{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T03:23:01Z","timestamp":1789874581964,"version":"4.0.1"},"reference-count":37,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2010,4,1]],"date-time":"2010-04-01T00:00:00Z","timestamp":1270080000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,4,1]],"date-time":"2010-04-01T00:00:00Z","timestamp":1270080000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","clinicaloncologyonline.net","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Oncology"],"published-print":{"date-parts":[[2010,4]]},"DOI":"10.1016\/j.clon.2009.12.002","type":"journal-article","created":{"date-parts":[[2010,1,6]],"date-time":"2010-01-06T05:54:43Z","timestamp":1262757283000},"page":"199-207","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":24,"title":["Frequency of Opioid Use in a Population of Cancer Patients During the Trajectory of the Disease"],"prefix":"10.1016","volume":"22","author":[{"given":"L.","family":"Jarlbaek","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.G.","family":"Hansen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Bruera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Andersen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.clon.2009.12.002_bib1","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1097\/00002508-199312000-00009","article-title":"Pain as an early symptom in cancer","volume":"9","author":"Vuorinen","year":"1993","journal-title":"Clin J Pain"},{"issue":"9","key":"10.1016\/j.clon.2009.12.002_bib2","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1093\/annonc\/mdm056","article-title":"Prevalence of pain in patients with cancer: a systematic review of the past 40 years","volume":"18","author":"van den Beuken-van Everdingen","year":"2007","journal-title":"Ann Oncol"},{"issue":"2","key":"10.1016\/j.clon.2009.12.002_bib3","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1177\/104990910402100213","article-title":"Epidemiology of cancer pain and factors influencing poor pain control","volume":"21","author":"Davis","year":"2004","journal-title":"Am J Hosp Palliat Care"},{"issue":"12","key":"10.1016\/j.clon.2009.12.002_bib4","doi-asserted-by":"crossref","first-page":"1985","DOI":"10.1093\/annonc\/mdn419","article-title":"Prevalence of undertreatment in cancer pain. A review of published literature","volume":"19","author":"Deandrea","year":"2008","journal-title":"Ann Oncol"},{"key":"10.1016\/j.clon.2009.12.002_bib5","author":"World Health Organization"},{"key":"10.1016\/j.clon.2009.12.002_bib6","series-title":"Management of cancer pain. summary, evidence report\/technology assessment: Number 35. AHRQ Publication No. 01-E033","author":"Agency for Healthcare Research and Quality","year":"2001"},{"issue":"Suppl. 2","key":"10.1016\/j.clon.2009.12.002_bib7","doi-asserted-by":"crossref","first-page":"ii119","DOI":"10.1093\/annonc\/mdn108","article-title":"Management of cancer pain: ESMO clinical recommendations","volume":"19","author":"Jost","year":"2008","journal-title":"Ann Oncol"},{"issue":"6","key":"10.1016\/j.clon.2009.12.002_bib8","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1016\/j.ejpain.2007.10.012","article-title":"What do different databases tell about the use of opioids in seven European countries in 2002?","volume":"12","author":"Hamunen","year":"2008","journal-title":"Eur J Pain"},{"key":"10.1016\/j.clon.2009.12.002_bib9","series-title":"Cancer pain relief. With a guide to opioid availability","author":"World Health Organization","year":"1996"},{"issue":"1","key":"10.1016\/j.clon.2009.12.002_bib10","first-page":"28","article-title":"Italy reforms national policy for cancer pain relief and opioids","volume":"12","author":"Blengini","year":"2003","journal-title":"Eur J Cancer Care (Engl)"},{"issue":"2","key":"10.1016\/j.clon.2009.12.002_bib11","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1093\/ije\/25.2.435","article-title":"A framework for evaluation of secondary data sources for epidemiological research","volume":"25","author":"Sorensen","year":"1996","journal-title":"Int J Epidemiol"},{"key":"10.1016\/j.clon.2009.12.002_bib12","author":"Danish National Board of Health"},{"issue":"5","key":"10.1016\/j.clon.2009.12.002_bib13","first-page":"535","article-title":"The Danish Cancer Registry\u2014history, content, quality and use","volume":"44","author":"Storm","year":"1997","journal-title":"Dan Med Bull"},{"issue":"4","key":"10.1016\/j.clon.2009.12.002_bib14","first-page":"445","article-title":"The Danish prescription registries","volume":"44","author":"Gaist","year":"1997","journal-title":"Dan Med Bull"},{"issue":"1","key":"10.1016\/j.clon.2009.12.002_bib15","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.jpainsymman.2003.05.002","article-title":"Cancer patients' share in a population's use of opioids. A linkage study between a prescription database and the Danish Cancer Registry","volume":"27","author":"Jarlbaek","year":"2004","journal-title":"J Pain Symptom Manage"},{"issue":"4","key":"10.1016\/j.clon.2009.12.002_bib16","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/j.jpainsymman.2004.07.010","article-title":"Use of opioids in a Danish population-based cohort of cancer patients","volume":"29","author":"Jarlbaek","year":"2005","journal-title":"J Pain Symptom Manage"},{"issue":"7","key":"10.1016\/j.clon.2009.12.002_bib17","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1002\/pds.638","article-title":"Conducting pharmacoepidemiologic research in Denmark","volume":"10","author":"Hallas","year":"2001","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"10.1016\/j.clon.2009.12.002_bib18","series-title":"Guidelines for ATC classification and DDD assignment 2002","author":"World Health Organization","year":"2002"},{"issue":"2","key":"10.1016\/j.clon.2009.12.002_bib19","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/S0885-3924(00)00160-3","article-title":"The course of symptom frequency and intensity in advanced cancer patients followed at home","volume":"20","author":"Mercadante","year":"2000","journal-title":"J Pain Symptom Manage"},{"issue":"5","key":"10.1016\/j.clon.2009.12.002_bib20","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/S0885-3924(98)00091-8","article-title":"Symptoms and functional status of patients with disseminated cancer visiting outpatient departments","volume":"16","author":"Schuit","year":"1998","journal-title":"J Pain Symptom Manage"},{"issue":"3","key":"10.1016\/j.clon.2009.12.002_bib21","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/j.pain.2007.08.022","article-title":"High prevalence of pain in patients with cancer in a large population-based study in The Netherlands","volume":"132","author":"van den Beuken-van Everdingen","year":"2007","journal-title":"Pain"},{"issue":"5","key":"10.1016\/j.clon.2009.12.002_bib22","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/S1470-2045(03)01079-9","article-title":"The use of opioids and sedatives at the end of life","volume":"4","author":"Sykes","year":"2003","journal-title":"Lancet Oncol"},{"issue":"6986","key":"10.1016\/j.clon.2009.12.002_bib23","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1136\/bmj.310.6986.1034","article-title":"Multicentre study of cancer pain and its treatment in France","volume":"310","author":"Larue","year":"1995","journal-title":"Br Med J"},{"issue":"9","key":"10.1016\/j.clon.2009.12.002_bib24","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1007\/s00277-007-0296-4","article-title":"Epidemiology, features and outcome of pain in patients with advanced hematological malignancies followed in a home care program: an Italian survey","volume":"86","author":"Niscola","year":"2007","journal-title":"Ann Hematol"},{"issue":"5","key":"10.1016\/j.clon.2009.12.002_bib25","doi-asserted-by":"crossref","first-page":"238","DOI":"10.12968\/ijpn.2008.14.5.29491","article-title":"Pain in elderly hospitalized cancer patients with bone metastases in Norway","volume":"14","author":"Torvik","year":"2008","journal-title":"Int J Palliat Nurs"},{"issue":"9","key":"10.1016\/j.clon.2009.12.002_bib26","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1093\/gerona\/63.9.960","article-title":"Patient age, well-being, perspectives, and care practices in the early treatment phase for late-stage cancer","volume":"63","author":"Rose","year":"2008","journal-title":"J\u00a0Gerontol A Biol Sci Med Sci"},{"issue":"4","key":"10.1016\/j.clon.2009.12.002_bib27","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1111\/j.1533-2500.2008.00204.x","volume":"8","author":"Pergolizzi","year":"2008","journal-title":"Pain Pract"},{"issue":"1","key":"10.1016\/j.clon.2009.12.002_bib28","first-page":"56","article-title":"Management of pain in the older person with cancer","volume":"22","author":"Delgado-Guay","year":"2008","journal-title":"Oncology (Williston Park)"},{"issue":"3","key":"10.1016\/j.clon.2009.12.002_bib29","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/0304-3959(95)00154-9","article-title":"Management of cancer pain in Denmark: a nationwide questionnaire survey","volume":"64","author":"Sjogren","year":"1996","journal-title":"Pain"},{"key":"10.1016\/j.clon.2009.12.002_bib30","first-page":"1529","article-title":"The use of opioids in Denmark [Opioidforbruget i Danmark]","volume":"73","author":"Froelund","year":"1995","journal-title":"Maanedsskr Prakt Laegegern"},{"issue":"7\u20138","key":"10.1016\/j.clon.2009.12.002_bib31","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1080\/028418698430142","article-title":"Use of morphine and other opioids in the Nordic countries","volume":"37","author":"Vainio","year":"1998","journal-title":"Acta Oncol"},{"key":"10.1016\/j.clon.2009.12.002_bib32","author":"INCB"},{"key":"10.1016\/j.clon.2009.12.002_bib33","author":"Danish Medicines Agency [L\u00e6gemiddelstyrelsen]"},{"issue":"4","key":"10.1016\/j.clon.2009.12.002_bib34","first-page":"340","article-title":"Cancer patients' first treatment episode with opioids: a pharmaco-epidemiological perspective","volume":"14","author":"Jarlbaek","year":"2006","journal-title":"Support Care Cancer"},{"issue":"4","key":"10.1016\/j.clon.2009.12.002_bib35","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.jclinepi.2004.10.012","article-title":"A review of uses of health care utilization databases for epidemiologic research on therapeutics","volume":"58","author":"Schneeweiss","year":"2005","journal-title":"J\u00a0Clin Epidemiol"},{"issue":"1\u20132","key":"10.1016\/j.clon.2009.12.002_bib36","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.pain.2004.09.002","article-title":"Pain relief: a universal human right","volume":"112","author":"Cousins","year":"2004","journal-title":"Pain"},{"issue":"1","key":"10.1016\/j.clon.2009.12.002_bib37","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1089\/109662104322737377","article-title":"Improving availability of opioid pain medications: testing the principle of balance in latin America","volume":"7","author":"Joranson","year":"2004","journal-title":"J Palliat Med"}],"container-title":["Clinical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0936655509004087?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0936655509004087?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T15:35:23Z","timestamp":1760542523000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0936655509004087"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,4]]},"references-count":37,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2010,4]]}},"alternative-id":["S0936655509004087"],"URL":"https:\/\/doi.org\/10.1016\/j.clon.2009.12.002","relation":{},"ISSN":["0936-6555"],"issn-type":[{"value":"0936-6555","type":"print"}],"subject":[],"published":{"date-parts":[[2010,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Frequency of Opioid Use in a Population of Cancer Patients During the Trajectory of the Disease","name":"articletitle","label":"Article Title"},{"value":"Clinical Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clon.2009.12.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}