{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T02:43:57Z","timestamp":1788921837682,"version":"build-2803163510"},"reference-count":37,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinics in Perinatology"],"published-print":{"date-parts":[[2022,3]]},"DOI":"10.1016\/j.clp.2021.11.001","type":"journal-article","created":{"date-parts":[[2022,1,21]],"date-time":"2022-01-21T17:09:39Z","timestamp":1642784979000},"page":"1-14","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"title":["Delirium in the Neonate"],"prefix":"10.1016","volume":"49","author":[{"given":"Samuel J.","family":"Adams","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alicia","family":"Sprecher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.clp.2021.11.001_bib1","series-title":"Diagnostic and statistical manual of mental disorders : DSM-5","year":"2013"},{"issue":"6","key":"10.1016\/j.clp.2021.11.001_bib2","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1007\/s00134-016-4344-1","article-title":"Clinical recommendations for pain, sedation, withdrawal and delirium assessment in critically ill infants and children: an ESPNIC position statement for healthcare professionals","volume":"42","author":"Harris","year":"2016","journal-title":"Intensive Care Med"},{"issue":"4","key":"10.1016\/j.clp.2021.11.001_bib3","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1017\/S1478951514000947","article-title":"Delirium screening anchored in child development: the Cornell assessment for pediatric delirium","volume":"13","author":"Silver","year":"2015","journal-title":"Palliat Support Care"},{"issue":"2","key":"10.1016\/j.clp.2021.11.001_bib4","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1891\/0730-0832\/11-T-727","article-title":"Delirium in the NICU: risk or reality?","volume":"40","author":"Liviskie","year":"2021","journal-title":"Neonatal Netw"},{"issue":"3","key":"10.1016\/j.clp.2021.11.001_bib5","doi-asserted-by":"crossref","first-page":"e20153369","DOI":"10.1542\/peds.2015-3369","article-title":"Detection and management of delirium in the neonatal unit: a case series","volume":"137","author":"Groves","year":"2016","journal-title":"Pediatrics"},{"issue":"3","key":"10.1016\/j.clp.2021.11.001_bib6","doi-asserted-by":"crossref","first-page":"e20151940","DOI":"10.1542\/peds.2015-1940","article-title":"Diagnosis and management of delirium in critically ill infants: case report and review","volume":"137","author":"Brahmbhatt","year":"2016","journal-title":"Pediatrics"},{"issue":"1","key":"10.1016\/j.clp.2021.11.001_bib7","doi-asserted-by":"crossref","first-page":"119","DOI":"10.3233\/NPM-1637","article-title":"A\u00a0case of infant delirium in the neonatal intensive care unit","volume":"10","author":"Edwards","year":"2017","journal-title":"J\u00a0Neonatal Perinatal Med"},{"issue":"6","key":"10.1016\/j.clp.2021.11.001_bib8","doi-asserted-by":"crossref","first-page":"e413","DOI":"10.1097\/PCC.0b013e31820ac2bf","article-title":"Recurrent delirium after surgery for congenital heart disease in an infant","volume":"12","author":"Madden","year":"2011","journal-title":"Pediatr Crit Care Med"},{"issue":"3","key":"10.1016\/j.clp.2021.11.001_bib9","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1016\/j.pcl.2013.02.010","article-title":"Pediatric delirium: monitoring and management in the pediatric intensive care unit","volume":"60","author":"Smith","year":"2013","journal-title":"Pediatr Clin North Am"},{"issue":"5","key":"10.1016\/j.clp.2021.11.001_bib10","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1097\/CCM.0000000000002324","article-title":"Delirium and mortality in critically ill children: epidemiology and outcomes of pediatric delirium","volume":"45","author":"Traube","year":"2017","journal-title":"Crit Care Med"},{"issue":"1","key":"10.1016\/j.clp.2021.11.001_bib11","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1097\/PCC.0000000000002126","article-title":"Delirium in a Tertiary PICU: risk factors and outcomes","volume":"21","author":"Dervan","year":"2020","journal-title":"Pediatr Crit Care Med"},{"issue":"4","key":"10.1016\/j.clp.2021.11.001_bib12","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1097\/CCM.0000000000002250","article-title":"Delirium in critically ill children: an international point prevalence study","volume":"45","author":"Traube","year":"2017","journal-title":"Crit Care Med"},{"issue":"12","key":"10.1016\/j.clp.2021.11.001_bib13","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1016\/j.jagp.2013.09.005","article-title":"Neuropathogenesis of delirium: review of current etiologic theories and common pathways","volume":"21","author":"Maldonado","year":"2013","journal-title":"Am J Geriatr Psychiatry"},{"issue":"3","key":"10.1016\/j.clp.2021.11.001_bib14","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1097\/CCM.0b013e3182a66b76","article-title":"Cornell Assessment of Pediatric Delirium: a valid, rapid, observational tool for screening delirium in the PICU","volume":"42","author":"Traube","year":"2014","journal-title":"Crit Care Med"},{"issue":"5","key":"10.1016\/j.clp.2021.11.001_bib15","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1016\/j.pcl.2017.06.009","article-title":"Delirium in pediatric critical care","volume":"64","author":"Patel","year":"2017","journal-title":"Pediatr Clin North Am"},{"issue":"2","key":"10.1016\/j.clp.2021.11.001_bib16","doi-asserted-by":"crossref","first-page":"e112","DOI":"10.1097\/PCC.0000000000001414","article-title":"Monitoring haloperidol plasma concentration and associated adverse events in critically ill children with delirium: first results of a clinical protocol aimed to monitor efficacy and safety","volume":"19","author":"Slooff","year":"2018","journal-title":"Pediatr Crit Care Med"},{"issue":"6","key":"10.1016\/j.clp.2021.11.001_bib17","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1007\/s00134-007-0637-8","article-title":"Pediatric delirium in critical illness: phenomenology, clinical correlates and treatment response in 40 cases in the pediatric intensive care unit","volume":"33","author":"Schieveld","year":"2007","journal-title":"Intensive Care Med"},{"issue":"2","key":"10.1016\/j.clp.2021.11.001_bib18","first-page":"81","article-title":"Antipsychotic use in the prevention and treatment of intensive care unit delirium in pediatric patients","volume":"25","author":"Capino","year":"2020","journal-title":"J\u00a0Pediatr Pharmacol Ther"},{"issue":"9","key":"10.1016\/j.clp.2021.11.001_bib19","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1089\/cap.2015.0093","article-title":"Evaluation of the safety of quetiapine in treating delirium in critically ill children: a retrospective review","volume":"25","author":"Joyce","year":"2015","journal-title":"J\u00a0Child Adolesc Psychopharmacol"},{"issue":"5","key":"10.1016\/j.clp.2021.11.001_bib20","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1177\/1060028019891969","article-title":"An evaluation of risperidone dosing for pediatric delirium in children less than or equal to 2 years of age","volume":"54","author":"Campbell","year":"2020","journal-title":"Ann Pharmacother"},{"issue":"7","key":"10.1016\/j.clp.2021.11.001_bib21","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1097\/CCM.0000000000001622","article-title":"Dexmedetomidine for the treatment of hyperactive delirium refractory to haloperidol in nonintubated ICU patients: a nonrandomized controlled trial","volume":"44","author":"Carrasco","year":"2016","journal-title":"Crit Care Med"},{"issue":"3","key":"10.1016\/j.clp.2021.11.001_bib22","doi-asserted-by":"crossref","first-page":"R75","DOI":"10.1186\/cc7890","article-title":"Dexmedetomidine vs. haloperidol in delirious, agitated, intubated patients: a randomised open-label trial","volume":"13","author":"Reade","year":"2009","journal-title":"Crit Care"},{"key":"10.1016\/j.clp.2021.11.001_bib23","unstructured":"(U.S.). NLoM. Effects of Dexmedetomidine on Delirium Duration of Non-intubated ICU Patients (4D Trial). In: Available at: https:\/\/ClinicalTrials.gov\/show\/NCT03317067. Accessed June 22, 2021."},{"issue":"1","key":"10.1016\/j.clp.2021.11.001_bib24","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1186\/s13063-018-2656-x","article-title":"Effects of dexmedetomidine on delirium duration of non-intubated ICU patients (4D trial): study protocol for a randomized trial","volume":"19","author":"Louis","year":"2018","journal-title":"Trials"},{"issue":"3","key":"10.1016\/j.clp.2021.11.001_bib25","first-page":"252","article-title":"Dexmedetomidine versus standard therapy with fentanyl for sedation in mechanically ventilated premature neonates","volume":"17","author":"O'Mara","year":"2012","journal-title":"J\u00a0Pediatr Pharmacol Ther"},{"key":"10.1016\/j.clp.2021.11.001_bib26","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.pediatrneurol.2019.02.012","article-title":"Gabapentin use for hospitalized neonates","volume":"97","author":"Abdi","year":"2019","journal-title":"Pediatr Neurol"},{"key":"10.1016\/j.clp.2021.11.001_bib27","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/j.jpeds.2015.10.013","article-title":"Gabapentin use in the neonatal intensive care unit","volume":"169","author":"Edwards","year":"2016","journal-title":"J\u00a0Pediatr"},{"issue":"1","key":"10.1016\/j.clp.2021.11.001_bib28","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.coph.2005.11.003","article-title":"The mechanisms of action of gabapentin and pregabalin","volume":"6","author":"Sills","year":"2006","journal-title":"Curr Opin Pharmacol"},{"issue":"5","key":"10.1016\/j.clp.2021.11.001_bib29","doi-asserted-by":"crossref","first-page":"e91197","DOI":"10.5812\/aapm.91197","article-title":"Gabapentin in improvement of procedural sedation and analgesia in oncologic pediatric patients: a clinical trial","volume":"9","author":"Pinto Filho","year":"2019","journal-title":"Anesth Pain Med"},{"issue":"1","key":"10.1016\/j.clp.2021.11.001_bib30","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1186\/s12871-018-0533-5","article-title":"The role of Gabapentin oral solution in decreasing desflurane associated emergence agitation and delirium in children after stabismus surgery, a prospective randomized double-blind study","volume":"18","author":"Badawy","year":"2018","journal-title":"BMC Anesthesiol"},{"issue":"4","key":"10.1016\/j.clp.2021.11.001_bib31","first-page":"361","article-title":"Evaluation of melatonin practices for delirium in pediatric critically ill patients","volume":"26","author":"Laudone","year":"2021","journal-title":"J\u00a0Pediatr Pharmacol Ther"},{"issue":"5","key":"10.1016\/j.clp.2021.11.001_bib32","first-page":"e8335","article-title":"Perspective on melatonin use for sleep problems in autism and attention-deficit hyperactivity disorder: a systematic review of randomized clinical trials","volume":"12","author":"Parvataneni","year":"2020","journal-title":"Cureus"},{"issue":"4","key":"10.1016\/j.clp.2021.11.001_bib33","article-title":"Sleep and delirium in pediatric critical illness: what is the relationship?","volume":"6","author":"Calandriello","year":"2018","journal-title":"Med Sci (Basel)"},{"issue":"3","key":"10.1016\/j.clp.2021.11.001_bib34","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1093\/bja\/aew477","article-title":"Paediatric emergence delirium: a comprehensive review and interpretation of the literature","volume":"118","author":"Mason","year":"2017","journal-title":"Br J Anaesth"},{"issue":"9","key":"10.1016\/j.clp.2021.11.001_bib37","first-page":"1847","article-title":"Current state of analgesia and sedation in the pediatric intensive care unit","volume":"10","author":"Egbuta","year":"2021","journal-title":"J\u00a0Clin Med"},{"issue":"12","key":"10.1016\/j.clp.2021.11.001_bib38","doi-asserted-by":"crossref","first-page":"1793","DOI":"10.1634\/theoncologist.2011-0130","article-title":"Survival prediction for terminally ill cancer patients: revision of the palliative prognostic score with incorporation of delirium","volume":"16","author":"Scarpi","year":"2011","journal-title":"Oncologist"},{"issue":"12","key":"10.1016\/j.clp.2021.11.001_bib39","doi-asserted-by":"crossref","first-page":"2311","DOI":"10.1097\/CCM.0b013e3181f85759","article-title":"Delirium duration and mortality in lightly sedated, mechanically ventilated intensive care patients","volume":"38","author":"Shehabi","year":"2010","journal-title":"Crit Care Med"}],"container-title":["Clinics in Perinatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0095510821000993?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0095510821000993?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T15:58:19Z","timestamp":1758815899000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0095510821000993"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3]]},"references-count":37,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,3]]}},"alternative-id":["S0095510821000993"],"URL":"https:\/\/doi.org\/10.1016\/j.clp.2021.11.001","relation":{},"ISSN":["0095-5108"],"issn-type":[{"value":"0095-5108","type":"print"}],"subject":[],"published":{"date-parts":[[2022,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Delirium in the Neonate","name":"articletitle","label":"Article Title"},{"value":"Clinics in Perinatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.clp.2021.11.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}