{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T15:07:30Z","timestamp":1789139250833,"version":"build-2803163510"},"reference-count":87,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinics in Perinatology"],"published-print":{"date-parts":[[2020,9]]},"DOI":"10.1016\/j.clp.2020.05.006","type":"journal-article","created":{"date-parts":[[2020,5,15]],"date-time":"2020-05-15T16:46:19Z","timestamp":1589561179000},"page":"593-615","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"title":["Updates on Management for Acute and Chronic Phenotypes of Neonatal Pulmonary Hypertension"],"prefix":"10.1016","volume":"47","author":[{"given":"Jessica Lauren","family":"Ruoss","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle R.","family":"Rios","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip T.","family":"Levy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.clp.2020.05.006_bib1","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/j.siny.2015.03.001","article-title":"Persistent pulmonary hypertension of the newborn: advances in diagnosis and treatment","volume":"20","author":"Jain","year":"2015","journal-title":"Semin Fetal Neonatal Med"},{"issue":"2","key":"10.1016\/j.clp.2020.05.006_bib2","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1007\/s11936-019-0713-8","article-title":"Comprehensive evaluation of right heart performance and pulmonary hemodynamics in neonatal pulmonary hypertension","volume":"21","author":"Bhattacharya","year":"2019","journal-title":"Curr Treat Options Cardiovasc Med"},{"key":"10.1016\/j.clp.2020.05.006_bib3","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1038\/pr.2017.200","article-title":"Controversies in the identification and management of acute pulmonary hypertension in preterm neonates","volume":"82","author":"Giesinger","year":"2017","journal-title":"Pediatr Res"},{"key":"10.1016\/j.clp.2020.05.006_bib4","doi-asserted-by":"crossref","first-page":"e20161165","DOI":"10.1542\/peds.2016-1165","article-title":"Persistent pulmonary hypertension of the newborn in late preterm and term infants in California","volume":"13","author":"Steurer","year":"2017","journal-title":"Pediatrics"},{"key":"10.1016\/j.clp.2020.05.006_bib5","first-page":"157","article-title":"Diagnosis and management of persistent pulmonary hypertension of the newborn","volume":"16","author":"Bendapudi","year":"2015","journal-title":"Paediatr Respir Rev"},{"key":"10.1016\/j.clp.2020.05.006_bib6","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1542\/peds.113.3.559","article-title":"A\u00a0randomized trial of early versus standard inhaled nitric oxide therapy in term and near-term newborn infants with hypoxic respiratory failure","volume":"113","author":"Konduri","year":"2004","journal-title":"Pediatrics"},{"key":"10.1016\/j.clp.2020.05.006_bib7","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.jpeds.2019.06.053","article-title":"Morbidity of persistent pulmonary hypertension of the newborn in the first year of life","volume":"213","author":"Steurer","year":"2019","journal-title":"J\u00a0Pediatr"},{"key":"10.1016\/j.clp.2020.05.006_bib8","doi-asserted-by":"crossref","first-page":"F554","DOI":"10.1136\/archdischild-2017-313778","article-title":"Persistent pulmonary hypertension of the newborn in extremely preterm infants: a Japanese cohort study","volume":"103","author":"Nakanishi","year":"2018","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"10.1016\/j.clp.2020.05.006_bib9","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1111\/ppe.12444","article-title":"Identification of gaps in the current knowledge on pulmonary hypertension in extremely preterm infants: a systematic review and meta-analysis","volume":"32","author":"Arjaans","year":"2018","journal-title":"Paediatr Perinat Epidemiol"},{"key":"10.1016\/j.clp.2020.05.006_bib10","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1164\/rccm.201803-0428OC","article-title":"Early pulmonary vascular disease in preterm infants is associated with late respiratory outcomes in childhood","volume":"199","author":"Mourani","year":"2019","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.clp.2020.05.006_bib11","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1038\/jp.2016.108","article-title":"Impact of pulmonary hypertension on neurodevelopmental outcome in preterm infants with bronchopulmonary dysplasia: a cohort study","volume":"36","author":"Nakanishi","year":"2016","journal-title":"J\u00a0Perinatol"},{"key":"10.1016\/j.clp.2020.05.006_bib12","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1161\/CIRCULATIONAHA.107.653576","article-title":"Right ventricular function in cardiovascular disease, part i: anatomy, physiology, aging, and functional assessment of the right ventricle","volume":"117","author":"Haddad","year":"2008","journal-title":"Circulation"},{"key":"10.1016\/j.clp.2020.05.006_bib13","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1007\/s00246-009-9390-9","article-title":"The development and structure of the ventricles in the human heart","volume":"30","author":"Henderson","year":"2009","journal-title":"Pediatr Cardiol"},{"key":"10.1016\/j.clp.2020.05.006_bib14","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1161\/CIRCRESAHA.116.302752","article-title":"Molecular regulation of cardiomyocyte differentiation","volume":"116","author":"Paige","year":"2015","journal-title":"Circ Res"},{"key":"10.1016\/j.clp.2020.05.006_bib15","doi-asserted-by":"crossref","first-page":"2489","DOI":"10.1093\/eurheartj\/ehr160","article-title":"Early detection of pulmonary vascular disease in pulmonary arterial hypertension: time to move forward","volume":"32","author":"Lau","year":"2011","journal-title":"Eur Heart J"},{"key":"10.1016\/j.clp.2020.05.006_bib16","doi-asserted-by":"crossref","first-page":"2162","DOI":"10.1007\/s10439-018-2089-4","article-title":"Region-specific microstructure in the neonatal ventricles of a porcine model","volume":"46","author":"Ahmad","year":"2018","journal-title":"Ann Biomed Eng"},{"key":"10.1016\/j.clp.2020.05.006_bib17","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1086\/689750","article-title":"Addressing the challenges of phenotyping pediatric pulmonary vascular disease","volume":"7","author":"Goss","year":"2017","journal-title":"Pulm Circ"},{"key":"10.1016\/j.clp.2020.05.006_bib18","doi-asserted-by":"crossref","first-page":"2037","DOI":"10.1161\/CIR.0000000000000329","article-title":"Pediatric pulmonary hypertension: guidelines from the American heart association and American Thoracic Society","volume":"132","author":"Abman","year":"2015","journal-title":"Circulation"},{"key":"10.1016\/j.clp.2020.05.006_bib19","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.01916-2018","article-title":"Paediatric pulmonary arterial hypertension: updates on definition, classification, diagnostics and management","volume":"53","author":"Rosenzweig","year":"2019","journal-title":"Eur Respir J"},{"key":"10.1016\/j.clp.2020.05.006_bib20","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1542\/pir.30.2.39","article-title":"Pulmonary hypertension","volume":"30","author":"Rothstein","year":"2009","journal-title":"Pediatr Rev"},{"key":"10.1016\/j.clp.2020.05.006_bib21","doi-asserted-by":"crossref","first-page":"e172","DOI":"10.1055\/s-0039-1688765","article-title":"Targeted neonatal echocardiography-guided therapy in vein of galen aneurysmal malformation: a report of two cases with a review of physiology and approach to management","volume":"09","author":"Giesinger","year":"2019","journal-title":"AJP Rep"},{"key":"10.1016\/j.clp.2020.05.006_bib22","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.earlhumdev.2018.11.006","article-title":"Left ventricular diastolic function influences right ventricular \u2014 pulmonary vascular coupling in premature infants","volume":"128","author":"Bussmann","year":"2018","journal-title":"Early Hum Dev"},{"key":"10.1016\/j.clp.2020.05.006_bib23","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.jpeds.2016.09.009","article-title":"Hypoxic-ischemic encephalopathy and therapeutic hypothermia: the hemodynamic perspective","volume":"180","author":"Giesinger","year":"2016","journal-title":"J\u00a0Pediatr"},{"key":"10.1016\/j.clp.2020.05.006_bib24","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/j.echo.2019.02.004","article-title":"Postnatal myocardial function in monochorionic diamniotic twins with twin-to-twin transfusion syndrome following selective laser photocoagulation of the communicating placental vessels","volume":"32","author":"Breatnach","year":"2019","journal-title":"J\u00a0Am Soc Echocardiogr"},{"key":"10.1016\/j.clp.2020.05.006_bib25","doi-asserted-by":"crossref","first-page":"e656","DOI":"10.1542\/peds.2008-0075","article-title":"Pulmonary vein stenosis: prematurity and associated conditions","volume":"122","author":"Drossner","year":"2008","journal-title":"Pediatrics"},{"key":"10.1016\/j.clp.2020.05.006_bib26","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.acvd.2012.12.005","article-title":"Pathophysiology of persistent pulmonary hypertension of the newborn: impact of the perinatal environment","volume":"106","author":"Storme","year":"2013","journal-title":"Arch Cardiovasc Dis"},{"key":"10.1016\/j.clp.2020.05.006_bib27","doi-asserted-by":"crossref","first-page":"e272","DOI":"10.1542\/peds.2006-3037","article-title":"Risk factors for persistent pulmonary hypertension of the newborn","volume":"120","author":"Hernandez-Diaz","year":"2007","journal-title":"Pediatrics"},{"key":"10.1016\/j.clp.2020.05.006_bib28","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.jpeds.2019.04.046","article-title":"Racial and ethnic differences in pediatric pulmonary hypertension: an analysis of the pediatric pulmonary hypertension network registry","volume":"211","author":"Ong","year":"2019","journal-title":"J\u00a0Pediatr"},{"key":"10.1016\/j.clp.2020.05.006_bib29","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1186\/s12931-019-1148-1","article-title":"Identification of genetic factors underlying persistent pulmonary hypertension of newborns in a cohort of Chinese neonates","volume":"20","author":"Liu","year":"2019","journal-title":"Respir Res"},{"issue":"10","key":"10.1016\/j.clp.2020.05.006_bib30","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1164\/rccm.201903-0583OC","article-title":"Impaired right ventricular function is associated with adverse outcome following hypoxic ischemic encephalopathy","volume":"200","author":"Giesinger","year":"2019","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.clp.2020.05.006_bib31","doi-asserted-by":"crossref","first-page":"1832","DOI":"10.1056\/NEJM200106143442404","article-title":"Neonatal pulmonary hypertension--urea-cycle intermediates, nitric oxide production, and carbamoyl-phosphate synthetase function","volume":"344","author":"Pearson","year":"2001","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.clp.2020.05.006_bib32","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1053\/j.semperi.2017.12.002","article-title":"An overview of medical ECMO for neonates","volume":"42","author":"Fletcher","year":"2018","journal-title":"Semin Perinatol"},{"key":"10.1016\/j.clp.2020.05.006_bib33","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.jpeds.2012.03.008","article-title":"Transient defect in nitric oxide generation after rupture of fetal membranes and responsiveness to inhaled nitric oxide in very preterm infants with hypoxic respiratory failure","volume":"161","author":"Aikio","year":"2012","journal-title":"J\u00a0Pediatr"},{"key":"10.1016\/j.clp.2020.05.006_bib34","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1038\/s41372-018-0303-8","article-title":"Death or resolution: the \"natural history\" of pulmonary hypertension in bronchopulmonary dysplasia","volume":"39","author":"Altit","year":"2019","journal-title":"J\u00a0Perinatol"},{"key":"10.1016\/j.clp.2020.05.006_bib35","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1016\/j.echo.2019.03.015","article-title":"Echocardiographic assessment of right ventricle afterload in preterm infants: maturational patterns of pulmonary artery acceleration time over the first year of age and implications for pulmonary hypertension","volume":"32","author":"Patel","year":"2019","journal-title":"J\u00a0Am Soc Echocardiogr"},{"key":"10.1016\/j.clp.2020.05.006_bib36","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.clp.2017.02.001","article-title":"Hemodynamic assessment and monitoring of premature infants","volume":"44","author":"El-Khuffash","year":"2017","journal-title":"Clin Perinatol"},{"key":"10.1016\/j.clp.2020.05.006_bib37","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.jacc.2016.10.047","article-title":"The relationship between the right ventricle and its load in pulmonary hypertension","volume":"69","author":"Vonk Noordegraaf","year":"2017","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.clp.2020.05.006_bib38","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1038\/s41372-018-0147-2","article-title":"Early diastolic dysfunction and respiratory morbidity in premature infants: an observational study","volume":"38","author":"Bussmann","year":"2018","journal-title":"J\u00a0Perinatol"},{"key":"10.1016\/j.clp.2020.05.006_bib39","doi-asserted-by":"crossref","first-page":"1708","DOI":"10.1038\/s41372-018-0241-5","article-title":"Right ventricular congestion in preterm neonates with chronic pulmonary hypertension","volume":"38","author":"Neary","year":"2018","journal-title":"J\u00a0Perinatol"},{"key":"10.1016\/j.clp.2020.05.006_bib40","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.jpeds.2017.05.029","article-title":"Evaluation and management of pulmonary hypertension in children with bronchopulmonary dysplasia","volume":"188","author":"Krishnan","year":"2017","journal-title":"J\u00a0Pediatr"},{"key":"10.1016\/j.clp.2020.05.006_bib41","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.clp.2015.11.013","article-title":"Pulmonary hypertension and pulmonary vasodilators","volume":"43","author":"Keller","year":"2016","journal-title":"Clin Perinatol"},{"key":"10.1016\/j.clp.2020.05.006_bib42","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1016\/j.echo.2016.08.013","article-title":"Pulmonary artery acceleration time provides a reliable estimate of invasive pulmonary hemodynamics in children","volume":"29","author":"Levy","year":"2016","journal-title":"J\u00a0Am Soc Echocardiogr"},{"key":"10.1016\/j.clp.2020.05.006_bib43","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1055\/s-0037-1598246","article-title":"Evidence of early pulmonary hypertension is associated with increased mortality in very low birth weight infants","volume":"34","author":"Berenz","year":"2017","journal-title":"Am J Perinatol"},{"key":"10.1016\/j.clp.2020.05.006_bib44","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.jpeds.2018.08.005","article-title":"Echocardiographic measurements of right ventricular mechanics in infants with bronchopulmonary dysplasia at 36\u00a0weeks postmenstrual age","volume":"203","author":"Ehrmann","year":"2018","journal-title":"J\u00a0Pediatr"},{"key":"10.1016\/j.clp.2020.05.006_bib45","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1161\/01.CIR.70.4.657","article-title":"Noninvasive estimation of right ventricular systolic pressure by Doppler ultrasound in patients with tricuspid regurgitation","volume":"70","author":"Yock","year":"1984","journal-title":"Circulation"},{"key":"10.1016\/j.clp.2020.05.006_bib46","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1016\/S0735-1097(02)02973-X","article-title":"A\u00a0simple method for noninvasive estimation of pulmonary vascular resistance","volume":"41","author":"Abbas","year":"2003","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.clp.2020.05.006_bib47","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1111\/echo.12738","article-title":"Echocardiographic assessment of pulmonary hypertension in infants with bronchopulmonary dysplasia: systematic review of literature and a proposed algorithm for assessment","volume":"32","author":"Nagiub","year":"2015","journal-title":"Echocardiography"},{"key":"10.1016\/j.clp.2020.05.006_bib48","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.jpeds.2018.04.051","article-title":"Cardiopulmonary adaptation during first day of life in human neonates","volume":"200","author":"Jain","year":"2018","journal-title":"J\u00a0Pediatr"},{"key":"10.1016\/j.clp.2020.05.006_bib49","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1016\/j.echo.2014.08.018","article-title":"A\u00a0comprehensive echocardiographic protocol for assessing neonatal right ventricular dimensions and function in the transitional period: normative data and z scores","volume":"27","author":"Jain","year":"2014","journal-title":"J\u00a0Am Soc Echocardiogr"},{"key":"10.1016\/j.clp.2020.05.006_bib50","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1542\/peds.2007-1583","article-title":"Clinical utility of echocardiography for the diagnosis and management of pulmonary vascular disease in young children with chronic lung disease","volume":"121","author":"Mourani","year":"2008","journal-title":"Pediatrics"},{"key":"10.1016\/j.clp.2020.05.006_bib51","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.jpeds.2019.10.034","article-title":"Risk assessment and monitoring of chronic pulmonary hypertension in premature infants","volume":"217","author":"Levy","year":"2019","journal-title":"J\u00a0Pediatr"},{"key":"10.1016\/j.clp.2020.05.006_bib52","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1111\/echo.14409","article-title":"Accuracy and reliability of qualitative echocardiography assessment of right ventricular size and function in neonates","volume":"36","author":"Smith","year":"2019","journal-title":"Echocardiography"},{"issue":"4","key":"10.1016\/j.clp.2020.05.006_bib53","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1159\/000445779","article-title":"Novel echocardiography methods in the functional assessment of the newborn heart","volume":"110","author":"Breatnach","year":"2016","journal-title":"Neonatology"},{"key":"10.1016\/j.clp.2020.05.006_bib54","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.jpeds.2018.02.006","article-title":"Evidence of echocardiographic markers of pulmonary vascular disease in asymptomatic preterm infants at one year of age","volume":"197","author":"Levy","year":"2018","journal-title":"J\u00a0Pediatr"},{"key":"10.1016\/j.clp.2020.05.006_bib55","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1038\/s41390-019-0293-z","article-title":"Future perspectives on the use of deformation analysis to identify the underlying pathophysiological basis for cardiovascular compromise in neonates","volume":"85","author":"Bussmann","year":"2019","journal-title":"Pediatr Res"},{"key":"10.1016\/j.clp.2020.05.006_bib56","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1161\/CIRCULATIONAHA.111.026591","article-title":"Survival in childhood pulmonary arterial hypertension: insights from the registry to evaluate early and long-term pulmonary arterial hypertension disease management","volume":"125","author":"Barst","year":"2012","journal-title":"Circulation"},{"key":"10.1016\/j.clp.2020.05.006_bib57","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1016\/j.echo.2018.04.004","article-title":"Right ventricular-pulmonary vascular interactions: an emerging role for pulmonary artery acceleration time by echocardiography in adults and children","volume":"31","author":"Levy","year":"2018","journal-title":"J\u00a0Am Soc Echocardiogr"},{"issue":"4","key":"10.1016\/j.clp.2020.05.006_bib58","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1016\/j.jcmg.2018.09.022","article-title":"A\u00a0novel noninvasive index to characterize right ventricle pulmonary arterial vascular coupling in children","volume":"12","author":"Levy","year":"2019","journal-title":"JACC Cardiovasc Imaging"},{"issue":"10","key":"10.1016\/j.clp.2020.05.006_bib59","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1016\/j.echo.2017.07.008","article-title":"Strain rate and its positive force-frequency relationship: further evidence from a premature infant cohort","volume":"30","author":"Breatnach","year":"2017","journal-title":"J\u00a0Am Soc Echocardiogr"},{"key":"10.1016\/j.clp.2020.05.006_bib60","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1002\/ppul.23391","article-title":"Association of BNP, NTproBNP, and early postnatal pulmonary hypertension in very preterm infants","volume":"51","author":"K\u00f6nig","year":"2016","journal-title":"Pediatr Pulmonol"},{"key":"10.1016\/j.clp.2020.05.006_bib61","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2431-14-68","article-title":"B-type natriuretic peptide and mortality in extremely low birth weight infants with pulmonary hypertension: a retrospective cohort analysis","volume":"14","author":"Cuna","year":"2014","journal-title":"BMC Pediatr"},{"key":"10.1016\/j.clp.2020.05.006_bib62","doi-asserted-by":"crossref","first-page":"1252","DOI":"10.1038\/s41372-018-0164-1","article-title":"NTproBNP as a surrogate biomarker for early screening of pulmonary hypertension in preterm infants with bronchopulmonary dysplasia","volume":"38","author":"Dasgupta","year":"2018","journal-title":"J\u00a0Perinatol"},{"key":"10.1016\/j.clp.2020.05.006_bib63","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1172\/jci.insight.93994","article-title":"Exosomal microRNA predicts and protects against severe bronchopulmonary dysplasia in extremely premature infants","volume":"3","author":"Lal","year":"2018","journal-title":"JCI Insight"},{"issue":"3","key":"10.1016\/j.clp.2020.05.006_bib64","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1159\/000442043","article-title":"Biochemical screening for pulmonary hypertension in preterm infants with bronchopulmonary dysplasia","volume":"109","author":"Montgomery","year":"2016","journal-title":"Neonatology"},{"key":"10.1016\/j.clp.2020.05.006_bib65","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1183\/09031936.00160307","article-title":"Biomarkers in pulmonary hypertension","volume":"32","author":"Warwick","year":"2008","journal-title":"Eur Respir J"},{"key":"10.1016\/j.clp.2020.05.006_bib66","doi-asserted-by":"crossref","first-page":"e0163904","DOI":"10.1371\/journal.pone.0163904","article-title":"Risk factors and clinical outcomes in preterm infants with pulmonary hypertension","volume":"11","author":"Collaco","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.clp.2020.05.006_bib67","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1164\/rccm.201409-1594OC","article-title":"Early pulmonary vascular disease in preterm infants at risk for bronchopulmonary dysplasia","volume":"191","author":"Mourani","year":"2015","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.clp.2020.05.006_bib68","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1097\/MOP.0000000000000490","article-title":"The evolution of disease","volume":"29","author":"Tracy","year":"2017","journal-title":"Curr Opin Pediatr"},{"key":"10.1016\/j.clp.2020.05.006_bib69","doi-asserted-by":"crossref","first-page":"75","DOI":"10.3390\/children4090075","article-title":"Diagnostic approach to pulmonary hypertension in premature neonates","volume":"4","author":"Kumar","year":"2017","journal-title":"Children"},{"key":"10.1016\/j.clp.2020.05.006_bib70","series-title":"Avery\u2019s neonatology: pathophysiology and management of the newborn","first-page":"457","article-title":"Hemodynamics","author":"McNamara","year":"2016"},{"issue":"4","key":"10.1016\/j.clp.2020.05.006_bib71","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD000399.pub2","article-title":"Nitric oxide for respiratory failure in infants born at or near term","author":"Finer","year":"2006","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.clp.2020.05.006_bib72","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S0140-6736(96)04100-1","article-title":"UK collaborative randomised trial of neonatal extracorporeal membrane oxygenation. UK Collaborative ECMO Trail Group","volume":"348","year":"1996","journal-title":"Lancet"},{"key":"10.1016\/j.clp.2020.05.006_bib73","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1097\/MAT.0000000000000603","article-title":"Pediatric extracorporeal life support Organization registry International report 2016","volume":"63","author":"Barbaro","year":"2017","journal-title":"ASAIO J"},{"key":"10.1016\/j.clp.2020.05.006_bib74","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.jpedsurg.2011.10.017","article-title":"Extracorporeal membrane oxygenation cannulation trends for pediatric respiratory failure and central nervous system injury","volume":"47","author":"Rollins","year":"2012","journal-title":"J\u00a0Pediatr Surg"},{"key":"10.1016\/j.clp.2020.05.006_bib75","doi-asserted-by":"crossref","first-page":"286","DOI":"10.4103\/2045-8932.83456","article-title":"A\u00a0consensus approach to the classification of pediatric pulmonary hypertensive vascular disease: report from the PVRI Pediatric Taskforce, Panama 2011","volume":"1","author":"Cerro","year":"2011","journal-title":"Pulm Circ"},{"key":"10.1016\/j.clp.2020.05.006_bib76","first-page":"1","article-title":"Hypoxic-ischemic encephalopathy. Fanaroff and Martin\u2019s neonatal-perinatal medicine","volume":"10","author":"Levene","year":"2016","journal-title":"Dis Fetus Infant"},{"key":"10.1016\/j.clp.2020.05.006_bib77","doi-asserted-by":"crossref","first-page":"e19","DOI":"10.1016\/j.jpeds.2010.11.008","article-title":"Pulmonary hypertension and the asphyxiated newborn","volume":"158","author":"Lapointe","year":"2011","journal-title":"J\u00a0Pediatr"},{"key":"10.1016\/j.clp.2020.05.006_bib78","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1542\/peds.106.1.92","article-title":"Cardiovascular changes during mild therapeutic hypothermia and rewarming in infants with hypoxic-ischemic encephalopathy","volume":"106","author":"Thoresen","year":"2000","journal-title":"Pediatrics"},{"key":"10.1016\/j.clp.2020.05.006_bib79","doi-asserted-by":"crossref","first-page":"e13","DOI":"10.1016\/j.jpeds.2010.11.007","article-title":"Functional echocardiography in assessment of the cardiovascular system in asphyxiated neonates","volume":"158","author":"Kluckow","year":"2011","journal-title":"J\u00a0Pediatr"},{"key":"10.1016\/j.clp.2020.05.006_bib80","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1038\/s41390-018-0075-z","article-title":"Application of neonatologist performed echocardiography in the assessment and management of neonatal heart failure unrelated to congenital heart disease","volume":"84","author":"Levy","year":"2018","journal-title":"Pediatr Res"},{"key":"10.1016\/j.clp.2020.05.006_bib81","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1007\/s00246-014-1033-0","article-title":"Speckle tracking and myocardial tissue imaging in infant of diabetic mother with gestational and pregestational diabetes","volume":"36","author":"Al-Biltagi","year":"2015","journal-title":"Pediatr Cardiol"},{"key":"10.1016\/j.clp.2020.05.006_bib82","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1038\/jp.2011.135","article-title":"Altered transitional circulation in infants of diabetic mothers with strict antenatal obstetric management: a functional echocardiography study","volume":"32","author":"Katheria","year":"2012","journal-title":"J\u00a0Perinatol"},{"key":"10.1016\/j.clp.2020.05.006_bib83","first-page":"A84","article-title":"Hemodynamics presentation of late-onset sepsis in the preterm newborns","volume":"35","author":"de waal","year":"2009","journal-title":"J\u00a0Paediatr Child Health"},{"key":"10.1016\/j.clp.2020.05.006_bib84","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1097\/PCC.0000000000000115","article-title":"Hemodynamic changes in preterm neonates with septic shock","volume":"15","author":"Saini","year":"2014","journal-title":"Pediatr Crit Care Med"},{"key":"10.1016\/j.clp.2020.05.006_bib85","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.jpeds.2017.09.046","article-title":"Infants born with down syndrome: burden of disease in the early neonatal period","volume":"193","author":"Martin","year":"2018","journal-title":"J\u00a0Pediatr"},{"key":"10.1016\/j.clp.2020.05.006_bib86","doi-asserted-by":"crossref","first-page":"e0159005","DOI":"10.1371\/journal.pone.0159005","article-title":"Increased lung expression of anti-angiogenic factors in down syndrome: potential role in abnormal lung vascular growth and the risk for pulmonary hypertension","volume":"11","author":"Galambos","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.clp.2020.05.006_bib87","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1038\/s41372-019-0354-5","article-title":"Cardiac mechanics in infants with Down syndrome in the early neonatal period","volume":"39","author":"Breatnach","year":"2019","journal-title":"J\u00a0Perinatol"}],"container-title":["Clinics in Perinatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0095510820300580?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0095510820300580?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T15:59:22Z","timestamp":1758815962000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0095510820300580"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9]]},"references-count":87,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,9]]}},"alternative-id":["S0095510820300580"],"URL":"https:\/\/doi.org\/10.1016\/j.clp.2020.05.006","relation":{},"ISSN":["0095-5108"],"issn-type":[{"value":"0095-5108","type":"print"}],"subject":[],"published":{"date-parts":[[2020,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Updates on Management for Acute and Chronic Phenotypes of Neonatal Pulmonary Hypertension","name":"articletitle","label":"Article Title"},{"value":"Clinics in Perinatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clp.2020.05.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}