{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T11:34:48Z","timestamp":1789731288094,"version":"4.0.1"},"reference-count":74,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100004901","name":"FAPEMIG","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004901","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012211","name":"Chinese Diabetes Society","doi-asserted-by":"publisher","award":["APQ-00369-17"],"award-info":[{"award-number":["APQ-00369-17"]}],"id":[{"id":"10.13039\/501100012211","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003545","name":"Minist\u00e9rio da Ci\u00eancia, Tecnologia e Inova\u00e7\u00e3o","doi-asserted-by":"publisher","award":["404770\/2021-5"],"award-info":[{"award-number":["404770\/2021-5"]}],"id":[{"id":"10.13039\/501100003545","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003545","name":"Minist\u00e9rio da Ci\u00eancia, Tecnologia e Inova\u00e7\u00e3o","doi-asserted-by":"publisher","award":["CDS-APQ-01808-22"],"award-info":[{"award-number":["CDS-APQ-01808-22"]}],"id":[{"id":"10.13039\/501100003545","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002701","name":"Ministry of Education","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002701","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"CNPq","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"CAPES","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","clinicalnutritionjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Nutrition"],"published-print":{"date-parts":[[2025,2]]},"DOI":"10.1016\/j.clnu.2024.12.017","type":"journal-article","created":{"date-parts":[[2024,12,19]],"date-time":"2024-12-19T17:38:12Z","timestamp":1734629892000},"page":"22-30","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Adiposity and inflammation markers explain mostly part of the plasma zonulin variation in Brazilian adults with overweight\/obesity: A cross-sectional analysis from Brazilian nuts study"],"prefix":"10.1016","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2658-6519","authenticated-orcid":false,"given":"Madalena Geralda Cupertino","family":"Ribeiro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Claudia Pelissari","family":"Kravchychyn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josefina","family":"Bressan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helen Hermana Miranda","family":"Hermsdorff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/j.clnu.2024.12.017_bib1","doi-asserted-by":"crossref","DOI":"10.3390\/cells9081909","article-title":"The intestinal barrier and current techniques for the assessment of gut permeability","volume":"9","author":"Schoultz","year":"2020","journal-title":"Cells."},{"issue":"2","key":"10.1016\/j.clnu.2024.12.017_bib2","first-page":"795","article-title":"Intestinal permeability in physiological and pathological conditions: major determinants and assessment modalities","volume":"23","author":"Graziani","year":"2019","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"10.1016\/j.clnu.2024.12.017_bib3","series-title":"Intestinal permeability assessment using lactulose and mannitol in celiac disease. Em: methods in Cell Biology [Internet]","author":"Velasco","year":"2023"},{"issue":"9","key":"10.1016\/j.clnu.2024.12.017_bib4","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1080\/17474124.2017.1343143","article-title":"The intestinal barrier: a fundamental role in health and disease","volume":"11","author":"Vancamelbeke","year":"2017","journal-title":"Expet Rev Gastroenterol Hepatol"},{"issue":"1","key":"10.1016\/j.clnu.2024.12.017_bib5","article-title":"Regulation of the intestinal barrier by nutrients: the role of tight junctions","volume":"91","author":"Suzuki","year":"2020","journal-title":"Anim Sci J Nihon Chikusan Gakkaiho"},{"issue":"1","key":"10.1016\/j.clnu.2024.12.017_bib6","first-page":"3","article-title":"Obesity, adipose tissue, and bariatric surgery","volume":"77","author":"Frigolet","year":"2020","journal-title":"Bol Med Hosp Infant Mex"},{"issue":"8","key":"10.1016\/j.clnu.2024.12.017_bib7","doi-asserted-by":"crossref","first-page":"2670","DOI":"10.1007\/s11695-019-03952-y","article-title":"Obesity surgery and anesthesiology risks: a Review of key concepts and related physiology","volume":"29","author":"Pouwels","year":"2019","journal-title":"Obes Surg"},{"issue":"6","key":"10.1016\/j.clnu.2024.12.017_bib8","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1161\/CIRCRESAHA.119.312321","article-title":"Obesity, hypertension, and cardiac dysfunction: novel roles of immunometabolism in macrophage activation and inflammation","volume":"126","author":"Mouton","year":"2020","journal-title":"Circ Res"},{"issue":"2","key":"10.1016\/j.clnu.2024.12.017_bib9","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1002\/path.5134","article-title":"Increased jejunal permeability in human obesity is revealed by a lipid challenge and is linked to inflammation and type 2 diabetes","volume":"246","author":"Genser","year":"2018","journal-title":"J Pathol"},{"issue":"8","key":"10.1016\/j.clnu.2024.12.017_bib10","doi-asserted-by":"crossref","first-page":"1912","DOI":"10.3390\/ijms20081912","article-title":"Curcumin and intestinal inflammatory diseases: molecular mechanisms of protection","volume":"20","author":"Burge","year":"2019","journal-title":"Int J Mol Sci"},{"issue":"1","key":"10.1016\/j.clnu.2024.12.017_bib11","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1111\/nyas.13360","article-title":"Intestinal epithelial claudins: expression and regulation in homeostasis and inflammation","volume":"1397","author":"Garcia-Hernandez","year":"2017","journal-title":"Ann N Y Acad Sci"},{"issue":"22","key":"10.1016\/j.clnu.2024.12.017_bib12","doi-asserted-by":"crossref","first-page":"2387","DOI":"10.1042\/CS20180410","article-title":"Impact of the gut microbiome in cardiovascular and autoimmune diseases","volume":"132","author":"Weis","year":"2018","journal-title":"Clin Sci Lond Engl"},{"issue":"3","key":"10.1016\/j.clnu.2024.12.017_bib13","doi-asserted-by":"crossref","first-page":"R192","DOI":"10.1152\/ajpregu.00270.2021","article-title":"High-altitude exposures and intestinal barrier dysfunction","volume":"322","author":"McKenna","year":"2022","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"issue":"10","key":"10.1016\/j.clnu.2024.12.017_bib14","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1016\/j.cgh.2012.08.012","article-title":"Intestinal permeability and its regulation by zonulin: diagnostic and therapeutic implications","volume":"10","author":"Fasano","year":"2012","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"24","key":"10.1016\/j.clnu.2024.12.017_bib15","doi-asserted-by":"crossref","first-page":"4435","DOI":"10.1242\/jcs.113.24.4435","article-title":"Human zonulin, a potential modulator of intestinal tight junctions","volume":"113","author":"Wang","year":"2000","journal-title":"J Cell Sci"},{"key":"10.1016\/j.clnu.2024.12.017_bib16","doi-asserted-by":"crossref","DOI":"10.12688\/f1000research.20510.1","article-title":"All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic inflammatory diseases","volume":"9","author":"Fasano","year":"2020","journal-title":"F1000Research"},{"issue":"9","key":"10.1016\/j.clnu.2024.12.017_bib17","first-page":"409","article-title":"Effect of diet on the low-grade and chronic inflammation associated with obesity and metabolic syndrome","volume":"55","author":"Hermsdorff","year":"2008","journal-title":"Endocrinol Nutr Organo Soc Espanola Endocrinol Nutr"},{"issue":"9","key":"10.1016\/j.clnu.2024.12.017_bib18","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.3390\/cells11091424","article-title":"New insights into adipose tissue macrophages in obesity and insulin resistance","volume":"11","author":"Cai","year":"2022","journal-title":"Cells"},{"issue":"14","key":"10.1016\/j.clnu.2024.12.017_bib19","doi-asserted-by":"crossref","first-page":"7613","DOI":"10.3390\/ijms22147613","article-title":"Leaky gut: effect of dietary fiber and fats on microbiome and intestinal barrier","volume":"22","author":"Usuda","year":"2021","journal-title":"Int J Mol Sci"},{"issue":"2","key":"10.1016\/j.clnu.2024.12.017_bib20","doi-asserted-by":"crossref","first-page":"379","DOI":"10.3390\/ijms21020379","article-title":"Recent advances in lipopolysaccharide recognition systems","volume":"21","author":"Mazgaeen","year":"2020","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.clnu.2024.12.017_bib21","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1186\/s40104-023-00835-2","article-title":"Yeast hydrolysate attenuates lipopolysaccharide-induced inflammatory responses and intestinal barrier damage in weaned piglets","volume":"14","author":"Fu","year":"2023","journal-title":"J Anim Sci Biotechnol"},{"issue":"5","key":"10.1016\/j.clnu.2024.12.017_bib22","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1007\/s11739-023-03262-3","article-title":"Are gut dysbiosis, barrier disruption, and endotoxemia related to adipose tissue dysfunction in metabolic disorders? Overview of the mechanisms involved","volume":"18","author":"Rosendo-Silva","year":"2023","journal-title":"Intern Emerg Med"},{"issue":"5","key":"10.1016\/j.clnu.2024.12.017_bib23","doi-asserted-by":"crossref","first-page":"2041","DOI":"10.1128\/iai.63.5.2041-2046.1995","article-title":"Role for circulating lipoproteins in protection from endotoxin toxicity","volume":"63","author":"Feingold","year":"1995","journal-title":"Infect Immun"},{"key":"10.1016\/j.clnu.2024.12.017_bib24","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.cca.2018.03.005","article-title":"Zonulin level, a marker of intestinal permeability, is increased in association with liver enzymes in young adolescents","volume":"481","author":"Kim","year":"2018","journal-title":"Clin Chim Acta Int J Clin Chem"},{"issue":"1","key":"10.1016\/j.clnu.2024.12.017_bib25","doi-asserted-by":"crossref","first-page":"24","DOI":"10.3390\/biom9010024","article-title":"Plasma zonulin levels as a non-invasive biomarker of intestinal permeability in women with gestational diabetes mellitus","volume":"9","author":"Demir","year":"2019","journal-title":"Biomolecules"},{"issue":"5","key":"10.1016\/j.clnu.2024.12.017_bib26","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0037160","article-title":"Circulating zonulin, a marker of intestinal permeability, is increased in association with obesity-associated insulin resistance","volume":"7","author":"Moreno-Navarrete","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.clnu.2024.12.017_bib27","article-title":"Gut microbiota, microinflammation, metabolic profile, and zonulin concentration in obese and normal weight subjects","volume":"2013","author":"Zak-Go\u0142\u0105b","year":"2013","journal-title":"Internet J Endocrinol"},{"key":"10.1016\/j.clnu.2024.12.017_bib28","first-page":"1","article-title":"Brazil and cashew nuts intake improve body composition and endothelial health in women at cardiometabolic risk (Brazilian Nuts Study): a randomized controlled trial","author":"Caldas","year":"2022","journal-title":"Br J Nutr"},{"key":"10.1016\/j.clnu.2024.12.017_bib29","article-title":"Cashew nut (Anacardium occidentale L.) and cashew nut oil reduce cardiovascular risk factors in adults on weight-loss treatment: a randomized controlled three-arm trial (Brazilian Nuts Study)","volume":"11","author":"Meneguelli","year":"2024","journal-title":"Front Nutr [Internet]"},{"key":"10.1016\/j.clnu.2024.12.017_bib30","unstructured":"STROBE [Internet]. [citado 25 de julho de 2024]. Strobe. Dispon\u00edvel em: https:\/\/www.strobe-statement.org\/."},{"issue":"3","key":"10.1016\/j.clnu.2024.12.017_bib31","doi-asserted-by":"crossref","first-page":"317","DOI":"10.12820\/rbafs.v.18n3p317","article-title":"Valida\u00e7\u00e3o de dois question\u00e1rios para a avalia\u00e7\u00e3o da atividade f\u00edsica em adultos","volume":"18","author":"Garcia","year":"2013","journal-title":"Revista Brasileira de Atividade F\u00edsica & Sa\u00fade"},{"issue":"7","key":"10.1016\/j.clnu.2024.12.017_bib32","doi-asserted-by":"crossref","first-page":"3347","DOI":"10.1210\/jc.2010-0288","article-title":"The product of triglycerides and glucose, a simple measure of insulin sensitivity. Comparison with the euglycemic-hyperinsulinemic clamp","volume":"95","author":"Guerrero-Romero","year":"2010","journal-title":"J Clin Endocrinol Metab"},{"issue":"7","key":"10.1016\/j.clnu.2024.12.017_bib33","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1007\/BF00280883","article-title":"Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man","volume":"28","author":"Matthews","year":"1985","journal-title":"Diabetologia"},{"issue":"3","key":"10.1016\/j.clnu.2024.12.017_bib34","doi-asserted-by":"crossref","first-page":"398","DOI":"10.2174\/092986711794839179","article-title":"Intestinal epithelial barrier dysfunction in disease and possible therapeutical interventions","volume":"18","author":"Catalioto","year":"2011","journal-title":"Curr Med Chem"},{"issue":"5","key":"10.1016\/j.clnu.2024.12.017_bib35","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1053\/gast.2002.36578","article-title":"Host-dependent zonulin secretion causes the impairment of the small intestine barrier function after bacterial exposure","volume":"123","author":"Asmar","year":"2002","journal-title":"Gastroenterology"},{"issue":"1","key":"10.1016\/j.clnu.2024.12.017_bib36","doi-asserted-by":"crossref","first-page":"G11","DOI":"10.1152\/ajpgi.00113.2021","article-title":"Biomarkers for assessment of intestinal permeability in clinical practice","volume":"321","author":"Seethaler","year":"2021","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"issue":"5","key":"10.1016\/j.clnu.2024.12.017_bib37","doi-asserted-by":"crossref","first-page":"G589","DOI":"10.1152\/ajpgi.00245.2020","article-title":"Effects of dietary components on intestinal permeability in health and disease","volume":"319","author":"Khoshbin","year":"2020","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"issue":"11","key":"10.1016\/j.clnu.2024.12.017_bib38","doi-asserted-by":"crossref","first-page":"3164","DOI":"10.3390\/cells10113164","article-title":"High-fat, western-style diet, systemic inflammation, and gut microbiota: a narrative Review","volume":"10","author":"Malesza","year":"2021","journal-title":"Cells"},{"key":"10.1016\/j.clnu.2024.12.017_bib39","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.673708","article-title":"Partners in leaky gut syndrome: intestinal dysbiosis and autoimmunity","volume":"12","author":"Kinashi","year":"2021","journal-title":"Front Immunol"},{"issue":"6","key":"10.1016\/j.clnu.2024.12.017_bib40","doi-asserted-by":"crossref","first-page":"1769","DOI":"10.3390\/nu12061769","article-title":"Thyroid-Gut-Axis: how does the microbiota influence thyroid function?","volume":"12","author":"Knezevic","year":"2020","journal-title":"Nutrients"},{"issue":"20","key":"10.1016\/j.clnu.2024.12.017_bib41","article-title":"Polysorbate 80-induced leaky gut impairs skeletal muscle metabolism in mice","volume":"8","author":"Nishimura","year":"2020","journal-title":"Phys Rep"},{"key":"10.1016\/j.clnu.2024.12.017_bib42","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1186\/s12876-014-0189-7","article-title":"Intestinal permeability \u2013 a new target for disease prevention and therapy","volume":"14","author":"Bischoff","year":"2014","journal-title":"BMC Gastroenterol"},{"issue":"4","key":"10.1016\/j.clnu.2024.12.017_bib43","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.3390\/nu12041082","article-title":"Gut microbiome, intestinal permeability, and tissue bacteria in metabolic disease: perpetrators or bystanders?","volume":"12","author":"Chakaroun","year":"2020","journal-title":"Nutrients"},{"issue":"1","key":"10.1016\/j.clnu.2024.12.017_bib44","doi-asserted-by":"crossref","first-page":"31","DOI":"10.4274\/jcrpe.3682","article-title":"The relationship between serum zonulin level and clinical and laboratory parameters of childhood obesity","volume":"9","author":"K\u00fcme","year":"2017","journal-title":"J Clin Res Pediatr Endocrinol"},{"issue":"10","key":"10.1016\/j.clnu.2024.12.017_bib45","doi-asserted-by":"crossref","DOI":"10.1111\/ijpo.12946","article-title":"Serum zonulin as an index of glucose dysregulation in children and adolescents with overweight and obesity","volume":"17","author":"Olivieri","year":"2022","journal-title":"Pediatr Obes"},{"issue":"1","key":"10.1016\/j.clnu.2024.12.017_bib46","doi-asserted-by":"crossref","first-page":"127","DOI":"10.3945\/ajcn.116.131110","article-title":"Gut permeability is related to body weight, fatty liver disease, and insulin resistance in obese individuals undergoing weight reduction","volume":"105","author":"Damms-Machado","year":"2017","journal-title":"Am J Clin Nutr"},{"issue":"4","key":"10.1016\/j.clnu.2024.12.017_bib47","first-page":"571","article-title":"Impact of diet and synbiotics on selected gut bacteria and intestinal permeability in individuals with excess body weight - a Prospective, Randomized Study","volume":"67","author":"Janczy","year":"2020","journal-title":"Acta Biochim Pol"},{"issue":"8","key":"10.1016\/j.clnu.2024.12.017_bib48","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1080\/10408398.2014.995264","article-title":"A role for whey-derived lactoferrin and immunoglobulins in the attenuation of obesity-related inflammation and disease","volume":"57","author":"Brimelow","year":"2017","journal-title":"Crit Rev Food Sci Nutr"},{"issue":"4","key":"10.1016\/j.clnu.2024.12.017_bib49","first-page":"308","article-title":"The human gut microbiota: metabolism and perspective in obesity","volume":"9","author":"Gomes","year":"2018","journal-title":"Gut Microb"},{"issue":"7","key":"10.1016\/j.clnu.2024.12.017_bib50","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.3390\/cells11071239","article-title":"The influence of gut dysbiosis in the pathogenesis and management of ischemic stroke","volume":"11","author":"Chidambaram","year":"2022","journal-title":"Cells"},{"issue":"1","key":"10.1016\/j.clnu.2024.12.017_bib51","doi-asserted-by":"crossref","first-page":"28","DOI":"10.3390\/nu13010028","article-title":"Niacin and butyrate: nutraceuticals targeting dysbiosis and intestinal permeability in Parkinson's disease","volume":"13","author":"Karunaratne","year":"2020","journal-title":"Nutrients"},{"issue":"5","key":"10.1016\/j.clnu.2024.12.017_bib52","doi-asserted-by":"crossref","first-page":"731","DOI":"10.5713\/ajas.15.0415","article-title":"The effects of glucagon-like peptide-2 on the tight junction and barrier function in IPEC-J2 cells through phosphatidylinositol 3-kinase\u2013Protein kinase B\u2013mammalian target of rapamycin signaling pathway","volume":"29","author":"Yu","year":"2016","journal-title":"Asian-Australas J Anim Sci"},{"issue":"7","key":"10.1016\/j.clnu.2024.12.017_bib53","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1002\/1873-3468.14328","article-title":"Lipopolysaccharide and the gut microbiota: considering structural variation","volume":"596","author":"Mohr","year":"2022","journal-title":"FEBS Lett"},{"issue":"24","key":"10.1016\/j.clnu.2024.12.017_bib54","doi-asserted-by":"crossref","first-page":"4038","DOI":"10.3390\/cells11244038","article-title":"Role of endogenous lipopolysaccharides in neurological disorders","volume":"11","author":"Kalyan","year":"2022","journal-title":"Cells"},{"key":"10.1016\/j.clnu.2024.12.017_bib55","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.atherosclerosis.2015.11.015","article-title":"Saturated fatty acids trigger TLR4-mediated inflammatory response","volume":"244","author":"Rocha","year":"2016","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.clnu.2024.12.017_bib56","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/5514075","article-title":"Sinapic acid alleviated inflammation-induced intestinal epithelial barrier dysfunction in lipopolysaccharide- (LPS-) treated caco-2 cells","volume":"2021","author":"Lan","year":"2021","journal-title":"Mediat Inflamm"},{"issue":"7","key":"10.1016\/j.clnu.2024.12.017_bib57a","doi-asserted-by":"crossref","first-page":"1466","DOI":"10.1007\/s11605-023-05654-4","article-title":"Gut barrier dysfunction and bacterial lipopolysaccharides in colorectal cancer","volume":"27","author":"Li","year":"2023","journal-title":"J Gastrointest Surg"},{"issue":"7","key":"10.1016\/j.clnu.2024.12.017_bib57b","doi-asserted-by":"crossref","first-page":"1466","DOI":"10.1007\/s11605-023-05654-4","article-title":"Gut barrier dysfunction and bacterial lipopolysaccharides in colorectal cancer","volume":"27","author":"Li","year":"2023","journal-title":"J Gastrointest Surg"},{"issue":"3","key":"10.1016\/j.clnu.2024.12.017_bib58","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1016\/j.tjnut.2023.12.022","article-title":"Daily cashew and Brazil nut consumption modifies intestinal health in overweight women on energy-restricted intervention: a randomized controlled trial (Brazilian nuts study)","volume":"154","author":"Kelly Souza Silveira","year":"2024","journal-title":"J Nutr"},{"issue":"6","key":"10.1016\/j.clnu.2024.12.017_bib59","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1042\/CS20200895","article-title":"The complex role of adipokines in obesity, inflammation, and autoimmunity","volume":"135","author":"Taylor","year":"2021","journal-title":"Clin Sci Lond Engl"},{"issue":"5","key":"10.1016\/j.clnu.2024.12.017_bib60","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1016\/j.jhep.2023.01.024","article-title":"An adipocentric perspective on the development and progression of non-alcoholic fatty liver disease","volume":"78","author":"Lee","year":"2023","journal-title":"J Hepatol"},{"key":"10.1016\/j.clnu.2024.12.017_bib61","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.biochi.2023.04.008","article-title":"Adipokines in obesity and metabolic-related-diseases","volume":"212","author":"Pestel","year":"2023","journal-title":"Biochimie"},{"issue":"39","key":"10.1016\/j.clnu.2024.12.017_bib62","doi-asserted-by":"crossref","first-page":"16799","DOI":"10.1073\/pnas.0906773106","article-title":"Identification of human zonulin, a physiological modulator of tight junctions, as prehaptoglobin-2","volume":"106","author":"Tripathi","year":"2009","journal-title":"Proc Natl Acad Sci USA"},{"issue":"46","key":"10.1016\/j.clnu.2024.12.017_bib63","doi-asserted-by":"crossref","first-page":"40142","DOI":"10.1074\/jbc.M111.251793","article-title":"MicroRNA-18a enhances the interleukin-6-mediated production of the acute-phase proteins fibrinogen and haptoglobin in human hepatocytes","volume":"286","author":"Brock","year":"2011","journal-title":"J Biol Chem"},{"issue":"2","key":"10.1016\/j.clnu.2024.12.017_bib64","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/j.diabres.2014.08.017","article-title":"Circulating zonulin levels in newly diagnosed Chinese type 2 diabetes patients","volume":"106","author":"Zhang","year":"2014","journal-title":"Diabetes Res Clin Pract"},{"issue":"3","key":"10.1016\/j.clnu.2024.12.017_bib65","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1128\/CMR.16.3.379-414.2003","article-title":"Receptors, mediators, and mechanisms involved in bacterial sepsis and septic shock","volume":"16","author":"Amersfoort","year":"2003","journal-title":"Clinical Microbiology Reviews. julho de"},{"issue":"3","key":"10.1016\/j.clnu.2024.12.017_bib66","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1093\/cvr\/cvu150","article-title":"HDL in innate and adaptive immunity","volume":"103","author":"Catapano","year":"2014","journal-title":"Cardiovasc Res"},{"issue":"11","key":"10.1016\/j.clnu.2024.12.017_bib67","doi-asserted-by":"crossref","first-page":"2280","DOI":"10.1038\/oby.2011.251","article-title":"Intestinal permeability is associated with visceral adiposity in healthy women","volume":"19","author":"Gummesson","year":"2011","journal-title":"Obesity (Silver Spring)"},{"issue":"3","key":"10.1016\/j.clnu.2024.12.017_bib68","doi-asserted-by":"crossref","DOI":"10.1016\/j.beem.2021.101507","article-title":"Gut microbiome, prebiotics, intestinal permeability and diabetes complications","volume":"35","author":"Snelson","year":"2021","journal-title":"Best Pract Res Clin Endocrinol Metabol"},{"key":"10.1016\/j.clnu.2024.12.017_bib69","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/B978-0-12-800100-4.00003-9","article-title":"The role of short-chain fatty acids in health and disease","volume":"121","author":"Tan","year":"2014","journal-title":"Adv Immunol"},{"key":"10.1016\/j.clnu.2024.12.017_bib70","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.ebiom.2018.03.030","article-title":"Sodium butyrate inhibits inflammation and maintains epithelium barrier integrity in a TNBS-induced inflammatory bowel disease mice model","volume":"30","author":"Chen","year":"2018","journal-title":"EBioMedicine"},{"issue":"1","key":"10.1016\/j.clnu.2024.12.017_bib71","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.immuni.2013.12.007","article-title":"Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis","volume":"40","author":"Singh","year":"2014","journal-title":"Immunity"},{"issue":"5","key":"10.1016\/j.clnu.2024.12.017_bib72","doi-asserted-by":"crossref","first-page":"545","DOI":"10.5603\/EP.a2021.0056","article-title":"Serum zonulin levels in type 2 diabetes patients with diabetic kidney disease","volume":"72","author":"Sirin","year":"2021","journal-title":"Endokrynol Pol"},{"issue":"2","key":"10.1016\/j.clnu.2024.12.017_bib73","doi-asserted-by":"crossref","DOI":"10.1136\/rmdopen-2023-003895","article-title":"Work-related physical strain and development of joint inflammation in the trajectory of emerging inflammatory and rheumatoid arthritis: a prospective cohort study","volume":"10","author":"van Dijk","year":"2024","journal-title":"RMD Open"}],"container-title":["Clinical Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0261561424004588?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0261561424004588?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,14]],"date-time":"2025-02-14T15:21:20Z","timestamp":1739546480000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0261561424004588"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":74,"alternative-id":["S0261561424004588"],"URL":"https:\/\/doi.org\/10.1016\/j.clnu.2024.12.017","relation":{},"ISSN":["0261-5614"],"issn-type":[{"value":"0261-5614","type":"print"}],"subject":[],"published":{"date-parts":[[2025,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Adiposity and inflammation markers explain mostly part of the plasma zonulin variation in Brazilian adults with overweight\/obesity: A cross-sectional analysis from Brazilian nuts study","name":"articletitle","label":"Article Title"},{"value":"Clinical Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clnu.2024.12.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}