{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T20:11:39Z","timestamp":1790021499765,"version":"4.0.1"},"reference-count":25,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100022831","name":"University of Health Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100022831","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","clinicalnutritionespen.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Nutrition ESPEN"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.clnesp.2026.103592","type":"journal-article","created":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T06:42:23Z","timestamp":1783752143000},"page":"103592","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Assessment of fecal Elastase-1 and nutritional status in dementia"],"prefix":"10.1016","volume":"75","author":[{"given":"Egecan","family":"Kay\u0131k\u00e7\u0131","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0434-4807","authenticated-orcid":false,"given":"Hakan","family":"Demirci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nil\u00fcfer","family":"B\u00fcy\u00fckkoyuncu Pekel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emre","family":"Yal\u00e7\u0131nta\u015f","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Demet","family":"Y\u0131ld\u0131z","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ersin","family":"Budak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emine Rabia","family":"Ko\u00e7","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.clnesp.2026.103592_bib1","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/S0140-6736(20)30367-6","article-title":"Dementia prevention, intervention, and care: 2020 report of the Lancet Commission","volume":"396","author":"Livingston","year":"2020","journal-title":"Lancet"},{"key":"10.1016\/j.clnesp.2026.103592_bib2","series-title":"Global status report on the public health response to dementia","year":"2021"},{"key":"10.1016\/j.clnesp.2026.103592_bib3","doi-asserted-by":"crossref","first-page":"1599","DOI":"10.1016\/j.clnu.2024.04.039","article-title":"ESPEN guideline on nutrition and hydration in dementia: update 2024","volume":"43","author":"Volkert","year":"2024","journal-title":"Clin Nutr"},{"key":"10.1016\/j.clnesp.2026.103592_bib4","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1007\/s00391-015-0891-2","article-title":"Weight loss and undernutrition in community-dwelling patients with Alzheimer\u2019s dementia: from population-based studies to clinical management","volume":"48","author":"Droogsma","year":"2015","journal-title":"Z Gerontol Geriatr"},{"key":"10.1016\/j.clnesp.2026.103592_bib5","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1007\/s12603-012-0052-x","article-title":"Nutritional predictors of cognitive impairment severity in demented elderly patients: the key role of BMI","volume":"16","author":"Coin","year":"2012","journal-title":"J Nutr Health Aging"},{"key":"10.1016\/j.clnesp.2026.103592_bib6","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1007\/s12603-012-0401-9","article-title":"Malnutrition in community-dwelling adults with dementia (NutriAlz Trial)","volume":"17","author":"Roque","year":"2013","journal-title":"J Nutr Health Aging"},{"key":"10.1016\/j.clnesp.2026.103592_bib7","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1093\/ageing\/afi023","article-title":"Nutritional and cognitive relationships and long-term mortality in patients with various dementia disorders","volume":"34","author":"Fax\u00e9n-Irving","year":"2005","journal-title":"Age Ageing"},{"key":"10.1016\/j.clnesp.2026.103592_bib8","first-page":"466","article-title":"The Mini Nutritional Assessment (MNA) review of the literature\u2014What does it tell us?","volume":"10","author":"Guigoz","year":"2006","journal-title":"J Nutr Health Aging"},{"key":"10.1016\/j.clnesp.2026.103592_bib9","doi-asserted-by":"crossref","first-page":"637S","DOI":"10.1093\/ajcn\/71.2.637s","article-title":"Weight loss in Alzheimer disease","volume":"71","author":"Gillette-Guyonnet","year":"2000","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.clnesp.2026.103592_bib10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.clnu.2018.08.002","article-title":"GLIM criteria for the diagnosis of malnutrition \u2013 a consensus report from the global clinical nutrition community","volume":"38","author":"Cederholm","year":"2019","journal-title":"Clin Nutr"},{"key":"10.1016\/j.clnesp.2026.103592_bib11","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/j.clnu.2017.09.003","article-title":"ESPEN guideline clinical nutrition in neurology","volume":"37","author":"Burgos","year":"2018","journal-title":"Clin Nutr"},{"key":"10.1016\/j.clnesp.2026.103592_bib12","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1016\/j.clnu.2020.01.004","article-title":"ESPEN guideline on clinical nutrition in acute and chronic pancreatitis","volume":"39","author":"Arvanitakis","year":"2020","journal-title":"Clin Nutr"},{"issue":"Suppl 6","key":"10.1016\/j.clnesp.2026.103592_bib13","doi-asserted-by":"crossref","first-page":"vi1","DOI":"10.1136\/gut.2005.065946","article-title":"Human pancreatic exocrine response to nutrients in health and disease","volume":"54","author":"Keller","year":"2005","journal-title":"Gut"},{"key":"10.1016\/j.clnesp.2026.103592_bib14","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1097\/MOG.0000000000000459","article-title":"Diagnosis and treatment of pancreatic exocrine insufficiency","volume":"34","author":"Dom\u00ednguez-Mu\u00f1oz","year":"2018","journal-title":"Curr Opin Gastroenterol"},{"issue":"1","key":"10.1016\/j.clnesp.2026.103592_bib15","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1002\/ueg2.12674","article-title":"European guidelines for the diagnosis and treatment of pancreatic exocrine insufficiency: UEG, EPC, EDS, ESPEN, ESPGHAN, ESDO, and ESPCG evidence-based recommendations","volume":"13","author":"Dominguez-Mu\u00f1oz","year":"2025","journal-title":"United European Gastroenterol J"},{"key":"10.1016\/j.clnesp.2026.103592_bib16","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1016\/j.cgh.2018.01.027","article-title":"Diagnostic performance of measurement of fecal elastase-1 in detection of exocrine pancreatic insufficiency: systematic review and meta-analysis","volume":"16","author":"Vanga","year":"2018","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.clnesp.2026.103592_bib17","first-page":"41","article-title":"Gastrointestinal diseases in the elderly","volume":"6","author":"Holt","year":"2003","journal-title":"Curr Opin Clin Nutr Metab Care"},{"key":"10.1016\/j.clnesp.2026.103592_bib18","doi-asserted-by":"crossref","first-page":"368","DOI":"10.5505\/amj.2025.78476","article-title":"Exocrine pancreatic function in erectile dysfunction: a prospective study based on fecal elastase measurement","volume":"3","author":"Sat\u0131r","year":"2025","journal-title":"Ankara Med J"},{"key":"10.1016\/j.clnesp.2026.103592_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejogrb.2026.115078","article-title":"Maternal fecal elastase-1 levels are lower in pregnancies with intrauterine growth restriction","volume":"321","author":"Gergil","year":"2026","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.clnesp.2026.103592_bib20","series-title":"Diagnostic and statistical manual of mental disorders","year":"2013"},{"key":"10.1016\/j.clnesp.2026.103592_bib21","first-page":"273","article-title":"Reliability and validity of the standardized Mini Mental State Examination in the diagnosis of mild dementia in Turkish population","volume":"13","author":"G\u00fcngen","year":"2002","journal-title":"Turk Psikiyatri Derg"},{"key":"10.1016\/j.clnesp.2026.103592_bib22","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1097\/01.JGP.0000192478.82189.a8","article-title":"Mapping scores onto stages: Mini-Mental State Examination and Clinical Dementia Rating","volume":"14","author":"Perneczky","year":"2006","journal-title":"Am J Geriatr Psychiatry"},{"key":"10.1016\/j.clnesp.2026.103592_bib23","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1136\/gut.39.4.580","article-title":"Faecal elastase 1: a novel, highly sensitive, and specific tubeless pancreatic function test","volume":"39","author":"L\u00f6ser","year":"1996","journal-title":"Gut"},{"key":"10.1016\/j.clnesp.2026.103592_bib24","doi-asserted-by":"crossref","first-page":"1430","DOI":"10.1016\/j.jamda.2020.06.051","article-title":"The relationship between dementia subtypes and nutritional parameters in older adults","volume":"21","author":"Soysal","year":"2020","journal-title":"J Am Med Dir Assoc"},{"issue":"22","key":"10.1016\/j.clnesp.2026.103592_bib25","doi-asserted-by":"crossref","first-page":"3127","DOI":"10.1002\/1097-0258(20001130)19:22<3127::AID-SIM784>3.0.CO;2-M","article-title":"A simple method for converting an odds ratio to effect size for use in meta-analysis","volume":"19","author":"Chinn","year":"2000","journal-title":"Stat Med"}],"container-title":["Clinical Nutrition ESPEN"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405457726006893?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405457726006893?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T19:32:48Z","timestamp":1790019168000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2405457726006893"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":25,"alternative-id":["S2405457726006893"],"URL":"https:\/\/doi.org\/10.1016\/j.clnesp.2026.103592","relation":{},"ISSN":["2405-4577"],"issn-type":[{"value":"2405-4577","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Assessment of fecal Elastase-1 and nutritional status in dementia","name":"articletitle","label":"Article Title"},{"value":"Clinical Nutrition ESPEN","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clnesp.2026.103592","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"103592"}}