{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T00:52:51Z","timestamp":1760575971535,"version":"build-2065373602"},"reference-count":5,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2008,9,1]],"date-time":"2008-09-01T00:00:00Z","timestamp":1220227200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,9,1]],"date-time":"2008-09-01T00:00:00Z","timestamp":1220227200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","clinicaloncologyonline.net","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Oncology"],"published-print":{"date-parts":[[2008,9]]},"DOI":"10.1016\/j.clon.2008.05.004","type":"journal-article","created":{"date-parts":[[2008,6,17]],"date-time":"2008-06-17T05:11:51Z","timestamp":1213679511000},"page":"566-567","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Oesophageal Variceal Bleeding in Hepatocellular Carcinoma with Portal Vein Thrombosis: Improved Outcome in Response to Molecular Target Therapy"],"prefix":"10.1016","volume":"20","author":[{"given":"S.S.","family":"Wu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.H.","family":"Yen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.Y.","family":"Chung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.clon.2008.05.004_bib1","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1016\/j.jhep.2005.01.021","article-title":"MELD score and hepatocellular carcinoma identify patients at different risk of short-term mortality among cirrhotics bleeding from esophageal varices","volume":"42","author":"Amitrano","year":"2005","journal-title":"J Hepatol"},{"key":"10.1016\/j.clon.2008.05.004_bib2","first-page":"379","article-title":"FDA approves sorafenib for patients with inoperable liver cancer","volume":"134","author":"Lang","year":"2008","journal-title":"Gastroenterology"},{"key":"10.1016\/j.clon.2008.05.004_bib3","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1111\/j.1440-1746.2006.04418.x","article-title":"What are the risk factors for aggravation of esophageal varices in patients with hepatocellular carcinoma?","volume":"22","author":"Kadouchi","year":"2007","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1016\/j.clon.2008.05.004_bib4","doi-asserted-by":"crossref","first-page":"11851","DOI":"10.1158\/0008-5472.CAN-06-1377","article-title":"Sorafenib blocks the RAF\/MEK\/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC\/PRF\/5","volume":"66","author":"Liu","year":"2006","journal-title":"Cancer Res"},{"key":"10.1016\/j.clon.2008.05.004_bib5","doi-asserted-by":"crossref","first-page":"4293","DOI":"10.1200\/JCO.2005.01.3441","article-title":"Phase II study of sorafenib in patients with advanced hepatocellular carcinoma","volume":"24","author":"Abou-Alfa","year":"2006","journal-title":"J\u00a0Clin Oncol"}],"container-title":["Clinical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0936655508002550?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0936655508002550?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T15:33:25Z","timestamp":1760542405000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0936655508002550"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,9]]},"references-count":5,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2008,9]]}},"alternative-id":["S0936655508002550"],"URL":"https:\/\/doi.org\/10.1016\/j.clon.2008.05.004","relation":{},"ISSN":["0936-6555"],"issn-type":[{"type":"print","value":"0936-6555"}],"subject":[],"published":{"date-parts":[[2008,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Oesophageal Variceal Bleeding in Hepatocellular Carcinoma with Portal Vein Thrombosis: Improved Outcome in Response to Molecular Target Therapy","name":"articletitle","label":"Article Title"},{"value":"Clinical Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clon.2008.05.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2008 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}