{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T11:08:15Z","timestamp":1790507295578,"version":"4.1.0"},"reference-count":17,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"name":"Health Research Fund (FIS) of the Carlos III Health Institute (ISCIII)","award":["CP13\/00268"],"award-info":[{"award-number":["CP13\/00268"]}]},{"name":"Consejer\u00eda de Educaci\u00f3n, Juventud y Deporte de la Comunidad de Madrid y Fondo Social Europeo","award":["PEJ15\/BIO\/AI-0406"],"award-info":[{"award-number":["PEJ15\/BIO\/AI-0406"]}]},{"DOI":"10.13039\/501100004587","name":"ISCIII","doi-asserted-by":"publisher","award":["PI14\/01933"],"award-info":[{"award-number":["PI14\/01933"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund (FEDER)","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Microbiology and Infection"],"published-print":{"date-parts":[[2018,6]]},"DOI":"10.1016\/j.cmi.2017.10.018","type":"journal-article","created":{"date-parts":[[2017,10,27]],"date-time":"2017-10-27T16:05:26Z","timestamp":1509120326000},"page":"659.e1-659.e3","source":"Crossref","is-referenced-by-count":21,"title":["Biofilm production is not associated with poor clinical outcome in 485 patients with Staphylococcus aureus bacteraemia"],"prefix":"10.1016","volume":"24","author":[{"given":"M.","family":"Guembe","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Alonso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Lucio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.J.","family":"P\u00e9rez-Granda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Cruces","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"S\u00e1nchez-Carrillo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Fern\u00e1ndez-Cruz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Bouza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cmi.2017.10.018_bib1","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1128\/CMR.00134-14","article-title":"Staphylococcus aureus infections: epidemiology, pathophysiology, clinical manifestations, and management","volume":"28","author":"Tong","year":"2015","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.cmi.2017.10.018_bib2","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.ccc.2013.03.008","article-title":"Staphylococcus aureus bacteremia, risk factors, complications, and management","volume":"29","author":"Keynan","year":"2013","journal-title":"Crit Care Clin"},{"key":"10.1016\/j.cmi.2017.10.018_bib3","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1128\/CMR.05022-11","article-title":"Predictors of mortality in Staphylococcus aureus bacteremia","volume":"25","author":"van Hal","year":"2012","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.cmi.2017.10.018_bib4","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1007\/978-1-4939-2854-5_5","article-title":"A\u00a0microplate-based system as in\u00a0vitro model of biofilm growth and quantification","volume":"1333","author":"Vandecandelaere","year":"2016","journal-title":"Methods Mol Biol"},{"key":"10.1016\/j.cmi.2017.10.018_bib5","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.mimet.2010.08.018","article-title":"In\u00a0vitro and in\u00a0vivo model systems to study microbial biofilm formation","volume":"83","author":"Coenye","year":"2010","journal-title":"J\u00a0Microbiol Methods"},{"key":"10.1016\/j.cmi.2017.10.018_bib6","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.mimet.2016.10.011","article-title":"Does biomass production correlate with metabolic activity in Staphylococcus aureus?","volume":"131","author":"Alonso","year":"2016","journal-title":"J Microbiol Methods"},{"key":"10.1016\/j.cmi.2017.10.018_bib7","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.mimet.2007.11.010","article-title":"Comparison of multiple methods for quantification of microbial biofilms grown in microtiter plates","volume":"72","author":"Peeters","year":"2008","journal-title":"J\u00a0Microbiol Methods"},{"key":"10.1016\/j.cmi.2017.10.018_bib8","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.diagmicrobio.2014.07.003","article-title":"Risk factors for mortality in patients with bloodstream infections caused by carbapenem-resistant Pseudomonas aeruginosa: clinical impact of bacterial virulence and strains on outcome","volume":"80","author":"Jeong","year":"2014","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.cmi.2017.10.018_bib9","doi-asserted-by":"crossref","first-page":"1468","DOI":"10.1128\/JCM.44.4.1468-1474.2006","article-title":"Relationship of phylogenetic background, biofilm production, and time to detection of growth in blood culture vials with clinical variables and prognosis associated with Escherichia coli bacteremia","volume":"44","author":"Martinez","year":"2006","journal-title":"J\u00a0Clin Microbiol"},{"issue":"2","key":"10.1016\/j.cmi.2017.10.018_bib10","doi-asserted-by":"crossref","first-page":"345","DOI":"10.3904\/kjim.2015.287","article-title":"Association of biofilm production with colonization among clinical isolates of Acinetobacter baumannii","volume":"32","author":"Ryu","year":"2017","journal-title":"Korean J Intern Med"},{"key":"10.1016\/j.cmi.2017.10.018_bib11","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1097\/01.inf.0000176735.20008.cd","article-title":"Coagulase-negative staphylococcal sepsis in neonates. Association between antibiotic resistance, biofilm formation and the host inflammatory response","volume":"24","author":"Klingenberg","year":"2005","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.cmi.2017.10.018_bib12","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.cmi.2015.09.018","article-title":"Biofilm formation is a risk factor for mortality in patients with Candida albicans bloodstream infection\u2014Scotland, 2012\u20132013","volume":"22","author":"Rajendran","year":"2016","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.cmi.2017.10.018_bib13","doi-asserted-by":"crossref","first-page":"1843","DOI":"10.1128\/JCM.00131-07","article-title":"Biofilm production by Candida species and inadequate antifungal therapy as predictors of mortality for patients with candidemia","volume":"45","author":"Tumbarello","year":"2007","journal-title":"J\u00a0Clin Microbiol"},{"key":"10.1016\/j.cmi.2017.10.018_bib14","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0033705","article-title":"Risk factors and outcomes of candidemia caused by biofilm-forming isolates in a tertiary care hospital","volume":"7","author":"Tumbarello","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.cmi.2017.10.018_bib15","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1099\/jmm.0.000207","article-title":"In\u00a0vitro biofilm production of Candida bloodstream isolates: any association with clinical characteristics?","volume":"65","author":"Pongracz","year":"2016","journal-title":"J\u00a0Med Microbiol"},{"key":"10.1016\/j.cmi.2017.10.018_bib16","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1186\/s12879-015-0972-2","article-title":"Clinical infectious outcomes associated with biofilm-related bacterial infections: a retrospective chart review","volume":"15","author":"Barsoumian","year":"2015","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.cmi.2017.10.018_bib17","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1128\/AAC.02073-12","article-title":"Reduced vancomycin susceptibility in an in\u00a0vitro catheter-related biofilm model correlates with poor therapeutic outcomes in experimental endocarditis due to methicillin-resistant Staphylococcus aureus","volume":"57","author":"Abdelhady","year":"2014","journal-title":"Antimicrob Agents Chemother"}],"container-title":["Clinical Microbiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1198743X17305803?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1198743X17305803?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,23]],"date-time":"2019-09-23T23:45:41Z","timestamp":1569282341000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1198743X17305803"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6]]},"references-count":17,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2018,6]]}},"alternative-id":["S1198743X17305803"],"URL":"https:\/\/doi.org\/10.1016\/j.cmi.2017.10.018","relation":{},"ISSN":["1198-743X"],"issn-type":[{"value":"1198-743X","type":"print"}],"subject":[],"published":{"date-parts":[[2018,6]]}}}