{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T00:33:33Z","timestamp":1793234013616,"version":"4.5.0"},"reference-count":61,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T00:00:00Z","timestamp":1788134400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100014911","name":"Ministry of Defence and Armed Forces of the Czech Republic","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100014911","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007397","name":"Charles University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007397","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","clinicalnutritionjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Nutrition"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.clnu.2026.106777","type":"journal-article","created":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T15:54:05Z","timestamp":1788364445000},"page":"106777","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Whole-body Omega-3 and Omega-6 fatty-acid reserves in healthy controls and fatal COVID-19: Evidence of systemic long-chain n\u20133 depletion"],"prefix":"10.1016","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9401-1848","authenticated-orcid":false,"given":"Pavel","family":"Sko\u0159epa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7391-8619","authenticated-orcid":false,"given":"Zden\u011bk","family":"Zad\u00e1k","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3269-1817","authenticated-orcid":false,"given":"Marek","family":"Vecka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4182-4407","authenticated-orcid":false,"given":"Michal","family":"Burda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dalibor","family":"Kova\u0159\u00edk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9308-624X","authenticated-orcid":false,"given":"Petr","family":"Hejna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6815-0780","authenticated-orcid":false,"given":"Iva Selke","family":"Krulichov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Radom\u00edr","family":"Hy\u0161pler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1329-1268","authenticated-orcid":false,"given":"Alena","family":"Tich\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3561-9482","authenticated-orcid":false,"given":"Miroslav","family":"Fajfr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2691-6458","authenticated-orcid":false,"given":"Pavel","family":"Bo\u0161t\u00edk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ale\u0161","family":"\u017d\u00e1k","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.clnu.2026.106777_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.plipres.2022.101165","article-title":"Polyunsaturated fatty acids and fatty acid-derived lipid mediators: recent advances in the understanding of their biosynthesis, structures, and functions","volume":"86","author":"Dyall","year":"2022","journal-title":"Prog Lipid Res"},{"key":"10.1016\/j.clnu.2026.106777_bib2","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1007\/s13668-021-00363-3","article-title":"Dietary polyunsaturated fatty acids (PUFAs): uses and potential health benefits","volume":"10","author":"Kapoor","year":"2021","journal-title":"Current nutrition reports"},{"key":"10.1016\/j.clnu.2026.106777_bib3","doi-asserted-by":"crossref","DOI":"10.3390\/ijms24108838","article-title":"Polyunsaturated fatty acids: conversion to lipid mediators, roles in inflammatory diseases and dietary sources","volume":"24","author":"Harwood","year":"2023","journal-title":"Int J Mol Sci"},{"issue":"Suppl 1","key":"10.1016\/j.clnu.2026.106777_bib4","doi-asserted-by":"crossref","first-page":"S50","DOI":"10.1016\/j.ejphar.2011.05.085","article-title":"Fatty acids and inflammation: the cutting edge between food and pharma","volume":"668","author":"Calder","year":"2011","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.clnu.2026.106777_bib5","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/j.bbalip.2014.08.010","article-title":"Marine omega-3 fatty acids and inflammatory processes: effects, mechanisms and clinical relevance","volume":"1851","author":"Calder","year":"2015","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.clnu.2026.106777_bib6","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.jnutbio.2011.07.001","article-title":"Biophysical and biochemical mechanisms by which dietary N-3 polyunsaturated fatty acids from fish oil disrupt membrane lipid rafts","volume":"23","author":"Shaikh","year":"2012","journal-title":"J Nutr Biochem"},{"key":"10.1016\/j.clnu.2026.106777_bib7","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1038\/nrn3820","article-title":"Polyunsaturated fatty acids and their metabolites in brain function and disease","volume":"15","author":"Bazinet","year":"2014","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.clnu.2026.106777_bib8","doi-asserted-by":"crossref","first-page":"674","DOI":"10.3181\/0711-MR-311","article-title":"The importance of the omega-6\/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases","volume":"233","author":"Simopoulos","year":"2008","journal-title":"Exp Biol Med"},{"key":"10.1016\/j.clnu.2026.106777_bib9","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1038\/nature13479","article-title":"Pro-resolving lipid mediators are leads for resolution physiology","volume":"510","author":"Serhan","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.clnu.2026.106777_bib10","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1136\/bmjnph-2020-000085","article-title":"Nutrition, immunity and COVID-19","volume":"3","author":"Calder","year":"2020","journal-title":"BMJ Nutr Prev Health"},{"key":"10.1016\/j.clnu.2026.106777_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.plefa.2021.102250","article-title":"Blood omega-3 fatty acids and death from COVID-19: a pilot study","volume":"166","author":"Asher","year":"2021","journal-title":"Prostaglandins Leukot Essent Fatty Acids"},{"key":"10.1016\/j.clnu.2026.106777_bib12","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1186\/s12967-021-02795-5","article-title":"The effect of omega-3 fatty acid supplementation on clinical and biochemical parameters of critically ill patients with COVID-19: a randomized clinical trial","volume":"19","author":"Doaei","year":"2021","journal-title":"J Transl Med"},{"key":"10.1016\/j.clnu.2026.106777_bib13","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1139\/H07-034","article-title":"Extremely limited synthesis of long chain polyunsaturates in adults: implications for their dietary essentiality and use as supplements","volume":"32","author":"Plourde","year":"2007","journal-title":"Appl Physiol Nutr Metab"},{"key":"10.1016\/j.clnu.2026.106777_bib14","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.plipres.2015.04.002","article-title":"Is docosahexaenoic acid synthesis from \u03b1-linolenic acid sufficient to supply the adult brain?","volume":"59","author":"Domenichiello","year":"2015","journal-title":"Prog Lipid Res"},{"key":"10.1016\/j.clnu.2026.106777_bib15","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/j.plipres.2008.03.003","article-title":"Fatty acid composition of adipose tissue and blood in humans and its use as a biomarker of dietary intake","volume":"47","author":"Hodson","year":"2008","journal-title":"Prog Lipid Res"},{"key":"10.1016\/j.clnu.2026.106777_bib16","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.ypmed.2004.02.030","article-title":"The Omega-3 index: a new risk factor for death from coronary heart disease?","volume":"39","author":"Harris","year":"2004","journal-title":"Prev Med"},{"key":"10.1016\/j.clnu.2026.106777_bib17","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.atherosclerosis.2017.05.007","article-title":"The Omega-3 index and relative risk for coronary heart disease mortality: estimation from 10 cohort studies","volume":"262","author":"Harris","year":"2017","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.clnu.2026.106777_bib18","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1136\/hrt.70.6.524","article-title":"Linoleic acid and risk of sudden cardiac death","volume":"70","author":"Roberts","year":"1993","journal-title":"Br Heart J"},{"key":"10.1016\/j.clnu.2026.106777_bib19","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0140-6736(87)90001-8","article-title":"Linoleic and eicosapentaenoic acids in adipose tissue and platelets and risk of coronary heart disease","volume":"1","author":"Wood","year":"1987","journal-title":"Lancet"},{"key":"10.1016\/j.clnu.2026.106777_bib20","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1161\/01.ATV.19.4.1111","article-title":"Omega-3 fatty acids in adipose tissue and risk of myocardial infarction: the EURAMIC study","volume":"19","author":"Guallar","year":"1999","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.clnu.2026.106777_bib21","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1093\/ajcn\/77.4.796","article-title":"Adipose tissue n-6 fatty acids and acute myocardial infarction in a population consuming a diet high in polyunsaturated fatty acids","volume":"77","author":"Kark","year":"2003","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.clnu.2026.106777_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.jnutbio.2019.108231","article-title":"Enrichment of brain docosahexaenoic acid (DHA) is highly dependent upon the molecular carrier of dietary DHA: Lysophosphatidylcholine is more efficient than either phosphatidylcholine or triacylglycerol","volume":"74","author":"Sugasini","year":"2019","journal-title":"J Nutr Biochem"},{"key":"10.1016\/j.clnu.2026.106777_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.pharmthera.2023.108440","article-title":"The essential role of docosahexaenoic acid and its derivatives for retinal integrity","volume":"247","author":"Swinkels","year":"2023","journal-title":"Pharmacol Ther"},{"key":"10.1016\/j.clnu.2026.106777_bib24","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.1093\/ajcn\/76.6.1222","article-title":"Fatty acid composition of skeletal muscle reflects dietary fat composition in humans","volume":"76","author":"Andersson","year":"2002","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.clnu.2026.106777_bib25","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1042\/CS20030326","article-title":"Increase in long-chain polyunsaturated fatty acid n - 6\/n - 3 ratio in relation to hepatic steatosis in patients with non-alcoholic fatty liver disease","volume":"106","author":"Araya","year":"2004","journal-title":"Clin Sci (Lond)"},{"key":"10.1016\/j.clnu.2026.106777_bib26","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1194\/jlr.P040501","article-title":"Altered renal lipid metabolism and renal lipid accumulation in human diabetic nephropathy","volume":"55","author":"Herman-Edelstein","year":"2014","journal-title":"J Lipid Res"},{"key":"10.1016\/j.clnu.2026.106777_bib27","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.atherosclerosis.2007.03.018","article-title":"Tissue n-3 and n-6 fatty acids and risk for coronary heart disease events","volume":"193","author":"Harris","year":"2007","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.clnu.2026.106777_bib28","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/0021-9150(93)90021-L","article-title":"Fatty acid composition in total phospholipids of human coronary arteries in sudden cardiac death","volume":"99","author":"Luostarinen","year":"1993","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.clnu.2026.106777_bib29","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1007\/BF02544583","article-title":"Phospholipid content and fatty acid composition of human heart","volume":"24","author":"Rocquelin","year":"1989","journal-title":"Lipids"},{"key":"10.1016\/j.clnu.2026.106777_bib30","series-title":"Guidelines for ethical research on human remains","year":"2022"},{"key":"10.1016\/j.clnu.2026.106777_bib31","doi-asserted-by":"crossref","first-page":"2191","DOI":"10.1001\/jama.2013.281053","article-title":"World Medical Association declaration of helsinki: ethical principles for Medical research involving human subjects","volume":"310","author":"Association","year":"2013","journal-title":"JAMA"},{"key":"10.1016\/j.clnu.2026.106777_bib32","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S0021-9258(18)64849-5","article-title":"A simple method for the isolation and purification of total lipides from animal tissues","volume":"226","author":"Folch","year":"1957","journal-title":"J Biol Chem"},{"key":"10.1016\/j.clnu.2026.106777_bib33","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/0009-8981(85)90277-3","article-title":"Extraction of lipids from human whole serum and lipoproteins and from rat liver tissue with methylene chloride-methanol: a comparison with extraction with chloroform-methanol","volume":"149","author":"Carlson","year":"1985","journal-title":"Clin Chim Acta"},{"key":"10.1016\/j.clnu.2026.106777_bib34","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S1570-0232(01)00630-4","article-title":"Effect of column and software on gas chromatographic determination of fatty acids","volume":"770","author":"Vecka","year":"2002","journal-title":"J Chromatogr, B: Anal Technol Biomed Life Sci"},{"key":"10.1016\/j.clnu.2026.106777_bib35","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1079\/BJN19910073","article-title":"Body mass index as a measure of body fatness: age- and sex-specific prediction formulas","volume":"65","author":"Deurenberg","year":"1991","journal-title":"Br J Nutr"},{"key":"10.1016\/j.clnu.2026.106777_bib36","doi-asserted-by":"crossref","first-page":"2012","DOI":"10.1016\/S0022-2275(20)37132-7","article-title":"Kinetics of the incorporation of dietary fatty acids into serum cholesteryl esters, erythrocyte membranes, and adipose tissue: an 18-month controlled study","volume":"38","author":"Katan","year":"1997","journal-title":"J Lipid Res"},{"key":"10.1016\/j.clnu.2026.106777_bib37","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.1016\/S0022-2275(20)32206-9","article-title":"Sources of eicosanoid precursor fatty acid pools in tissues","volume":"42","author":"Zhou","year":"2001","journal-title":"J Lipid Res"},{"key":"10.1016\/j.clnu.2026.106777_bib38","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1146\/annurev-nutr-082018-124250","article-title":"FADS1 and FADS2 polymorphisms modulate Fatty acid metabolism and dietary impact on health","volume":"39","author":"Koletzko","year":"2019","journal-title":"Annu Rev Nutr"},{"key":"10.1016\/j.clnu.2026.106777_bib39","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.ymgme.2011.02.012","article-title":"Polymorphisms in FADS1 and FADS2 alter desaturase activity in young Caucasian and Asian adults","volume":"103","author":"Merino","year":"2011","journal-title":"Mol Genet Metabol"},{"key":"10.1016\/j.clnu.2026.106777_bib40","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2021.667024","article-title":"Alteration in the lipid profile and the desaturases activity in patients with severe pneumonia by SARS-CoV-2","volume":"12","author":"P\u00e9rez-Torres","year":"2021","journal-title":"Front Physiol"},{"key":"10.1016\/j.clnu.2026.106777_bib41","doi-asserted-by":"crossref","first-page":"116","DOI":"10.5507\/bp.2024.014","article-title":"Fat embolism and COVID-19 infection: autopsy and post-mortem laboratory findings in SARS-CoV-2 positive patients","volume":"169","author":"Gavronova","year":"2025","journal-title":"Biomed Pap"},{"key":"10.1016\/j.clnu.2026.106777_bib42","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1186\/s12879-023-08559-4","article-title":"Pulmonary fat embolism: a potentially new fatal complication of SARS-CoV-2 infection. A case report","volume":"23","author":"Kong","year":"2023","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.clnu.2026.106777_bib43","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0163-7827(03)00039-0","article-title":"Regulation of stearoyl-CoA desaturases and role in metabolism","volume":"43","author":"Ntambi","year":"2004","journal-title":"Prog Lipid Res"},{"key":"10.1016\/j.clnu.2026.106777_bib44","doi-asserted-by":"crossref","DOI":"10.1016\/j.jlr.2025.100824","article-title":"Stearoyl-CoA desaturase 1 deficiency drives saturated lipid accumulation and increases liver and plasma acylcarnitines","volume":"66","author":"Kalyesubula","year":"2025","journal-title":"J Lipid Res"},{"key":"10.1016\/j.clnu.2026.106777_bib45","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1161\/CIRCRESAHA.116.306842","article-title":"Lipid use and misuse by the heart","volume":"118","author":"Schulze","year":"2016","journal-title":"Circ Res"},{"key":"10.1016\/j.clnu.2026.106777_bib46","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1016\/j.bbalip.2016.02.016","article-title":"Lipid metabolism and signaling in cardiac lipotoxicity","volume":"1861","author":"D'Souza","year":"2016","journal-title":"Biochim Biophys Acta Mol Cell Biol Lipids"},{"key":"10.1016\/j.clnu.2026.106777_bib47","doi-asserted-by":"crossref","first-page":"1905","DOI":"10.1093\/cvr\/cvad100","article-title":"Cardiac lipid metabolism, mitochondrial function, and heart failure","volume":"119","author":"Da Dalt","year":"2023","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.clnu.2026.106777_bib48","doi-asserted-by":"crossref","first-page":"3772","DOI":"10.1002\/ehf2.12958","article-title":"Fatal lymphocytic cardiac damage in coronavirus disease 2019 (COVID-19): Autopsy reveals a ferroptosis signature","volume":"7","author":"Jacobs","year":"2020","journal-title":"ESC Heart Fail"},{"key":"10.1016\/j.clnu.2026.106777_bib49","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/j.chembiol.2018.11.016","article-title":"Exogenous monounsaturated Fatty acids promote a ferroptosis-resistant cell State","volume":"26","author":"Magtanong","year":"2019","journal-title":"Cell Chem Biol"},{"key":"10.1016\/j.clnu.2026.106777_bib50","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2021.675617","article-title":"Fatty acids metabolism: the Bridge between ferroptosis and ionizing radiation","volume":"9","author":"Yuan","year":"2021","journal-title":"Front Cell Dev Biol"},{"key":"10.1016\/j.clnu.2026.106777_bib51","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1001\/jamacardio.2020.3551","article-title":"Association of cardiac infection with SARS-CoV-2 in confirmed COVID-19 Autopsy cases","volume":"5","author":"Lindner","year":"2020","journal-title":"JAMA Cardiol"},{"key":"10.1016\/j.clnu.2026.106777_bib52","doi-asserted-by":"crossref","DOI":"10.1096\/fj.202100540R","article-title":"High levels of eicosanoids and docosanoids in the lungs of intubated COVID-19 patients","volume":"35","author":"Archambault","year":"2021","journal-title":"FASEB J"},{"key":"10.1016\/j.clnu.2026.106777_bib53","doi-asserted-by":"crossref","DOI":"10.1172\/JCI149236","article-title":"Group IIA secreted phospholipase A2 is associated with the pathobiology leading to COVID-19 mortality","volume":"131","author":"Snider","year":"2021","journal-title":"J Clin Investig"},{"key":"10.1016\/j.clnu.2026.106777_bib54","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/j.jaci.2021.05.032","article-title":"Chemokines and eicosanoids fuel the hyperinflammation within the lungs of patients with severe COVID-19","volume":"148","author":"Zaid","year":"2021","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.clnu.2026.106777_bib55","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1186\/1465-9921-8-55","article-title":"Time-dependent changes in pulmonary surfactant function and composition in acute respiratory distress syndrome due to pneumonia or aspiration","volume":"8","author":"Schmidt","year":"2007","journal-title":"Respir Res"},{"key":"10.1016\/j.clnu.2026.106777_bib56","doi-asserted-by":"crossref","first-page":"3007","DOI":"10.1016\/j.clnu.2021.05.031","article-title":"Myosteatosis predicting risk of transition to severe COVID-19 infection","volume":"41","author":"Yi","year":"2022","journal-title":"Clin Nutr"},{"key":"10.1016\/j.clnu.2026.106777_bib57","doi-asserted-by":"crossref","DOI":"10.1016\/j.nut.2023.112327","article-title":"Myosteatosis predicts short-term mortality in patients with COVID-19: a multicenter analysis","volume":"120","author":"Surov","year":"2024","journal-title":"Nutrition"},{"key":"10.1016\/j.clnu.2026.106777_bib58","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2024.105294","article-title":"Renal tubular epithelial cells response to injury in acute kidney injury","volume":"107","author":"Li","year":"2024","journal-title":"EBioMedicine"},{"key":"10.1016\/j.clnu.2026.106777_bib59","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.cell.2020.08.025","article-title":"Loss of Bcl-6-Expressing T follicular helper cells and germinal centers in COVID-19","volume":"183","author":"Kaneko","year":"2020","journal-title":"Cell"},{"key":"10.1016\/j.clnu.2026.106777_bib60","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1038\/nature13241","article-title":"Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid","volume":"509","author":"Nguyen","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.clnu.2026.106777_bib61","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1001\/jamapsychiatry.2021.0500","article-title":"How COVID-19 affects the brain","volume":"78","author":"Boldrini","year":"2021","journal-title":"JAMA Psychiatry"}],"container-title":["Clinical Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0261561426002049?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0261561426002049?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T00:19:25Z","timestamp":1793233165000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0261561426002049"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":61,"alternative-id":["S0261561426002049"],"URL":"https:\/\/doi.org\/10.1016\/j.clnu.2026.106777","relation":{},"ISSN":["0261-5614"],"issn-type":[{"value":"0261-5614","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Whole-body Omega-3 and Omega-6 fatty-acid reserves in healthy controls and fatal COVID-19: Evidence of systemic long-chain n\u20133 depletion","name":"articletitle","label":"Article Title"},{"value":"Clinical Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clnu.2026.106777","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"106777"}}