{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T16:01:42Z","timestamp":1792425702936,"version":"4.5.0"},"reference-count":31,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","clinicalnutritionjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Nutrition"],"published-print":{"date-parts":[[2021,6]]},"DOI":"10.1016\/j.clnu.2021.02.016","type":"journal-article","created":{"date-parts":[[2021,2,23]],"date-time":"2021-02-23T05:13:27Z","timestamp":1614057207000},"page":"4037-4042","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":37,"title":["Cancer-associated anorexia: Validity and performance overtime of different appetite tools among patients at their first cancer diagnosis"],"prefix":"10.1016","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6432-0236","authenticated-orcid":false,"given":"Alessio","family":"Molfino","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5693-0811","authenticated-orcid":false,"given":"Marian A.E.","family":"de van der Schueren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karla","family":"S\u00e1nchez-Lara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pilar","family":"Milke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1294-9403","authenticated-orcid":false,"given":"Maria Ida","family":"Amabile","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Imbimbo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Di Lazzaro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvio","family":"Cavuto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Ronzani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anton","family":"Snegovoy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ioannis","family":"Gioulbasanis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9809-3553","authenticated-orcid":false,"given":"Alessandro","family":"Laviano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.clnu.2021.02.016_bib1","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1097\/SPC.0b013e32833e4aa5","article-title":"Contribution of anorexia to tissue wasting in cachexia","volume":"4","author":"Molfino","year":"2010","journal-title":"Curr Opin Support Palliat Care"},{"key":"10.1016\/j.clnu.2021.02.016_bib2","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.clnu.2009.12.004","article-title":"Consensus definition of sarcopenia, cachexia and pre-cachexia: joint document elaborated by Special Interest Groups (SIG) \"cachexia-anorexia in chronic wasting diseases\" and \"nutrition in geriatrics","volume":"29","author":"Muscaritoli","year":"2010","journal-title":"Clin Nutr"},{"key":"10.1016\/j.clnu.2021.02.016_bib3","series-title":"Handbook of nutrition and diet in palliative care","article-title":"Anorexia in cancer: appetite, physiology, and beyond","author":"Molfino","year":"2019"},{"key":"10.1016\/j.clnu.2021.02.016_bib4","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.clnu.2009.05.013","article-title":"Decreased food intake is a risk factor for mortality in hospitalised patients: the NutritionDay survey 2006","volume":"28","author":"Hiesmayr","year":"2009","journal-title":"Clin Nutr"},{"key":"10.1016\/j.clnu.2021.02.016_bib5","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1093\/ajcn\/80.2.299","article-title":"Appetite and inflammation, nutrition, anemia, and clinical outcome in hemodialysis patients","volume":"80","author":"Kalantar-Zadeh","year":"2004","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.clnu.2021.02.016_bib6","doi-asserted-by":"crossref","first-page":"110952","DOI":"10.1016\/j.nut.2020.110952","article-title":"Plasma enterobacterial ClpB levels and ClpB- and \u03b1-MSH-reactive immunoglobulins in lung cancer patients with and without anorexia","volume":"78","author":"Molfino","year":"2020","journal-title":"Nutrition"},{"key":"10.1016\/j.clnu.2021.02.016_bib7","doi-asserted-by":"crossref","first-page":"4376","DOI":"10.1200\/JCO.2009.27.1916","article-title":"Prognostic factors in patients with advanced cancer: use of the patient-generated subjective global assessment in survival prediction","volume":"28","author":"Martin","year":"2010","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.clnu.2021.02.016_bib8","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1016\/S1470-2045(09)70200-1","article-title":"Baseline quality of life as a prognostic indicator of survival: a meta-analysis of individual patient data from EORTC clinical trials","volume":"10","author":"Quinten","year":"2009","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.clnu.2021.02.016_bib9","first-page":"103","article-title":"Validating appetite assessment tools among patients receiving hemodialysis","volume":"26","author":"Molfino","year":"2016","journal-title":"J\u00a0Ren Nutr"},{"key":"10.1016\/j.clnu.2021.02.016_bib10","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.clnu.2012.11.011","article-title":"Comparison of the performance of four different tools in diagnosing disease-associated anorexia and their relationship with nutritional, functional and clinical outcome measures in hospitalized patients","volume":"32","author":"Arezzo di Trifiletti","year":"2013","journal-title":"Clin Nutr"},{"key":"10.1016\/j.clnu.2021.02.016_bib11","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/j.appet.2008.10.010","article-title":"Assessment of subjective appetite sensations in hemodialysis patients. Agreement and feasibility between traditional paper and pen and a novel electronic appetite rating system","volume":"52","author":"Zabel","year":"2009","journal-title":"Appetite"},{"key":"10.1016\/j.clnu.2021.02.016_bib12","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1002\/jcsm.12156","article-title":"Cancer anorexia: hypothalamic activity and its association with inflammation and appetite-regulating peptides in lung cancer","volume":"8","author":"Molfino","year":"2017","journal-title":"J\u00a0Cachexia Sarcopenia Muscle"},{"key":"10.1016\/j.clnu.2021.02.016_bib13","doi-asserted-by":"crossref","first-page":"79884","DOI":"10.18632\/oncotarget.20168","article-title":"Prevalence of malnutrition in patients at first medical oncology visit: the PreMiO study","volume":"8","author":"Muscaritoli","year":"2017","journal-title":"Oncotarget"},{"key":"10.1016\/j.clnu.2021.02.016_bib14","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/0277-5379(86)90346-9","article-title":"Plasma tryptophan and anorexia in human cancer","volume":"22","author":"Rossi Fanelli","year":"1986","journal-title":"Eur J Cancer Clin Oncol"},{"key":"10.1016\/j.clnu.2021.02.016_bib15","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1038\/ncponc0112","article-title":"Therapy insight: cancer anorexia-cachexia syndrome-when all you can eat is yourself","volume":"2","author":"Laviano","year":"2005","journal-title":"Nat Clin Pract Oncol"},{"key":"10.1016\/j.clnu.2021.02.016_bib16","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1177\/014860719602000293","article-title":"Energy-enriched hospital food to improve energy intake in elderly patients","volume":"20","author":"Olin","year":"1996","journal-title":"JPEN - J Parenter Enter Nutr"},{"key":"10.1016\/j.clnu.2021.02.016_bib17","doi-asserted-by":"crossref","first-page":"3221","DOI":"10.1200\/JCO.2013.54.3926","article-title":"Efficacy of methylprednisolone on pain, fatigue, and appetite loss in patients with advanced cancer using opioids: a randomized, placebo-controlled, double-blind trial","volume":"32","author":"Paulsen","year":"2014","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.clnu.2021.02.016_bib18","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1080\/01635581.2018.1506488","article-title":"FAACT-anorexia cachexia scale: cutoff value for anorexia diagnosis in advanced non-small cell lung cancer patients","volume":"71","author":"Turcott","year":"2019","journal-title":"Nutr Canc"},{"key":"10.1016\/j.clnu.2021.02.016_bib19","first-page":"661","article-title":"The assessment of anorexia in patients with cancer: cut-off values for the FAACT-A\/CS and the VAS for appetite","volume":"24","author":"Blauwhoff-Buskermolen","year":"2016","journal-title":"Support Care Cancer"},{"key":"10.1016\/j.clnu.2021.02.016_bib20","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1200\/JCO.2014.59.9548","article-title":"Anorexia assessment in patients with cancer: a crucial issue to improve the outcome","volume":"33","author":"Molfino","year":"2015","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.clnu.2021.02.016_bib21","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1200\/JOP.2016.016832","article-title":"Cancer cachexia: beyond weight loss","volume":"12","author":"Bruggeman","year":"2016","journal-title":"J\u00a0Oncol Pract"},{"key":"10.1016\/j.clnu.2021.02.016_bib22","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1200\/JCO.2014.56.1894","article-title":"Diagnostic criteria for the classification of cancer-associated weight loss","volume":"33","author":"Martin","year":"2015","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.clnu.2021.02.016_bib23","doi-asserted-by":"crossref","first-page":"6240","DOI":"10.1200\/JCO.2005.06.866","article-title":"Prognostic factors in advanced cancer patients: evidence-based clinical recommendations-a study by the Steering Committee of the European Association for Palliative Care","volume":"23","author":"Maltoni","year":"2005","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.clnu.2021.02.016_bib24","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1016\/j.nut.2008.06.005","article-title":"NPY and brain monoamines in the pathogenesis of cancer anorexia","volume":"24","author":"Laviano","year":"2008","journal-title":"Nutrition"},{"key":"10.1016\/j.clnu.2021.02.016_bib25","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0224540","article-title":"Early recognition of anorexia through patient-generated assessment predicts survival in patients with oesophagogastric cancer","volume":"14","author":"Abraham","year":"2019","journal-title":"PloS One"},{"key":"10.1016\/j.clnu.2021.02.016_bib26","doi-asserted-by":"crossref","first-page":"2230","DOI":"10.1093\/annonc\/mdw420","article-title":"Perspectives of health care professionals on cancer cachexia: results from three global surveys","volume":"27","author":"Muscaritoli","year":"2016","journal-title":"Ann Oncol"},{"key":"10.1016\/j.clnu.2021.02.016_bib27","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1097\/SPC.0000000000000383","article-title":"Nutrition support for treating cancer-associated weight loss: an update","volume":"12","author":"Molfino","year":"2018","journal-title":"Curr Opin Support Palliat Care"},{"key":"10.1016\/j.clnu.2021.02.016_bib28","doi-asserted-by":"crossref","first-page":"2107","DOI":"10.1093\/annonc\/mdx271","article-title":"Forcing the vicious circle: sarcopenia increases toxicity, decreases response to chemotherapy and worsens with chemotherapy","volume":"28","author":"Bozzetti","year":"2017","journal-title":"Ann Oncol"},{"key":"10.1016\/j.clnu.2021.02.016_bib29","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1007\/s11739-013-0966-2","article-title":"Muscle depletion and the prediction of chemotherapy toxicity","volume":"8","author":"Muscaritoli","year":"2013","journal-title":"Intern Emerg Med"},{"key":"10.1016\/j.clnu.2021.02.016_bib30","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1111\/eci.12300","article-title":"Self-rated health, nutritional intake and mortality in adult hospitalized patients","volume":"44","author":"Lainscak","year":"2014","journal-title":"Eur J Clin Invest"},{"key":"10.1016\/j.clnu.2021.02.016_bib31","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1002\/jcsm.12391","article-title":"Is cachexia associated with chemotherapy toxicities in gastrointestinal cancer patients? A prospective study","volume":"10","author":"da Rocha","year":"2019","journal-title":"J\u00a0Cachexia Sarcopenia Muscle"}],"container-title":["Clinical Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S026156142100090X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S026156142100090X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T01:02:41Z","timestamp":1759366961000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S026156142100090X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6]]},"references-count":31,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["S026156142100090X"],"URL":"https:\/\/doi.org\/10.1016\/j.clnu.2021.02.016","relation":{},"ISSN":["0261-5614"],"issn-type":[{"value":"0261-5614","type":"print"}],"subject":[],"published":{"date-parts":[[2021,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cancer-associated anorexia: Validity and performance overtime of different appetite tools among patients at their first cancer diagnosis","name":"articletitle","label":"Article Title"},{"value":"Clinical Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clnu.2021.02.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.","name":"copyright","label":"Copyright"}]}}