{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T06:54:41Z","timestamp":1791960881613,"version":"4.3.4"},"reference-count":22,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["22K11839"],"award-info":[{"award-number":["22K11839"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","clinicalkey.com","clinicalnutritionespen.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Nutrition ESPEN"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.clnesp.2024.10.162","type":"journal-article","created":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T16:53:05Z","timestamp":1730479985000},"page":"435-440","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Low handgrip strength as a marker of severity in the diagnostic criteria for cancer cachexia"],"prefix":"10.1016","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2246-9526","authenticated-orcid":false,"given":"Tatsuma","family":"Sakaguchi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keisuke","family":"Maeda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoko","family":"Takeuchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuria","family":"Ishida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryoko","family":"Kato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junko","family":"Ueshima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akio","family":"Shimizu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayano","family":"Nagano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koki","family":"Kawamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koji","family":"Amano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoharu","family":"Mori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.clnesp.2024.10.162_bib1","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1038\/s41571-023-00734-5","article-title":"Cancer-associated cachexia \u2014 understanding the tumour macroenvironment and microenvironment to improve management","volume":"20","author":"Argil\u00e9s","year":"2023","journal-title":"Nat Rev Clin Oncol"},{"issue":"5","key":"10.1016\/j.clnesp.2024.10.162_bib2","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1002\/jcsm.12117","article-title":"Cachexia research in Japan: facts and numbers on prevalence, incidence and clinical impact","volume":"7","author":"Konishi","year":"2016","journal-title":"J\u00a0Cachexia Sarcopenia Muscle"},{"issue":"5","key":"10.1016\/j.clnesp.2024.10.162_bib3","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1002\/jcsm.12167","article-title":"Prevalence and clinical impact of cachexia in chronic illness in Europe, USA, and Japan: facts and numbers update 2016","volume":"7","author":"von Haehling","year":"2016","journal-title":"J\u00a0Cachexia Sarcopenia Muscle"},{"issue":"6","key":"10.1016\/j.clnesp.2024.10.162_bib4","doi-asserted-by":"crossref","first-page":"2683","DOI":"10.1002\/jcsm.13105","article-title":"Identification and management of cancer cachexia in patients: assessment of healthcare providers' knowledge and practice gaps","volume":"13","author":"Baracos","year":"2022","journal-title":"J\u00a0Cachexia Sarcopenia Muscle"},{"issue":"1","key":"10.1016\/j.clnesp.2024.10.162_bib5","first-page":"167","article-title":"Sarcopenia and cachexia evaluation in different healthcare settings: a questionnaire survey of health professionals","volume":"27","author":"Nakahara","year":"2018","journal-title":"Asia Pac J Clin Nutr"},{"issue":"5","key":"10.1016\/j.clnesp.2024.10.162_bib6","doi-asserted-by":"crossref","first-page":"1949","DOI":"10.1002\/jcsm.13323","article-title":"Diagnosis and outcomes of cachexia in Asia: working consensus report from the Asian working group for cachexia","volume":"14","author":"Arai","year":"2023","journal-title":"J\u00a0Cachexia Sarcopenia Muscle"},{"issue":"1","key":"10.1016\/j.clnesp.2024.10.162_bib7","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1002\/jcsm.13408","article-title":"Validity of the diagnostic criteria from the Asian working group for cachexia in advanced cancer","volume":"15","author":"Sakaguchi","year":"2024","journal-title":"J\u00a0Cachexia Sarcopenia Muscle"},{"issue":"5","key":"10.1016\/j.clnesp.2024.10.162_bib8","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/S1470-2045(10)70218-7","article-title":"Definition and classification of cancer cachexia: an international consensus","volume":"12","author":"Fearon","year":"2011","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.clnesp.2024.10.162_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.nut.2023.112152","article-title":"Association of body mass index and weight change with death in patients with advanced cancer","volume":"115","author":"Ishida","year":"2023","journal-title":"Nutrition"},{"issue":"1","key":"10.1016\/j.clnesp.2024.10.162_bib10","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1200\/JCO.2014.56.1894","article-title":"Diagnostic criteria for the classification of cancer-associated weight loss","volume":"33","author":"Martin","year":"2015","journal-title":"J\u00a0Clin Oncol"},{"issue":"5","key":"10.1016\/j.clnesp.2024.10.162_bib11","doi-asserted-by":"crossref","first-page":"2090","DOI":"10.1002\/jcsm.13287","article-title":"Development and applicability of modified weight loss grading system in cancer: a real-world cohort study","volume":"14","author":"Xie","year":"2023","journal-title":"J\u00a0Cachexia Sarcopenia Muscle"},{"issue":"2","key":"10.1016\/j.clnesp.2024.10.162_bib12","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1080\/01635581.2020.1750662","article-title":"The correlation between hand grip strength and nutritional variables in ambulatory cancer patients","volume":"73","author":"Pereira","year":"2021","journal-title":"Nutr Cancer"},{"issue":"7","key":"10.1016\/j.clnesp.2024.10.162_bib13","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1007\/s00595-021-02256-y","article-title":"The impact of the preoperative hand grip strength on the long-term outcomes after gastrectomy for advanced gastric cancer","volume":"51","author":"Matsui","year":"2021","journal-title":"Surg Today"},{"issue":"4","key":"10.1016\/j.clnesp.2024.10.162_bib14","doi-asserted-by":"crossref","first-page":"1682","DOI":"10.1002\/jcsm.13248","article-title":"Hand grip strength in patients with advanced cancer: a prospective study","volume":"14","author":"Hadzibegovic","year":"2023","journal-title":"J\u00a0Cachexia Sarcopenia Muscle"},{"issue":"4","key":"10.1016\/j.clnesp.2024.10.162_bib15","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1093\/jjco\/hyac199","article-title":"Validation of the QLQ-CAX24 instrument in cervical cancer and its association with cachexia classifications","volume":"53","author":"Luvi\u00e1n-Morales","year":"2023","journal-title":"Jpn J Clin Oncol"},{"issue":"2","key":"10.1016\/j.clnesp.2024.10.162_bib16","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1177\/082585979100700202","article-title":"The Edmonton Symptom Assessment System (ESAS): a simple method for the assessment of palliative care patients","volume":"7","author":"Bruera","year":"1991","journal-title":"J\u00a0Palliat Care"},{"issue":"6","key":"10.1016\/j.clnesp.2024.10.162_bib17","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1016\/j.jpainsymman.2012.06.007","article-title":"Cut points on 0\u201310 numeric rating scales for symptoms included in the Edmonton symptom assessment scale in cancer patients: a systematic review","volume":"45","author":"Oldenmenger","year":"2013","journal-title":"J\u00a0Pain Symptom Manag"},{"issue":"3","key":"10.1016\/j.clnesp.2024.10.162_bib18","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.jamda.2019.12.012","article-title":"Asian working group for sarcopenia: 2019 consensus update on sarcopenia diagnosis and treatment","volume":"21","author":"Chen","year":"2020","journal-title":"J\u00a0Am Med Dir Assoc"},{"issue":"6","key":"10.1016\/j.clnesp.2024.10.162_bib19","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1016\/j.clnu.2008.06.013","article-title":"Cachexia: a new definition","volume":"27","author":"Evans","year":"2008","journal-title":"Clin Nutr"},{"issue":"3","key":"10.1016\/j.clnesp.2024.10.162_bib20","doi-asserted-by":"crossref","DOI":"10.1093\/ageing\/afae052","article-title":"The conceptual definition of sarcopenia: delphi consensus from the global leadership initiative in sarcopenia (GLIS)","volume":"53","author":"Kirk","year":"2024","journal-title":"Age Ageing"},{"issue":"12","key":"10.1016\/j.clnesp.2024.10.162_bib21","doi-asserted-by":"crossref","first-page":"3261","DOI":"10.1007\/s00520-013-1894-4","article-title":"Handgrip strength predicts survival and is associated with markers of clinical and functional outcomes in advanced cancer patients","volume":"21","author":"Kilgour","year":"2013","journal-title":"Support Care Cancer"},{"issue":"1","key":"10.1016\/j.clnesp.2024.10.162_bib22","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1007\/s00520-018-4320-0","article-title":"Handgrip fatiguing exercise can provide objective assessment of cancer-related fatigue: a pilot study","volume":"27","author":"Veni","year":"2019","journal-title":"Support Care Cancer"}],"container-title":["Clinical Nutrition ESPEN"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405457724015006?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405457724015006?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,2]],"date-time":"2024-12-02T12:45:00Z","timestamp":1733143500000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2405457724015006"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":22,"alternative-id":["S2405457724015006"],"URL":"https:\/\/doi.org\/10.1016\/j.clnesp.2024.10.162","relation":{},"ISSN":["2405-4577"],"issn-type":[{"value":"2405-4577","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Low handgrip strength as a marker of severity in the diagnostic criteria for cancer cachexia","name":"articletitle","label":"Article Title"},{"value":"Clinical Nutrition ESPEN","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clnesp.2024.10.162","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}