{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T17:14:58Z","timestamp":1786986898137,"version":"build-2736575974"},"reference-count":18,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","clinicalnutritionjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Nutrition"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1016\/j.clnu.2025.06.017","type":"journal-article","created":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T19:09:36Z","timestamp":1750878576000},"page":"206-211","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["The association between serum zonulin levels and sarcopenia in older adults: How does intestinal permeability affect sarcopenia?"],"prefix":"10.1016","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9193-5327","authenticated-orcid":false,"given":"K\u00fcbra","family":"Erdo\u011fan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bet\u00fcl G\u00fcls\u00fcm","family":"Yavuz Veizi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selim","family":"Demirci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Semih","family":"Sezer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00d6zg\u00fcr","family":"Kara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.clnu.2025.06.017_bib1","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1093\/ageing\/afy169","article-title":"Sarcopenia: revised European consensus on definition and diagnosis","volume":"48","author":"Cruz-Jentoft","year":"2019","journal-title":"Age Ageing"},{"key":"10.1016\/j.clnu.2025.06.017_bib2","doi-asserted-by":"crossref","DOI":"10.3346\/jkms.2022.37.e146","article-title":"A review of sarcopenia pathophysiology, diagnosis, treatment and future direction","volume":"37","author":"Cho","year":"2022","journal-title":"J Kor Med Sci"},{"key":"10.1016\/j.clnu.2025.06.017_bib3","first-page":"86","article-title":"Dietary protein recommendations and the prevention of sarcopenia","volume":"12","author":"Paddon-Jones","year":"2009","journal-title":"Curr Opin Clin Nutr Metab Care"},{"key":"10.1016\/j.clnu.2025.06.017_bib4","doi-asserted-by":"crossref","first-page":"963","DOI":"10.3389\/fphys.2020.00963","article-title":"Myosteatosis in the context of skeletal muscle function deficit: an interdisciplinary workshop at the National Institute on Aging","volume":"11","author":"Correa-de-Araujo","year":"2020","journal-title":"Front Physiol"},{"key":"10.1016\/j.clnu.2025.06.017_bib5","doi-asserted-by":"crossref","DOI":"10.1080\/21688370.2016.1251384","article-title":"Zonulin, a regulator of epithelial and endothelial barrier functions, and its involvement in chronic inflammatory diseases","volume":"4","author":"Sturgeon","year":"2016","journal-title":"Tissue Barriers"},{"key":"10.1016\/j.clnu.2025.06.017_bib6","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1093\/ageing\/afq034","article-title":"Sarcopenia: european consensus on definition and diagnosis: report of the European Working Group on Sarcopenia in older people","volume":"39","author":"Cruz-Jentoft","year":"2010","journal-title":"Age Ageing"},{"key":"10.1016\/j.clnu.2025.06.017_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.rmed.2021.106662","article-title":"Intestinal permeability marker zonulin as a predictor of sarcopenia in chronic obstructive pulmonary disease","volume":"189","author":"Karim","year":"2021","journal-title":"Respir Med"},{"key":"10.1016\/j.clnu.2025.06.017_bib8","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.neures.2022.08.004","article-title":"Elevated plasma zonulin and CAF22 are correlated with sarcopenia and functional dependency at various stages of Alzheimer's diseases","volume":"184","author":"Karim","year":"2022","journal-title":"Neurosci Res"},{"key":"10.1016\/j.clnu.2025.06.017_bib9","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1097\/PHM.0000000000001439","article-title":"STAR-sonographic thigh adjustment ratio: a golden formula for the diagnosis of sarcopenia","volume":"99","author":"Kara","year":"2020","journal-title":"Am J Phys Med Rehabil"},{"key":"10.1016\/j.clnu.2025.06.017_bib10","doi-asserted-by":"crossref","DOI":"10.2340\/16501977-2851","article-title":"Diagnosing sarcopenia: functional perspectives and a new algorithm from the ISarcoPRM","volume":"53","author":"Kara","year":"2021","journal-title":"J Rehabil Med"},{"key":"10.1016\/j.clnu.2025.06.017_bib11","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.673708","article-title":"Partners in leaky gut syndrome: intestinal dysbiosis and autoimmunity","volume":"12","author":"Kinashi","year":"2021","journal-title":"Front Immunol"},{"key":"10.1016\/j.clnu.2025.06.017_bib12","doi-asserted-by":"crossref","first-page":"1989","DOI":"10.36740\/WLek\/195166","article-title":"Specifics of barrier function impairment of the large intestine in patients with ulcerative collitis and joint damage","volume":"77","author":"Varvarynets","year":"2024","journal-title":"Wiad Lek"},{"key":"10.1016\/j.clnu.2025.06.017_bib13","doi-asserted-by":"crossref","first-page":"1602","DOI":"10.1017\/S0007114524002824","article-title":"Probiotics' supplementation alleviates disease severity and improves postural balance by repairing intestinal leak in patients suffering from osteoarthritis: a double-blinded clinical trial","volume":"132","author":"Karim","year":"2024","journal-title":"Br J Nutr"},{"key":"10.1016\/j.clnu.2025.06.017_bib14","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1007\/s00223-024-01233-0","article-title":"The association of intestinal leak with sarcopenia and physical disability in patients with various stages of chronic kidney disease","volume":"115","author":"Qaisar","year":"2024","journal-title":"Calcif Tissue Int"},{"key":"10.1016\/j.clnu.2025.06.017_bib15","doi-asserted-by":"crossref","DOI":"10.3390\/nu16091369","article-title":"A patented dietary supplement (Hydroxy-Methyl-Butyrate, carnosine, magnesium, butyrate, lactoferrin) is a promising therapeutic target for age-related sarcopenia through the regulation of gut permeability: a randomized controlled trial","volume":"16","author":"Rondanelli","year":"2024","journal-title":"Nutrients"},{"key":"10.1016\/j.clnu.2025.06.017_bib16","doi-asserted-by":"crossref","DOI":"10.3390\/foods13223635","article-title":"The impact of green tea Kombucha on the intestinal health, gut microbiota, and serum metabolome of individuals with excess body weight in a weight loss intervention: a randomized controlled trial","volume":"13","author":"Fraiz","year":"2024","journal-title":"Foods"},{"key":"10.1016\/j.clnu.2025.06.017_bib17","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1007\/s11136-023-03547-2","article-title":"A leaky gut contributes to reduced sarcopenia-related quality of life (SarQoL) in geriatric older adults","volume":"33","author":"Qaisar","year":"2024","journal-title":"Qual Life Res"},{"key":"10.1016\/j.clnu.2025.06.017_bib18","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1007\/s10238-024-01496-9","article-title":"Intestinal permeability disturbances: causes, diseases and therapy","volume":"24","author":"Macura","year":"2024","journal-title":"Clin Exp Med"}],"container-title":["Clinical Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0261561425001712?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0261561425001712?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,7,24]],"date-time":"2025-07-24T22:29:20Z","timestamp":1753396160000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0261561425001712"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":18,"alternative-id":["S0261561425001712"],"URL":"https:\/\/doi.org\/10.1016\/j.clnu.2025.06.017","relation":{},"ISSN":["0261-5614"],"issn-type":[{"value":"0261-5614","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The association between serum zonulin levels and sarcopenia in older adults: How does intestinal permeability affect sarcopenia?","name":"articletitle","label":"Article Title"},{"value":"Clinical Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clnu.2025.06.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}