{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T21:47:32Z","timestamp":1793051252832,"version":"4.5.0"},"reference-count":59,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2015,6,1]],"date-time":"2015-06-01T00:00:00Z","timestamp":1433116800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,5,6]],"date-time":"2015-05-06T00:00:00Z","timestamp":1430870400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Metabolism"],"published-print":{"date-parts":[[2015,6]]},"DOI":"10.1016\/j.cmet.2015.05.007","type":"journal-article","created":{"date-parts":[[2015,6,2]],"date-time":"2015-06-02T16:02:02Z","timestamp":1433260922000},"page":"834-844","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":453,"title":["The Opa1-Dependent Mitochondrial Cristae Remodeling Pathway Controls Atrophic, Apoptotic, and Ischemic Tissue Damage"],"prefix":"10.1016","volume":"21","author":[{"given":"Tatiana","family":"Varanita","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria\u00a0Eugenia","family":"Soriano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanina","family":"Romanello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tania","family":"Zaglia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rub\u00e9n","family":"Quintana-Cabrera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina","family":"Semenzato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberta","family":"Menab\u00f2","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronica","family":"Costa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriele","family":"Civiletto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola","family":"Pesce","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Viscomi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"Zeviani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio","family":"Di\u00a0Lisa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Mongillo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Sandri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Scorrano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cmet.2015.05.007_bib1","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1093\/cvr\/cvr015","article-title":"Mitochondrial adaptations to physiological vs. pathological cardiac hypertrophy","volume":"90","author":"Abel","year":"2011","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.cmet.2015.05.007_bib2","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1152\/japplphysiol.00768.2006","article-title":"Effect of denervation on mitochondrially mediated apoptosis in skeletal muscle","volume":"102","author":"Adhihetty","year":"2007","journal-title":"J.\u00a0Appl. Physiol."},{"key":"10.1016\/j.cmet.2015.05.007_bib3","doi-asserted-by":"crossref","first-page":"3274","DOI":"10.2337\/diabetes.53.12.3274","article-title":"Genetic determinants of energy expenditure and insulin resistance in diet-induced obesity in mice","volume":"53","author":"Almind","year":"2004","journal-title":"Diabetes"},{"key":"10.1016\/j.cmet.2015.05.007_bib4","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1083\/jcb.201308006","article-title":"The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission","volume":"204","author":"Anand","year":"2014","journal-title":"J.\u00a0Cell Biol."},{"key":"10.1016\/j.cmet.2015.05.007_bib5","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1002\/embj.201386474","article-title":"Stress-induced OMA1 activation and autocatalytic turnover regulate OPA1-dependent mitochondrial dynamics","volume":"33","author":"Baker","year":"2014","journal-title":"EMBO J."},{"key":"10.1016\/j.cmet.2015.05.007_bib6","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1161\/01.RES.78.5.821","article-title":"Binding of cytosolic proteins to myofibrils in ischemic rat hearts","volume":"78","author":"Barbato","year":"1996","journal-title":"Circ. Res."},{"key":"10.1016\/j.cmet.2015.05.007_bib7","doi-asserted-by":"crossref","first-page":"18558","DOI":"10.1074\/jbc.C500089200","article-title":"Properties of the permeability transition pore in mitochondria devoid of Cyclophilin D","volume":"280","author":"Basso","year":"2005","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.cmet.2015.05.007_bib8","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.bbabio.2004.09.006","article-title":"Clinical and molecular findings in children with complex I deficiency","volume":"1659","author":"Bugiani","year":"2004","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.cmet.2015.05.007_bib9","doi-asserted-by":"crossref","first-page":"6848","DOI":"10.2174\/138161281939131127110701","article-title":"Mitochondrial dynamics: an emerging paradigm in ischemia-reperfusion injury","volume":"19","author":"Calo","year":"2013","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.cmet.2015.05.007_bib10","doi-asserted-by":"crossref","first-page":"15803","DOI":"10.1073\/pnas.0808249105","article-title":"Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria","volume":"105","author":"Cereghetti","year":"2008","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cmet.2015.05.007_bib11","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1083\/jcb.200211046","article-title":"Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development","volume":"160","author":"Chen","year":"2003","journal-title":"J.\u00a0Cell Biol."},{"key":"10.1016\/j.cmet.2015.05.007_bib12","doi-asserted-by":"crossref","first-page":"15927","DOI":"10.1073\/pnas.0407043101","article-title":"OPA1 requires mitofusin 1 to promote mitochondrial fusion","volume":"101","author":"Cipolat","year":"2004","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cmet.2015.05.007_bib13","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.cell.2006.06.021","article-title":"Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling","volume":"126","author":"Cipolat","year":"2006","journal-title":"Cell"},{"key":"10.1016\/j.cmet.2015.05.007_bib14","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1016\/j.cmet.2015.04.016","article-title":"Opa1 overexpression ameliorates the phenotype of two mitochondrial disease mouse models","volume":"21","author":"Civiletto","year":"2015","journal-title":"Cell Metab."},{"key":"10.1016\/j.cmet.2015.05.007_bib15","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.cell.2013.08.032","article-title":"Mitochondrial cristae shape determines respiratory chain supercomplexes assembly and respiratory efficiency","volume":"155","author":"Cogliati","year":"2013","journal-title":"Cell"},{"key":"10.1016\/j.cmet.2015.05.007_bib16","doi-asserted-by":"crossref","DOI":"10.3791\/3039","article-title":"The application of permanent middle cerebral artery ligation in the mouse","author":"Colak","year":"2011","journal-title":"J.\u00a0Vis. Exp."},{"key":"10.1016\/j.cmet.2015.05.007_bib17","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/S0092-8674(04)00046-7","article-title":"Cell death: critical control points","volume":"116","author":"Danial","year":"2004","journal-title":"Cell"},{"key":"10.1016\/j.cmet.2015.05.007_bib18","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1038\/nature01825","article-title":"BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis","volume":"424","author":"Danial","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.cmet.2015.05.007_bib19","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1093\/hmg\/ddm079","article-title":"Opa1 deficiency in a mouse model of autosomal dominant optic atrophy impairs mitochondrial morphology, optic nerve structure and visual function","volume":"16","author":"Davies","year":"2007","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.cmet.2015.05.007_bib20","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1007\/s10741-010-9166-6","article-title":"Role of autophagy in heart failure associated with aging","volume":"15","author":"De Meyer","year":"2010","journal-title":"Heart Fail. Rev."},{"key":"10.1016\/j.cmet.2015.05.007_bib21","doi-asserted-by":"crossref","first-page":"2656","DOI":"10.1056\/NEJMra022567","article-title":"Mitochondrial respiratory-chain diseases","volume":"348","author":"DiMauro","year":"2003","journal-title":"N.\u00a0Engl. J. Med."},{"key":"10.1016\/j.cmet.2015.05.007_bib22","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1016\/j.cardiores.2004.03.027","article-title":"Gender modulates cardiac phenotype development in genetically modified mice","volume":"63","author":"Du","year":"2004","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.cmet.2015.05.007_bib23","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1038\/sj.bjp.0707353","article-title":"Divergence of hypertrophic growth and fetal gene profile: the influence of beta-blockers","volume":"152","author":"Du","year":"2007","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.cmet.2015.05.007_bib24","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/S1534-5807(01)00055-7","article-title":"The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis","volume":"1","author":"Frank","year":"2001","journal-title":"Dev. Cell"},{"key":"10.1016\/j.cmet.2015.05.007_bib25","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1007\/s10495-008-0300-z","article-title":"Bcl2 family proteins in carcinogenesis and the treatment of cancer","volume":"14","author":"Frenzel","year":"2009","journal-title":"Apoptosis"},{"key":"10.1016\/j.cmet.2015.05.007_bib26","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/S0968-0004(00)01609-1","article-title":"The internal structure of mitochondria","volume":"25","author":"Frey","year":"2000","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/j.cmet.2015.05.007_bib27","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.cell.2006.06.025","article-title":"OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion","volume":"126","author":"Frezza","year":"2006","journal-title":"Cell"},{"key":"10.1016\/j.cmet.2015.05.007_bib28","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1038\/nprot.2006.478","article-title":"Organelle isolation: functional mitochondria from mouse liver, muscle and cultured fibroblasts","volume":"2","author":"Frezza","year":"2007","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.cmet.2015.05.007_bib29","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1034\/j.1600-0854.2001.1r008.x","article-title":"The many shapes of mitochondrial membranes","volume":"2","author":"Griparic","year":"2001","journal-title":"Traffic"},{"key":"10.1016\/j.cmet.2015.05.007_bib30","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1083\/jcb.30.2.269","article-title":"Ultrastructural bases for metabolically linked mechanical activity in mitochondria. I. Reversible ultrastructural changes with change in metabolic steady state in isolated liver mitochondria","volume":"30","author":"Hackenbrock","year":"1966","journal-title":"J.\u00a0Cell Biol."},{"key":"10.1016\/j.cmet.2015.05.007_bib31","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1038\/ng1270","article-title":"Mitochondrial dysfunction and apoptosis in myopathic mice with collagen VI deficiency","volume":"35","author":"Irwin","year":"2003","journal-title":"Nat. Genet."},{"key":"10.1016\/j.cmet.2015.05.007_bib32","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1038\/embor.2010.50","article-title":"The BH3-only Bnip3 binds to the dynamin Opa1 to promote mitochondrial fragmentation and apoptosis by distinct mechanisms","volume":"11","author":"Landes","year":"2010","journal-title":"EMBO Rep."},{"key":"10.1016\/j.cmet.2015.05.007_bib33","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1083\/jcb.144.5.883","article-title":"The release of cytochrome c from mitochondria during apoptosis of NGF-deprived sympathetic neurons is a reversible event","volume":"144","author":"Martinou","year":"1999","journal-title":"J.\u00a0Cell Biol."},{"key":"10.1016\/j.cmet.2015.05.007_bib34","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1152\/physrev.00024.2007","article-title":"Mechanisms underlying acute protection from cardiac ischemia-reperfusion injury","volume":"88","author":"Murphy","year":"2008","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.cmet.2015.05.007_bib35","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1038\/364806a0","article-title":"Lethal effect of the anti-Fas antibody in mice","volume":"364","author":"Ogasawara","year":"1993","journal-title":"Nature"},{"key":"10.1016\/j.cmet.2015.05.007_bib36","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1002\/iub.1180","article-title":"Cell death in the myocardium: my heart won\u2019t go on","volume":"65","author":"Orogo","year":"2013","journal-title":"IUBMB Life"},{"key":"10.1016\/j.cmet.2015.05.007_bib37","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1038\/embor.2011.54","article-title":"MiD49 and MiD51, new components of the mitochondrial fission machinery","volume":"12","author":"Palmer","year":"2011","journal-title":"EMBO Rep."},{"key":"10.1016\/j.cmet.2015.05.007_bib38","first-page":"2111","article-title":"A Bcl-xL transgene promotes malignant conversion of chemically initiated skin papillomas","volume":"58","author":"Pena","year":"1998","journal-title":"Cancer Res."},{"key":"10.1016\/j.cmet.2015.05.007_bib39","doi-asserted-by":"crossref","first-page":"2389","DOI":"10.1152\/japplphysiol.01202.2006","article-title":"Oxidative stress and disuse muscle atrophy","volume":"102","author":"Powers","year":"2007","journal-title":"J.\u00a0Appl. Physiol."},{"key":"10.1016\/j.cmet.2015.05.007_bib40","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1111\/j.1469-7793.2000.00037.x","article-title":"Mitochondria as all-round players of the calcium game","volume":"529","author":"Rizzuto","year":"2000","journal-title":"J.\u00a0Physiol."},{"key":"10.1016\/j.cmet.2015.05.007_bib41","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1084\/jem.183.3.1031","article-title":"A bcl-2 transgene expressed in hepatocytes protects mice from fulminant liver destruction but not from rapid death induced by anti-Fas antibody injection","volume":"183","author":"Rodriguez","year":"1996","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.cmet.2015.05.007_bib42","doi-asserted-by":"crossref","first-page":"1774","DOI":"10.1038\/emboj.2010.60","article-title":"Mitochondrial fission and remodelling contributes to muscle atrophy","volume":"29","author":"Romanello","year":"2010","journal-title":"EMBO J."},{"key":"10.1016\/j.cmet.2015.05.007_bib43","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1152\/physiol.00041.2007","article-title":"Signaling in muscle atrophy and hypertrophy","volume":"23","author":"Sandri","year":"2008","journal-title":"Physiology (Bethesda)"},{"key":"10.1016\/j.cmet.2015.05.007_bib44","doi-asserted-by":"crossref","first-page":"2121","DOI":"10.1016\/j.biocel.2013.04.023","article-title":"Protein breakdown in muscle wasting: role of autophagy-lysosome and ubiquitin-proteasome","volume":"45","author":"Sandri","year":"2013","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.cmet.2015.05.007_bib45","doi-asserted-by":"crossref","first-page":"16260","DOI":"10.1073\/pnas.0607795103","article-title":"PGC-1alpha protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription","volume":"103","author":"Sandri","year":"2006","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cmet.2015.05.007_bib46","doi-asserted-by":"crossref","first-page":"2763","DOI":"10.1242\/jcs.00479","article-title":"Mitofusin-1 protein is a generally expressed mediator of mitochondrial fusion in mammalian cells","volume":"116","author":"Santel","year":"2003","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.cmet.2015.05.007_bib47","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/0076-6879(95)60137-6","article-title":"Native electrophoresis for isolation of mitochondrial oxidative phosphorylation protein complexes","volume":"260","author":"Sch\u00e4gger","year":"1995","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.cmet.2015.05.007_bib48","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/S0076-6879(96)64045-2","article-title":"Cytochemistry and immunocytochemistry of mitochondria in tissue sections","volume":"264","author":"Sciacco","year":"1996","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.cmet.2015.05.007_bib49","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/S1534-5807(01)00116-2","article-title":"A distinct pathway remodels mitochondrial cristae and mobilizes cytochrome c during apoptosis","volume":"2","author":"Scorrano","year":"2002","journal-title":"Dev. Cell"},{"key":"10.1016\/j.cmet.2015.05.007_bib50","doi-asserted-by":"crossref","first-page":"2533","DOI":"10.1242\/jcs.070490","article-title":"New insights into the role of mitochondria in aging: mitochondrial dynamics and more","volume":"123","author":"Seo","year":"2010","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.cmet.2015.05.007_bib51","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1113\/jphysiol.2004.081083","article-title":"Mitochondria-associated apoptotic signalling in denervated rat skeletal muscle","volume":"565","author":"Siu","year":"2005","journal-title":"J.\u00a0Physiol."},{"key":"10.1016\/j.cmet.2015.05.007_bib52","first-page":"2922","article-title":"The expanding role of mitochondria in apoptosis","volume":"15","author":"Wang","year":"2001","journal-title":"Genes Dev."},{"key":"10.1016\/j.cmet.2015.05.007_bib53","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.cell.2011.11.030","article-title":"The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways","volume":"148","author":"Wang","year":"2012","journal-title":"Cell"},{"key":"10.1016\/j.cmet.2015.05.007_bib54","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.tem.2009.03.007","article-title":"The changing shape of mitochondrial apoptosis","volume":"20","author":"Wasilewski","year":"2009","journal-title":"Trends Endocrinol. Metab."},{"key":"10.1016\/j.cmet.2015.05.007_bib55","doi-asserted-by":"crossref","first-page":"2060","DOI":"10.1101\/gad.14.16.2060","article-title":"tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c","volume":"14","author":"Wei","year":"2000","journal-title":"Genes Dev."},{"key":"10.1016\/j.cmet.2015.05.007_bib56","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1126\/science.1059108","article-title":"Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death","volume":"292","author":"Wei","year":"2001","journal-title":"Science"},{"key":"10.1016\/j.cmet.2015.05.007_bib57","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/j.molcel.2008.07.010","article-title":"Opa1-mediated cristae opening is Bax\/Bak and BH3 dependent, required for apoptosis, and independent of Bak oligomerization","volume":"31","author":"Yamaguchi","year":"2008","journal-title":"Mol. Cell"},{"key":"10.1016\/j.cmet.2015.05.007_bib58","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1038\/23730","article-title":"Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis","volume":"400","author":"Yin","year":"1999","journal-title":"Nature"},{"key":"10.1016\/j.cmet.2015.05.007_bib59","doi-asserted-by":"crossref","first-page":"2235","DOI":"10.1091\/mbc.E10-12-0933","article-title":"The dynamin-related GTPase Opa1 is required for glucose-stimulated ATP production in pancreatic beta cells","volume":"22","author":"Zhang","year":"2011","journal-title":"Mol. Biol. Cell"}],"container-title":["Cell Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1550413115002193?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1550413115002193?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,5,10]],"date-time":"2022-05-10T16:30:47Z","timestamp":1652200247000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1550413115002193"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,6]]},"references-count":59,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,6]]}},"alternative-id":["S1550413115002193"],"URL":"https:\/\/doi.org\/10.1016\/j.cmet.2015.05.007","relation":{},"ISSN":["1550-4131"],"issn-type":[{"value":"1550-4131","type":"print"}],"subject":[],"published":{"date-parts":[[2015,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The Opa1-Dependent Mitochondrial Cristae Remodeling Pathway Controls Atrophic, Apoptotic, and Ischemic Tissue Damage","name":"articletitle","label":"Article Title"},{"value":"Cell Metabolism","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cmet.2015.05.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.cmet.2015.04.016","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 The Authors. Published by Cell Press","name":"copyright","label":"Copyright"}]}}