-title":"Late-life depression and risk of vascular dementia and Alzheimer\u2019s disease: systematic review and meta-analysis of community-based cohort studies","volume":"202","author":"Diniz","year":"2013","journal-title":"Br. J. Psychiatry."},{"issue":"4","key":"10.1016\/j.clnesp.2023.06.008_bib114","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1016\/j.celrep.2019.03.099","article-title":"The major risk factors for Alzheimer\u2019s disease: age, sex, and genes modulate the microglia response to A\u03b2 plaques","volume":"27","author":"Frigerio","year":"2019","journal-title":"Cell Rep"},{"key":"10.1016\/j.clnesp.2023.06.008_bib115","doi-asserted-by":"crossref","unstructured":"Lindsay J, Laurin D, Verreault R, H\u00e9bert R, Helliwell B, Hill GB, et\u00a0al. Risk factors for Alzheimer\u2019s disease: a prospective analysis from the Canadian Study of Health and Aging. Am J Epidemiol. 2002 Sep 1;156(5):445-53. doi: 10.1093\/aje\/kwf074.3. Sharma P, Sharma A, Fayaz F, Wakode S, Pottoo FH. Biological signatures of Alzheimer\u2019s disease. Curr Top Med Chem. 2020;20(9):770-81. doi: 10.2174\/1568026620666200228095553.","DOI":"10.2174\/1568026620666200228095553"},{"key":"10.1016\/j.clnesp.2023.06.008_bib116","doi-asserted-by":"crossref","unstructured":"Fish PV, Steadman D, Bayle ED, Whiting P. New approaches for the treatment of Alzheimer\u2019s disease. Bioorg Med Chem Lett. 2019 Jan 15;29(2):125-33. doi: 10.1016\/j.bmcl.2018.11.034.","DOI":"10.1016\/j.bmcl.2018.11.034"},{"key":"10.1016\/j.clnesp.2023.06.008_bib46","first-page":"1572","article-title":"L-Theanine and caffeine in combination affect human cognition as evidenced by oscillatory alpha-band activity and attention task performance","volume":"138","author":"Kelly","year":"2008","journal-title":"J\u00a0Nutr"},{"issue":"5","key":"10.1016\/j.clnesp.2023.06.008_bib117","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1007\/s00401-020-02248-1","article-title":"The mechanistic link between selective vulnerability of the locus coeruleus and neurodegeneration in Alzheimer\u2019s disease","volume":"141","author":"Matchett","year":"2021","journal-title":"Acta Neuropathol"},{"issue":"8","key":"10.1016\/j.clnesp.2023.06.008_bib118","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1016\/j.pnpbp.2005.08.007","article-title":"Role of brain norepinephrine in the behavioral response to stress","volume":"29","author":"Morilak","year":"2005","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.clnesp.2023.06.008_bib119","doi-asserted-by":"crossref","first-page":"105602","DOI":"10.1016\/j.psyneuen.2021.105602","article-title":"Adverse childhood experiences and low socioeconomic status with respect to allostatic load in adulthood: a systematic review","volume":"136","author":"Misiak","year":"2022","journal-title":"Psychoneuroendocrinology"},{"issue":"4","key":"10.1016\/j.clnesp.2023.06.008_bib21","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1038\/aps.2009.24","article-title":"Molecular mechanisms of excitotoxicity and their relevance to pathogenesis of neurodegenerative diseases","volume":"30","author":"Dong","year":"2009","journal-title":"Acta Pharmacol Sin"},{"issue":"2","key":"10.1016\/j.clnesp.2023.06.008_bib73","first-page":"453","article-title":"Stress-induced tau phosphorylation: functional neuroplasticity or neuronal vulnerability?","volume":"18","author":"Rissman","year":"2009","journal-title":"J\u00a0Alzheim Dis : JAD"},{"issue":"12","key":"10.1016\/j.clnesp.2023.06.008_bib120","doi-asserted-by":"crossref","first-page":"2135","DOI":"10.1038\/jcbfm.2012.115","article-title":"The locus coeruleus-norepinephrine network optimizes coupling of cerebral blood volume with oxygen demand","volume":"32","author":"Bekar","year":"2012","journal-title":"J\u00a0Cereb Blood Flow Metab"},{"key":"10.1016\/j.clnesp.2023.06.008_bib121","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1111\/jnc.13447","article-title":"Causes, consequences, and cures for neuroinflammation mediated via the locus coeruleus: noradrenergic signaling system","volume":"Oct;139(Suppl 2):","author":"Feinstein","year":"2016","journal-title":"J\u00a0Neurochem"},{"issue":"5","key":"10.1016\/j.clnesp.2023.06.008_bib122","doi-asserted-by":"crossref","first-page":"2092","DOI":"10.1111\/j.1471-4159.2007.04888.x","article-title":"Neuroprotective actions of noradrenaline: effects on glutathione synthesis and activation of peroxisome proliferator activated receptor delta","volume":"103","author":"Madrigal","year":"2007","journal-title":"J\u00a0Neurochem"},{"issue":"26","key":"10.1016\/j.clnesp.2023.06.008_bib51","doi-asserted-by":"crossref","first-page":"43306","DOI":"10.18632\/oncotarget.17429","article-title":"Association between tea consumption and risk of cognitive disorders: a dose-response meta-analysis of observational studies","volume":"8","author":"Liu","year":"2017","journal-title":"Oncotarget"},{"issue":"3","key":"10.1016\/j.clnesp.2023.06.008_bib123","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1038\/ni.3102","article-title":"Innate immunity in Alzheimer\u2019s disease","volume":"16","author":"Heneka","year":"2015","journal-title":"Nat Immunol"},{"key":"10.1016\/j.clnesp.2023.06.008_bib124","doi-asserted-by":"crossref","unstructured":"Griciuc A, Tanzi RE. The role of innate immune genes in Alzheimer's disease. Curr Opin Neurol. 2021 Apr 1;34(2):228-36. doi: 10.1097\/WCO.0000000000000911.","DOI":"10.1097\/WCO.0000000000000911"},{"issue":"4","key":"10.1016\/j.clnesp.2023.06.008_bib125","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.3233\/JAD-2010-100018","article-title":"Implication of the immune system in Alzheimer\u2019s disease: evidence from genome-wide pathway analysis","volume":"20","author":"Lambert","year":"2010","journal-title":"J\u00a0Alzheimers Dis"},{"key":"10.1016\/j.clnesp.2023.06.008_bib126","doi-asserted-by":"crossref","unstructured":"Gomez-Nicola D, Boche D. Post-mortem analysis of neuroinflammatory changes in human Alzheimer\u2019s disease. Alzheimers Res Ther. 2015 Apr 22;7(1):1-8. doi: 10.1186\/s13195-015-0126-1.","DOI":"10.1186\/s13195-015-0126-1"},{"issue":"25","key":"10.1016\/j.clnesp.2023.06.008_bib127","doi-asserted-by":"crossref","first-page":"2766","DOI":"10.2174\/138161210793176572","article-title":"Neuroinflammation, oxidative stress and the pathogenesis of Alzheimer\u2019s disease","volume":"16","author":"Agostinho","year":"2010","journal-title":"Curr Pharm Des"},{"issue":"16\u201318","key":"10.1016\/j.clnesp.2023.06.008_bib128","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1089\/ars.2021.0177","article-title":"Altered metabolism in Alzheimer disease brain: role of oxidative stress","volume":"36","author":"Rummel","year":"2022","journal-title":"Antioxid Redox Signal"},{"key":"10.1016\/j.clnesp.2023.06.008_bib129","doi-asserted-by":"crossref","unstructured":"Friedberg JS, Aytan N, Cherry JD, Xia W, Standring OJ, Alvarez VE, et\u00a0al. Associations between brain inflammatory profiles and human neuropathology are altered based on apolipoprotein E \u03b54 genotype. Sci Rep. 2020 Feb 19;10(1):2924. doi: 10.1038\/s41598-020-59869-5.","DOI":"10.1038\/s41598-020-59869-5"},{"key":"10.1016\/j.clnesp.2023.06.008_bib65","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuint.2021.104987","article-title":"Neuroendocrine, neuroinflammatory and pathological outcomes of chronic stress: a story of microglial remodeling","volume":"145","author":"Picard","year":"2021","journal-title":"Neurochem Int"},{"issue":"11","key":"10.1016\/j.clnesp.2023.06.008_bib90","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1003830","article-title":"Consumption of coffee and tea and risk of developing stroke, dementia, and poststroke dementia: a cohort study in the UK Biobank","volume":"18","author":"Zhang","year":"2021","journal-title":"PLoS Med"},{"issue":"2","key":"10.1016\/j.clnesp.2023.06.008_bib130","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1016\/j.foodres.2012.12.052","article-title":"Progress in the analysis of selected tea constituents over the past 20 years","volume":"53","author":"Stodt","year":"2013","journal-title":"Food Res Int"},{"key":"10.1016\/j.clnesp.2023.06.008_bib8","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1007\/s00003-007-0246-z","article-title":"Green tea polyphenolic compounds and human health","volume":"2","author":"Barbosa","year":"2007","journal-title":"Journal f\u00fcr Verbraucherschutz und Lebensmittelsicherheit"},{"key":"10.1016\/j.clnesp.2023.06.008_bib131","series-title":"Tea: bioactivity and therapeutic potential","year":"2002"},{"key":"10.1016\/j.clnesp.2023.06.008_bib132","doi-asserted-by":"crossref","unstructured":"Singh BN, Shankar S, Srivastava RK. Green tea catechin, epigallocatechin-3-gallate (EGCG): mechanisms, perspectives and clinical applications. Biochem Pharmacol. 2011 Dec 15;82(12):1807-21. doi: 10.1016\/j.bcp.2011.07.093.","DOI":"10.1016\/j.bcp.2011.07.093"},{"issue":"5","key":"10.1016\/j.clnesp.2023.06.008_bib34","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/j.tiv.2005.10.010","article-title":"Anticlastogenic effects of black tea polyphenols theaflavins and thearubigins in human lymphocytes in\u00a0vitro","volume":"20","author":"Halder","year":"2006","journal-title":"Toxicol Vitro : an international journal published in association with BIBRA"},{"key":"10.1016\/j.clnesp.2023.06.008_bib134","doi-asserted-by":"crossref","unstructured":"Engelhardt UH. Tea chemistry \u2013 What do and what don\u2019t we know? \u2013 A micro review. Food Res Int. 2020 Jun 1;132:109120. doi: 10.1016\/j.foodres.2020.109120.","DOI":"10.1016\/j.foodres.2020.109120"},{"key":"10.1016\/j.clnesp.2023.06.008_bib40","doi-asserted-by":"crossref","first-page":"4032","DOI":"10.3390\/nu6104032","article-title":"Green tea consumption affects cognitive dysfunction in the elderly: a pilot study","volume":"6","author":"Ide","year":"2014","journal-title":"Nutrients"},{"key":"10.1016\/j.clnesp.2023.06.008_bib4","doi-asserted-by":"crossref","first-page":"115","DOI":"10.3945\/an.112.002717","article-title":"Epidemiologic evidence of a relationship between tea, coffee, or caffeine consumption and cognitive decline","volume":"4","author":"Arab","year":"2013","journal-title":"Adv Nutr"},{"issue":"3","key":"10.1016\/j.clnesp.2023.06.008_bib163","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1007\/s12603-014-0563-8","article-title":"Coffee, tea, and caffeine consumption and prevention of late-life cognitive decline and dementia: a systematic review","volume":"19","author":"Panza","year":"2015","journal-title":"The journal of nutrition, health & aging"},{"issue":"5","key":"10.1016\/j.clnesp.2023.06.008_bib135","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.3945\/ajcn.2009.28214","article-title":"Green tea consumption is associated with lower psychological distress in a general population: the Ohsaki Cohort 2006 Study","volume":"90","author":"Hozawa","year":"2009","journal-title":"Am J Clin Nutr"},{"issue":"6","key":"10.1016\/j.clnesp.2023.06.008_bib136","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.3945\/ajcn.2009.28216","article-title":"Green tea consumption is associated with depressive symptoms in the elderly","volume":"90","author":"Niu","year":"2009","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.clnesp.2023.06.008_bib137","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.foodres.2017.05.002","article-title":"An intervention study on the effect of matcha tea, in drink and snack bar formats, on mood and cognitive performance","volume":"Sep;99(Pt 1):","author":"Dietz","year":"2017","journal-title":"Food Res Int"},{"issue":"8","key":"10.1016\/j.clnesp.2023.06.008_bib138","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1079\/PHN2005752","article-title":"Green tea consumption in everyday life and mental health","volume":"8","author":"Shimbo","year":"2005","journal-title":"Public Health Nutr"},{"issue":"3","key":"10.1016\/j.clnesp.2023.06.008_bib82","doi-asserted-by":"crossref","first-page":"210","DOI":"10.3164\/jcbn.17-6","article-title":"Ingestion of green tea with lowered caffeine improves sleep quality of the elderly via suppression of stress","volume":"61","author":"Unno","year":"2017","journal-title":"J\u00a0Clin Biochem Nutr"},{"issue":"9","key":"10.1016\/j.clnesp.2023.06.008_bib93","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.3390\/nu10091201","article-title":"Green tea, coffee, and caffeine consumption are inversely associated with self-report lifetime depression in the Korean population","volume":"10","author":"Kim","year":"2018","journal-title":"Nutrients"},{"issue":"1","key":"10.1016\/j.clnesp.2023.06.008_bib89","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/1880-6805-33-20","article-title":"Intake of green tea inhibited increase of salivary chromogranin A after mental task stress loads","volume":"33","author":"Yoto","year":"2014","journal-title":"J\u00a0Physiol Anthropol"},{"issue":"6","key":"10.1016\/j.clnesp.2023.06.008_bib141","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.nutres.2012.05.007","article-title":"Green tea extract reduces blood pressure, inflammatory biomarkers, and oxidative stress and improves parameters associated with insulin resistance in obese, hypertensive patients","volume":"32","author":"Bogdanski","year":"2012","journal-title":"Nutr Res"},{"key":"10.1016\/j.clnesp.2023.06.008_bib142","first-page":"222","volume":"Vol. III.","author":"Fukino","year":"2001"},{"issue":"6","key":"10.1016\/j.clnesp.2023.06.008_bib55","doi-asserted-by":"crossref","first-page":"1473","DOI":"10.1038\/oby.2007.176","article-title":"A\u00a0green tea extract high in catechins reduces body fat and cardiovascular risks in humans","volume":"15","author":"Nagao","year":"2007","journal-title":"Obesity"},{"issue":"2","key":"10.1016\/j.clnesp.2023.06.008_bib56","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.nut.2008.07.018","article-title":"Standardized capsule of Camellia sinensis lowers cardiovascular risk factors in a randomized, double-blind, placebo-controlled study","volume":"25","author":"Nantz","year":"2009","journal-title":"Nutrition"},{"issue":"4","key":"10.1016\/j.clnesp.2023.06.008_bib37","doi-asserted-by":"crossref","first-page":"396S","DOI":"10.1080\/07315724.2007.10719628","article-title":"Can EGCG reduce abdominal fat in obese subjects?","volume":"26","author":"Hill","year":"2007","journal-title":"J\u00a0Am Coll Nutr"},{"issue":"1","key":"10.1016\/j.clnesp.2023.06.008_bib19","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.physbeh.2005.09.013","article-title":"Metabolic effects of green tea and of phases of weight loss","volume":"87","author":"Diepvens","year":"2006","journal-title":"Physiol Behav"},{"issue":"1","key":"10.1016\/j.clnesp.2023.06.008_bib29","first-page":"58","article-title":"Daily consumption of an aqueous green tea extract supplement does not impair liver function or alter cardiovascular disease risk biomarkers in healthy men","volume":"139","author":"Frank","year":"2009","journal-title":"J\u00a0Nutr"},{"key":"10.1016\/j.clnesp.2023.06.008_bib143","doi-asserted-by":"crossref","unstructured":"Baba Y, Inagaki S, Nakagawa S, Kaneko T, Kobayashi M, Takihara T. Effect of daily intake of green tea catechins on cognitive function in middle-aged and older subjects: a randomized, placebo-controlled study. Molecules. 2020 Sep 17;25(18):4265. doi: 10.3390\/molecules25184265.","DOI":"10.3390\/molecules25184265"},{"issue":"4","key":"10.1016\/j.clnesp.2023.06.008_bib61","article-title":"A\u00a0combination of green tea extract and L-theanin improves memory and attention in subjects with mild cognitive imparimetn: a double-blind placebo-controlled study","volume":"14","author":"Park","year":"2011","journal-title":"J\u00a0Med Food"},{"issue":"2","key":"10.1016\/j.clnesp.2023.06.008_bib15","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.appet.2010.12.011","article-title":"Black Tea improves attention and self-reported alertness","volume":"56","author":"De Bruin","year":"2011","journal-title":"Appetite"},{"issue":"2","key":"10.1016\/j.clnesp.2023.06.008_bib26","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/j.appet.2010.01.003","article-title":"L-theanine and caffeine improve task-switching but not intersensory attention or subjective alertness","volume":"54","author":"Ein\u00f6ther","year":"2010","journal-title":"Appetite"},{"key":"10.1016\/j.clnesp.2023.06.008_bib30","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1179\/147683010X12611460764840","article-title":"The combination of L-theanine and caffeine improves cognitive performance and increases subjective alertness","volume":"13","author":"Giesbrecht","year":"2010","journal-title":"Nutr Neurosci"},{"key":"10.1016\/j.clnesp.2023.06.008_bib60","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1179\/147683008X301513","article-title":"The combined effects of L-theanine and caffeine on cognitive performance and mood","volume":"11","author":"Owen","year":"2008","journal-title":"Nutr Neurosci"},{"key":"10.1016\/j.clnesp.2023.06.008_bib28","doi-asserted-by":"crossref","first-page":"3933","DOI":"10.1097\/00001756-199812010-00030","article-title":"Parieto-occipital \u223c10 Hz activity reflects anticipatory state of visual attention mechanism","volume":"9","author":"Foxe","year":"1998","journal-title":"Neuroreport"},{"key":"10.1016\/j.clnesp.2023.06.008_bib35","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.biopsycho.2007.09.008","article-title":"The effects of L-theanine, caffeine and their combination on cognition and mood","volume":"77","author":"Haskell","year":"2008","journal-title":"Biol Psychol"},{"issue":"7","key":"10.1016\/j.clnesp.2023.06.008_bib83","doi-asserted-by":"crossref","first-page":"777","DOI":"10.3390\/nu9070777","article-title":"Reduced stress and improved sleep quality caused by green tea are associated with a reduced caffeine content","volume":"9","author":"Unno","year":"2017","journal-title":"Nutrients"},{"issue":"3","key":"10.1016\/j.clnesp.2023.06.008_bib144","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1007\/s12603-020-1526-x","article-title":"Tea consumption and depression from follow up in the Singapore Longitudinal Ageing Study","volume":"25","author":"Ng","year":"2021","journal-title":"J\u00a0Nutr Health Aging"},{"key":"10.1016\/j.clnesp.2023.06.008_bib38","doi-asserted-by":"crossref","first-page":"27","DOI":"10.3389\/fnut.2019.00027","article-title":"Effect of GABA-fortified oolong tea on reducing stress in a university student cohort","volume":"6","author":"Hinton","year":"2019","journal-title":"Front Nutr"},{"issue":"14","key":"10.1016\/j.clnesp.2023.06.008_bib87","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1001\/archinte.164.14.1534","article-title":"The protective effect of habitual tea consumption on hypertension","volume":"164","author":"Yang","year":"2004","journal-title":"Arch Intern Med"},{"issue":"14","key":"10.1016\/j.clnesp.2023.06.008_bib88","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1001\/archinte.164.14.1534","article-title":"The protective effect of habitual tea consumption on hypertension","volume":"164","author":"Yang","year":"2004","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.clnesp.2023.06.008_bib68","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/S0091-3057(00)00192-1","article-title":"The acute physiological and mood effects of tea and coffee the role of caffeine level","volume":"66","author":"Quinlan","year":"2000","journal-title":"Pharmacol Biochem Behav"},{"issue":"2","key":"10.1016\/j.clnesp.2023.06.008_bib5","doi-asserted-by":"crossref","first-page":"858","DOI":"10.4314\/ahs.v21i2.47","article-title":"Effects of black tea consumption and caffeine intake on depression risk in black tea consumers","volume":"21","author":"Asil","year":"2021","journal-title":"Afr Health Sci"},{"key":"10.1016\/j.clnesp.2023.06.008_bib79","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/s00213-006-0573-2","article-title":"The effects of tea on psychophysiological stress responsivity and post-stress recovery: a randomised double-blind trial","volume":"190","author":"Steptoe","year":"2007","journal-title":"Psychopharmacology"},{"issue":"2","key":"10.1016\/j.clnesp.2023.06.008_bib39","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1001\/archinte.172.2.186","article-title":"Effects of black tea on blood pressure: a randomised controlled trial","volume":"177","author":"Hodgson","year":"2012","journal-title":"Arch Intern Med"},{"issue":"1","key":"10.1016\/j.clnesp.2023.06.008_bib95","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s40816-017-0049-4","article-title":"The effect of black tea on human cognitive performance in a cognitive test battery","volume":"3","author":"Rizwan","year":"2017","journal-title":"Clinical Phytoscience"},{"issue":"11","key":"10.1016\/j.clnesp.2023.06.008_bib91","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1038\/ejcn.2012.105","article-title":"Neural effects of green tea extract on dorsolateral prefrontal cortex","volume":"66","author":"Borgwardt","year":"2012","journal-title":"Eur J Clin Nutr"},{"issue":"10","key":"10.1016\/j.clnesp.2023.06.008_bib36","doi-asserted-by":"crossref","first-page":"2362","DOI":"10.3390\/nu11102362","article-title":"Effects of L-theanine administration on stress-related symptoms and cognitive functions in healthy adults: a randomized controlled trial","volume":"11","author":"Hidese","year":"2019","journal-title":"Nutrients"},{"issue":"7","key":"10.1016\/j.clnesp.2023.06.008_bib52","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1002\/hup.611","article-title":"The acute effects of L-theanine in comparison with alprazolam on anticipatory anxiety in humans","volume":"19","author":"Lu","year":"2004","journal-title":"Hum Psychopharmacol"},{"issue":"1","key":"10.1016\/j.clnesp.2023.06.008_bib74","doi-asserted-by":"crossref","first-page":"34","DOI":"10.4088\/JCP.09m05324gre","article-title":"L-theanine relieves positive, activation, and anxiety symptoms in patients with schizophrenia and schizoaffective disorder: an 8-week, randomized, double-blind, placebo-controlled, 2-center study","volume":"72","author":"Ritsner","year":"2011","journal-title":"J\u00a0Clin Psychiatry"},{"issue":"1","key":"10.1016\/j.clnesp.2023.06.008_bib84","doi-asserted-by":"crossref","first-page":"53","DOI":"10.3390\/nu8010053","article-title":"Anti-stress, behavioural and magnetoencephalography effects of an L-theanine-based nutrient drink: a randomised, double-blind, placebo-controlled, crossover trial","volume":"8","author":"White","year":"2016","journal-title":"Nutrients"},{"issue":"1","key":"10.1016\/j.clnesp.2023.06.008_bib47","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.biopsycho.2006.06.006","article-title":"L-Theanine reduces psychological and physiological stress responses","volume":"74","author":"Kimura","year":"2007","journal-title":"Biol Psychol"},{"issue":"1","key":"10.1016\/j.clnesp.2023.06.008_bib32","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1007\/s10548-008-0068-z","article-title":"The effects of L-theanine on alpha-band oscillatory brain activity during a visuo-spatial attention task","volume":"22","author":"Gomez-Ramirez","year":"2009","journal-title":"Brain Topogr"},{"issue":"Suppl 1","key":"10.1016\/j.clnesp.2023.06.008_bib57","first-page":"167","article-title":"L-theanine, a natural constituent in tea, and its effect on mental state","volume":"17","author":"Nobre","year":"2008","journal-title":"Asia Pac J Clin Nutr"},{"issue":"1","key":"10.1016\/j.clnesp.2023.06.008_bib31","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1097\/01.WNF.0000240940.13876.17","article-title":"The deployment of intersensory selective attention: a high-density electrical mapping study of the effects of theanine","volume":"30","author":"Gomez-Ramirez","year":"2007","journal-title":"Clin Neuropharmacol"},{"issue":"5","key":"10.1016\/j.clnesp.2023.06.008_bib71","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1080\/07315724.2014.926153","article-title":"In search of a safe natural sleep aid","volume":"34","author":"Rao","year":"2015","journal-title":"J\u00a0Am Coll Nutr"},{"issue":"5","key":"10.1016\/j.clnesp.2023.06.008_bib59","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1017\/neu.2015.22","article-title":"Effect of L-theanine on glutamatergic function in patients with schizophrenia","volume":"27","author":"Ota","year":"2015","journal-title":"Acta Neuropsychiatr"},{"key":"10.1016\/j.clnesp.2023.06.008_bib13","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0165-1781(89)90047-4","article-title":"The Pittsburgh sleep quality index: a new instrument for psychiatric practice and research","volume":"28","author":"Buysse","year":"1989","journal-title":"Psychiatr Res"},{"issue":"4","key":"10.1016\/j.clnesp.2023.06.008_bib54","first-page":"348","article-title":"The effects of L-theanine (Suntheanine\u00ae) on objective sleep quality in boys with attention deficit hyperactivity disorder (ADHD): a randomized, double-blind, placebo-controlled clinical trial","volume":"16","author":"Lyon","year":"2011","journal-title":"Alternative Med Rev : a journal of clinical therapeutic"},{"issue":"2","key":"10.1016\/j.clnesp.2023.06.008_bib86","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1002\/hup.1263","article-title":"Epigallocatechin gallate, cerebral blood flow parameters, cognitive performance and mood in healthy humans: a double-blind, placebo-controlled, crossover investigation","volume":"27","author":"Wightman","year":"2012","journal-title":"Hum Psychopharmacol"},{"key":"10.1016\/j.clnesp.2023.06.008_bib63","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1017\/S1368980013000360","article-title":"Green tea and coffee consumption is inversely associated with depressive symptoms in a Japanese working population","volume":"17","author":"Pham","year":"2014","journal-title":"Publ Health Nutr"},{"issue":"17","key":"10.1016\/j.clnesp.2023.06.008_bib53","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1001\/archinternmed.2011.393","article-title":"Coffee, caffeine, and risk of depression among women","volume":"171","author":"Lucas","year":"2011","journal-title":"Arch Intern Med"},{"issue":"9","key":"10.1016\/j.clnesp.2023.06.008_bib81","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1023\/A:1007614714579","article-title":"Heavy coffee drinking and the risk of suicide","volume":"16","author":"Tanskanen","year":"2000","journal-title":"Eur J Epidemiol"},{"issue":"2","key":"10.1016\/j.clnesp.2023.06.008_bib43","doi-asserted-by":"crossref","first-page":"111","DOI":"10.4082\/kjfm.2016.37.2.111","article-title":"The relationship of caffeine intake with depression, anxiety, stress, and sleep in Korean adolescents","volume":"37","author":"Jin","year":"2016","journal-title":"Korean journal of family medicine"},{"issue":"3","key":"10.1016\/j.clnesp.2023.06.008_bib2","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1007\/s00213-009-1668-3","article-title":"A\u00a0comparison of the effects of caffeine following abstinence and normal caffeine use","volume":"207","author":"Addicott","year":"2009","journal-title":"Psychopharmacology"},{"issue":"3\u20134","key":"10.1016\/j.clnesp.2023.06.008_bib76","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1007\/s00213-004-1935-2","article-title":"Cognitive and physiological effects of an \"energy drink\": an evaluation of the whole drink and of glucose, caffeine and herbal flavouring fractions","volume":"176","author":"Scholey","year":"2004","journal-title":"Psychopharmacology"},{"issue":"5 Pt 1","key":"10.1016\/j.clnesp.2023.06.008_bib78","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/S0895-7061(99)00217-4","article-title":"Additive pressor effects of caffeine and stress in male medical students at risk for hypertension","volume":"13","author":"Shepard","year":"2000","journal-title":"Am J Hypertens"},{"issue":"7","key":"10.1016\/j.clnesp.2023.06.008_bib17","doi-asserted-by":"crossref","first-page":"741","DOI":"10.3390\/nu9070741","article-title":"Coffee consumption and heart rate variability: the Brazilian longitudinal study of adult health (ELSA-Brasil) cohort study","volume":"9","author":"de Oliveira","year":"2017","journal-title":"Nutrients"},{"issue":"7","key":"10.1016\/j.clnesp.2023.06.008_bib11","doi-asserted-by":"crossref","first-page":"1922","DOI":"10.3390\/nu12071922","article-title":"Caffeine-containing, adaptogenic-rich drink modulates the effects of caffeine on mental performance and cognitive parameters: a double-blinded, placebo-controlled, randomized trial","volume":"12","author":"Boolani","year":"2020","journal-title":"Nutrients"},{"issue":"25","key":"10.1016\/j.clnesp.2023.06.008_bib48","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1002\/hup.1126","article-title":"Caffeine and stress alter salivary a-amylase activity in young men","volume":"5","author":"Klein","year":"2010","journal-title":"Hum Psychopharmacol Clin Exp"},{"key":"10.1016\/j.clnesp.2023.06.008_bib3","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1097\/00006842-199807000-00021","article-title":"Hypothalamic\u2013pituitaryadrenocortical responses to psychological stress and caffeine in men at high risk for hypertension","volume":"60","author":"al'Absi","year":"1998","journal-title":"Psychosom Med"},{"key":"10.1016\/j.clnesp.2023.06.008_bib66","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/0002-9149(85)90578-8","article-title":"Effects of caffeine on vascular resistance, cardiac output and myocardial contractility in young men","volume":"56","author":"Pincomb","year":"1985","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.clnesp.2023.06.008_bib64","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1111\/j.1475-097X.1994.tb00400.x","article-title":"Effect of acute dose of caffeine on cardiovascular autonomic responses in healthy subjects","volume":"14","author":"Piha","year":"1994","journal-title":"Clin Physiol"},{"issue":"13","key":"10.1016\/j.clnesp.2023.06.008_bib80","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1016\/0002-9149(90)91435-9","article-title":"Effects of caffeine on blood pressure response during exercise in normotensive healthy young men","volume":"65","author":"Sung","year":"1990","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.clnesp.2023.06.008_bib85","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1016\/0002-9149(84)90525-3","article-title":"Cardiovascular effects of coffee and caffeine","volume":"53 7","author":"Whitsett","year":"1984","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.clnesp.2023.06.008_bib41","first-page":"159","article-title":"Chronic effects of habitual caffeine consumption on laboratory and ambulatory blood pressure levels","volume":"1","author":"James","year":"1994","journal-title":"J\u00a0Cardiovasc Risk"},{"issue":"2\u20133","key":"10.1016\/j.clnesp.2023.06.008_bib7","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/0021-9150(90)90170-N","article-title":"Coffee, caffeine and hemostasis: results from two randomized studies","volume":"83","author":"Bak","year":"1990","journal-title":"Atherosclerosis"},{"issue":"11","key":"10.1016\/j.clnesp.2023.06.008_bib22","article-title":"Caffeine effects on sleep taken 0, 3, or 6 hours before going to bed","volume":"9","author":"Drake","year":"2013","journal-title":"J\u00a0Clin Sleep Med"},{"issue":"2","key":"10.1016\/j.clnesp.2023.06.008_bib23","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1111\/j.1365-2869.2006.00518.x","article-title":"Challenging sleep in aging: the effects of 200mg of caffeine during the evening in young and middle-aged moderate caffeine consumers","volume":"15","author":"Drapeau","year":"2006","journal-title":"J\u00a0Sleep Res"},{"key":"10.1016\/j.clnesp.2023.06.008_bib20","doi-asserted-by":"crossref","DOI":"10.1089\/jcr.2016.0023","article-title":"The effect of coffee and caffeine on mood, sleep, and health-related quality of life","author":"Distelberg","year":"2017","journal-title":"J\u00a0Caffeine Res"},{"issue":"11\u201312","key":"10.1016\/j.clnesp.2023.06.008_bib14","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1016\/j.nut.2016.04.005","article-title":"Caffeine consumption, insomnia, and sleep duration: results from a nationally representative sample","volume":"32","author":"Chaudhary","year":"2016","journal-title":"Nutrition"},{"key":"10.1016\/j.clnesp.2023.06.008_bib94","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.jchromb.2005.12.043","article-title":"Determination of St. John's wort flavonoid-metabolites in rat brain through high performance liquid chromatography coupled with fluorescence detection","volume":"832","author":"Paulke","year":"2006","journal-title":"J\u00a0Chromatogr, B: Anal Technol Biomed Life Sci"},{"key":"10.1016\/j.clnesp.2023.06.008_bib92","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/j.neulet.2006.06.010","article-title":"Protective effect of quercetin, a natural flavonoid against neuronal damage after transient global cerebral ischemia","volume":"404","author":"Cho","year":"2006","journal-title":"Neurosci Lett"},{"issue":"15","key":"10.1016\/j.clnesp.2023.06.008_bib96","doi-asserted-by":"crossref","first-page":"7116","DOI":"10.3390\/app11157116","article-title":"Role of quercetin in depressive-like behaviors: findings from animal models","volume":"11","author":"Silvestro","year":"2021","journal-title":"Appl Sci"},{"key":"10.1016\/j.clnesp.2023.06.008_bib10","doi-asserted-by":"crossref","DOI":"10.1007\/s13668-015-0137-3","article-title":"The efficacy of quercetin in cardiovascular health","volume":"4","author":"Bondonno","year":"2015","journal-title":"Current Nutrition Reports"},{"issue":"8","key":"10.1016\/j.clnesp.2023.06.008_bib50","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/j.nutres.2012.06.018","article-title":"Acute, quercetin-induced reductions in blood pressure in hypertensive individuals are not secondary to lower plasma angiotensin-converting enzyme activity or endothelin-1: nitric oxide","volume":"32","author":"Larson","year":"2012","journal-title":"Nutr Res (NY)"},{"issue":"7","key":"10.1016\/j.clnesp.2023.06.008_bib25","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1017\/S0007114509359127","article-title":"Quercetin reduces systolic blood pressure and plasma oxidised low-density lipoprotein concentrations in overweight subjects with a high-cardiovascular disease risk phenotype: a double-blinded, placebo-controlled cross-over study","volume":"102","author":"Egert","year":"2009","journal-title":"Br J Nutr"},{"issue":"1","key":"10.1016\/j.clnesp.2023.06.008_bib42","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1080\/07315724.2016.1140093","article-title":"The effect of quercetin on inflammatory factors and clinical symptoms in women with rheumatoid arthritis: a double-blind, randomized controlled trial","volume":"36","author":"Javadi","year":"2017","journal-title":"J\u00a0Am Coll Nutr"},{"key":"10.1016\/j.clnesp.2023.06.008_bib77","doi-asserted-by":"crossref","first-page":"53","DOI":"10.2147\/OAJSM.S39632","article-title":"Long-term quercetin supplementation reduces lipid peroxidation but does not improve performance in endurance runners","volume":"4","author":"Scholten","year":"2013","journal-title":"Open Access J Sports Med"},{"issue":"5","key":"10.1016\/j.clnesp.2023.06.008_bib145","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.3390\/nu11051165","article-title":"Green tea intake and risks for dementia, Alzheimer\u2019s disease, mild cognitive impairment, and cognitive impairment: a systematic review","volume":"11","author":"Kakutani","year":"2019","journal-title":"Nutrients"},{"key":"10.1016\/j.clnesp.2023.06.008_bib146","doi-asserted-by":"crossref","unstructured":"Mancini E, Beglinger C, Drewe J, Zanchi D, Lang UE, Borgwardt S. Green tea effects on cognition, mood and human brain function: a systematic review. Phytomedicine. 2017 Oct 15;34:26-37. doi: 10.1016\/j.phymed.2017.07.008.","DOI":"10.1016\/j.phymed.2017.07.008"},{"key":"10.1016\/j.clnesp.2023.06.008_bib164","doi-asserted-by":"crossref","unstructured":"Enogieru, A.B., Haylett, W., Hiss, D.C., Bardien, S. and Ekpo, O.E., 2018. Rutin as a potent antioxidant: Implications for neurodegenerative disorders. Oxidative Medicine and Cellular Longevity, 2018.","DOI":"10.1155\/2018\/6241017"},{"key":"10.1016\/j.clnesp.2023.06.008_bib148","doi-asserted-by":"crossref","unstructured":"Unno K, Noda S, Kawasaki Y, Yamada H, Morita A, Iguchi K, et\u00a0al. Reduced stress and improved sleep quality caused by green tea are associated with a reduced caffeine content. Nutrients. 2017 Jul 19; 9(7):777. doi: 10.3390\/nu9070777.","DOI":"10.3390\/nu9070777"},{"key":"10.1016\/j.clnesp.2023.06.008_bib149","first-page":"165","article-title":"Revision of the genus Aspalathus","volume":"121","author":"Dahlgren","year":"1968","journal-title":"Bot Not"},{"key":"10.1016\/j.clnesp.2023.06.008_bib165","doi-asserted-by":"crossref","first-page":"e47","DOI":"10.1017\/jns.2016.41","article-title":"Flavonoids: an overview","volume":"5","author":"Panche","year":"2016","journal-title":"Journal of nutritional science"},{"issue":"7","key":"10.1016\/j.clnesp.2023.06.008_bib166","doi-asserted-by":"crossref","first-page":"841","DOI":"10.2174\/1389450118666171109150731","article-title":"Main isoflavones found in dietary sources as natural anti-inflammatory agents","volume":"19","author":"Danciu","year":"2018","journal-title":"Current drug targets"},{"key":"10.1016\/j.clnesp.2023.06.008_bib1","series-title":"I\u00a0Laher, Chapter 181 entitled \u201cAntioxidant properties of Rooibos (Aspalathus linearis): in\u00a0vitro and in\u00a0vivo evidence\u201c","first-page":"4083","article-title":"Chapter in book: \u201csystems biology of free radicals and antioxidants\u201c by springer reference work Part XVII","author":"Marnewick","year":"2014"},{"issue":"8","key":"10.1016\/j.clnesp.2023.06.008_bib150","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1007\/s00394-006-0620-0","article-title":"Selective bronchodilatory effect of Rooibos tea (Aspalathus linearis) and its flavonoid, chrysoeriol","volume":"45","author":"Khan","year":"2006","journal-title":"Eur J Nutr"},{"issue":"4","key":"10.1016\/j.clnesp.2023.06.008_bib151","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1016\/j.sajb.2011.07.004","article-title":"Rooibos (Aspalathus linearis) beyond the farm gate: from herbal tea to potential phytopharmaceutical","volume":"77","author":"Joubert","year":"2011","journal-title":"S\u00a0Afr J Bot"},{"issue":"1","key":"10.1016\/j.clnesp.2023.06.008_bib152","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/ptr.1992","article-title":"A\u00a0review of the bioactivity of South African herbal teas: Rooibos (Aspalathus linearis) and Honeybush (Cyclopia intermedia)","volume":"21","author":"McKay","year":"2007","journal-title":"Phytother Res"},{"key":"10.1016\/j.clnesp.2023.06.008_bib154","unstructured":"Mangwana N. The in\u00a0vitro faecal evaluation of prebiotic effects of Rooibos phenolic compounds on the gut microbiota of vervet monkeys (Chlorocebus pygerythrus) [master\u2019s dissertation]. Cape Town, South Africa: Cape Peninsula University of Technology; 2020 Mar. Available from: https:\/\/etd.cput.ac.za\/bitstream\/20.500."},{"issue":"5","key":"10.1016\/j.clnesp.2023.06.008_bib155","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1017\/S1368980010000170","article-title":"Effects of green tea, black tea and Rooibos tea on angiotensin-converting enzyme and nitric oxide in healthy volunteers","volume":"13","author":"Persson","year":"2010","journal-title":"Public Health Nutr"},{"key":"10.1016\/j.clnesp.2023.06.008_bib156","unstructured":"Van Vuuren MA. An investigation into the anti-hypertensive effects of Green Rooibos Tea Extract (GRT) [doctoral dissertation]. Stellenbosch, South Africa: Stellenbosch University; 2019. Available from: http:\/\/hdl.handle.net\/10019.1\/105633."},{"key":"10.1016\/j.clnesp.2023.06.008_bib157","doi-asserted-by":"crossref","unstructured":"Schloms L, Swart AC. Rooibos flavonoids inhibit the activity of key adrenal steroidogenic enzymes, modulating steroid hormone levels in H295R cells. Molecules. 2014 Mar 24;19(3):3681-95. doi: 10.3390\/molecules19033681.","DOI":"10.3390\/molecules19033681"},{"issue":"6","key":"10.1016\/j.clnesp.2023.06.008_bib158","doi-asserted-by":"crossref","first-page":"505","DOI":"10.4162\/nrp.2012.6.6.505","article-title":"Improvement of andropause symptoms by dandelion and Rooibos extract complex CRS-10 in aging male","volume":"6","author":"Noh","year":"2012","journal-title":"Nutr Res Pract"},{"issue":"8","key":"10.1016\/j.clnesp.2023.06.008_bib159","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1016\/S0149-2918(01)80109-0","article-title":"A\u00a0systematic review of the associations between dose regimens and medication compliance","volume":"23","author":"Claxton","year":"2001","journal-title":"Clin Ther"}],"container-title":["Clinical Nutrition ESPEN"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405457723001523?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405457723001523?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T07:08:18Z","timestamp":1762499298000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2405457723001523"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10]]},"references-count":147,"alternative-id":["S2405457723001523"],"URL":"https:\/\/doi.org\/10.1016\/j.clnesp.2023.06.008","relation":{},"ISSN":["2405-4577"],"issn-type":[{"value":"2405-4577","type":"print"}],"subject":[],"published":{"date-parts":[[2023,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The effects of tea polyphenols on emotional homeostasis: Understanding dementia risk through stress, mood, attention & sleep","name":"articletitle","label":"Article Title"},{"value":"Clinical Nutrition ESPEN","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clnesp.2023.06.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}