{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T15:39:04Z","timestamp":1787585944510,"version":"build-2736575974"},"reference-count":24,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100011947","name":"Abbott Nutrition","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011947","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","clinicalnutritionjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Nutrition"],"published-print":{"date-parts":[[2021,3]]},"DOI":"10.1016\/j.clnu.2020.08.035","type":"journal-article","created":{"date-parts":[[2020,9,6]],"date-time":"2020-09-06T02:37:30Z","timestamp":1599359850000},"page":"844-849","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":50,"title":["Specialized oral nutritional supplement (ONS) improves handgrip strength in hospitalized, malnourished older patients with cardiovascular and pulmonary disease: A randomized clinical trial"],"prefix":"10.1016","volume":"40","author":[{"given":"Eric M.","family":"Matheson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8951-1090","authenticated-orcid":false,"given":"Jeffrey L.","family":"Nelson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9419-7040","authenticated-orcid":false,"given":"Geraldine E.","family":"Baggs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Menghua","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolaas E.","family":"Deutz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"21","key":"10.1016\/j.clnu.2020.08.035_bib1","doi-asserted-by":"crossref","first-page":"2013","DOI":"10.1001\/jama.281.21.2013","article-title":"Protein-energy undernutrition among elderly hospitalized patients: a prospective study","volume":"281","author":"Sullivan","year":"1999","journal-title":"J\u00a0Am Med Assoc"},{"key":"10.1016\/j.clnu.2020.08.035_bib2","first-page":"295","article-title":"Ageing and muscle: the effects of malnutrition, re-nutrition, and physical exercise","volume":"4","author":"Hebuterne","year":"2001","journal-title":"Curr Opin Clin Nutr Met Care"},{"key":"10.1016\/j.clnu.2020.08.035_bib3","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/S0140-6736(14)62000-6","article-title":"Prognostic value of grip strength: findings from the Prospective Urban Rural Epidemiology (PURE) study","volume":"386","author":"Leong","year":"2015","journal-title":"Lancet"},{"issue":"4","key":"10.1016\/j.clnu.2020.08.035_bib4","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.amjmed.2006.04.018","article-title":"Grip strength predicts cause-specific mortality in middle-aged and elderly persons","volume":"120","author":"Sasaki","year":"2007","journal-title":"Am J Med"},{"issue":"1","key":"10.1016\/j.clnu.2020.08.035_bib5","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1093\/gerona\/61.1.72","article-title":"Strength, but not muscle mass, is associated with mortality in the health, aging and body composition study cohort","volume":"61","author":"Newman","year":"2006","journal-title":"J\u00a0Gerontol A Biol Sci Med Sci"},{"issue":"1","key":"10.1016\/j.clnu.2020.08.035_bib6","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1136\/thoraxjnl-2015-207451","article-title":"Handgrip weakness and mortality risk in COPD: a multicentre analysis","volume":"71","author":"Burtin","year":"2016","journal-title":"Thorax"},{"key":"10.1016\/j.clnu.2020.08.035_bib7","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1183\/09031936.00131612","article-title":"Simple functional performance tests and mortality in COPD","volume":"42","author":"Puhan","year":"2013","journal-title":"Eur Respir J"},{"key":"10.1016\/j.clnu.2020.08.035_bib8","series-title":"Patient safety and quality: an evidence-based handbook for nurses","article-title":"Reducing functional decline in hospitalized elderly","author":"Kleinpell","year":"2008"},{"issue":"6","key":"10.1016\/j.clnu.2020.08.035_bib9","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1016\/j.clnu.2016.04.008","article-title":"Lower handgrip strength at discharge from acute care hospitals is associated with 30-day readmission: a prospective cohort study","volume":"35","author":"Allard","year":"2016","journal-title":"Clin Nutr"},{"key":"10.1016\/j.clnu.2020.08.035_bib10","series-title":"65+ in the United States: 2005 current population report US census bureau","author":"He","year":"2005"},{"key":"10.1016\/j.clnu.2020.08.035_bib11","series-title":"Federal interagency forum on aging-related statistics","year":"2004"},{"issue":"6","key":"10.1016\/j.clnu.2020.08.035_bib12","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1001\/archinte.1996.00440060067008","article-title":"Functional outcomes of acute medical illness and hospitalization in older persons","volume":"156","author":"Sager","year":"1996","journal-title":"Arch Intern Med"},{"issue":"4","key":"10.1016\/j.clnu.2020.08.035_bib13","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1046\/j.1532-5415.2003.51152.x","article-title":"Loss of independence in activities of daily living in older adults hospitalized with medical illnesses: increased vulnerability with age","volume":"51","author":"Covinsky","year":"2003","journal-title":"JAGS"},{"issue":"5","key":"10.1016\/j.clnu.2020.08.035_bib14","doi-asserted-by":"crossref","first-page":"M189","DOI":"10.1093\/gerona\/51A.5.M189","article-title":"Risk factors for nursing home use after hospitalization for medical illness","volume":"51A","author":"Rudberg","year":"1996","journal-title":"J\u00a0Gerontol A Biol Sci Med Sci"},{"issue":"5","key":"10.1016\/j.clnu.2020.08.035_bib15","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1016\/j.clnu.2013.02.011","article-title":"Effect of \u03b2-hydroxy-\u03b2-methylbutyrate (HMB) on lean body mass during 10 days of bed rest in older adults","volume":"32","author":"Deutz","year":"2013","journal-title":"Clin Nutr"},{"issue":"1","key":"10.1016\/j.clnu.2020.08.035_bib16","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.clnu.2015.12.010","article-title":"Readmission and mortality in malnourished, older, hospitalized adults treated with a specialized oral nutritional supplement: a randomized clinical trial","volume":"35","author":"Deutz","year":"2016","journal-title":"Clin Nutr"},{"issue":"8","key":"10.1016\/j.clnu.2020.08.035_bib17","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/j.amjmed.2005.12.006","article-title":"A\u00a0randomized, double-blind, placebo-controlled trial of nutritional supplementation during acute illness","volume":"119","author":"Gariballa","year":"2006","journal-title":"Am J Med"},{"issue":"7","key":"10.1016\/j.clnu.2020.08.035_bib18","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/j.annepidem.2005.10.006","article-title":"Age trajectories of grip strength: cross-sectional and longitudinal data among 8,342 Danes aged 46 to 102","volume":"16","author":"Frederiksen","year":"2006","journal-title":"Ann Epidemiol"},{"key":"10.1016\/j.clnu.2020.08.035_bib19","article-title":"What are the association patterns between handgrip strength and adverse health conditions?","author":"McGrath","year":"2020","journal-title":"SAGE Journals"},{"issue":"6","key":"10.1016\/j.clnu.2020.08.035_bib20","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1007\/BF03327406","article-title":"Hand grip strength and incident ADL disability in elderly Mexican Americans over a seven-year period","volume":"16","author":"Al Snih","year":"2004","journal-title":"Aging Clin Exp Res"},{"issue":"3","key":"10.1016\/j.clnu.2020.08.035_bib21","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1007\/s12603-019-1170-5","article-title":"Association of handgrip strength and muscle mass with dependency in (instrumental) activities of daily living in hospitalized older adults- the EMPOWER study","volume":"23","author":"Meskers","year":"2019","journal-title":"J\u00a0Nutr Health Aging"},{"issue":"2","key":"10.1016\/j.clnu.2020.08.035_bib22","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.clnu.2010.09.010","article-title":"Hand grip strength: outcome predictor and marker of nutritional status","volume":"30","author":"Norman","year":"2011","journal-title":"Clin Nutr"},{"key":"10.1016\/j.clnu.2020.08.035_bib23","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1007\/s41999-018-0109-4","article-title":"AdNut study: effectiveness of a high calorie and protein oral nutritional supplement with \u03b2-hydroxy-\u03b2-methylbutyrate in an older malnourished population in usual clinical practice","volume":"9","author":"de Luis","year":"2018","journal-title":"European Geriatric Medicine"},{"key":"10.1016\/j.clnu.2020.08.035_bib24","doi-asserted-by":"crossref","first-page":"1879","DOI":"10.1016\/j.clnu.2017.09.004","article-title":"Oral nutrition support with or without exercise in the management of malnutrition in nutritionally vulnerable older people: a systematic review and meta-analysis","volume":"37","author":"Wrigth","year":"2018","journal-title":"Clin Nutr"}],"container-title":["Clinical Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0261561420304519?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0261561420304519?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T01:08:22Z","timestamp":1759367302000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0261561420304519"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":24,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["S0261561420304519"],"URL":"https:\/\/doi.org\/10.1016\/j.clnu.2020.08.035","relation":{},"ISSN":["0261-5614"],"issn-type":[{"value":"0261-5614","type":"print"}],"subject":[],"published":{"date-parts":[[2021,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Specialized oral nutritional supplement (ONS) improves handgrip strength in hospitalized, malnourished older patients with cardiovascular and pulmonary disease: A randomized clinical trial","name":"articletitle","label":"Article Title"},{"value":"Clinical Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clnu.2020.08.035","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.","name":"copyright","label":"Copyright"}]}}