{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T04:54:53Z","timestamp":1792040093302,"version":"4.4.0"},"reference-count":49,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,8,4]],"date-time":"2021-08-04T00:00:00Z","timestamp":1628035200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","clinicalnutritionjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Nutrition"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1016\/j.clnu.2021.07.035","type":"journal-article","created":{"date-parts":[[2021,8,8]],"date-time":"2021-08-08T04:42:41Z","timestamp":1628397761000},"page":"5238-5248","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":64,"title":["Bioelectrical impedance (BIA)-derived phase angle in adults with obesity: A systematic review"],"prefix":"10.1016","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3152-3130","authenticated-orcid":false,"given":"Olivia","family":"Di Vincenzo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio","family":"Marra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna Maria","family":"Sacco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabrizio","family":"Pasanisi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Scalfi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6 Pt A","key":"10.1016\/j.clnu.2021.07.035_bib1","first-page":"2045","article-title":"The combination of dynapenia and abdominal obesity as a risk factor for worse trajectories of IADL disability among older adults","volume":"37","author":"da Silva","year":"2018","journal-title":"Clin Nutr"},{"issue":"1","key":"10.1016\/j.clnu.2021.07.035_bib2","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1007\/s12603-017-0966-4","article-title":"Dynapenic abdominal obesity increases mortality risk among English and Brazilian older adults: a 10-year follow-up of the ELSA and SABE studies","volume":"22","author":"da Silva","year":"2018","journal-title":"J\u00a0Nutr Health Aging"},{"issue":"4","key":"10.1016\/j.clnu.2021.07.035_bib3","doi-asserted-by":"crossref","first-page":"303.e13","DOI":"10.1016\/j.jamda.2013.12.008","article-title":"Exploring the role of muscle mass, obesity, and age in the relationship between muscle quality and physical function","volume":"15","author":"Barbat-Artigas","year":"2014","journal-title":"J\u00a0Am Med Dir Assoc"},{"issue":"1","key":"10.1016\/j.clnu.2021.07.035_bib4","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/2046-2395-3-9","article-title":"It is not just muscle mass: a review of muscle quality, composition and metabolism during ageing as determinants of muscle function and mobility in later life","volume":"3","author":"McGregor","year":"2014","journal-title":"Longev Heal"},{"issue":"1","key":"10.1016\/j.clnu.2021.07.035_bib5","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1152\/japplphysiol.00739.2020","article-title":"Current perspectives on obesity and skeletal muscle contractile function in older adults","volume":"130","author":"Straight","year":"2021","journal-title":"J\u00a0Appl Physiol"},{"issue":"Pt 13","key":"10.1016\/j.clnu.2021.07.035_bib6","article-title":"The effects of obesity on skeletal muscle contractile function","volume":"221","author":"Tallis","year":"2018","journal-title":"J\u00a0Exp Biol"},{"issue":"1","key":"10.1016\/j.clnu.2021.07.035_bib7","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1186\/s12891-020-03228-y","article-title":"Obesity-associated poor muscle quality: prevalence and association with age, sex, and body mass index","volume":"21","author":"Valenzuela","year":"2020","journal-title":"BMC Muscoskel Disord"},{"issue":"7","key":"10.1016\/j.clnu.2021.07.035_bib8","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1038\/ijo.2012.181","article-title":"Increased insulin receptor substrate 2 expression is associated with steatohepatitis and altered lipid metabolism in obese subjects","volume":"37","author":"Rametta","year":"2013","journal-title":"Int J Obes"},{"issue":"1","key":"10.1016\/j.clnu.2021.07.035_bib9","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1093\/ageing\/afy169","article-title":"Sarcopenia: revised European consensus on definition and diagnosis","volume":"48","author":"Cruz-Jentoft","year":"2019","journal-title":"Age Ageing"},{"issue":"5","key":"10.1016\/j.clnu.2021.07.035_bib10","doi-asserted-by":"crossref","first-page":"1851","DOI":"10.1152\/japplphysiol.00246.2003","article-title":"Age-associated changes in skeletal muscles and their effect on mobility: an operational diagnosis of sarcopenia","volume":"95","author":"Lauretani","year":"2003","journal-title":"J\u00a0Appl Physiol"},{"issue":"9","key":"10.1016\/j.clnu.2021.07.035_bib11","first-page":"1180","article-title":"Electrical properties assessed by bioelectrical impedance spectroscopy as biomarkers of age-related loss of skeletal muscle quantity and quality","volume":"72","author":"Yamada","year":"2001","journal-title":"J\u00a0Gerontol Series A: Biolog Sci Med Sci"},{"issue":"9","key":"10.1016\/j.clnu.2021.07.035_bib12","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1038\/s41574-018-0062-9","article-title":"Sarcopenic obesity in older adults: aetiology, epidemiology and treatment strategies","volume":"14","author":"Batsis","year":"2018","journal-title":"Nat Rev Endocrinol"},{"key":"10.1016\/j.clnu.2021.07.035_bib13","first-page":"11","article-title":"Health consequences of sarcopenic obesity: a narrative review","author":"Roh","year":"2020","journal-title":"Front Endocrinol"},{"issue":"1","key":"10.1016\/j.clnu.2021.07.035_bib14","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/s12603-012-0004-5","article-title":"How to assess functional status: a new muscle quality index","volume":"16","author":"Barbat-Artigas","year":"2012","journal-title":"J\u00a0Nutr Health Aging"},{"issue":"2","key":"10.1016\/j.clnu.2021.07.035_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.jamda.2014.10.024","article-title":"The bioimpedance phase angle predicts low muscle strength, impaired quality of life, and increased mortality in old patients with cancer","volume":"16","author":"Norman","year":"2015","journal-title":"J\u00a0Am Med Dir Assoc"},{"issue":"1","key":"10.1016\/j.clnu.2021.07.035_bib16","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1002\/jcsm.12353","article-title":"Improved strength prediction combining clinically available measures of skeletal muscle mass and quality","volume":"10","author":"Bourgeois","year":"2019","journal-title":"Journal of Cachexia, Sarcopenia and Muscle"},{"issue":"5","key":"10.1016\/j.clnu.2021.07.035_bib17","first-page":"330","article-title":"Assessment of adult malnutrition and prognosis with bioelectrical impedance analysis: phase angle and impedance ratio","volume":"20","author":"Lukaski","year":"2017","journal-title":"Curr Opin Clin Nutr Metab Care"},{"issue":"4","key":"10.1016\/j.clnu.2021.07.035_bib18","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1177\/0148607106030004309","article-title":"Phase Angle from bioelectrical impedance analysis: population reference values by age, sex, and body mass index","volume":"30","author":"Bosy-Westphal","year":"2006","journal-title":"J\u00a0Parenter Enter Nutr"},{"issue":"11","key":"10.1016\/j.clnu.2021.07.035_bib19","doi-asserted-by":"crossref","first-page":"1336","DOI":"10.1038\/ejcn.2017.147","article-title":"Raw BIA variables are predictors of muscle strength in patients with chronic obstructive pulmonary disease","volume":"71","author":"de Blasio","year":"2017","journal-title":"Eur J Clin Nutr"},{"issue":"1","key":"10.1016\/j.clnu.2021.07.035_bib20","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1186\/s12970-019-0319-2","article-title":"Bioelectrical impedance phase angle in sport: a systematic review","volume":"16","author":"Di Vincenzo","year":"2019","journal-title":"J\u00a0Int Soc Sports Nutr"},{"issue":"5","key":"10.1016\/j.clnu.2021.07.035_bib21","doi-asserted-by":"crossref","first-page":"3052","DOI":"10.1016\/j.clnu.2020.10.048","article-title":"Bioelectrical impedance analysis (BIA) -derived phase angle in sarcopenia: a systematic review","volume":"40","author":"Di Vincenzo","year":"2021","journal-title":"Clin Nutr"},{"issue":"3","key":"10.1016\/j.clnu.2021.07.035_bib22","doi-asserted-by":"crossref","first-page":"612","DOI":"10.3945\/ajcn.2010.29215","article-title":"Cutoff percentiles of bioelectrical phase angle predict functionality, quality of life, and mortality in patients with cancer","volume":"92","author":"Norman","year":"2010","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.clnu.2021.07.035_bib23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.rmed.2017.11.006","article-title":"Malnutrition and sarcopenia assessment in patients with chronic obstructive pulmonary disease according to international diagnostic criteria, and evaluation of raw BIA variables","volume":"134","author":"de Blasio","year":"2018","journal-title":"Respir Med"},{"issue":"2","key":"10.1016\/j.clnu.2021.07.035_bib24","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1177\/0884533617728487","article-title":"Bioelectrical impedance analysis-derived measurements in chronic hepatitis C: clinical relevance of fat-free mass and phase Angle evaluation","volume":"33","author":"Bering","year":"2018","journal-title":"Nutr Clin Pract"},{"issue":"7","key":"10.1016\/j.clnu.2021.07.035_bib25","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1371\/journal.pmed.1000097","article-title":"Preferred reporting Items for systematic reviews and meta-analyses: the PRISMA statement","volume":"6","author":"Moher","year":"2009","journal-title":"PLoS Med"},{"key":"10.1016\/j.clnu.2021.07.035_bib26","series-title":"Quality assessment tool for observational cohort and cross-sectional studies","year":"2014"},{"key":"10.1016\/j.clnu.2021.07.035_bib27","doi-asserted-by":"crossref","first-page":"s139","DOI":"10.1007\/s00592-003-0047-5","article-title":"The prediction of basal metabolic rate in young adult, severely obese patients using single-frequency bioimpedance analysis","volume":"40","author":"Marra","year":"2003","journal-title":"Acta Diabetol"},{"issue":"6","key":"10.1016\/j.clnu.2021.07.035_bib28","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1007\/BF03344144","article-title":"Growth hormone status in morbidly obese subjects and correlation with body composition","volume":"29","author":"Savastano","year":"2006","journal-title":"J\u00a0Endocrinol Invest"},{"issue":"1","key":"10.1016\/j.clnu.2021.07.035_bib29","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1186\/1129-2377-14-75","article-title":"Cardiovascular disease risk in women with migraine","volume":"14","author":"Rockett","year":"2013","journal-title":"J\u00a0Headache Pain"},{"issue":"6","key":"10.1016\/j.clnu.2021.07.035_bib30","first-page":"1130","article-title":"Phase angle and metabolic parameters in severely obese patients","volume":"37","author":"Curvello-Silva","year":"2020","journal-title":"Nutr Hosp"},{"key":"10.1016\/j.clnu.2021.07.035_bib31","doi-asserted-by":"crossref","first-page":"113104","DOI":"10.1016\/j.physbeh.2020.113104","article-title":"Phase angle associated with different indicators of health-related physical fitness in adults with obesity","volume":"225","author":"Streb","year":"2020","journal-title":"Physiol Behav"},{"key":"10.1016\/j.clnu.2021.07.035_bib32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2012\/208953","article-title":"Impact of the\u00a0\u2212174 G > C IL-6 polymorphism on bioelectrical parameters in obese subjects after laparoscopic adjustable gastric banding","volume":"2012","author":"Di Renzo","year":"2012","journal-title":"Journal of Obesity"},{"issue":"12","key":"10.1016\/j.clnu.2021.07.035_bib33","doi-asserted-by":"crossref","first-page":"1957","DOI":"10.1007\/s11695-013-1036-6","article-title":"Laparoscopic sleeve gastrectomy compared to a multidisciplinary weight loss program for obesity\u2014effects on body composition and protein status","volume":"23","author":"Friedrich","year":"2013","journal-title":"Obes Surg"},{"issue":"3","key":"10.1016\/j.clnu.2021.07.035_bib34","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1007\/s11695-016-2315-9","article-title":"The phase Angle of the bioelectrical impedance analysis as predictor of post-bariatric weight loss outcome","volume":"27","author":"Vassilev","year":"2017","journal-title":"Obes Surg"},{"issue":"2","key":"10.1016\/j.clnu.2021.07.035_bib35","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1007\/s11695-018-3528-x","article-title":"Changes in body composition, dietary intake, and substrate oxidation in patients underwent laparoscopic roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy: a comparative prospective study","volume":"29","author":"Golzarand","year":"2019","journal-title":"Obes Surg"},{"key":"10.1016\/j.clnu.2021.07.035_bib36","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.clnesp.2019.05.018","article-title":"Bioimpedance phase angle is associated with serum transthyretin but not with prognostic inflammatory and nutritional index during follow-up of women submitted to bariatric surgery","volume":"33","author":"Koehler","year":"2019","journal-title":"Clinical Nutrition ESPEN"},{"issue":"1","key":"10.1016\/j.clnu.2021.07.035_bib37","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1007\/s11695-020-04869-7","article-title":"Handgrip strength and phase Angle predict outcome after bariatric surgery","volume":"31","author":"Gerken","year":"2021","journal-title":"Obes Surg"},{"issue":"4","key":"10.1016\/j.clnu.2021.07.035_bib38","doi-asserted-by":"crossref","first-page":"1680","DOI":"10.1007\/s11695-020-05179-8","article-title":"Roux-en-Y gastric bypass and sleeve gastrectomy differently affect oxidative damage markers and their correlations with body parameters","volume":"31","author":"Ven\u00e2ncio","year":"2021","journal-title":"Obes Surg"},{"issue":"9","key":"10.1016\/j.clnu.2021.07.035_bib39","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1055\/s-0032-1306284","article-title":"Whole body vibration added to endurance training in obese women - a pilot study","volume":"33","author":"Wilms","year":"2012","journal-title":"Int J Sports Med"},{"issue":"4","key":"10.1016\/j.clnu.2021.07.035_bib40","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.3390\/ijerph17041163","article-title":"Comparison of the effect of different resistance training frequencies on phase Angle and handgrip strength in obese women: a randomized controlled trial","volume":"17","author":"Toselli","year":"2020","journal-title":"IJERPH"},{"key":"10.1016\/j.clnu.2021.07.035_bib41","series-title":"Relation of phase angle tertiles with blood adipocytokines levels, insulin resistance and cardiovascular risk factors in obese women patients","first-page":"521","author":"De Luis","year":"2010"},{"issue":"11","key":"10.1016\/j.clnu.2021.07.035_bib42","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.4254\/wjh.v12.i11.1004","article-title":"Phase angle and non-alcoholic fatty liver disease before and after bariatric surgery","volume":"12","author":"Teixeira","year":"2020","journal-title":"WJH"},{"issue":"4","key":"10.1016\/j.clnu.2021.07.035_bib43","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1007\/s005920050135","article-title":"Bioelectrical characteristics of type 1 and type 2 diabetic subjects with reference to body water compartments","volume":"35","author":"Buscemi","year":"1998","journal-title":"Acta Diabetol"},{"issue":"8","key":"10.1016\/j.clnu.2021.07.035_bib44","doi-asserted-by":"crossref","first-page":"1747","DOI":"10.3390\/nu11081747","article-title":"Phase Angle: a possible biomarker to quantify inflammation in subjects with obesity and 25(OH)D deficiency","volume":"11","author":"Barrea","year":"2019","journal-title":"Nutrients"},{"issue":"2","key":"10.1016\/j.clnu.2021.07.035_bib45","doi-asserted-by":"crossref","first-page":"216","DOI":"10.3390\/nu11020216","article-title":"Are raw BIA variables useful for predicting resting energy expenditure in adults with obesity?","volume":"11","author":"Marra","year":"2019","journal-title":"Nutrients"},{"issue":"2","key":"10.1016\/j.clnu.2021.07.035_bib46","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/S0939-4753(03)80021-2","article-title":"Impedance vector distribution by body mass index and conventional bioelectrical impedance analysis in obese women","volume":"13","author":"Guida","year":"2003","journal-title":"Nutr Metabol Cardiovasc Dis"},{"key":"10.1016\/j.clnu.2021.07.035_bib47","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1093\/ajcn\/82.1.49","article-title":"Bioelectrical impedance analysis: population reference values for phase angle by age and sex","volume":"82","author":"Barbosa Silva","year":"2005","journal-title":"Am J Clin Nutr"},{"issue":"7\u20138","key":"10.1016\/j.clnu.2021.07.035_bib48","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1016\/S0899-9007(01)00555-X","article-title":"Fat-free and fat mass percentiles in 5225 healthy subjects aged 15 to 98 years","volume":"17","author":"Kyle","year":"2001","journal-title":"Nutrition"},{"issue":"4","key":"10.1016\/j.clnu.2021.07.035_bib49","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.1016\/j.clnu.2020.10.001","article-title":"Long-term effect of bariatric surgery on body composition in patients with morbid obesity: a systematic review and meta-analysis","volume":"40","author":"Haghighat","year":"2001","journal-title":"Clin Nutr"}],"container-title":["Clinical Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S026156142100371X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S026156142100371X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T01:01:51Z","timestamp":1759366911000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S026156142100371X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":49,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["S026156142100371X"],"URL":"https:\/\/doi.org\/10.1016\/j.clnu.2021.07.035","relation":{},"ISSN":["0261-5614"],"issn-type":[{"value":"0261-5614","type":"print"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Bioelectrical impedance (BIA)-derived phase angle in adults with obesity: A systematic review","name":"articletitle","label":"Article Title"},{"value":"Clinical Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clnu.2021.07.035","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Author(s). Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}