{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T20:07:29Z","timestamp":1790021249270,"version":"4.0.1"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T00:00:00Z","timestamp":1787529600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","clinicalnutritionespen.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Nutrition ESPEN"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.clnesp.2026.105057","type":"journal-article","created":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T07:01:32Z","timestamp":1787641292000},"page":"105057","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Mediterranean diet and skeletal health: Mechanistic pathways and implications for osteoporosis"],"prefix":"10.1016","volume":"75","author":[{"given":"I.","family":"Branco-Rodrigues","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1375-8067","authenticated-orcid":false,"given":"J.","family":"Costa-Rodrigues","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"14","key":"10.1016\/j.clnesp.2026.105057_bib1","doi-asserted-by":"crossref","DOI":"10.3390\/nu15143224","article-title":"The influence of the mediterranean dietary pattern on osteoporosis and sarcopenia","volume":"15","author":"Andreo-Lopez","year":"2023","journal-title":"Nutrients"},{"issue":"4","key":"10.1016\/j.clnesp.2026.105057_bib2","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2025.3710","article-title":"Mediterranean diet, physical activity, and bone health in older adults: a secondary analysis of a randomized clinical trial","volume":"8","author":"Vazquez-Lorente","year":"2025","journal-title":"JAMA Netw Open"},{"issue":"1","key":"10.1016\/j.clnesp.2026.105057_bib3","doi-asserted-by":"crossref","DOI":"10.3390\/diseases11010029","article-title":"Vitamin D and calcium in osteoporosis, and the role of bone turnover markers: a narrative review of recent data from RCTs","volume":"11","author":"Voulgaridou","year":"2023","journal-title":"Diseases"},{"issue":"14","key":"10.1016\/j.clnesp.2026.105057_bib4","doi-asserted-by":"crossref","DOI":"10.3390\/nu16142289","article-title":"The effects of different dietary patterns on bone health","volume":"16","author":"Liu","year":"2024","journal-title":"Nutrients"},{"issue":"6","key":"10.1016\/j.clnesp.2026.105057_bib5","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1093\/nutrit\/nuae141","article-title":"Mediterranean diet and risk of hip fracture: a systematic review and dose-response meta-analysis","volume":"83","author":"Fa-Binefa","year":"2025","journal-title":"Nutr Rev"},{"issue":"7","key":"10.1016\/j.clnesp.2026.105057_bib6","doi-asserted-by":"crossref","DOI":"10.3390\/nu12071986","article-title":"Nutrients and dietary patterns related to osteoporosis","volume":"12","author":"Munoz-Garach","year":"2020","journal-title":"Nutrients"},{"issue":"3","key":"10.1016\/j.clnesp.2026.105057_bib7","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1007\/s00394-021-02751-5","article-title":"Inflammatory potential of diet and bone mineral density in a senior mediterranean population: a cross-sectional analysis of PREDIMED-plus study","volume":"61","author":"Garcia-Gavilan","year":"2022","journal-title":"Eur J Nutr"},{"key":"10.1016\/j.clnesp.2026.105057_bib8","doi-asserted-by":"crossref","DOI":"10.3389\/fnut.2025.1613065","article-title":"Study on the correlation between dietary patterns and bone health among rural elderly people in qingdao","volume":"12","author":"Chang","year":"2025","journal-title":"Front Nutr"},{"issue":"1","key":"10.1016\/j.clnesp.2026.105057_bib9","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1038\/s44324-024-00010-9","article-title":"Bone metabolism - an underappreciated player","volume":"2","author":"Choi","year":"2024","journal-title":"npj metab health dis"},{"issue":"24","key":"10.1016\/j.clnesp.2026.105057_bib10","doi-asserted-by":"crossref","DOI":"10.3390\/nu17243845","article-title":"Impact of dietary patterns on skeletal health: a systematic review and meta-analysis of bone mineral density, fracture, bone turnover markers, and nutritional status","volume":"17","author":"Mullath Ullas","year":"2025","journal-title":"Nutrients"},{"issue":"2","key":"10.1016\/j.clnesp.2026.105057_bib11","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.jocd.2021.08.001","article-title":"Bending resistance at hip and fractures risk in postmenopausal women independent of bone mineral density","volume":"25","author":"Mazza","year":"2022","journal-title":"J Clin Densitom"},{"issue":"19","key":"10.1016\/j.clnesp.2026.105057_bib12","doi-asserted-by":"crossref","DOI":"10.3390\/nu15194255","article-title":"Association of alternative dietary patterns with osteoporosis and fracture risk in older people: a scoping review","volume":"15","author":"Chen","year":"2023","journal-title":"Nutrients"},{"key":"10.1016\/j.clnesp.2026.105057_bib13","doi-asserted-by":"crossref","DOI":"10.3389\/fnut.2025.1609442","article-title":"The impact of high-quality dietary patterns on the prevention of osteoporosis: a meta-analysis of observational studies","volume":"12","author":"Sui","year":"2025","journal-title":"Front Nutr"},{"issue":"1","key":"10.1016\/j.clnesp.2026.105057_bib14","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1186\/s12877-025-05843-7","article-title":"Osteoporosis risk and its association with all-cause and cause-specific mortality among the elderly: a 16-year nationwide cohort study","volume":"25","author":"Pan","year":"2025","journal-title":"BMC Geriatr"},{"issue":"3","key":"10.1016\/j.clnesp.2026.105057_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbspin.2022.105521","article-title":"Dietary recommendations in the prevention and treatment of osteoporosis","volume":"90","author":"Biver","year":"2023","journal-title":"Jt Bone Spine"},{"issue":"1","key":"10.1016\/j.clnesp.2026.105057_bib16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3945\/an.116.013326","article-title":"Current evidence on the association of dietary patterns and bone health: a scoping review","volume":"8","author":"Movassagh","year":"2017","journal-title":"Adv Nutr"},{"issue":"12","key":"10.1016\/j.clnesp.2026.105057_bib17","doi-asserted-by":"crossref","DOI":"10.3390\/nu10121922","article-title":"Dietary patterns, bone mineral density, and risk of fractures: a systematic review and meta-analysis","volume":"10","author":"Denova-Gutierrez","year":"2018","journal-title":"Nutrients"},{"issue":"4","key":"10.1016\/j.clnesp.2026.105057_bib18","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.1007\/s00394-017-1432-0","article-title":"Adherence to a Mediterranean-style diet and incident fractures: pooled analysis of observational evidence","volume":"57","author":"Kunutsor","year":"2018","journal-title":"Eur J Nutr"},{"issue":"6","key":"10.1016\/j.clnesp.2026.105057_bib19","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1007\/s11914-024-00892-0","article-title":"Nutrition and osteoporosis prevention","volume":"22","author":"Rizzoli","year":"2024","journal-title":"Curr Osteoporos Rep"},{"issue":"4","key":"10.1016\/j.clnesp.2026.105057_bib20","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1007\/s11914-015-0272-1","article-title":"Dietary approaches for bone health: lessons from the framingham osteoporosis study","volume":"13","author":"Sahni","year":"2015","journal-title":"Curr Osteoporos Rep"},{"issue":"3","key":"10.1016\/j.clnesp.2026.105057_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.numecd.2025.104429","article-title":"Dietary habits and fragility fractures","volume":"36","author":"Abate","year":"2026","journal-title":"Nutr Metabol Cardiovasc Dis"},{"issue":"2","key":"10.1016\/j.clnesp.2026.105057_bib22","doi-asserted-by":"crossref","first-page":"110","DOI":"10.2174\/1874609814666211005101730","article-title":"Adequate intake and supplementation of B vitamins, in particular folic acid, can play a protective role in bone health","volume":"15","author":"Rondanelli","year":"2022","journal-title":"Curr Aging Sci"},{"issue":"1","key":"10.1016\/j.clnesp.2026.105057_bib23","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-023-50423-7","article-title":"The association between dietary approaches to stop hypertension diet and bone mineral density in US adults: evidence from the national health and nutrition examination survey (2011-2018)","volume":"13","author":"Zhai","year":"2023","journal-title":"Sci Rep"},{"key":"10.1016\/j.clnesp.2026.105057_bib24","article-title":"The multi-faceted nature of age-associated osteoporosis","volume":"20","author":"Smit","year":"2024","journal-title":"BoneKEy Rep"},{"issue":"2","key":"10.1016\/j.clnesp.2026.105057_bib25","article-title":"Review of osteoporotic fractures: occurrence, prevention, and consequences","volume":"60","author":"Elias","year":"2025","journal-title":"Rev Bras Ortop (Sao Paulo)"},{"issue":"5","key":"10.1016\/j.clnesp.2026.105057_bib26","first-page":"989","article-title":"Adherence to mediterranean diet and bone health","volume":"29","author":"Romero Perez","year":"2014","journal-title":"Nutr Hosp"},{"issue":"3","key":"10.1016\/j.clnesp.2026.105057_bib27","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1007\/s11914-020-00573-8","article-title":"The role of diet in osteoporotic fracture healing: a systematic review","volume":"18","author":"Chiavarini","year":"2020","journal-title":"Curr Osteoporos Rep"},{"key":"10.1016\/j.clnesp.2026.105057_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.nut.2025.112950","article-title":"Diet guideline, efficacy of mediterranean diet in musculoskeletal disorders: a systematic review and meta-analysis for primary and tertiary prevention featured in the Italian national guidelines \"La Dieta Mediterranea\"","volume":"142","author":"Limongi","year":"2026","journal-title":"Nutrition"},{"issue":"19","key":"10.1016\/j.clnesp.2026.105057_bib29","doi-asserted-by":"crossref","DOI":"10.1096\/fj.202502040R","article-title":"The impact of dietary patterns on the human gut microbiome and its health significance: a review","volume":"39","author":"Muigano","year":"2025","journal-title":"FASEB J"},{"issue":"4","key":"10.1016\/j.clnesp.2026.105057_bib30","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1002\/jbmr.4231","article-title":"Skeletal protection and promotion of microbiome diversity by dietary boosting of the endogenous antioxidant response","volume":"36","author":"Sato","year":"2021","journal-title":"J Bone Miner Res"},{"issue":"6","key":"10.1016\/j.clnesp.2026.105057_bib31","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.3390\/biom13061006","article-title":"The role of trace elements and minerals in osteoporosis: a review of epidemiological and laboratory findings","volume":"13","author":"Skalny","year":"2023","journal-title":"Biomolecules"},{"key":"10.1016\/j.clnesp.2026.105057_bib32","doi-asserted-by":"crossref","DOI":"10.3389\/fnut.2024.1389638","article-title":"Gut microbes differ in postmenopausal women responding to prunes to maintain hip bone mineral density","volume":"11","author":"Simpson","year":"2024","journal-title":"Front Nutr"},{"issue":"3","key":"10.1016\/j.clnesp.2026.105057_bib33","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1007\/s00223-021-00924-2","article-title":"Role of the microbiome in regulating bone metabolism and susceptibility to osteoporosis","volume":"110","author":"Cronin","year":"2022","journal-title":"Calcif Tissue Int"},{"issue":"12","key":"10.1016\/j.clnesp.2026.105057_bib34","doi-asserted-by":"crossref","first-page":"3031","DOI":"10.1007\/s00198-013-2421-7","article-title":"Adherence to a mediterranean diet and risk of fractures in French older persons","volume":"24","author":"Feart","year":"2013","journal-title":"Osteoporos Int"},{"key":"10.1016\/j.clnesp.2026.105057_bib35","article-title":"The effects of popular diets on bone health in the past decade: a narrative review","volume":"14","author":"Peng","year":"2023","journal-title":"Front Endocrinol"},{"issue":"24","key":"10.1016\/j.clnesp.2026.105057_bib36","doi-asserted-by":"crossref","DOI":"10.3390\/nu17243935","article-title":"Bone turnover markers (CTX and P1NP) following low-carbohydrate and mediterranean diet interventions in adolescents and young adults with type 1 diabetes","volume":"17","author":"Levran","year":"2025","journal-title":"Nutrients"},{"issue":"7","key":"10.1016\/j.clnesp.2026.105057_bib37","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1007\/s00198-018-4517-6","article-title":"Mediterranean diet and hip fracture incidence among older adults: the CHANCES project","volume":"29","author":"Benetou","year":"2018","journal-title":"Osteoporos Int"},{"issue":"10","key":"10.1016\/j.clnesp.2026.105057_bib38","doi-asserted-by":"crossref","DOI":"10.3390\/nu11102508","article-title":"Adherence to the mediterranean diet and bone fracture risk in middle-aged women: a case control study","volume":"11","author":"Palomeras-Vilches","year":"2019","journal-title":"Nutrients"},{"key":"10.1016\/j.clnesp.2026.105057_bib39","doi-asserted-by":"crossref","DOI":"10.3389\/fnut.2025.1629806","article-title":"Evaluation of a 12-week mediterranean diet-based nutritional and educational programme for breast cancer survivors: impact on BMI, fatigue, dietary adherence, and menopausal symptoms","volume":"12","author":"White","year":"2025","journal-title":"Front Nutr"},{"issue":"15","key":"10.1016\/j.clnesp.2026.105057_bib40","doi-asserted-by":"crossref","first-page":"2735","DOI":"10.1017\/S1368980017001793","article-title":"Associations of Baltic sea and mediterranean dietary patterns with bone mineral density in elderly women","volume":"20","author":"Erkkila","year":"2017","journal-title":"Public Health Nutr"}],"container-title":["Clinical Nutrition ESPEN"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405457726021546?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405457726021546?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T19:23:55Z","timestamp":1790018635000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2405457726021546"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":40,"alternative-id":["S2405457726021546"],"URL":"https:\/\/doi.org\/10.1016\/j.clnesp.2026.105057","relation":{},"ISSN":["2405-4577"],"issn-type":[{"value":"2405-4577","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mediterranean diet and skeletal health: Mechanistic pathways and implications for osteoporosis","name":"articletitle","label":"Article Title"},{"value":"Clinical Nutrition ESPEN","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clnesp.2026.105057","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Ltd on behalf of European Society for Clinical Nutrition and Metabolism.","name":"copyright","label":"Copyright"}],"article-number":"105057"}}