{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T09:23:46Z","timestamp":1783070626317,"version":"3.54.6"},"reference-count":33,"publisher":"Elsevier BV","issue":"4","content-domain":{"domain":["journals.elsevierhealth.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Nutrition"],"published-print":{"date-parts":[[2013,8]]},"DOI":"10.1016\/j.clnu.2012.11.013","type":"journal-article","created":{"date-parts":[[2012,11,23]],"date-time":"2012-11-23T08:01:48Z","timestamp":1353657708000},"page":"636-642","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":32,"title":["Effects of fish oil containing eicosapentaenoic acid and docosahexaenoic acid on dystrophic mdx mice"],"prefix":"10.1016","volume":"32","author":[{"given":"Adriana","family":"Fogagnolo Mauricio","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elaine","family":"Minatel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Humberto","family":"Santo Neto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Julia","family":"Marques","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.clnu.2012.11.013_bib1","series-title":"Myology","first-page":"1133","article-title":"Distrophinopathies","author":"Engel","year":"1994"},{"key":"10.1016\/j.clnu.2012.11.013_bib2","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1007\/s00109-003-0484-1","article-title":"Therapeutics for Duchenne muscular dystrophy: current approaches and future directions","volume":"82","author":"Bogdanovich","year":"2004","journal-title":"J\u00a0Mol Med (Berl)"},{"key":"10.1016\/j.clnu.2012.11.013_bib3","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1096\/fj.03-1024com","article-title":"Anti-TNF\u03b1 (Remicade\u00ae) therapy protects dystrophic skeletal muscle from necrosis","volume":"18","author":"Grounds","year":"2004","journal-title":"FASEB J"},{"key":"10.1016\/j.clnu.2012.11.013_bib4","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1111\/j.1440-1681.2006.04394.x","article-title":"Muscle damage in mdx (dystrophic) mice: role of calcium and reactive oxygen species","volume":"33","author":"Whitehead","year":"2006","journal-title":"Clin Exp Pharmacol Physiol"},{"key":"10.1016\/j.clnu.2012.11.013_bib5","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1016\/j.nut.2011.09.013","article-title":"Ascorbic acid protects the diaphragm muscle against myonecrosis in mdx mice","volume":"28","author":"Tonon","year":"2012","journal-title":"Nutrition"},{"key":"10.1016\/j.clnu.2012.11.013_bib6","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1016\/S0960-8966(01)00198-5","article-title":"Do immune cells promote the pathology of dystrophin-deficient myopathies?","volume":"11","author":"Spencer","year":"2001","journal-title":"Neuromuscul Disord"},{"key":"10.1016\/j.clnu.2012.11.013_bib7","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1002\/mus.20150","article-title":"Localization and early time course of TGF-Beta1 mRNA expression in dystrophic muscle","volume":"30","author":"Gosselin","year":"2004","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.clnu.2012.11.013_bib8","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1002\/1097-4598(200009)23:9<1344::AID-MUS4>3.0.CO;2-F","article-title":"A\u00a0multicenter, double-blind, randomized trial of deflazacort versus prednisone in Duchenne muscular dystrophy","volume":"23","author":"Bonifati","year":"2000","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.clnu.2012.11.013_bib9","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1080\/07315724.2002.10719248","article-title":"Omega-3 fatty acids in inflammation and autoimmune diseases","volume":"21","author":"Simopoulos","year":"2002","journal-title":"J\u00a0Am Coll Nutr"},{"key":"10.1016\/j.clnu.2012.11.013_bib10","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1007\/s10067-011-1848-5","article-title":"Omega-3 fatty acids in juvenile idiopathic arthritis: effect on cytokines (IL-1 and TNF-\u03b1), disease activity and response criteria","volume":"31","author":"Gheita","year":"2012","journal-title":"Clin Rheumatol"},{"key":"10.1016\/j.clnu.2012.11.013_bib11","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.cct.2011.09.009","article-title":"The VITamin D and Omega-3 Trial (VITAL): rationale and design of a large randomized controlled trial of vitamin D and marine omega-3 fatty acid supplements for the primary prevention of cancer and cardiovascular disease","volume":"33","author":"Manson","year":"2012","journal-title":"Contemp Clin Trial"},{"key":"10.1016\/j.clnu.2012.11.013_bib12","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.jneuroim.2010.10.032","article-title":"Eicosapentaenoic acid decreases TNF-alpha and protects dystrophic muscles of mdx mice from degeneration","volume":"232","author":"Machado","year":"2011","journal-title":"J\u00a0Neuroimmunol"},{"key":"10.1016\/j.clnu.2012.11.013_bib13","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1124\/jpet.108.148718","article-title":"Eicosapentaenoic acid improves imbalance between vasodilator and vasoconstrictor actions of endothelium-derived factors in mesenteric arteries from rats at chronic stage of type 2 diabetes","volume":"329","author":"Matsumoto","year":"2009","journal-title":"J\u00a0Pharmacol Exp Ther"},{"key":"10.1016\/j.clnu.2012.11.013_bib14","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1002\/mus.21869","article-title":"Prevention of muscle fibrosis and myonecrosis in mdx mice by suramin, a TGF-beta 1 blocker","volume":"43","author":"Taniguti","year":"2011","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.clnu.2012.11.013_bib15","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.expneurol.2009.09.015","article-title":"Flavocoxid\u00a0counteracts muscle necrosis and improves functional properties in mdx mice: a comparison study with methylprednisone","volume":"220","author":"Messina","year":"2009","journal-title":"Exp Neurol"},{"key":"10.1016\/j.clnu.2012.11.013_bib16","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1038\/352536a0","article-title":"The mdx mouse diaphragm reproduces the degenerative changes of Duchenne muscular dystrophy","volume":"352","author":"Stedman","year":"1991","journal-title":"Nature"},{"key":"10.1016\/j.clnu.2012.11.013_bib17","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/S0163-7827(03)00014-6","article-title":"4-Hydroxy-2-nonenal: a product and mediator of oxidative stress","volume":"42","author":"Uchida","year":"2003","journal-title":"Prog Lipid Res"},{"key":"10.1016\/j.clnu.2012.11.013_bib18","article-title":"N-acetylcysteine treatment reduces TNF-alpha levels and myonecrosis in diaphragm muscle of mdx mice","author":"Pinto","year":"2012","journal-title":"Clin Nutr"},{"key":"10.1016\/j.clnu.2012.11.013_bib19","doi-asserted-by":"crossref","first-page":"918","DOI":"10.2353\/ajpath.2006.050673","article-title":"Lipid peroxidation inhibition blunts nuclear factor-kappaB activation, reduces skeletal muscle degeneration, and enhances muscle function in mdx mice","volume":"168","author":"Messina","year":"2006","journal-title":"Am J Pathol"},{"key":"10.1016\/j.clnu.2012.11.013_bib20","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1016\/j.metabol.2011.10.019","article-title":"Fatty acid profile of skeletal muscle phospholipid is altered in mdx mice and predictive of disease markers","volume":"61","author":"Tuazon","year":"2012","journal-title":"Metabolism"},{"key":"10.1016\/j.clnu.2012.11.013_bib21","doi-asserted-by":"crossref","first-page":"1467S","DOI":"10.1093\/ajcn\/83.6.1467S","article-title":"Distribution, interconversion, and dose response of n\u22123 fatty acids in humans","volume":"83","author":"Arterburn","year":"2006","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.clnu.2012.11.013_bib22","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1113\/jphysiol.2005.091694","article-title":"Mechanisms of stretch-induced muscle damage in normal and dystrophic muscle: role of ionic changes","volume":"567","author":"Allen","year":"2005","journal-title":"J\u00a0Physiol"},{"key":"10.1016\/j.clnu.2012.11.013_bib23","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1007\/s10620-010-1400-5","article-title":"Eicosapentaenoic acid attenuates progression of hepatic fibrosis with inhibition of reactive oxygen species production in rats fed methionine- and choline-deficient diet","volume":"56","author":"Kajikawa","year":"2010","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.clnu.2012.11.013_bib24","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/S0022-2275(20)31657-6","article-title":"Partitioning of polyunsaturated fatty acids, which prevent cardiac arrhythmias, into phospholipid cell membranes","volume":"42","author":"Pound","year":"2001","journal-title":"J\u00a0Lipid Res"},{"key":"10.1016\/j.clnu.2012.11.013_bib25","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.pbiomolbio.2005.05.006","article-title":"Dietary long-chain omega-3 fatty acids of marine origin: a comparison of their protective effects on coronary heart disease and breast cancers","volume":"90","author":"Jud\u00e8","year":"2006","journal-title":"Prog Biophys Mol Biol"},{"key":"10.1016\/j.clnu.2012.11.013_bib26","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.plefa.2010.02.002","article-title":"Polyunsaturated docosahexaenoic acid suppresses oxidative stress induce endothelial cell calcium influx by altering lipid composition in membrane caveolar rafts","volume":"83","author":"Ye","year":"2010","journal-title":"Prostaglandins Leukot Essent Fatty Acids"},{"key":"10.1016\/j.clnu.2012.11.013_bib27","doi-asserted-by":"crossref","first-page":"R345","DOI":"10.1152\/ajpregu.00454.2004","article-title":"Inflammatory process in muscle injury and repair","volume":"288","author":"Tidball","year":"2006","journal-title":"Am J Physiol Regul Comp Physiol"},{"key":"10.1016\/j.clnu.2012.11.013_bib28","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/0165-2478(92)90021-F","article-title":"Dietary supplementation with fish oil enhances in\u00a0vivo synthesis of tumor necrosis factor","volume":"34","author":"Chang","year":"1992","journal-title":"Immunol Lett"},{"key":"10.1016\/j.clnu.2012.11.013_bib29","first-page":"1031","article-title":"Fish oil supplementation modulates immune function in healthy infants","volume":"137","author":"Damsgaard","year":"2007","journal-title":"J\u00a0Nutr"},{"key":"10.1016\/j.clnu.2012.11.013_bib30","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1476-511X-7-24","article-title":"The omega-3 fatty acid, eicosapentaenoic acid\u00a0(EPA), prevents the damaging effects of tumor necrosis factor (TNF)-alpha\u00a0during murine skeletal muscle cell differentiation","volume":"7","author":"Magee","year":"2008","journal-title":"Lipids Health Dis"},{"key":"10.1016\/j.clnu.2012.11.013_bib31","doi-asserted-by":"crossref","first-page":"343S","DOI":"10.1093\/ajcn\/71.1.343s","article-title":"Dietary polyunsaturated fatty acids and inflammatory mediator production","volume":"71","author":"James","year":"2000","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.clnu.2012.11.013_bib32","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1042\/BJ20110967","article-title":"Omega-3 docosahexaenoic acid and procyanidins inhibit cyclooxygenase activity and attenuate NF-\u03baB activation through a p105\/p50 regulatory mechanism in macrophage inflammation","volume":"44","author":"Martinez-Micaelo","year":"2012","journal-title":"Biochem J"},{"key":"10.1016\/j.clnu.2012.11.013_bib33","first-page":"550","article-title":"Fatty acids and inflammation: the cutting edge between food and pharma","volume":"668","author":"Calder","year":"2011","journal-title":"Eur J Pharmacol"}],"container-title":["Clinical Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0261561412002610?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0261561412002610?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T01:05:42Z","timestamp":1643677542000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0261561412002610"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,8]]},"references-count":33,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,8]]}},"alternative-id":["S0261561412002610"],"URL":"https:\/\/doi.org\/10.1016\/j.clnu.2012.11.013","relation":{},"ISSN":["0261-5614"],"issn-type":[{"value":"0261-5614","type":"print"}],"subject":[],"published":{"date-parts":[[2013,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of fish oil containing eicosapentaenoic acid and docosahexaenoic acid on dystrophic mdx mice","name":"articletitle","label":"Article Title"},{"value":"Clinical Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clnu.2012.11.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.","name":"copyright","label":"Copyright"}]}}