{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T08:54:07Z","timestamp":1783673647550,"version":"3.55.0"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100007219","name":"Natural Science Foundation of Shanghai Municipality","doi-asserted-by":"publisher","award":["22ZR1411000"],"award-info":[{"award-number":["22ZR1411000"]}],"id":[{"id":"10.13039\/100007219","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003392","name":"Natural Science Foundation of Fujian Province","doi-asserted-by":"publisher","award":["2022J011415"],"award-info":[{"award-number":["2022J011415"]}],"id":[{"id":"10.13039\/501100003392","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82272921"],"award-info":[{"award-number":["82272921"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82373412"],"award-info":[{"award-number":["82373412"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","clinicalnutritionespen.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Nutrition ESPEN"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1016\/j.clnesp.2025.102901","type":"journal-article","created":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T07:49:56Z","timestamp":1768031396000},"page":"102901","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Association of adipose tissue activity in cervical regions with weight loss and prognostic survival in gastric cancer patients"],"prefix":"10.1016","volume":"72","author":[{"given":"Jun","family":"Han","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diya","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qifeng","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiulei","family":"Xi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanjun","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongyan","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guohao","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.clnesp.2025.102901_bib1","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/S1470-2045(10)70218-7","article-title":"Definition and classification of cancer cachexia: an international consensus","volume":"12","author":"Fearon K, Strasser F, Anker SD, Bosaeus I, Bruera E, Fainsinger RL","year":"2011","journal-title":"Lancet Oncol"},{"issue":"6","key":"10.1016\/j.clnesp.2025.102901_bib2","doi-asserted-by":"crossref","first-page":"1980","DOI":"10.3390\/nu13061980","article-title":"The spectrum of malnutrition\/cachexia\/sarcopenia in oncology according to different cancer types and settings: a narrative review","volume":"13","author":"Bossi","year":"2021","journal-title":"Nutrients"},{"key":"10.1016\/j.clnesp.2025.102901_bib3","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.coph.2015.04.003","article-title":"Cachexia and sarcopenia: mechanisms and potential targets for intervention","volume":"22","author":"Argil\u00e9s","year":"2015","journal-title":"Curr Opin Pharmacol"},{"key":"10.1016\/j.clnesp.2025.102901_bib4","doi-asserted-by":"crossref","DOI":"10.1038\/nrdp.2017.105","article-title":"Cancer-associated cachexia","volume":"4","author":"Baracos","year":"2018","journal-title":"Nat Rev Dis Primers"},{"issue":"2","key":"10.1016\/j.clnesp.2025.102901_bib5","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1007\/s13539-012-0087-1","article-title":"Cancer cachexia: impact, mechanisms and emerging treatments","volume":"4","author":"Vaughan","year":"2013","journal-title":"J Cachexia Sarcopenia Muscle"},{"key":"10.1016\/j.clnesp.2025.102901_bib6","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2022.848394","article-title":"Metabolic reprogramming in adipose tissue during cancer cachexia","volume":"12","author":"Weber","year":"2022","journal-title":"Front Oncol"},{"issue":"7","key":"10.1016\/j.clnesp.2025.102901_bib7","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.2337\/db09-0530","article-title":"High incidence of metabolically active brown adipose tissue in healthy adult humans: effects of cold exposure and adiposity","volume":"58","author":"Saito","year":"2009","journal-title":"Diabetes"},{"issue":"15","key":"10.1016\/j.clnesp.2025.102901_bib8","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1056\/NEJMoa0810780","article-title":"Identification and importance of brown adipose tissue in adult humans","volume":"360","author":"Cypess","year":"2009","journal-title":"N Engl J Med"},{"issue":"15","key":"10.1016\/j.clnesp.2025.102901_bib9","doi-asserted-by":"crossref","first-page":"1518","DOI":"10.1056\/NEJMoa0808949","article-title":"Functional brown adipose tissue in healthy adults","volume":"360","author":"Virtanen","year":"2009","journal-title":"N Engl J Med"},{"issue":"2","key":"10.1016\/j.clnesp.2025.102901_bib10","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0149458","article-title":"Anatomical grading for metabolic activity of brown adipose tissue","volume":"11","author":"Becker","year":"2016","journal-title":"PLoS One"},{"issue":"32","key":"10.1016\/j.clnesp.2025.102901_bib11","doi-asserted-by":"crossref","first-page":"8649","DOI":"10.1073\/pnas.1705287114","article-title":"Mapping of human brown adipose tissue in lean and obese young men","volume":"114","author":"Leitner","year":"2017","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.clnesp.2025.102901_bib12","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.semcdb.2015.10.039","article-title":"Lipolytic and thermogenic depletion of adipose tissue in cancer cachexia","volume":"54","author":"Tsoli","year":"2016","journal-title":"Semin Cell Dev Biol"},{"issue":"3","key":"10.1016\/j.clnesp.2025.102901_bib13","doi-asserted-by":"crossref","first-page":"699","DOI":"10.2337\/diabetes.55.03.06.db05-0841","article-title":"Overexpression of suppressor of cytokine signaling 3 in adipose tissue causes local but not systemic insulin resistance","volume":"55","author":"Shi","year":"2006","journal-title":"Diabetes"},{"issue":"9","key":"10.1016\/j.clnesp.2025.102901_bib14","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1093\/qjmed\/hcy184","article-title":"18F-FDG-PET\/CT scanning-clinical usefulness beyond cancer","volume":"111","author":"Donnelly","year":"2018","journal-title":"QJM"},{"issue":"2","key":"10.1016\/j.clnesp.2025.102901_bib15","doi-asserted-by":"crossref","first-page":"E444","DOI":"10.1152\/ajpendo.00691.2006","article-title":"Unexpected evidence for active brown adipose tissue in adult humans","volume":"293","author":"Nedergaard","year":"2007","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.clnesp.2025.102901_bib16","doi-asserted-by":"crossref","unstructured":"U Din M, Raiko J, Saari T, Kudomi N, Tolvanen T, Oikonen V, et al. Human brown adipose tissue [(15)O] O2 PET imaging in the presence and absence of cold stimulus. Eur J Nucl Med Mol Imag 2016;43(10):1878\u20131886.","DOI":"10.1007\/s00259-016-3364-y"},{"issue":"2","key":"10.1016\/j.clnesp.2025.102901_bib17","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.cmet.2011.06.012","article-title":"Different metabolic responses of human brown adipose tissue to activation by cold and insulin","volume":"14","author":"Orava","year":"2011","journal-title":"Cell Metab"},{"issue":"3","key":"10.1016\/j.clnesp.2025.102901_bib18","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1007\/s00256-018-3046-x","article-title":"Preliminary investigation of brown adipose tissue assessed by PET\/CT and cancer activity","volume":"48","author":"Bos","year":"2019","journal-title":"Skelet Radiol"},{"issue":"7","key":"10.1016\/j.clnesp.2025.102901_bib19","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.2967\/jnumed.106.035915","article-title":"Brown fat imaging with (18)F-6-fluorodopamine PET\/CT, (18)F-FDG PET\/CT, and (123) I-MIBG SPECT: a study of patients being evaluated for pheochromocytoma","volume":"48","author":"Hadi","year":"2007","journal-title":"J Nucl Med"},{"issue":"2","key":"10.1016\/j.clnesp.2025.102901_bib20","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.cmet.2016.07.014","article-title":"Brown adipose reporting criteria in imaging STudies (BARCIST 1.0): recommendations for standardized FDG-PET\/CT experiments in humans","volume":"24","author":"Chen","year":"2016","journal-title":"Cell Metab"},{"issue":"10","key":"10.1016\/j.clnesp.2025.102901_bib21","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.2165\/00003088-200544100-00004","article-title":"Quantification of lean bodyweight","volume":"44","author":"Janmahasatian","year":"2005","journal-title":"Clin Pharmacokinet"},{"issue":"1","key":"10.1016\/j.clnesp.2025.102901_bib22","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1038\/s41591-020-1126-7","article-title":"Brown adipose tissue is associated with cardiometabolic health","volume":"27","author":"Becher T, Palanisamy S, Kramer DJ, Eljalby M, Marx SJ, Wibmer AG","year":"2021","journal-title":"Nat Med"},{"issue":"2","key":"10.1016\/j.clnesp.2025.102901_bib23","doi-asserted-by":"crossref","first-page":"E144","DOI":"10.1152\/ajpendo.00187.2022","article-title":"Brown adipose tissue is not associated with cachexia or increased mortality in a retrospective study of patients with cancer","volume":"324","author":"Eljalby","year":"2023","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.clnesp.2025.102901_bib24","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/j.clnu.2024.12.028","article-title":"Brown adipose tissue is associated with reduced weight loss and risk of cancer cachexia: a retrospective cohort study","volume":"45","author":"Panagiotou","year":"2025","journal-title":"Clin Nutr"},{"issue":"10","key":"10.1016\/j.clnesp.2025.102901_bib25","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0239990","article-title":"Brown fat does not cause cachexia in cancer patients: a large retrospective longitudinal FDG-PET\/CT cohort study","volume":"15","author":"Becker","year":"2020","journal-title":"PLoS One"},{"key":"10.1016\/j.clnesp.2025.102901_bib26","doi-asserted-by":"crossref","first-page":"6775","DOI":"10.2147\/CMAR.S318728","article-title":"One-year mortality in patients with cancer cachexia: association with albumin and total protein","volume":"13","author":"Liu","year":"2021","journal-title":"Cancer Manag Res"},{"issue":"1","key":"10.1016\/j.clnesp.2025.102901_bib27","doi-asserted-by":"crossref","first-page":"7647","DOI":"10.1038\/s41598-022-11736-1","article-title":"Prognostic significance of cachexia index in patients with advanced hepatocellular carcinoma treated with systemic chemotherapy","volume":"12","author":"Goh MJ, Kang W, Jeong WK, Sinn DH, Gwak GY, Paik YH","year":"2022","journal-title":"Sci Rep"},{"issue":"11","key":"10.1016\/j.clnesp.2025.102901_bib28","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1038\/nrc3829","article-title":"Cancer cachexia: understanding the molecular basis","volume":"14","author":"Argil\u00e9s","year":"2014","journal-title":"Nat Rev Cancer"},{"issue":"1","key":"10.1016\/j.clnesp.2025.102901_bib29","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1146\/annurev-nutr-062122-015646","article-title":"Nutritional Mechanisms of Cancer Cachexia","volume":"44","author":"Compton","year":"2024","journal-title":"Annu Rev Nutr"},{"issue":"1","key":"10.1016\/j.clnesp.2025.102901_bib30","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0014-5793(97)00671-6","article-title":"beta-Adrenergic stimulation of interleukin-1alpha and interleukin-6 expression in mouse brown adipocytes","volume":"411","author":"Bur\u00fdsek","year":"1997","journal-title":"FEBS Lett"}],"container-title":["Clinical Nutrition ESPEN"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405457725032140?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405457725032140?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T01:56:53Z","timestamp":1774058213000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2405457725032140"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":30,"alternative-id":["S2405457725032140"],"URL":"https:\/\/doi.org\/10.1016\/j.clnesp.2025.102901","relation":{},"ISSN":["2405-4577"],"issn-type":[{"value":"2405-4577","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association of adipose tissue activity in cervical regions with weight loss and prognostic survival in gastric cancer patients","name":"articletitle","label":"Article Title"},{"value":"Clinical Nutrition ESPEN","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clnesp.2025.102901","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Published by Elsevier Ltd on behalf of European Society for Clinical Nutrition and Metabolism.","name":"copyright","label":"Copyright"}],"article-number":"102901"}}