{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T21:06:25Z","timestamp":1790715985076,"version":"4.1.0"},"reference-count":33,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T00:00:00Z","timestamp":1648512000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","clinicalnutritionjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Nutrition"],"published-print":{"date-parts":[[2022,5]]},"DOI":"10.1016\/j.clnu.2022.03.026","type":"journal-article","created":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T04:59:35Z","timestamp":1648702775000},"page":"1093-1101","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["An in-line digestive cartridge increases enteral fat and vitamin absorption in a porcine model of short bowel syndrome"],"prefix":"10.1016","volume":"41","author":[{"given":"S.T.","family":"Tsikis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.C.","family":"Fligor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.D.","family":"Secor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.J.","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.D.","family":"Mitchell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Loring","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"First","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.P.","family":"Nedder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.M.","family":"Grammer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Pattison","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.M.","family":"Gura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Puder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.clnu.2022.03.026_bib1","doi-asserted-by":"crossref","first-page":"S5","DOI":"10.1053\/j.gastro.2005.07.063","article-title":"Etiology and initial management of short bowel syndrome","volume":"130","author":"Buchman","year":"2006","journal-title":"Gastroenterology"},{"key":"10.1016\/j.clnu.2022.03.026_bib2","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1002\/jpen.1667","article-title":"Risk factors of ambulatory central line-associated bloodstream infection in pediatric short bowel syndrome","volume":"44","author":"Seddik","year":"2020","journal-title":"J\u00a0Parenter Enteral Nutr"},{"key":"10.1016\/j.clnu.2022.03.026_bib3","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1097\/MPG.0b013e31820e8396","article-title":"Risk factors for parenteral nutrition-associated liver disease following surgical therapy for necrotizing enterocolitis: a Glaser Pediatric Research Network Study [corrected]","volume":"52","author":"Duro","year":"2011","journal-title":"J\u00a0Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.clnu.2022.03.026_bib4","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1016\/j.jpedsurg.2004.01.036","article-title":"Neonatal short bowel syndrome: population-based estimates of incidence and mortality rates","volume":"39","author":"Wales","year":"2004","journal-title":"J\u00a0Pediatr Surg"},{"key":"10.1016\/j.clnu.2022.03.026_bib5","doi-asserted-by":"crossref","first-page":"663","DOI":"10.3945\/ajcn.116.137083","article-title":"Predictors of failure of fish-oil therapy for intestinal failure-associated liver disease in children","volume":"104","author":"Nandivada","year":"2016","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.clnu.2022.03.026_bib6","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1016\/j.jpedsurg.2013.02.070","article-title":"The impact of multi-disciplinary intestinal rehabilitation programs on the outcome of pediatric patients with intestinal failure: a systematic review and meta-analysis","volume":"48","author":"Stanger","year":"2013","journal-title":"J\u00a0Pediatr Surg"},{"key":"10.1016\/j.clnu.2022.03.026_bib7","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.nutres.2017.02.004","article-title":"Use of a novel docosahexaenoic acid formulation vs control in a neonatal porcine model of short bowel syndrome leads to greater intestinal absorption and higher systemic levels of DHA","volume":"39","author":"Martin","year":"2017","journal-title":"Nutr Res"},{"key":"10.1016\/j.clnu.2022.03.026_bib8","doi-asserted-by":"crossref","first-page":"229","DOI":"10.4103\/1319-3767.82573","article-title":"Short bowel syndrome: a review of management options","volume":"17","author":"Seetharam","year":"2011","journal-title":"Saudi J Gastroenterol"},{"key":"10.1016\/j.clnu.2022.03.026_bib9","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1038\/pr.2013.44","article-title":"Role of glucagon-like peptide-2 deficiency in neonatal short-bowel syndrome using neonatal piglets","volume":"73","author":"Hua","year":"2013","journal-title":"Pediatr Res"},{"key":"10.1016\/j.clnu.2022.03.026_bib10","doi-asserted-by":"crossref","first-page":"G390","DOI":"10.1152\/ajpgi.00281.2016","article-title":"Synergy of glucagon-like peptide-2 and epidermal growth factor coadministration on intestinal adaptation in neonatal piglets with short bowel syndrome","volume":"312","author":"Lim","year":"2017","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.1016\/j.clnu.2022.03.026_bib11","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1002\/jpen.1500","article-title":"Novel long-acting GLP-2 analogue, FE 203799 (Apraglutide), enhances adaptation and linear intestinal growth in a neonatal piglet model of short bowel syndrome with total resection of the ileum","volume":"43","author":"Slim","year":"2019","journal-title":"J\u00a0Parenter Enteral Nutr"},{"key":"10.1016\/j.clnu.2022.03.026_bib12","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1177\/0148607114554621","article-title":"Emerging piglet models of neonatal short bowel syndrome","volume":"39","author":"Lim","year":"2015","journal-title":"J\u00a0Parenter Enteral Nutr"},{"key":"10.1016\/j.clnu.2022.03.026_bib13","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.jss.2022.01.004","article-title":"Outcomes and perioperative nutritional management in a porcine model of short bowel syndrome","volume":"274","author":"Tsikis","year":"2022","journal-title":"J\u00a0Surg Res"},{"key":"10.1016\/j.clnu.2022.03.026_bib14","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1097\/MPG.0000000000001617","article-title":"Increased fat absorption from enteral formula through an in-line digestive cartridge in patients with cystic fibrosis","volume":"65","author":"Freedman","year":"2017","journal-title":"J\u00a0Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.clnu.2022.03.026_bib15","series-title":"Compatible formulas and pumps","year":"2021"},{"key":"10.1016\/j.clnu.2022.03.026_bib16","doi-asserted-by":"crossref","first-page":"306","DOI":"10.4292\/wjgpt.v7.i2.306","article-title":"Nutritional and health benefits of semi-elemental diets: a comprehensive summary of the literature","volume":"7","author":"Alexander","year":"2016","journal-title":"World J Gastrointest Pharmacol Ther"},{"key":"10.1016\/j.clnu.2022.03.026_bib17","series-title":"Guide for the Care and Use of Laboratory Animals","article-title":"Committee for the update of the guide for the care and use of laboratory animals IfLAR, division on earth and life studies, & National Research Council","year":"2010"},{"key":"10.1016\/j.clnu.2022.03.026_bib19","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1002\/jpen.1677","article-title":"Trends of INR and fecal excretion of vitamin K during cholestasis reversal: implications in the treatment of neonates with intestinal failure-associated liver disease","volume":"44","author":"Dao","year":"2020","journal-title":"J\u00a0Parenter Enteral Nutr"},{"key":"10.1016\/j.clnu.2022.03.026_bib20","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/j.jacl.2013.05.001","article-title":"Comparative effects of an acute dose of fish oil on omega-3 fatty acid levels in red blood cells versus plasma: implications for clinical utility","volume":"7","author":"Harris","year":"2013","journal-title":"J\u00a0Clin Lipidol"},{"key":"10.1016\/j.clnu.2022.03.026_bib21","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1309\/0T2W-NN7F-7T8Q-5N8C","article-title":"A\u00a0new method of quantitative fecal fat microscopy and its correlation with chemically measured fecal fat output","volume":"113","author":"Fine","year":"2000","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.clnu.2022.03.026_bib22","first-page":"47","article-title":"Coefficients of fat and nitrogen absorption in healthy subjects and individuals with cystic fibrosis","volume":"12","author":"Borowitz","year":"2007","journal-title":"J\u00a0Pediatr Pharmacol Ther"},{"key":"10.1016\/j.clnu.2022.03.026_bib23","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/S0021-9258(18)57092-7","article-title":"Rapid method for the determination of fat in feces","volume":"177","author":"Van De Kamer","year":"1949","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.clnu.2022.03.026_bib24","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1097\/MPG.0b013e318180af4f","article-title":"Exocrine pancreatic function testing in patients with cystic fibrosis and pancreatic sufficiency: a correlation study","volume":"48","author":"Weintraub","year":"2009","journal-title":"J\u00a0Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.clnu.2022.03.026_bib25","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.1136\/gut.2004.061440","article-title":"Teduglutide (ALX-0600), a dipeptidyl peptidase IV resistant glucagon-like peptide 2 analogue, improves intestinal function in short bowel syndrome patients","volume":"54","author":"Jeppesen","year":"2005","journal-title":"Gut"},{"key":"10.1016\/j.clnu.2022.03.026_bib26","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1177\/0148607115602891","article-title":"Teduglutide-stimulated intestinal adaptation is complemented and synergistically enhanced by partial enteral nutrition in a neonatal piglet model of short bowel syndrome","volume":"41","author":"Naberhuis","year":"2017","journal-title":"J\u00a0Parenter Enteral Nutr"},{"key":"10.1016\/j.clnu.2022.03.026_bib27","first-page":"27","article-title":"Fat-soluble vitamins: clinical indications and current challenges for chromatographic measurement","volume":"37","author":"Albahrani","year":"2016","journal-title":"Clin Biochem Rev"},{"key":"10.1016\/j.clnu.2022.03.026_bib28","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.foodchem.2014.09.021","article-title":"Fat-soluble vitamin intestinal absorption: absorption sites in the intestine and interactions for absorption","volume":"172","author":"Goncalves","year":"2015","journal-title":"Food Chem"},{"key":"10.1016\/j.clnu.2022.03.026_bib29","doi-asserted-by":"crossref","DOI":"10.3390\/nu8110676","article-title":"Molecular basis for vitamin A uptake and storage in vertebrates","volume":"8","author":"Chelstowska","year":"2016","journal-title":"Nutrients"},{"key":"10.1016\/j.clnu.2022.03.026_bib30","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.jpeds.2010.12.049","article-title":"High prevalence of multiple micronutrient deficiencies in children with intestinal failure: a longitudinal study","volume":"159","author":"Yang","year":"2011","journal-title":"J\u00a0Pediatr"},{"key":"10.1016\/j.clnu.2022.03.026_bib31","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/j.clnu.2017.02.014","article-title":"Bone health of children with intestinal failure measured by dual energy X-ray absorptiometry and digital X-ray radiogrammetry","volume":"37","author":"Neelis","year":"2018","journal-title":"Clin Nutr"},{"key":"10.1016\/j.clnu.2022.03.026_bib32","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1002\/jpen.1011","article-title":"Single-center experience with the use of teduglutide in adult patients with short bowel syndrome","volume":"42","author":"Lam","year":"2018","journal-title":"J\u00a0Parenter Enteral Nutr"},{"key":"10.1016\/j.clnu.2022.03.026_bib33","first-page":"S220","article-title":"Options for addressing exocrine pancreatic insufficiency in patients receiving enteral nutrition supplementation","volume":"23","author":"Freedman","year":"2017","journal-title":"Am J Manag Care"},{"key":"10.1016\/j.clnu.2022.03.026_bib34","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1097\/MPG.0000000000002110","article-title":"Absorption and safety with sustained use of RELiZORB evaluation (ASSURE) study in patients with cystic fibrosis receiving enteral feeding","volume":"67","author":"Stevens","year":"2018","journal-title":"J\u00a0Pediatr Gastroenterol Nutr"}],"container-title":["Clinical Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0261561422001078?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0261561422001078?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T01:06:01Z","timestamp":1759367161000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0261561422001078"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":33,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["S0261561422001078"],"URL":"https:\/\/doi.org\/10.1016\/j.clnu.2022.03.026","relation":{},"ISSN":["0261-5614"],"issn-type":[{"value":"0261-5614","type":"print"}],"subject":[],"published":{"date-parts":[[2022,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"An in-line digestive cartridge increases enteral fat and vitamin absorption in a porcine model of short bowel syndrome","name":"articletitle","label":"Article Title"},{"value":"Clinical Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clnu.2022.03.026","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Author(s). Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}