{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T09:41:05Z","timestamp":1790502065378,"version":"4.1.0"},"reference-count":39,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2018,2,1]],"date-time":"2018-02-01T00:00:00Z","timestamp":1517443200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","journals.elsevierhealth.com","clinicalkey.com","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Nutrition"],"published-print":{"date-parts":[[2018,2]]},"DOI":"10.1016\/j.clnu.2016.12.012","type":"journal-article","created":{"date-parts":[[2016,12,21]],"date-time":"2016-12-21T15:16:39Z","timestamp":1482333399000},"page":"235-241","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":41,"title":["Defining the role of dietary intake in determining weight change in patients with cancer cachexia"],"prefix":"10.1016","volume":"37","author":[{"given":"R.","family":"Nasrah","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Kanbalian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Van Der Borch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Swinton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Wing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7069-0519","authenticated-orcid":false,"given":"R.T.","family":"Jagoe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.clnu.2016.12.012_bib1","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/S1470-2045(10)70218-7","article-title":"Definition and classification of cancer cachexia: an international consensus","volume":"12","author":"Fearon","year":"2011","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.clnu.2016.12.012_bib2","doi-asserted-by":"crossref","DOI":"10.1201\/b10936-10","article-title":"8 refractory cancer cachexia","volume":"89","author":"Blum","year":"2011","journal-title":"Diet Nutr Palliat Care"},{"key":"10.1016\/j.clnu.2016.12.012_bib3","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/S0149-2918(05)80001-3","article-title":"Prognostic effect of weight loss prior tochemotherapy in cancer patients","volume":"69","author":"Dewys","year":"1980","journal-title":"Am J Med"},{"key":"10.1016\/j.clnu.2016.12.012_bib4","doi-asserted-by":"crossref","first-page":"2557","DOI":"10.1111\/j.1572-0241.2007.01437.x","article-title":"Baseline nutritional status is predictive of response to treatment and survival in patients treated by definitive chemoradiotherapy for a locally advanced esophageal cancer","volume":"102","author":"Di Fiore","year":"2007","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.clnu.2016.12.012_bib5","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1016\/j.ejca.2008.04.006","article-title":"Relationship between nutritional status and quality of life in patients with cancer","volume":"44","author":"Nourissat","year":"2008","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.clnu.2016.12.012_bib6","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/j.clon.2005.03.015","article-title":"Nutrition support improves patient outcomes, treatment tolerance and admission characteristics in oesophageal cancer","volume":"17","author":"Odelli","year":"2005","journal-title":"Clin Oncol"},{"key":"10.1016\/j.clnu.2016.12.012_bib7","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1053\/gast.2001.28031","article-title":"AGA technical review on parenteral nutrition","volume":"121","author":"Koretz","year":"2001","journal-title":"Gastroenterology"},{"key":"10.1016\/j.clnu.2016.12.012_bib8","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/j.clnu.2009.04.011","article-title":"ESPEN guidelines on parenteral nutrition: non-surgical oncology","volume":"28","author":"Bozzetti","year":"2009","journal-title":"Clin Nutr"},{"key":"10.1016\/j.clnu.2016.12.012_bib9","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1177\/0148607195019003204","article-title":"Effect of enteral and parenteral nutrition on amino acid levels in cancer patients","volume":"19","author":"Pearlstone","year":"1995","journal-title":"J\u00a0Parenter Enter Nutr"},{"key":"10.1016\/j.clnu.2016.12.012_bib10","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/0022-4804(83)90076-8","article-title":"A\u00a0controlled, randomized trial evaluating the effects of enteral and parenteral nutrition on protein metabolism in cancer-bearing man","volume":"34","author":"Burt","year":"1983","journal-title":"J\u00a0Surg Res"},{"key":"10.1016\/j.clnu.2016.12.012_bib11","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1097\/00000658-198702000-00007","article-title":"Total parenteral nutrition prevents further nutritional deterioration in patients with cancer cachexia","volume":"205","author":"Bozzetti","year":"1987","journal-title":"Ann Surg"},{"key":"10.1016\/j.clnu.2016.12.012_bib12","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1002\/bjs.1800680202","article-title":"Total parenteral nutrition versus gastrostomy in the preoperative preparation of patients with carcinoma of the oesophagus","volume":"68","author":"Lim","year":"1981","journal-title":"Br J Surg"},{"key":"10.1016\/j.clnu.2016.12.012_bib13","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1097\/CCO.0b013e3283479c66","article-title":"Nutritional intervention for improving treatment tolerance in cancer patients","volume":"23","author":"Paccagnella","year":"2011","journal-title":"Curr Opin Oncol"},{"key":"10.1016\/j.clnu.2016.12.012_bib14","doi-asserted-by":"crossref","first-page":"e108687","DOI":"10.1371\/journal.pone.0108687","article-title":"Nutritional advice in older patients at risk of malnutrition during treatment for chemotherapy: a two-year randomized controlled trial","volume":"9","author":"Bourdel-Marchasson","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.clnu.2016.12.012_bib15","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1007\/s00520-004-0746-7","article-title":"Nutrition intervention improves outcomes in patients with cancer cachexia receiving chemotherapy\u2014a pilot study","volume":"13","author":"Bauer","year":"2005","journal-title":"Support Care Cancer"},{"key":"10.1016\/j.clnu.2016.12.012_bib16","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.3945\/ajcn.111.018838","article-title":"Individualized nutrition intervention is of major benefit to colorectal cancer patients: long-term follow-up of a randomized controlled trial of nutritional therapy","volume":"96","author":"Ravasco","year":"2012","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.clnu.2016.12.012_bib17","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1002\/hed.20221","article-title":"Impact of nutrition on outcome: a prospective randomized controlled trial in patients with head and neck cancer undergoing radiotherapy","volume":"27","author":"Ravasco","year":"2005","journal-title":"Head Neck"},{"key":"10.1016\/j.clnu.2016.12.012_bib18","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1200\/JCO.2005.02.054","article-title":"Dietary counseling improves patient outcomes: a prospective, randomized, controlled trial in colorectal cancer patients undergoing radiotherapy","volume":"23","author":"Ravasco","year":"2005","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.clnu.2016.12.012_bib19","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.critrevonc.2014.02.005","article-title":"Dietary treatment of weight loss in patients with advanced cancer and cachexia: a systematic literature review","volume":"91","author":"Balstad","year":"2014","journal-title":"Crit Rev Oncol Hematol"},{"key":"10.1016\/j.clnu.2016.12.012_bib20","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1111\/j.1365-277X.2011.01189.x","article-title":"Simple nutritional intervention in patients with advanced cancers of the gastrointestinal tract, non-small cell lung cancers or mesothelioma and weight loss receiving chemotherapy: a randomised controlled trial","volume":"24","author":"Baldwin","year":"2011","journal-title":"J\u00a0Hum Nutr Diet"},{"key":"10.1016\/j.clnu.2016.12.012_bib21","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1200\/JCO.1987.5.1.113","article-title":"A\u00a0randomized study of oral nutritional support versus ad lib nutritional intake during chemotherapy for advanced colorectal and non-small-cell lung cancer","volume":"5","author":"Evans","year":"1987","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.clnu.2016.12.012_bib22","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1007\/s00508-005-0455-3","article-title":"Effects of a high-fat diet on body composition in cancer patients receiving chemotherapy: a randomized controlled study","volume":"117","author":"Breitkreutz","year":"2005","journal-title":"Wien Klin Wochenschr"},{"key":"10.1016\/j.clnu.2016.12.012_bib23","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.clnu.2006.01.020","article-title":"ESPEN guidelines on enteral nutrition: non-surgical oncology","volume":"25","author":"Arends","year":"2006","journal-title":"Clin Nutr"},{"key":"10.1016\/j.clnu.2016.12.012_bib24","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1111\/j.1747-0080.2006.00099.x","article-title":"Evidence based practice guidelines for the nutritional management of cancer cachexia","volume":"63","author":"Bauer","year":"2006","journal-title":"Nutr Diet"},{"key":"10.1016\/j.clnu.2016.12.012_bib25","unstructured":"Meal planning for people with diabetes. In: Quebec D, editor. Quebec: Le minist\u00e8re de la Sant\u00e9 et des Services sociaux Qu\u00e9bec."},{"key":"10.1016\/j.clnu.2016.12.012_bib26","series-title":"R: a language and environment for statistical computing","author":"R Development Core Team","year":"2012"},{"key":"10.1016\/j.clnu.2016.12.012_bib27","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1200\/JCO.2014.56.1894","article-title":"Diagnostic criteria for the classification of cancer-associated weight loss","volume":"33","author":"Martin","year":"2015","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.clnu.2016.12.012_bib28","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1038\/sj.bjc.6601242","article-title":"Evaluation of cumulative prognostic scores based on the systemic inflammatory response in patients with inoperable non-small-cell lung cancer","volume":"89","author":"Forrest","year":"2003","journal-title":"Br J Cancer"},{"key":"10.1016\/j.clnu.2016.12.012_bib29","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1002\/jcsm.12014","article-title":"Hypermetabolism and symptom burden in advanced cancer patients evaluated in a cachexia clinic","volume":"6","author":"Dev","year":"2015","journal-title":"J\u00a0Cachexia Sarcopenia Muscle"},{"key":"10.1016\/j.clnu.2016.12.012_bib30","series-title":"A\u00a0randomised, open-label trial of a multimodal intervention (exercise, nutrition and anti-inflammatory medication) plus standard care versus standard care alone to prevent\/attenuate cachexia in advanced cancer patients undergoing chemotherapy","first-page":"9628","author":"Kaasa","year":"2015"},{"key":"10.1016\/j.clnu.2016.12.012_bib31","doi-asserted-by":"crossref","first-page":"S73","DOI":"10.1017\/S0007114509990602","article-title":"Misreporting of energy and micronutrient intake estimated by food records and 24 hour recalls, control and adjustment methods in practice","volume":"101","author":"Poslusna","year":"2009","journal-title":"Br J Nutr"},{"key":"10.1016\/j.clnu.2016.12.012_bib32","series-title":"Nutrition in the prevention and treatment of disease","first-page":"5","article-title":"Chapter 1-dietary assessment methodology","author":"Thompson","year":"2013"},{"key":"10.1016\/j.clnu.2016.12.012_bib33","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1093\/oxfordjournals.aje.a113331","article-title":"A\u00a0review of validations of dietary assessment methods","volume":"115","author":"Block","year":"1982","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.clnu.2016.12.012_bib34","doi-asserted-by":"crossref","first-page":"5220","DOI":"10.1210\/en.2007-0381","article-title":"A\u00a0central role for neuronal adenosine 5\u2032-monophosphate-activated protein kinase in cancer-induced anorexia","volume":"148","author":"Ropelle","year":"2007","journal-title":"Endocrinology"},{"key":"10.1016\/j.clnu.2016.12.012_bib35","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1016\/j.physbeh.2010.03.011","article-title":"Hypothalamic mechanisms in cachexia","volume":"100","author":"Grossberg","year":"2010","journal-title":"Physiol Behav"},{"key":"10.1016\/j.clnu.2016.12.012_bib36","doi-asserted-by":"crossref","first-page":"2449","DOI":"10.1084\/jem.20111020","article-title":"Central nervous system inflammation induces muscle atrophy via activation of the hypothalamic\u2013pituitary\u2013adrenal axis","volume":"208","author":"Braun","year":"2011","journal-title":"J\u00a0Exp Med"},{"key":"10.1016\/j.clnu.2016.12.012_bib37","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.yclnex.2015.11.001","article-title":"Nutrition in cancer patients with cachexia: a role for the gut microbiota?","volume":"6","author":"Bindels","year":"2016","journal-title":"Clin Nutr Exp"},{"key":"10.1016\/j.clnu.2016.12.012_bib38","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/S1470-2045(13)70055-X","article-title":"Effects of enobosarm on muscle wasting and physical function in patients with cancer: a double-blind, randomised controlled phase 2 trial","volume":"14","author":"Dobs","year":"2013","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.clnu.2016.12.012_bib39","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/S1470-2045(15)00558-6","article-title":"Anamorelin in patients with non-small-cell lung cancer and cachexia (ROMANA 1 and ROMANA 2): results from two randomised, double-blind, phase 3 trials","volume":"17","author":"Temel","year":"2016","journal-title":"Lancet Oncol"}],"container-title":["Clinical Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S026156141631353X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S026156141631353X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,3,25]],"date-time":"2019-03-25T07:10:50Z","timestamp":1553497850000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S026156141631353X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2]]},"references-count":39,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,2]]}},"alternative-id":["S026156141631353X"],"URL":"https:\/\/doi.org\/10.1016\/j.clnu.2016.12.012","relation":{},"ISSN":["0261-5614"],"issn-type":[{"value":"0261-5614","type":"print"}],"subject":[],"published":{"date-parts":[[2018,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Defining the role of dietary intake in determining weight change in patients with cancer cachexia","name":"articletitle","label":"Article Title"},{"value":"Clinical Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clnu.2016.12.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.","name":"copyright","label":"Copyright"}]}}