{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T14:33:04Z","timestamp":1790087584162,"version":"4.0.1"},"reference-count":10,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000884","name":"Cancer Research Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000884","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Metabolism"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.cmet.2025.10.018","type":"journal-article","created":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T16:17:33Z","timestamp":1764692253000},"page":"2296-2297","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Adipose whispers to mast cells for accelerating immune evasion in pancreatic cancer"],"prefix":"10.1016","volume":"37","author":[{"given":"Lor\u00e8ne","family":"Rousseau","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping-Chih","family":"Ho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cmet.2025.10.018_bib1","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1002\/oby.21003","article-title":"Adipose tissue as an immunological organ","volume":"23","author":"Grant","year":"2015","journal-title":"Obesity"},{"key":"10.1016\/j.cmet.2025.10.018_bib2","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1016\/j.cmet.2009.09.012","article-title":"A Negative Regulatory Pathway of GLUT4 Trafficking in Adipocyte: New Function of RIP140 in the Cytoplasm via AS160","volume":"10","author":"Ho","year":"2009","journal-title":"Cell Metab."},{"key":"10.1016\/j.cmet.2025.10.018_bib3","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1038\/s41577-024-01103-8","article-title":"Adipokines: masterminds of metabolic inflammation","volume":"25","author":"Tilg","year":"2025","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.cmet.2025.10.018_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.bcp.2024.116116","article-title":"The pathophysiology of visceral adipose tissues in cardiometabolic diseases","volume":"222","author":"Lee","year":"2024","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.cmet.2025.10.018_bib5","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1186\/s12964-021-00789-w","article-title":"Immune checkpoint inhibition for pancreatic ductal adenocarcinoma: limitations and prospects: a systematic review","volume":"19","author":"Li","year":"2021","journal-title":"Cell Commun. Signal."},{"key":"10.1016\/j.cmet.2025.10.018_bib6","doi-asserted-by":"crossref","first-page":"djw304","DOI":"10.1093\/jnci\/djw304","article-title":"PD-L1 Expression in Pancreatic Cancer","volume":"109","author":"Zheng","year":"2017","journal-title":"J. Natl. Cancer Inst."},{"key":"10.1016\/j.cmet.2025.10.018_bib7","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1016\/j.cell.2020.03.062","article-title":"Endocrine-Exocrine Signaling Drives Obesity-Associated Pancreatic Ductal Adenocarcinoma","volume":"181","author":"Chung","year":"2020","journal-title":"Cell"},{"key":"10.1016\/j.cmet.2025.10.018_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2025.115732","article-title":"Exploring adipose tissue-derived extracellular vesicles in inter-organ crosstalk: Implications for metabolic regulation and adipose tissue function","volume":"44","author":"Le Lay","year":"2025","journal-title":"Cell Rep."},{"key":"10.1016\/j.cmet.2025.10.018_bib9","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.imlet.2019.03.011","article-title":"Mast cells: A double-edged sword in cancer","volume":"209","author":"Derakhshani","year":"2019","journal-title":"Immunol. Lett."},{"key":"10.1016\/j.cmet.2025.10.018_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.esmoop.2025.104528","article-title":"ESMO Clinical Practice Guideline Express Update on the management of metastatic pancreatic cancer","volume":"10","author":"Conroy","year":"2025","journal-title":"ESMO Open"}],"container-title":["Cell Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1550413125004784?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1550413125004784?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T21:29:58Z","timestamp":1783027798000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1550413125004784"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":10,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["S1550413125004784"],"URL":"https:\/\/doi.org\/10.1016\/j.cmet.2025.10.018","relation":{},"ISSN":["1550-4131"],"issn-type":[{"value":"1550-4131","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Adipose whispers to mast cells for accelerating immune evasion in pancreatic cancer","name":"articletitle","label":"Article Title"},{"value":"Cell Metabolism","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cmet.2025.10.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.cmet.2025.10.015","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}