{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T15:56:33Z","timestamp":1784044593624,"version":"3.55.0"},"reference-count":75,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"NUTRIM Graduate Programme"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","clinicalnutritionjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Nutrition"],"published-print":{"date-parts":[[2020,8]]},"DOI":"10.1016\/j.clnu.2019.11.033","type":"journal-article","created":{"date-parts":[[2019,12,3]],"date-time":"2019-12-03T02:11:22Z","timestamp":1575339082000},"page":"2600-2608","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":24,"title":["Prediction model for tube feeding dependency during chemoradiotherapy for at least four weeks in head and neck cancer patients: A tool for prophylactic gastrostomy decision making"],"prefix":"10.1016","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8595-0739","authenticated-orcid":false,"given":"Anna C.H.","family":"Willemsen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annemieke","family":"Kok","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sander M.J.","family":"van Kuijk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1406-6425","authenticated-orcid":false,"given":"Laura W.J.","family":"Baijens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Remco","family":"de Bree","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lot A.","family":"Devriese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank J.P.","family":"Hoebers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9752-0947","authenticated-orcid":false,"given":"Roy I.","family":"Lalisang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9878-0428","authenticated-orcid":false,"given":"Annemie M.W.J.","family":"Schols","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris H.J.","family":"Terhaard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann","family":"Hoeben","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.clnu.2019.11.033_bib1","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S1470-2045(09)70311-0","article-title":"Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survival","volume":"11","author":"Bonner","year":"2010","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.clnu.2019.11.033_bib2","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1056\/NEJMoa053422","article-title":"Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck","volume":"354","author":"Bonner","year":"2006","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.clnu.2019.11.033_bib3","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.radonc.2011.05.036","article-title":"Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): a comprehensive analysis by tumour site","volume":"100","author":"Blanchard","year":"2011","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.clnu.2019.11.033_bib4","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.radonc.2009.04.014","article-title":"Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): an update on 93 randomised trials and 17,346 patients","volume":"92","author":"Pignon","year":"2009","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.clnu.2019.11.033_bib5","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/S0167-8140(02)00404-8","article-title":"Mucositis incidence, severity and associated outcomes in patients with head and neck cancer receiving radiotherapy with or without chemotherapy: a systematic literature review","volume":"66","author":"Trotti","year":"2003","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.clnu.2019.11.033_bib6","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1111\/coa.12002","article-title":"Outcome and toxicity of radiotherapy combined with chemotherapy or cetuximab for head and neck cancer: our experience in one hundred and twenty-five patients","volume":"38","author":"Beijer","year":"2013","journal-title":"Clin Otolaryngol"},{"key":"10.1016\/j.clnu.2019.11.033_bib7","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1111\/j.1365-2273.2004.00892.x","article-title":"Simultaneous radio- and chemotherapy for squamous cell carcinoma of the head and neck in daily clinical practice: 5 years experience in a University Hospital","volume":"29","author":"Langenberg","year":"2004","journal-title":"Clin Otolaryngol Allied Sci"},{"key":"10.1016\/j.clnu.2019.11.033_bib8","first-page":"371","article-title":"Nutritional support of patients undergoing radiation therapy for head and neck cancer","volume":"19","author":"Colasanto","year":"2005","journal-title":"Oncology"},{"key":"10.1016\/j.clnu.2019.11.033_bib9","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1186\/s40064-016-2076-x","article-title":"Investigating the clinical significance of body composition changes in patients undergoing chemoradiation for oropharyngeal cancer using analytic morphomics","volume":"5","author":"Wang","year":"2016","journal-title":"SpringerPplus"},{"key":"10.1016\/j.clnu.2019.11.033_bib10","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1002\/hed.20607","article-title":"Changes in body mass, energy balance, physical function, and inflammatory state in patients with locally advanced head and neck cancer treated with concurrent chemoradiation after low-dose induction chemotherapy","volume":"29","author":"Silver","year":"2007","journal-title":"Head Neck"},{"key":"10.1016\/j.clnu.2019.11.033_bib11","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1002\/hed.20737","article-title":"Influence of weight loss on outcomes in patients with head and neck cancer undergoing concomitant chemoradiotherapy","volume":"30","author":"Capuano","year":"2008","journal-title":"Head Neck"},{"key":"10.1016\/j.clnu.2019.11.033_bib12","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1038\/sj.bjc.6601962","article-title":"Nutrition intervention is beneficial in oncology outpatients receiving radiotherapy to the gastrointestinal or head and neck area","volume":"91","author":"Isenring","year":"2004","journal-title":"Br J Cancer"},{"key":"10.1016\/j.clnu.2019.11.033_bib13","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.clnu.2006.01.020","article-title":"ESPEN guidelines on enteral nutrition: Non-surgical oncology","volume":"25","author":"Arends","year":"2006","journal-title":"Clin Nutr"},{"key":"10.1016\/j.clnu.2019.11.033_bib14","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1080\/00016489.2016.1277263","article-title":"Cachexia at diagnosis is associated with poor survival in head and neck cancer patients","volume":"137","author":"Orell-Kotikangas","year":"2017","journal-title":"Acta Otolaryngol"},{"key":"10.1016\/j.clnu.2019.11.033_bib15","first-page":"267","article-title":"The provision of enteral nutritional support during definitive chemoradiotherapy in head and neck cancer patients","volume":"62","author":"Bishop","year":"2015","journal-title":"J\u00a0Med Imaging Radiat Sci"},{"key":"10.1016\/j.clnu.2019.11.033_bib16","doi-asserted-by":"crossref","first-page":"265","DOI":"10.3390\/nu7010265","article-title":"Nutritional interventions in head and neck cancer patients undergoing chemoradiotherapy: a narrative review","volume":"7","author":"Bossola","year":"2015","journal-title":"Nutrients"},{"key":"10.1016\/j.clnu.2019.11.033_bib17","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1002\/hed.23146","article-title":"Validated swallowing and nutrition guidelines for patients with head and neck cancer: identification of high-risk patients for proactive gastrostomy","volume":"35","author":"Brown","year":"2013","journal-title":"Head Neck"},{"key":"10.1016\/j.clnu.2019.11.033_bib18","series-title":"Human nutrition and dietetics","first-page":"490","author":"Garrow","year":"2000"},{"key":"10.1016\/j.clnu.2019.11.033_bib19","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1016\/j.ijrobp.2009.09.036","article-title":"Evaluating the role of prophylactic gastrostomy tube placement prior to definitive chemoradiotherapy for head and neck cancer","volume":"78","author":"Chen","year":"2010","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.clnu.2019.11.033_bib20","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1002\/hed.21164","article-title":"Late esophageal toxicity after radiation therapy for head and neck cancer","volume":"32","author":"Chen","year":"2010","journal-title":"Head Neck"},{"key":"10.1016\/j.clnu.2019.11.033_bib21","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1001\/jamaoto.2013.4715","article-title":"Eat and exercise during radiotherapy or chemoradiotherapy for pharyngeal cancers: use it or lose it","volume":"139","author":"Hutcheson","year":"2013","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.clnu.2019.11.033_bib22","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1097\/MCG.0000000000001082","article-title":"A systematic review and meta-analysis on outcomes and complications of percutaneous endoscopic versus radiologic gastrostomy for enteral feeding","volume":"52","author":"Strijbos","year":"2018","journal-title":"J\u00a0Clin Gastroenterol"},{"key":"10.1016\/j.clnu.2019.11.033_bib23","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1111\/j.1749-4486.2009.01889.x","article-title":"Complications following gastrostomy tube insertion in patients with head and neck cancer: a prospective multi-institution study, systematic review and meta-analysis","volume":"34","author":"Grant","year":"2009","journal-title":"Clin Otolaryngol"},{"key":"10.1016\/j.clnu.2019.11.033_bib24","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1177\/0884533616682684","article-title":"Indicators for enteral nutrition use and prophylactic percutaneous endoscopic gastrostomy placement in patients with head and neck cancer undergoing chemoradiotherapy","volume":"32","author":"van der Linden","year":"2017","journal-title":"Nutr Clin Pract"},{"key":"10.1016\/j.clnu.2019.11.033_bib25","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.3748\/wjg.v17.i8.1004","article-title":"Prophylactic PEG placement in head and neck cancer: how many feeding tubes are unused (and unnecessary)?","volume":"17","author":"Madhoun","year":"2011","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.clnu.2019.11.033_bib26","article-title":"Richtlijn hoofd-halstumoren","volume":"18","author":"Leemans LES","year":"2014"},{"key":"10.1016\/j.clnu.2019.11.033_bib27","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1038\/ejcn.2015.230","article-title":"Validation of an updated evidence-based protocol for proactive gastrostomy tube insertion in patients with head and neck cancer","volume":"70","author":"Brown","year":"2016","journal-title":"Eur J Clin Nutr"},{"key":"10.1016\/j.clnu.2019.11.033_bib28","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.oraloncology.2018.11.031","article-title":"From reactive to proactive tube feeding during chemoradiotherapy for head and neck cancer: a clinical prediction model-based approach","volume":"88","author":"Karsten","year":"2019","journal-title":"Oral Oncol"},{"key":"10.1016\/j.clnu.2019.11.033_bib29","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.radonc.2013.05.021","article-title":"Predictors of PEG dependence after IMRT+\/-chemotherapy for oropharyngeal cancer","volume":"107","author":"Sanguineti","year":"2013","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.clnu.2019.11.033_bib30","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1097\/JTO.0b013e3181fbebfd","article-title":"Comparison of platinum-based chemotherapy in patients older and younger than 70 years: an analysis of Southwest Oncology Group Trials 9308 and 9509","volume":"6","author":"Blanchard","year":"2011","journal-title":"J\u00a0Thorac Oncol"},{"issue":"November","key":"10.1016\/j.clnu.2019.11.033_bib31","first-page":"112","article-title":"Landelijke multidisciplinaire richtlijn Neusmaagsonde","author":"de Boer","year":"2011","journal-title":"Verpleegkundigen & Verzorgenden Nederland"},{"key":"10.1016\/j.clnu.2019.11.033_bib32","unstructured":"Stuurgroep ondervoeding, (2019). Kiezen toedieningsweg. Retrieved from https:\/\/www.stuurgroepondervoeding.nl\/stappen-sondevoeding"},{"issue":"August","key":"10.1016\/j.clnu.2019.11.033_bib33","first-page":"36","article-title":"Richtlijn ondervoeding","author":"Kruizenga","year":"2017","journal-title":"Stuurgroep Ondervoeding"},{"key":"10.1016\/j.clnu.2019.11.033_bib34","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1002\/hed.24630","article-title":"Investigation of p16 status, chemotherapy regimen, and other nutrition markers for predicting gastrostomy in patients with head and neck cancer","volume":"39","author":"Brown","year":"2017","journal-title":"Head Neck"},{"key":"10.1016\/j.clnu.2019.11.033_bib35","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1001\/archotol.132.6.655","article-title":"Variables associated with feeding tube placement in head and neck cancer","volume":"132","author":"Cheng","year":"2006","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.clnu.2019.11.033_bib36","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.amjoto.2008.06.010","article-title":"Percutaneous feeding tubes in patients with head and neck cancer: rethinking prophylactic placement for patients undergoing chemoradiation","volume":"30","author":"Lawson","year":"2009","journal-title":"Am J Otolaryngol"},{"key":"10.1016\/j.clnu.2019.11.033_bib37","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.3109\/0284186X.2013.824609","article-title":"Factors associated with acute and late dysphagia in the DAHANCA 6 & 7 randomized trial with accelerated radiotherapy for head and neck cancer","volume":"52","author":"Mortensen","year":"2013","journal-title":"Acta Oncol"},{"key":"10.1016\/j.clnu.2019.11.033_bib38","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1186\/s13014-015-0408-6","article-title":"Age most significant predictor of requiring enteral feeding in head-and-neck cancer patients","volume":"10","author":"Sachdev","year":"2015","journal-title":"Radiat Oncol"},{"key":"10.1016\/j.clnu.2019.11.033_bib39","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1002\/cncr.29022","article-title":"A multi-institution pooled analysis of gastrostomy tube dependence in patients with oropharyngeal cancer treated with definitive intensity-modulated radiotherapy","volume":"121","author":"Setton","year":"2015","journal-title":"Cancer"},{"key":"10.1016\/j.clnu.2019.11.033_bib40","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1001\/jamaoto.2013.5193","article-title":"Risk factors for percutaneous endoscopic gastrostomy tube placement during chemoradiotherapy for oropharyngeal cancer","volume":"139","author":"Strom","year":"2013","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.clnu.2019.11.033_bib41","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.oraloncology.2011.11.005","article-title":"Prediction model for early percutaneous endoscopic gastrostomy (PEG) in head and neck cancer treatment","volume":"48","author":"Wermker","year":"2012","journal-title":"Oral Oncol"},{"key":"10.1016\/j.clnu.2019.11.033_bib42","doi-asserted-by":"crossref","first-page":"1634","DOI":"10.1002\/hed.23200","article-title":"Gastrostomy tube placement in patients with oropharyngeal carcinoma treated with radiotherapy or chemoradiotherapy: factors affecting placement and dependence","volume":"35","author":"Bhayani","year":"2013","journal-title":"Head Neck"},{"key":"10.1016\/j.clnu.2019.11.033_bib43","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.radonc.2018.09.013","article-title":"External validation of a multifactorial normal tissue complication probability model for tube feeding dependence at 6months after definitive radiotherapy for head and neck cancer","volume":"129","author":"Kanayama","year":"2018","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.clnu.2019.11.033_bib44","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.radonc.2016.05.017","article-title":"Influence of dosimetric and clinical criteria on the requirement of artificial nutrition during radiotherapy of head and neck cancer patients","volume":"120","author":"Matuschek","year":"2016","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.clnu.2019.11.033_bib45","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.radonc.2008.03.010","article-title":"Predictors of acute grade 4 swallowing toxicity in patients with stages III and IV squamous carcinoma of the head and neck treated with radiotherapy alone","volume":"87","author":"Poulsen","year":"2008","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.clnu.2019.11.033_bib46","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1007\/s00455-015-9679-1","article-title":"Predictive factors for prophylactic percutaneous endoscopic gastrostomy (PEG) tube placement and use in head and neck patients following intensity-modulated radiation therapy (IMRT) treatment: Concordance, discrepancies, and the role of gabapentin","volume":"31","author":"Yang","year":"2016","journal-title":"Dysphagia"},{"issue":"Suppl 1","key":"10.1016\/j.clnu.2019.11.033_bib47","first-page":"E1163","article-title":"Improving guideline sensitivity and specificity for the identification of proactive gastrostomy placement in patients with head and neck cancer","volume":"38","author":"Brown","year":"2016","journal-title":"Head Neck"},{"key":"10.1016\/j.clnu.2019.11.033_bib48","first-page":"457","article-title":"Factors associated with gastrostomy tube dependence after concurrent chemoradiotherapy for hypopharyngeal cancer","volume":"23","author":"Murono","year":"2015","journal-title":"Support Care Cancer"},{"key":"10.1016\/j.clnu.2019.11.033_bib49","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1007\/s00405-016-4241-9","article-title":"Pretreatment factors associated with functional oral intake and feeding tube use at 1 and 6 months post-radiotherapy (+\/- chemotherapy) for head and neck cancer","volume":"274","author":"Barnhart","year":"2017","journal-title":"Eur Arch Oto-Rhino-Laryngol"},{"key":"10.1016\/j.clnu.2019.11.033_bib50","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1093\/annonc\/mdp268","article-title":"Clinical and dosimetric factors associated with a prolonged feeding tube requirement in patients treated with chemoradiotherapy (CRT) for head and neck cancers","volume":"21","author":"Gokhale","year":"2010","journal-title":"Ann Oncol"},{"key":"10.1016\/j.clnu.2019.11.033_bib51","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1080\/00016489.2016.1245864","article-title":"Predicting feeding tube and tracheotomy dependence in laryngeal cancer patients","volume":"137","author":"Lavo","year":"2017","journal-title":"Acta Otolaryngol"},{"key":"10.1016\/j.clnu.2019.11.033_bib52","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1245\/s10434-010-0985-4","article-title":"The American Joint Committee on Cancer: the 7th edition of the AJCC cancer staging manual and the future of TNM","volume":"17","author":"Edge","year":"2010","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.clnu.2019.11.033_bib53","doi-asserted-by":"crossref","first-page":"3741","DOI":"10.1007\/s00405-017-4681-x","article-title":"Clinical predictors for reactive tube feeding in patients with advanced oropharynx cancer receiving radiotherapy +\/- chemotherapy","volume":"274","author":"Vangelov","year":"2017","journal-title":"Eur Arch Oto-Rhino-Laryngol"},{"key":"10.1016\/j.clnu.2019.11.033_bib54","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1016\/S0895-4356(96)00236-3","article-title":"A simulation study of the number of events per variable in logistic regression analysis","volume":"49","author":"Peduzzi","year":"1996","journal-title":"J\u00a0Clin Epidemiol"},{"key":"10.1016\/j.clnu.2019.11.033_bib55","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1136\/heartjnl-2011-301246","article-title":"Risk prediction models: I. Development, internal validation, and assessing the incremental value of a new (bio)marker","volume":"98","author":"Moons","year":"2012","journal-title":"Heart"},{"key":"10.1016\/j.clnu.2019.11.033_bib56","series-title":"Regression modeling Strategies","author":"Harrell","year":"2015"},{"key":"10.1016\/j.clnu.2019.11.033_bib57","series-title":"Applied logistic regression","author":"Hosmer","year":"2000"},{"key":"10.1016\/j.clnu.2019.11.033_bib58","series-title":"R: A language and environment for statistical computing","author":"R Foundation for Statistical Computing","year":"2018"},{"key":"10.1016\/j.clnu.2019.11.033_bib59","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1002\/hed.21218","article-title":"Impact of demographics, tumor characteristics, and treatment factors on swallowing after (chemo)radiotherapy for head and neck cancer","volume":"32","author":"Frowen","year":"2010","journal-title":"Head Neck"},{"key":"10.1016\/j.clnu.2019.11.033_bib60","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.radonc.2013.06.001","article-title":"Late dysphagia after IMRT for head and neck cancer and correlation with dose-volume parameters","volume":"107","author":"Mortensen","year":"2013","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.clnu.2019.11.033_bib61","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1016\/j.otohns.2004.05.020","article-title":"Functional outcomes following chemoradiotherapy for head and neck cancer","volume":"131","author":"Akst","year":"2004","journal-title":"Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.clnu.2019.11.033_bib62","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.radonc.2012.06.004","article-title":"Xerostomia: a day and night difference","volume":"104","author":"Dijkema","year":"2012","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.clnu.2019.11.033_bib63","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1016\/j.ijrobp.2009.07.1685","article-title":"A comparison of dose-response models for the parotid gland in a large group of head-and-neck cancer patients","volume":"76","author":"Houweling","year":"2010","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.clnu.2019.11.033_bib64","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.radonc.2008.04.008","article-title":"Sparing the contralateral submandibular gland in oropharyngeal cancer patients: a planning study","volume":"89","author":"Houweling","year":"2008","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.clnu.2019.11.033_bib65","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.oraloncology.2017.07.017","article-title":"Tube feeding during treatment for head and neck cancer - adherence and patient reported barriers","volume":"72","author":"Brown","year":"2017","journal-title":"Oral Oncol"},{"key":"10.1016\/j.clnu.2019.11.033_bib66","doi-asserted-by":"crossref","DOI":"10.3390\/cancers8020021","article-title":"Nephrotoxicity as a dose-limiting factor in a high-dose cisplatin-based chemoradiotherapy regimen for head and neck carcinomas","volume":"8","author":"Hoek","year":"2016","journal-title":"Cancers"},{"key":"10.1016\/j.clnu.2019.11.033_bib67","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/hed.21700","article-title":"Impact of prophylactic percutaneous endoscopic gastrostomy on malnutrition and quality of life in patients with head and neck cancer: a randomized study","volume":"34","author":"Silander","year":"2012","journal-title":"Head Neck"},{"key":"10.1016\/j.clnu.2019.11.033_bib68","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.radonc.2009.05.016","article-title":"Impact of the prophylactic gastrostomy for unresectable squamous cell head and neck carcinomas treated with radio-chemotherapy on quality of life: prospective randomized trial","volume":"93","author":"Salas","year":"2009","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.clnu.2019.11.033_bib69","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1007\/s00455-011-9360-2","article-title":"Does PEG use cause dysphagia in head and neck cancer patients?","volume":"27","author":"Langmore","year":"2012","journal-title":"Dysphagia"},{"key":"10.1016\/j.clnu.2019.11.033_bib70","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1016\/j.oraloncology.2011.07.011","article-title":"The impact of enteral feeding route on patient-reported long term swallowing outcome after chemoradiation for head and neck cancer","volume":"47","author":"Oozeer","year":"2011","journal-title":"Oral Oncol"},{"key":"10.1016\/j.clnu.2019.11.033_bib71","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.oraloncology.2016.06.007","article-title":"Impact of prophylactic gastrostomy or reactive NG tube upon patient-reported long term swallow function following chemoradiotherapy for oropharyngeal carcinoma: a matched pair analysis","volume":"59","author":"Sethugavalar","year":"2016","journal-title":"Oral Oncol"},{"key":"10.1016\/j.clnu.2019.11.033_bib72","series-title":"Effect of prophylactic percutaneous endoscopic gastrostomy tube on swallowing in advanced head and neck cancer: a randomized controlled study","author":"Axelsson","year":"2017"},{"issue":"6","key":"10.1016\/j.clnu.2019.11.033_bib73","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1111\/coa.12836","article-title":"Swallowing outcomes for patients with oropharyngeal squamous cell carcinoma treated with primary (chemo)radiation therapy receiving either prophylactic gastrostomy or reactive nasogastric tube: a prospective cohort study","volume":"42","author":"Goff","year":"2017","journal-title":"Clin Otolaryngol"},{"key":"10.1016\/j.clnu.2019.11.033_bib74","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.clon.2013.10.005","article-title":"Long-term swallow function after chemoradiotherapy for oropharyngeal cancer: the influence of a prophylactic gastrostomy or reactive nasogastric tube","volume":"26","author":"Prestwich","year":"2014","journal-title":"Clin Oncol"},{"key":"10.1016\/j.clnu.2019.11.033_bib75","doi-asserted-by":"crossref","first-page":"1943","DOI":"10.1002\/hed.24710","article-title":"Efficacy of a novel swallowing exercise program for chronic dysphagia in long-term head and neck cancer survivors","volume":"39","author":"Kraaijenga","year":"2017","journal-title":"Head Neck"}],"container-title":["Clinical Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0261561419331607?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0261561419331607?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T00:58:31Z","timestamp":1759366711000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0261561419331607"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8]]},"references-count":75,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2020,8]]}},"alternative-id":["S0261561419331607"],"URL":"https:\/\/doi.org\/10.1016\/j.clnu.2019.11.033","relation":{},"ISSN":["0261-5614"],"issn-type":[{"value":"0261-5614","type":"print"}],"subject":[],"published":{"date-parts":[[2020,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prediction model for tube feeding dependency during chemoradiotherapy for at least four weeks in head and neck cancer patients: A tool for prophylactic gastrostomy decision making","name":"articletitle","label":"Article Title"},{"value":"Clinical Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clnu.2019.11.033","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.","name":"copyright","label":"Copyright"}]}}