{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T17:45:23Z","timestamp":1761155123170,"version":"build-2065373602"},"reference-count":37,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2008,4,1]],"date-time":"2008-04-01T00:00:00Z","timestamp":1207008000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,4,1]],"date-time":"2008-04-01T00:00:00Z","timestamp":1207008000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","clinicaloncologyonline.net","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Oncology"],"published-print":{"date-parts":[[2008,4]]},"DOI":"10.1016\/j.clon.2007.12.011","type":"journal-article","created":{"date-parts":[[2008,2,8]],"date-time":"2008-02-08T10:02:20Z","timestamp":1202464940000},"page":"253-260","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["An Evaluation of Conformal and Intensity-modulated Radiotherapy in Whole Ventricular Radiotherapy for Localised Primary Intracranial Germinomas"],"prefix":"10.1016","volume":"20","author":[{"given":"E.","family":"Raggi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.A.","family":"Mosleh-Shirazi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.H.","family":"Saran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.clon.2007.12.011_bib1","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1023\/A:1012721723387","article-title":"Pathology of pineal region tumors","volume":"54","author":"Hirato","year":"2001","journal-title":"J\u00a0Neurooncol"},{"key":"10.1016\/j.clon.2007.12.011_bib2","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/S0167-8140(98)00017-6","article-title":"Pathologically-proven intracranial germinoma treated with radiation therapy","volume":"47","author":"Aoyama","year":"1998","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.clon.2007.12.011_bib3","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/S0360-3016(97)00330-1","article-title":"Intracranial germinoma: the case for lower dose radiation therapy","volume":"39","author":"Hardenbergh","year":"1997","journal-title":"Int J\u00a0Radiat Oncol Biol Phys"},{"key":"10.1016\/j.clon.2007.12.011_bib4","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/0167-8140(95)01649-X","article-title":"Radiotherapy of intracranial germinomas","volume":"38","author":"Huh","year":"1996","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.clon.2007.12.011_bib5","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1016\/j.ijrobp.2003.08.028","article-title":"Craniospinal radiation in the treatment of biopsy-proven intracranial germinomas: twenty-five years' experience in a single centre","volume":"58","author":"Maity","year":"2004","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.clon.2007.12.011_bib6","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/S0360-3016(96)00607-4","article-title":"Analysis of long-term treatment of intracranial germinoma","volume":"37","author":"Shirato","year":"1997","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.clon.2007.12.011_bib7","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1148\/128.3.745","article-title":"Midline pineal tumors and suprasellar germinomas: highly curable by irradiation","volume":"128","author":"Sung","year":"1978","journal-title":"Radiology"},{"key":"10.1016\/j.clon.2007.12.011_bib8","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/S1470-2045(05)70245-X","article-title":"Radiotherapy of localised intracranial germinoma: time to sever historical ties?","volume":"6","author":"Rogers","year":"2005","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.clon.2007.12.011_bib9","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/0736-5748(94)90081-7","article-title":"Cognitive deficits in long-term survivors of childhood medulloblastoma and other noncortical tumors: age-dependent effects of whole brain radiation","volume":"12","author":"Radcliff","year":"1994","journal-title":"Int J Dev Neurosci"},{"key":"10.1016\/j.clon.2007.12.011_bib10","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1200\/JCO.2004.05.186","article-title":"Change in neurocognitive functioning after treatment with cranial radiation in childhood","volume":"22","author":"Spiegler","year":"2004","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.clon.2007.12.011_bib11","doi-asserted-by":"crossref","first-page":"2302","DOI":"10.1200\/JCO.2001.19.8.2302","article-title":"Patterns of intellectual development among survivors of pediatric medulloblastoma: a longitudinal analysis","volume":"19","author":"Palmer","year":"2001","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.clon.2007.12.011_bib12","doi-asserted-by":"crossref","first-page":"329","DOI":"10.3109\/08880019009033410","article-title":"Influence of age, sex, and concurrent intrathecal methotrexate therapy on intellectual function after cranial irradiation during childhood: a report from the Children's Cancer Study Group","volume":"7","author":"Bleyer","year":"1990","journal-title":"Pediatr Hematol Oncol"},{"key":"10.1016\/j.clon.2007.12.011_bib13","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/S0140-6736(94)92997-1","article-title":"Association of 1800 cGy cranial irradiation with intellectual function in children with acute lymphoblastic leukaemia. ISPACC. International Study Group on Psychosocial Aspects of Childhood Cancer","volume":"344","author":"Jankovic","year":"1994","journal-title":"Lancet"},{"key":"10.1016\/j.clon.2007.12.011_bib14","doi-asserted-by":"crossref","first-page":"2127","DOI":"10.1200\/JCO.1999.17.7.2127","article-title":"Treatment of children with medulloblastomas with reduced-dose craniospinal radiation therapy and adjuvant chemotherapy: a Children's Cancer Group Study","volume":"17","author":"Packer","year":"1999","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.clon.2007.12.011_bib15","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1016\/S0360-3016(03)01569-4","article-title":"Assessment of different IMRT boost delivery methods on target coverage and normal-tissue sparing","volume":"57","author":"Dogan","year":"2003","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.clon.2007.12.011_bib16","first-page":"53","article-title":"How precise is manual CT-MRI registration for cranial radiotherapy planning?","volume":"3","author":"Mosleh-Shirazi","year":"2005","journal-title":"Iran J Radiat Res"},{"key":"10.1016\/j.clon.2007.12.011_bib17","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1016\/0360-3016(93)90548-A","article-title":"Radiation therapy oncology group: radiosurgery quality assurance guidelines","volume":"27","author":"Shaw","year":"1993","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.clon.2007.12.011_bib18","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/S0360-3016(99)00156-X","article-title":"Optimization of stereotactically-guided conformal treatment planning of sellar and parasellar tumors, based on normal brain dose volume histograms","volume":"45","author":"Perks","year":"1999","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"Suppl 1","key":"10.1016\/j.clon.2007.12.011_bib19","first-page":"S83","article-title":"Can we gain from complexity? Optimization of stereotactically-guided conformal radiotherapy of brain tumors based on normal brain dose volume histograms","volume":"64","author":"Ajithkumar","year":"2002","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.clon.2007.12.011_bib20","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1038\/sj.bjc.6690192","article-title":"Combined treatment modality for intracranial germinomas: results of a multicentre SFOP experience. Societe Francaise d'Oncologie Pediatrique","volume":"79","author":"Bouffet","year":"1999","journal-title":"Br J Cancer"},{"key":"10.1016\/j.clon.2007.12.011_bib21","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/S0360-3016(02)04611-4","article-title":"Radiation therapy for intracranial germ cell tumors","volume":"56","author":"Haas-Kogan","year":"2003","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.clon.2007.12.011_bib22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ijrobp.2006.01.027","article-title":"Intensity-modulated radiation therapy, protons, and the risk of second cancers","volume":"65","author":"Hall","year":"2006","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.clon.2007.12.011_bib23","doi-asserted-by":"crossref","first-page":"3226","DOI":"10.1200\/JCO.1999.17.10.3226","article-title":"Acute myelogenous leukemia after treatment for malignant germ cell tumours in children","volume":"17","author":"Schneider","year":"1999","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.clon.2007.12.011_bib24","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1037\/0894-4105.17.4.548","article-title":"Predicting intellectual outcome among children treated with 35\u201340 Gy craniospinal irradiation for medulloblastoma","volume":"17","author":"Palmer","year":"2003","journal-title":"Neuropsychology"},{"key":"10.1016\/j.clon.2007.12.011_bib25","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1016\/S0360-3016(99)00375-2","article-title":"CNS germinoma: disease control and long-term functional outcome for 12 children treated with craniospinal irradiation","volume":"46","author":"Merchant","year":"2000","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.clon.2007.12.011_bib26","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1093\/neuonc\/3.3.174","article-title":"Long-term quality of life and neuropsychologic functioning for patients with CNS germ-cell tumors: from the First International CNS Germ-Cell Tumor Study","volume":"3","author":"Sands","year":"2001","journal-title":"Neuro-Oncology"},{"key":"10.1016\/j.clon.2007.12.011_bib27","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1097\/00006123-199912000-00002","article-title":"Quality of life of adult survivors of germinomas treated with craniospinal irradiation","volume":"45","author":"Sutton","year":"1999","journal-title":"Neurosurgery"},{"key":"10.1016\/j.clon.2007.12.011_bib28","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1016\/S0140-6736(02)11398-5","article-title":"Effect of radiotherapy and other treatment-related factors on mid-term to long-term cognitive sequelae in low-grade gliomas: a comparative study","volume":"360","author":"Klein","year":"2002","journal-title":"Lancet"},{"key":"10.1016\/j.clon.2007.12.011_bib29","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1002\/pbc.20257","article-title":"Intracranial germinoma: on whole-ventricular irradiation","volume":"44","author":"Roberge","year":"2005","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.clon.2007.12.011_bib30","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1111\/j.1651-2227.1986.tb10195.x","article-title":"The effect of cranial irradiation on growth hormone secretion","volume":"75","author":"Ahmet","year":"1986","journal-title":"Acta Paediatr Scand"},{"key":"10.1016\/j.clon.2007.12.011_bib31","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1200\/JCO.1999.17.3.933","article-title":"Phase II trial of primary chemotherapy followed by reduced-dose radiation for CNS germ cell tumors","volume":"17","author":"Buchner","year":"1999","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.clon.2007.12.011_bib32","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0140-6736(97)01116-1","article-title":"Radiation and genetic factors in the risk of second malignant neoplasms after a first cancer in childhood","volume":"350","author":"Kony","year":"1997","journal-title":"Lancet"},{"key":"10.1016\/j.clon.2007.12.011_bib33","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1080\/08880010390243031","article-title":"Second malignant neoplasms after primary central nervous system malignancies of childhood and adolescence","volume":"20","author":"Devarahally","year":"2003","journal-title":"Pediatr Hematol Oncol"},{"key":"10.1016\/j.clon.2007.12.011_bib34","doi-asserted-by":"crossref","first-page":"3163","DOI":"10.1200\/JCO.2001.19.13.3163","article-title":"Late mortality experience in five-year survivors of childhood and adolescent cancer: the Childhood Cancer Survivor Study","volume":"19","author":"Mertens","year":"2001","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.clon.2007.12.011_bib35","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/s00066-002-0826-x","article-title":"Radiation therapy in the multimodal treatment approach of pituitary adenoma","volume":"178","author":"Becker","year":"2002","journal-title":"Strahlenther Onkol"},{"key":"10.1016\/j.clon.2007.12.011_bib36","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/S0360-3016(99)00159-5","article-title":"The incidence of cerebrovascular accidents in patients with pituitary adenoma","volume":"45","author":"Brada","year":"1999","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.clon.2007.12.011_bib37","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1667\/RR3329","article-title":"Long-term follow-up for brain tumor development after childhood exposure to ionising radiation for tinea capitis","volume":"163","author":"Sadetzki","year":"2005","journal-title":"Radiat Res"}],"container-title":["Clinical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0936655508000034?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0936655508000034?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T15:32:39Z","timestamp":1760542359000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0936655508000034"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,4]]},"references-count":37,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2008,4]]}},"alternative-id":["S0936655508000034"],"URL":"https:\/\/doi.org\/10.1016\/j.clon.2007.12.011","relation":{},"ISSN":["0936-6555"],"issn-type":[{"type":"print","value":"0936-6555"}],"subject":[],"published":{"date-parts":[[2008,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"An Evaluation of Conformal and Intensity-modulated Radiotherapy in Whole Ventricular Radiotherapy for Localised Primary Intracranial Germinomas","name":"articletitle","label":"Article Title"},{"value":"Clinical Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clon.2007.12.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2008 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}