{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T03:59:22Z","timestamp":1789185562214,"version":"build-2803163510"},"reference-count":20,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2017,4,1]],"date-time":"2017-04-01T00:00:00Z","timestamp":1491004800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T00:00:00Z","timestamp":1522540800000},"content-version":"vor","delay-in-days":365,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Microbiology and Infection"],"published-print":{"date-parts":[[2017,4]]},"DOI":"10.1016\/j.cmi.2017.02.036","type":"journal-article","created":{"date-parts":[[2017,3,6]],"date-time":"2017-03-06T22:03:27Z","timestamp":1488837807000},"page":"242-246","source":"Crossref","is-referenced-by-count":25,"title":["A double-blind randomized controlled trial of ibuprofen compared to placebo for uncomplicated cellulitis of the upper or lower limb"],"prefix":"10.1016","volume":"23","author":[{"given":"J.S.","family":"Davis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Mackrow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Binks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.","family":"Fletcher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Dettwiller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Marshall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Day","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.","family":"Pratt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.Y.C.","family":"Tong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cmi.2017.02.036_bib1","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1001\/jama.2016.8825","article-title":"Cellulitis: a review","volume":"316","author":"Raff","year":"2016","journal-title":"JAMA"},{"key":"10.1016\/j.cmi.2017.02.036_bib2","first-page":"CD004299","article-title":"Interventions for cellulitis and erysipelas","volume":"6","author":"Kilburn","year":"2010","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.cmi.2017.02.036_bib3","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1056\/NEJM199601253340407","article-title":"Streptococcal infections of skin and soft tissues","volume":"334","author":"Bisno","year":"1996","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.cmi.2017.02.036_bib4","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1001\/archderm.1987.01660280070025","article-title":"Early detection of streptococcal group antigens in skin samples by latex particle agglutination","volume":"123","author":"Bernard","year":"1987","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.cmi.2017.02.036_bib5","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1001\/archsurg.1995.01430070108024","article-title":"Clinical features and aerobic and anaerobic microbiological characteristics of cellulitis","volume":"130","author":"Brook","year":"1995","journal-title":"Arch Surg"},{"key":"10.1016\/j.cmi.2017.02.036_bib6","doi-asserted-by":"crossref","first-page":"E17","DOI":"10.1086\/317530","article-title":"Possible role of cellular immunity: a case of cellulitis","volume":"32","author":"Baddour","year":"2001","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.cmi.2017.02.036_bib7","doi-asserted-by":"crossref","first-page":"377","DOI":"10.3109\/00365549709011834","article-title":"Antibiotic and prednisolone therapy of erysipelas: a randomized, double blind, placebo-controlled study","volume":"29","author":"Bergkvist","year":"1997","journal-title":"Scand J Infect Dis"},{"key":"10.1016\/j.cmi.2017.02.036_bib8","first-page":"177","article-title":"Rapid resolution of cellulitis in patients managed with combination antibiotic and anti-inflammatory therapy","volume":"75","author":"Dall","year":"2005","journal-title":"Cutis"},{"key":"10.1016\/j.cmi.2017.02.036_bib9","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.1378\/chest.101.6.1644","article-title":"Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP\/SCCM Consensus Conference Committee. American College of Chest Physicians\/Society of Critical Care Medicine","volume":"101","author":"Bone","year":"1992","journal-title":"Chest"},{"key":"10.1016\/j.cmi.2017.02.036_bib10","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1111\/j.1742-1241.2008.01988.x","article-title":"The efficacy and safety of daptomycin vs. vancomycin for the treatment of cellulitis and erysipelas","volume":"63","author":"Pertel","year":"2009","journal-title":"Int J Clin Pract"},{"key":"10.1016\/j.cmi.2017.02.036_bib11","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1136\/emj.2004.019869","article-title":"Flucloxacillin alone or combined with benzylpenicillin to treat lower limb cellulitis: a randomised controlled trial","volume":"22","author":"Leman","year":"2005","journal-title":"Emerg Med J"},{"issue":"7483","key":"10.1016\/j.cmi.2017.02.036_bib12","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1136\/bmj.38309.447975.EB","article-title":"Randomised controlled trial of intravenous antibiotic treatment for cellulitis at home compared with hospital","volume":"330","author":"Corwin","year":"2005","journal-title":"BMJ"},{"key":"10.1016\/j.cmi.2017.02.036_bib13","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1097\/00007611-199106000-00030","article-title":"Necrotizing fasciitis and nonsteroidal anti-inflammatory drugs","volume":"84","author":"Smith","year":"1991","journal-title":"South Med J"},{"key":"10.1016\/j.cmi.2017.02.036_bib14","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1097\/00006454-199908000-00014","article-title":"NSAIDS and necrotizing fasciitis","volume":"18","author":"Zerr","year":"1999","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.cmi.2017.02.036_bib15","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/S0035-1040(06)75839-1","article-title":"Necrotizing cellulitis complicating varicella in two children given nonsteroidal anti-inflammatory drugs","volume":"92","author":"Louis","year":"2006","journal-title":"Rev Chir Orthop Reparatrice Appar Mot"},{"key":"10.1016\/j.cmi.2017.02.036_bib16","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1111\/j.1365-2613.2008.00594.x","article-title":"Does diclofenac increase the risk of cervical necrotizing fasciitis in a rat model?","volume":"90","author":"Eter","year":"2009","journal-title":"Int J Exp Pathol"},{"key":"10.1016\/j.cmi.2017.02.036_bib17","doi-asserted-by":"crossref","first-page":"369","DOI":"10.2165\/00002018-199717060-00003","article-title":"Nonsteroidal anti-inflammatory drugs and necrotising fasciitis. An update","volume":"17","author":"Holder","year":"1997","journal-title":"Drug Saf"},{"issue":"1124","key":"10.1016\/j.cmi.2017.02.036_bib18","first-page":"3","article-title":"Necrotizing fasciitis and non steroidal anti-inflammatory drugs: a case series and review of the literature","volume":"114","author":"Forbes","year":"2001","journal-title":"N\u00a0Z Med J"},{"key":"10.1016\/j.cmi.2017.02.036_bib19","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1097\/01.md.0000085060.63483.bb","article-title":"Assessing the relationship between the use of nonsteroidal antiinflammatory drugs and necrotizing fasciitis caused by group A streptococcus","volume":"82","author":"Aronoff","year":"2003","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.cmi.2017.02.036_bib20","doi-asserted-by":"crossref","first-page":"2218","DOI":"10.1093\/ajhp\/53.18.2218","article-title":"No basis for associating nonprescription ibuprofen and similar agents with necrotizing fasciitis","volume":"53","author":"Melis","year":"1996","journal-title":"Am J Health Syst Pharm"}],"container-title":["Clinical Microbiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1198743X17301404?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1198743X17301404?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,19]],"date-time":"2019-09-19T10:30:26Z","timestamp":1568889026000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1198743X17301404"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4]]},"references-count":20,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,4]]}},"alternative-id":["S1198743X17301404"],"URL":"https:\/\/doi.org\/10.1016\/j.cmi.2017.02.036","relation":{},"ISSN":["1198-743X"],"issn-type":[{"value":"1198-743X","type":"print"}],"subject":[],"published":{"date-parts":[[2017,4]]}}}