{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T00:25:51Z","timestamp":1789431951149,"version":"build-2803163510"},"reference-count":32,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","theclinics.com","clinicalkey.com.au","clinicalkey.fr","perinatology.theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinics in Perinatology"],"published-print":{"date-parts":[[2015,9]]},"DOI":"10.1016\/j.clp.2015.04.007","type":"journal-article","created":{"date-parts":[[2015,5,26]],"date-time":"2015-05-26T22:29:39Z","timestamp":1432679379000},"page":"515-527","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":36,"title":["Hemolytic Disorders Causing Severe Neonatal Hyperbilirubinemia"],"prefix":"10.1016","volume":"42","author":[{"given":"Robert D.","family":"Christensen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hassan M.","family":"Yaish","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.clp.2015.04.007_bib1","series-title":"Neonatal hematology","first-page":"91","article-title":"Neonatal hemolysis","author":"Glader","year":"2014"},{"key":"10.1016\/j.clp.2015.04.007_bib2","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/S0022-3476(67)80410-4","article-title":"Life-span of the fetal red blood cell","volume":"70","author":"Pearson","year":"1967","journal-title":"J\u00a0Pediatr"},{"key":"10.1016\/j.clp.2015.04.007_bib3","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1203\/00006450-199707000-00002","article-title":"The life span of erythrocytes transfused to preterm infants","volume":"42","author":"Bard","year":"1997","journal-title":"Pediatr Res"},{"issue":"10 Pt 2","key":"10.1016\/j.clp.2015.04.007_bib4","doi-asserted-by":"crossref","first-page":"2724","DOI":"10.1111\/trf.12562","article-title":"Mean remaining life span: a new clinically relevant parameter to assess the quality of transfused red blood cells","volume":"54","author":"Kuruvilla","year":"2014","journal-title":"Transfusion"},{"issue":"3","key":"10.1016\/j.clp.2015.04.007_bib5","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.tmrv.2014.03.003","article-title":"Measurement of posttransfusion red cell survival with the biotin label","volume":"28","author":"Mock","year":"2014","journal-title":"Transfus Med Rev"},{"issue":"3","key":"10.1016\/j.clp.2015.04.007_bib6","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1053\/j.semperi.2011.02.005","article-title":"Bilirubin production and the risk of bilirubin neurotoxicity","volume":"35","author":"Stevenson","year":"2011","journal-title":"Semin Perinatol"},{"issue":"3","key":"10.1016\/j.clp.2015.04.007_bib7","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/S1875-9572(10)60027-7","article-title":"Understanding neonatal jaundice: a perspective on causation","volume":"51","author":"Cohen","year":"2010","journal-title":"Pediatr Neonatol"},{"issue":"1","key":"10.1016\/j.clp.2015.04.007_bib8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1172\/JCI106463","article-title":"Endogenous production of carbon monoxide in normal and erythroblastotic newborn infants","volume":"50","author":"Maisels","year":"1971","journal-title":"J\u00a0Clin Invest"},{"issue":"1","key":"10.1016\/j.clp.2015.04.007_bib9","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1542\/peds.2005-3042","article-title":"The contribution of hemolysis to early jaundice in normal newborns","volume":"118","author":"Maisels","year":"2006","journal-title":"Pediatrics"},{"issue":"7","key":"10.1016\/j.clp.2015.04.007_bib10","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1053\/j.semperi.2014.08.006","article-title":"Hyperbilirubinemia, hemolysis, and increased bilirubin neurotoxicity","volume":"38","author":"Kaplan","year":"2014","journal-title":"Semin Perinatol"},{"issue":"3","key":"10.1016\/j.clp.2015.04.007_bib11","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1053\/j.semperi.2011.02.003","article-title":"The clinical syndrome of bilirubin-induced neurologic dysfunction","volume":"35","author":"Johnson","year":"2011","journal-title":"Semin Perinatol"},{"issue":"1\u20132","key":"10.1016\/j.clp.2015.04.007_bib12","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.cccn.2005.01.008","article-title":"Understanding severe hyperbilirubinemia and preventing kernicterus: adjuncts in the interpretation of neonatal serum bilirubin","volume":"356","author":"Kaplan","year":"2005","journal-title":"Clin Chim Acta"},{"issue":"2","key":"10.1016\/j.clp.2015.04.007_bib13","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.bcmd.2012.10.004","article-title":"Unexplained extreme hyperbilirubinemia among neonates in a multihospital healthcare system","volume":"50","author":"Christensen","year":"2013","journal-title":"Blood Cells Mol Dis"},{"issue":"3","key":"10.1016\/j.clp.2015.04.007_bib14","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/j.bcmd.2014.11.018","article-title":"End-tidal carbon monoxide as an indicator of the hemolytic rate","volume":"54","author":"Christensen","year":"2015","journal-title":"Blood Cells Mol Dis"},{"issue":"7","key":"10.1016\/j.clp.2015.04.007_bib15","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1038\/jp.2010.197","article-title":"Haptoglobin concentrations in preterm and term newborns'","volume":"31","author":"Chavez-Bueno","year":"2011","journal-title":"J Perinatol"},{"key":"10.1016\/j.clp.2015.04.007_bib16","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1159\/000320148","article-title":"Neonatal reference ranges for blood concentrations of nucleated red blood cells","volume":"99","author":"Christensen","year":"2010","journal-title":"Neonatology"},{"issue":"Suppl 1","key":"10.1016\/j.clp.2015.04.007_bib17","doi-asserted-by":"crossref","first-page":"S25","DOI":"10.1038\/jp.2008.211","article-title":"Clinical report from the pilot USA Kernicterus Registry (1992 to 2004)","volume":"29","author":"Johnson","year":"2009","journal-title":"J\u00a0Perinatol"},{"issue":"8","key":"10.1016\/j.clp.2015.04.007_bib18","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1038\/jp.2014.68","article-title":"Causes of hemolysis in neonates with extreme hyperbilirubinemia","volume":"34","author":"Christensen","year":"2014","journal-title":"J\u00a0Perinatol"},{"issue":"4","key":"10.1016\/j.clp.2015.04.007_bib19","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1159\/000357378","article-title":"Neonatal hemolytic jaundice: morphologic features of erythrocytes that will help you diagnose the underlying condition","volume":"105","author":"Christensen","year":"2014","journal-title":"Neonatology"},{"key":"10.1016\/j.clp.2015.04.007_bib20","first-page":"27","article-title":"A\u00a0simple method of screening newborn infants for hereditary spherocytosis","volume":"4","author":"Yaish","year":"2013","journal-title":"J\u00a0Appl Hematol"},{"issue":"1","key":"10.1016\/j.clp.2015.04.007_bib21","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1542\/peds.2009-0864","article-title":"Hereditary spherocytosis in neonates with hyperbilirubinemia","volume":"125","author":"Christensen","year":"2010","journal-title":"Pediatrics"},{"issue":"9","key":"10.1016\/j.clp.2015.04.007_bib22","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1038\/jp.2010.212","article-title":"Evaluating neonatal hyperbilirubinemia in late preterm Hispanic twins led to the diagnosis of hereditary spherocytosis in them, and in their sibling and in their mother","volume":"31","author":"Sheffield","year":"2011","journal-title":"J\u00a0Perinatol"},{"issue":"2","key":"10.1016\/j.clp.2015.04.007_bib23","doi-asserted-by":"crossref","first-page":"e531","DOI":"10.1542\/peds.2012-3799","article-title":"Acute kernicterus in a neonate with O\/B blood group incompatibility and a mutation in SLC4A1","volume":"132","author":"Christensen","year":"2013","journal-title":"Pediatrics"},{"issue":"5","key":"10.1016\/j.clp.2015.04.007_bib24","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1038\/jp.2012.67","article-title":"A\u00a0neonate with Coombs-negative hemolytic jaundice with spherocytes but normal erythrocyte indices: a rare case of autosomal-recessive hereditary spherocytosis due to alpha-spectrin deficiency","volume":"33","author":"Yaish","year":"2013","journal-title":"J\u00a0Perinatol"},{"issue":"4","key":"10.1016\/j.clp.2015.04.007_bib25","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1159\/000365586","article-title":"Novel \u03b1-spectrin mutation in trans with \u03b1-spectrin causing severe neonatal jaundice from hereditary spherocytosis","volume":"106","author":"Nussenzveig","year":"2014","journal-title":"Neonatology"},{"issue":"1","key":"10.1016\/j.clp.2015.04.007_bib26","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000354884","article-title":"Variations in both \u03b1-spectrin (SPTA1) and \u03b2-spectrin (SPTB) in a neonate with prolonged jaundice in a family where nine individuals had hereditary elliptocytosis","volume":"105","author":"Christensen","year":"2014","journal-title":"Neonatology"},{"issue":"6","key":"10.1016\/j.clp.2015.04.007_bib27","doi-asserted-by":"crossref","first-page":"e1694","DOI":"10.1542\/peds.2013-1030","article-title":"Neonatal death suspected to be from sepsis was found to be kernicterus with G6PD deficiency","volume":"132","author":"Christensen","year":"2013","journal-title":"Pediatrics"},{"issue":"4","key":"10.1016\/j.clp.2015.04.007_bib28","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/j.jpeds.2011.05.043","article-title":"Six children with pyruvate kinase deficiency from one small town: molecular characterization of the PK-LR gene","volume":"159","author":"Christensen","year":"2011","journal-title":"J\u00a0Pediatr"},{"issue":"8","key":"10.1016\/j.clp.2015.04.007_bib29","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1038\/jp.2014.66","article-title":"End-tidal carbon monoxide and hemolysis","volume":"34","author":"Tidmarsh","year":"2014","journal-title":"J\u00a0Perinatol"},{"key":"10.1016\/j.clp.2015.04.007_bib30","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1542\/peds.2009-0329","article-title":"Hyperbilirubinemia in the newborn infant\u00a0> or\u00a0=35 weeks' gestation: an update with clarifications","volume":"124","author":"Maisels","year":"2009","journal-title":"Pediatrics"},{"key":"10.1016\/j.clp.2015.04.007_bib31","article-title":"Evaluating eosin-5-maleimide binding as a diagnostic test for hereditary spherocytosis in newborn infants","author":"Christensen","year":"2014","journal-title":"J\u00a0Perinatol"},{"issue":"2","key":"10.1016\/j.clp.2015.04.007_bib32","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1159\/000363219","article-title":"A\u00a0previously unknown mutation in the pyruvate kinase gene (PKLR) identified from a neonate with severe jaundice","volume":"106","author":"Yaish","year":"2014","journal-title":"Neonatology"}],"container-title":["Clinics in Perinatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0095510815000378?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0095510815000378?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,22]],"date-time":"2018-09-22T09:54:34Z","timestamp":1537610074000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0095510815000378"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9]]},"references-count":32,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015,9]]}},"alternative-id":["S0095510815000378"],"URL":"https:\/\/doi.org\/10.1016\/j.clp.2015.04.007","relation":{},"ISSN":["0095-5108"],"issn-type":[{"value":"0095-5108","type":"print"}],"subject":[],"published":{"date-parts":[[2015,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hemolytic Disorders Causing Severe Neonatal Hyperbilirubinemia","name":"articletitle","label":"Article Title"},{"value":"Clinics in Perinatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clp.2015.04.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}