{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T11:25:35Z","timestamp":1778585135785,"version":"3.51.4"},"reference-count":25,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T00:00:00Z","timestamp":1480550400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T00:00:00Z","timestamp":1480550400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","clinicaloncologyonline.net","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Oncology"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1016\/j.clon.2016.06.013","type":"journal-article","created":{"date-parts":[[2016,7,4]],"date-time":"2016-07-04T09:15:14Z","timestamp":1467623714000},"page":"e173-e178","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":32,"title":["High-quality Linac-based Stereotactic Body Radiation Therapy with Flattening Filter Free Beams and Volumetric Modulated Arc Therapy for Low\u2013Intermediate Risk Prostate Cancer. A Mono-institutional Experience with 90 Patients"],"prefix":"10.1016","volume":"28","author":[{"given":"G.","family":"D'Agostino","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Franzese","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"De Rose","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Franceschini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Comito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Villa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Alongi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Liardo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Tomatis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Navarria","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Mancosu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Reggiori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7862-898X","authenticated-orcid":false,"given":"L.","family":"Cozzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Scorsetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.clon.2016.06.013_bib1","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1001\/jamaoncol.2015.0735","article-title":"The global burden of cancer 2013","volume":"1","author":"Global Burden of Disease Cancer Collaboration","year":"2015","journal-title":"JAMA Oncol"},{"key":"10.1016\/j.clon.2016.06.013_bib2","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.eururo.2013.09.046","article-title":"EAU Guidelines on Prostate Cancer. Part 1: screening, diagnosis, and local treatment with curative intent \u2013 update 2013","volume":"65","author":"Heidenreich","year":"2014","journal-title":"Eur Urol"},{"key":"10.1016\/j.clon.2016.06.013_bib3","series-title":"Prostate cancer, Version I","author":"NCCN Clinical Practice Guidelines in Oncology","year":"2015"},{"key":"10.1016\/j.clon.2016.06.013_bib4","doi-asserted-by":"crossref","first-page":"1940","DOI":"10.1200\/JCO.2010.34.2006","article-title":"Future of treatment for low-risk prostate cancer: for all, for some, or for none?","volume":"29","author":"D'Amico","year":"2011","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.clon.2016.06.013_bib5","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1056\/NEJMoa1113162","article-title":"Radical prostatectomy versus observation for localized prostate cancer","volume":"367","author":"Wilt","year":"2012","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.clon.2016.06.013_bib6","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/j.eururo.2014.08.009","article-title":"A\u00a0systematic review of hypofractionation for primary management of prostate cancer","volume":"68","author":"Koontz","year":"2015","journal-title":"Eur Urol"},{"key":"10.1016\/j.clon.2016.06.013_bib7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/PPO.0b013e3181976614","article-title":"Hypofractionation for prostate cancer","volume":"15","author":"Ritter","year":"2009","journal-title":"Cancer J"},{"key":"10.1016\/j.clon.2016.06.013_bib8","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.critrevonc.2011.11.009","article-title":"Will SBRT replace conventional radiotherapy in patients with low-intermediate risk prostate cancer? A review","volume":"84","author":"Arcangeli","year":"2012","journal-title":"Crit Rev Oncol Hematol"},{"key":"10.1016\/j.clon.2016.06.013_bib9","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1186\/1748-717X-8-171","article-title":"Linac based SBRT for prostate cancer in 5 fractions with VMAT and flattening filter free beams: preliminary report of a phase II study","volume":"8","author":"Alongi","year":"2013","journal-title":"Radiat Oncol"},{"key":"10.1016\/j.clon.2016.06.013_bib10","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1001\/jama.280.11.969","article-title":"Biochemical outcome after radical prostatectomy, external beam radiation therapy, or interstitial radiation therapy for clinically localized prostate cancer","volume":"280","author":"D\u2019Amico","year":"1998","journal-title":"JAMA"},{"key":"10.1016\/j.clon.2016.06.013_bib11","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1016\/j.ijrobp.2008.07.021","article-title":"Calcifications are potential surrogates for prostate localization in image-guided radiotherapy","volume":"72","author":"Zeng","year":"2008","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.clon.2016.06.013_bib12","doi-asserted-by":"crossref","first-page":"1795","DOI":"10.1007\/s00432-014-1732-1","article-title":"Stereotactic body radiotherapy with flattening filter-free beams for prostate cancer: assessment of patient-reported quality of life","volume":"140","author":"Scorsetti","year":"2014","journal-title":"J\u00a0Cancer Res Clin Oncol"},{"key":"10.1016\/j.clon.2016.06.013_bib13","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1016\/S0090-4295(00)00858-X","article-title":"Development and validation of the expanded prostate cancer index composite (EPIC) for comprehensive assessment of health related quality of life in men with prostate cancer","volume":"56","author":"Wei","year":"2000","journal-title":"Urology"},{"key":"10.1016\/j.clon.2016.06.013_bib14","unstructured":"Common Terminology Criteria for Adverse Events (CTCAE). Version 4.0. (v4.03: June 14, 2010). Available at: http:\/\/evs.nci.nih.gov\/ftp1\/CTCAE\/CTCAE_4.03_2010-06-14_QuickReference_8.5x11.pdf."},{"key":"10.1016\/j.clon.2016.06.013_bib15","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.clon.2015.01.011","article-title":"Stereotactic body radiotherapy for prostate cancer","volume":"27","author":"Henderson","year":"2015","journal-title":"Clin Oncol"},{"key":"10.1016\/j.clon.2016.06.013_bib16","first-page":"876","article-title":"High dose radiation delivered by intensity modulated conformal radiotherapy improves the outcome of localized prostate cancer","volume":"166","author":"Zelefsky","year":"2001","journal-title":"J\u00a0Urol"},{"key":"10.1016\/j.clon.2016.06.013_bib17","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.ijrobp.2008.03.015","article-title":"Does image-guided radiotherapy improve toxicity profile in whole pelvic-treated high-risk prostate cancer? Comparison between IG-IMRT and IMRT","volume":"73","author":"Chung","year":"2009","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.clon.2016.06.013_bib18","first-page":"583","article-title":"Treating prostate cancer with radiotherapy","volume":"7","author":"Wilkins","year":"2010","journal-title":"Nature Rev"},{"key":"10.1016\/j.clon.2016.06.013_bib19","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1097\/COC.0b013e3181b4af05","article-title":"Is radical prostatectomy the \u201cgold standard\u201d for localized prostate cancer?","volume":"33","author":"Mendenhall","year":"2010","journal-title":"Am J Clin Oncol"},{"key":"10.1016\/j.clon.2016.06.013_bib20","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1200\/JCO.2014.59.8128","article-title":"Brachytherapy: where has it gone?","volume":"33","author":"Petereit","year":"2015","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.clon.2016.06.013_bib21","first-page":"3371","article-title":"Cone beam CT pre- and post-daily treatment for assessing geometrical and dosimetric intrafraction variability during radiotherapy of prostate cancer","volume":"12","author":"Reggiori","year":"2010","journal-title":"J\u00a0Appl Clin Med Phys"},{"key":"10.1016\/j.clon.2016.06.013_bib22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fonc.2015.00048","article-title":"Dose-escalated robotic SBRT for stage I-II prostate cancer","volume":"5","author":"Meier","year":"2015","journal-title":"Front Oncol"},{"key":"10.1016\/j.clon.2016.06.013_bib23","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/S1053-4296(05)80117-1","article-title":"Randomized trials in loco-regionally confined prostate cancer: past, present, and future","volume":"3","author":"Zietman","year":"1993","journal-title":"Semin Radiat Oncol"},{"key":"10.1016\/j.clon.2016.06.013_bib24","series-title":"Phase III study of HYPOfractionated RadioTherapy of intermediate risk localised Prostate Cancer","author":"ISRCTN","year":"2014"},{"key":"10.1016\/j.clon.2016.06.013_bib25","doi-asserted-by":"crossref","first-page":"S365","DOI":"10.1016\/j.ijrobp.2013.06.959","article-title":"Successful patient acceptance of randomization within the PACE study (Prostate Advances in Comparative Evidence)","volume":"87","author":"Tree","year":"2013","journal-title":"Int J Radiat Oncol Biol Phys"}],"container-title":["Clinical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0936655516301728?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0936655516301728?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T15:43:10Z","timestamp":1760542990000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0936655516301728"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12]]},"references-count":25,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["S0936655516301728"],"URL":"https:\/\/doi.org\/10.1016\/j.clon.2016.06.013","relation":{},"ISSN":["0936-6555"],"issn-type":[{"value":"0936-6555","type":"print"}],"subject":[],"published":{"date-parts":[[2016,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"High-quality Linac-based Stereotactic Body Radiation Therapy with Flattening Filter Free Beams and Volumetric Modulated Arc Therapy for Low\u2013Intermediate Risk Prostate Cancer. A Mono-institutional Experience with 90 Patients","name":"articletitle","label":"Article Title"},{"value":"Clinical Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clon.2016.06.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}