{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T04:30:53Z","timestamp":1790742653598,"version":"4.1.0"},"reference-count":50,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2015,4,1]],"date-time":"2015-04-01T00:00:00Z","timestamp":1427846400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,8,29]],"date-time":"2014-08-29T00:00:00Z","timestamp":1409270400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":["journals.elsevierhealth.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Nutrition"],"published-print":{"date-parts":[[2015,4]]},"DOI":"10.1016\/j.clnu.2014.08.012","type":"journal-article","created":{"date-parts":[[2014,8,29]],"date-time":"2014-08-29T14:16:26Z","timestamp":1409321786000},"page":"189-194","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":98,"title":["Non coeliac gluten sensitivity \u2013 A new disease with gluten intolerance"],"prefix":"10.1016","volume":"34","author":[{"given":"Gra\u017cyna","family":"Czaja-Bulsa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.clnu.2014.08.012_bib1","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/1741-7015-10-13","article-title":"Spectrum of gluten disorders: consensus on new nomenclature and classification","volume":"10","author":"Sapone","year":"2012","journal-title":"BMC Med"},{"issue":"1 Suppl.","key":"10.1016\/j.clnu.2014.08.012_bib2","doi-asserted-by":"crossref","first-page":"68S","DOI":"10.1177\/0148607111426276","article-title":"Celiac disease, wheat allergy, and gluten sensitivity: when gluten free is not a fad","volume":"36","author":"Pietzak","year":"2012","journal-title":"JPEN J Parenter Eternal Nutr"},{"key":"10.1016\/j.clnu.2014.08.012_bib3","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1038\/ajg.2010.487","article-title":"Gluten causes gastrointestinal symptoms in subjects without celiac disease: a double-blind randomized placebo-controlled trial","volume":"106","author":"Biesiekierski","year":"2011","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.clnu.2014.08.012_bib4","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1136\/gutjnl-2011-301346","article-title":"The Oslo definitions for coeliac disease and related terms","volume":"62","author":"Ludvigsson","year":"2013","journal-title":"Gut"},{"key":"10.1016\/j.clnu.2014.08.012_bib5","doi-asserted-by":"crossref","first-page":"309","DOI":"10.7326\/0003-4819-156-4-201202210-00010","article-title":"Nonceliac gluten sensitivity: sense or sensibility?","volume":"156","author":"Di Sabatino","year":"2012","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.clnu.2014.08.012_bib6","doi-asserted-by":"crossref","first-page":"3839","DOI":"10.3390\/nu5103839","article-title":"Non-celiac gluten sensitivity: the new frontier of gluten related disorders","volume":"5","author":"Catassi","year":"2013","journal-title":"Nutrients"},{"key":"10.1016\/j.clnu.2014.08.012_bib7","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/0016-5085(81)90689-2","article-title":"Gluten sensitive diarrhea without evidence of celiac disease [letter]","volume":"81","author":"Cooper","year":"1981","journal-title":"Gastroenterology"},{"key":"10.1016\/j.clnu.2014.08.012_bib8","doi-asserted-by":"crossref","first-page":"S254","DOI":"10.1016\/S1590-8658(12)60659-8","article-title":"Gluten sensitivity in children: clinical, serological, genetic and histological description of the first pediatric series","volume":"44","author":"Mastrototaro","year":"2012","journal-title":"Dig Liver Dis"},{"key":"10.1016\/j.clnu.2014.08.012_bib9","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1038\/ajg.2009.188","article-title":"Between celiac disease and irritable bowel syndrome: the \u201cno man's land\u201d of gluten sensitivity","volume":"104","author":"Verdu","year":"2009","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.clnu.2014.08.012_bib10","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1159\/000260087","article-title":"Differential mucosal IL-17 expression in two gliadin-induced disorders: gluten sensitivity and the autoimmune enteropathy celiac disease","volume":"152","author":"Sapone","year":"2010","journal-title":"Int Arch Allergy Immunol"},{"key":"10.1016\/j.clnu.2014.08.012_bib11","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1097\/01.meg.0000435546.87251.f7","article-title":"A UK study assessing the population prevalence of self-reported gluten sensitivity and referral characteristics to secondary care","volume":"26","author":"Aziz","year":"2014","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1016\/j.clnu.2014.08.012_bib12","doi-asserted-by":"crossref","DOI":"10.1186\/1741-7015-12-85","article-title":"An Italian prospective multicenter survey on patients suspected of having non-celiac gluten sensitivity","author":"Volta","year":"2014","journal-title":"BMC Med"},{"key":"10.1016\/j.clnu.2014.08.012_bib13","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1053\/gast.2001.29572","article-title":"Celiac disease-like abnormalities in a subgroup of patients with irritable bowel syndrome","volume":"121","author":"Wahnschaffe","year":"2001","journal-title":"Gastroenterology"},{"key":"10.1016\/j.clnu.2014.08.012_bib14","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1016\/j.cgh.2007.03.021","article-title":"Predictors of clinical response to gluten-free diet in patients diagnosed with diarrhea-predominant irritable bowel syndrome","volume":"5","author":"Wahnschaffe","year":"2007","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.clnu.2014.08.012_bib15","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1111\/j.1365-2796.2011.02385.x","article-title":"Coeliac disease and gluten sensitivity","volume":"269","author":"Trankone","year":"2011","journal-title":"J Intern Med"},{"key":"10.1016\/j.clnu.2014.08.012_bib16","article-title":"Clinical, serologic, and histologic features of gluten sensitivity in children","author":"Francavilla","year":"2013","journal-title":"J Pediatr"},{"key":"10.1016\/j.clnu.2014.08.012_bib17","doi-asserted-by":"crossref","first-page":"476","DOI":"10.4065\/79.4.476","article-title":"Celiac disease serology in irritable bowel syndrome and dyspepsia: a population-based case-control study","volume":"79","author":"Locke","year":"2004","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.clnu.2014.08.012_bib18","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1155\/2011\/642452","article-title":"Testing for gluten-related disorders in clinical practice: the role of serology in managing the spectrum of gluten sensitivity","volume":"25","author":"Armstrong","year":"2011","journal-title":"Can J Gastroenterol"},{"key":"10.1016\/j.clnu.2014.08.012_bib19","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1159\/000321196","article-title":"Occurrence of nonceliac gluten sensitivity in patients with allergic disease","volume":"155","author":"Massari","year":"2011","journal-title":"Int Arch Allergy Immunol"},{"key":"10.1016\/j.clnu.2014.08.012_bib20","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1097\/MCG.0b013e3182372541","article-title":"Serological tests in gluten sensitivity (Nonceliac gluten intolerance)","volume":"46","author":"Volta","year":"2012","journal-title":"J Clin Gastroenterol"},{"key":"10.1016\/j.clnu.2014.08.012_bib21","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/1741-7015-9-23","article-title":"Divergence of gut permeability and mucosal immune gene expression in two gluten-associated conditions: celiac disease and gluten sensitivity","volume":"9","author":"Sapone","year":"2011","journal-title":"BMC Med"},{"key":"10.1016\/j.clnu.2014.08.012_bib22","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1097\/MPG.0b013e31821a23d0","article-title":"European Society for pediatric Gastroenterology, Hepatology, and Nutrition Guidelines for the diagnosis of coeliac disease","volume":"54","author":"Husby","year":"2012","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.clnu.2014.08.012_bib23","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1038\/ajg.2008.7","article-title":"Lymphocytic duodenosis and the spectrum of celiac disease","volume":"104","author":"Vande Voort","year":"2009","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.clnu.2014.08.012_bib24","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1053\/j.gastro.2010.04.007","article-title":"Detection of celiac disease and lymphocytic enteropathy by parallel serology and histopathology in a population-based study","volume":"139","author":"Walker","year":"2010","journal-title":"Gastroenterology"},{"key":"10.1016\/j.clnu.2014.08.012_bib25","doi-asserted-by":"crossref","first-page":"1898","DOI":"10.1038\/ajg.2012.236","article-title":"Non-celiac wheat sensitivity diagnosed by double-blind placebo-controlled challenge: exploring a new clinical entity","volume":"107","author":"Carroccio","year":"2012","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.clnu.2014.08.012_bib26","first-page":"115","article-title":"Non coeliac gluten sensitivity","volume":"6","author":"Holmes","year":"2013","journal-title":"Gastroenterol Hepatol Bed Bench"},{"key":"10.1016\/j.clnu.2014.08.012_bib27","doi-asserted-by":"crossref","first-page":"2520","DOI":"10.1038\/ajg.2010.276","article-title":"Update on serologic testing in celiac disease","volume":"105","author":"Leffler","year":"2010","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.clnu.2014.08.012_bib28","doi-asserted-by":"crossref","first-page":"1977","DOI":"10.1053\/j.gastro.2006.10.003","article-title":"AGA Institute medical position statement on the diagnosis and management of celiac disease","volume":"131","year":"2006","journal-title":"Gastroenterology"},{"key":"10.1016\/j.clnu.2014.08.012_bib29","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1097\/MPG.0b013e31817d80f4","article-title":"Antigliadin immunoglobulin A best in finding celiac disease in children younger than 18 months of age","volume":"47","author":"Lagerqvist","year":"2008","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.clnu.2014.08.012_bib30","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1097\/MPG.0b013e318216f2e5","article-title":"Accuracy of diagnostic antibody tests for coeliac disease in children: summary of an evidence report","volume":"54","author":"Giersiepen","year":"2012","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.clnu.2014.08.012_bib31","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1186\/1471-230X-14-26","article-title":"Effect of gluten free diet on immune response to gliadin in patients with non-celiac gluten sensitivity","volume":"14","author":"Caio","year":"2014","journal-title":"BMC Gastroentrol"},{"issue":"Suppl. 1","key":"10.1016\/j.clnu.2014.08.012_bib32","first-page":"S1","article-title":"An evidence-based position statement on the management of irritable bowel syndrome","volume":"104","author":"Brandt","year":"2009","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.clnu.2014.08.012_bib33","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1001\/archinternmed.2009.22","article-title":"Yield of diagnostic tests for celiac disease in individuals with symptoms suggestive of irritable bowel syndrome: systematic review and meta-analysis","volume":"169","author":"Ford","year":"2009","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.clnu.2014.08.012_bib34","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1053\/j.gastro.2004.03.012","article-title":"Testing for celiac sprue in irritable bowel syndrome with predominant diarrhea: a cost-effectiveness analysis","volume":"126","author":"Spiegel","year":"2004","journal-title":"Gastroenterology"},{"key":"10.1016\/j.clnu.2014.08.012_bib35","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1016\/0016-5085(93)90333-8","article-title":"Intestinal antibody pattern of celiac disease: occurrence in patients with normal jejuna biopsy histology","volume":"104","author":"Arranz","year":"1993","journal-title":"Gastroenterology"},{"key":"10.1016\/j.clnu.2014.08.012_bib36","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1053\/j.gastro.2013.01.049","article-title":"A controlled trial of gluten-free diet in patients with irritable bowel syndrome-diarrhea: effects on bowel frequency and intestinal function","volume":"144","author":"Vazquez-Roque","year":"2013","journal-title":"Gastroenterology"},{"issue":"3","key":"10.1016\/j.clnu.2014.08.012_bib37","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/j.jada.2009.01.013","article-title":"What is the current status of research concerning use of a gluten-free, casein-free diet for children diagnosed with autism?","volume":"109","author":"Marcason","year":"2009","journal-title":"J Am Diet Assoc"},{"key":"10.1016\/j.clnu.2014.08.012_bib38","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD003498.pub3","article-title":"Gluten- and casein-free diets for autistic spectrum disorder","volume":"2","author":"Millward","year":"2008","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.clnu.2014.08.012_bib39","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1093\/schbul\/sbp055","article-title":"Prevalence of celiac disease and gluten sensitivity in the United States clinical antipsychotic trials of intervention effectiveness study population","volume":"37","author":"Cascella","year":"2011","journal-title":"Schizophr Bull"},{"key":"10.1016\/j.clnu.2014.08.012_bib40","article-title":"Biomarkers of gluten sensitivity in patients with non-affective psychosis: a meta-analysis","author":"Lachance","year":"2013","journal-title":"Shizophr Res"},{"key":"10.1016\/j.clnu.2014.08.012_bib41","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1093\/schbul\/sbs064","article-title":"Increased prevalence of transglutaminase 6 antibodies in sera from schizophrenia patients","volume":"39","author":"Cascella","year":"2013","journal-title":"Schizophr Bull"},{"key":"10.1016\/j.clnu.2014.08.012_bib42","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.biopsych.2010.03.021","article-title":"Markers of gluten sensitivity and celiac disease in recent-onset psychosis and multi-episode schizophrenia","volume":"68","author":"Dickerson","year":"2010","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.clnu.2014.08.012_bib43","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1016\/j.cgh.2013.04.022","article-title":"Gliadin does not induce mucosal inflammation or basophil activation in patients with non-celiac gluten sensitivity","volume":"11","author":"Bucci","year":"2013","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.clnu.2014.08.012_bib44","doi-asserted-by":"crossref","first-page":"2395","DOI":"10.1084\/jem.20102660","article-title":"Wheat amylase trypsin inhibitors drive intestinal inflammation via activation of toll-like receptor 4","volume":"209","author":"Junker","year":"2012","journal-title":"J Exp Med"},{"key":"10.1016\/j.clnu.2014.08.012_bib45","first-page":"85","article-title":"What role does wheat play in the symptoms of irritable bowel syndrome?","volume":"9","author":"Eswaran","year":"2013","journal-title":"Gastroenterol Hepatol NY"},{"key":"10.1016\/j.clnu.2014.08.012_bib46","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1053\/j.gastro.2013.04.051","article-title":"No effects of gluten in patients with self-reported non-celiac gluten sensitivity following dietary reduction of low-fermentable, poorly absorbed, short-chain carbohydrates","volume":"145","author":"Biesiekierski","year":"2013","journal-title":"Gastroenterology"},{"key":"10.1016\/j.clnu.2014.08.012_bib47","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1177\/1756283X11436241","article-title":"Fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAPs) and nonallergic food intolerance: FODMAPs or food chemicals?","volume":"5","author":"Barrett","year":"2012","journal-title":"Ther Adv Gastroenterol"},{"key":"10.1016\/j.clnu.2014.08.012_bib48","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1038\/ajg.2013.91","article-title":"Mucosal cytokine response after short-term gluten challenge in celiac disease and non-celiac gluten sensitivity","volume":"108","author":"Brottveit","year":"2013","journal-title":"Am J Gastroenterol"},{"issue":"1 Suppl.","key":"10.1016\/j.clnu.2014.08.012_bib49","doi-asserted-by":"crossref","first-page":"68S","DOI":"10.1177\/0148607111426276","article-title":"Celiac disease, wheat allergy, and gluten sensitivity: when gluten free is not a fad","volume":"36","author":"Pietrzak","year":"2012","journal-title":"J Parenter Eternal Nutr"},{"key":"10.1016\/j.clnu.2014.08.012_bib50","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1038\/ajg.2014.41","article-title":"Celiac disease or non-celiac gluten sensitivity? An approach to clinical differential diagnosis","volume":"109","author":"Kabbani","year":"2014","journal-title":"Am J Gastroenterol"}],"container-title":["Clinical Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0261561414002180?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0261561414002180?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,14]],"date-time":"2019-08-14T09:27:01Z","timestamp":1565774821000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0261561414002180"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4]]},"references-count":50,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,4]]}},"alternative-id":["S0261561414002180"],"URL":"https:\/\/doi.org\/10.1016\/j.clnu.2014.08.012","relation":{},"ISSN":["0261-5614"],"issn-type":[{"value":"0261-5614","type":"print"}],"subject":[],"published":{"date-parts":[[2015,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Non coeliac gluten sensitivity \u2013 A new disease with gluten intolerance","name":"articletitle","label":"Article Title"},{"value":"Clinical Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clnu.2014.08.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 The Author. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}