{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T15:51:51Z","timestamp":1781279511458,"version":"3.54.1"},"reference-count":16,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2018,3,13]],"date-time":"2018-03-13T00:00:00Z","timestamp":1520899200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Institute for Health Research Health Protection Research Unit (NIHR HPRU)"},{"name":"Public Health England (PHE)"},{"name":"Public Health England and the Wellcome Trust","award":["098051"],"award-info":[{"award-number":["098051"]}]}],"content-domain":{"domain":["clinicalmicrobiologyandinfection.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Microbiology and Infection"],"published-print":{"date-parts":[[2018,9]]},"DOI":"10.1016\/j.cmi.2018.03.004","type":"journal-article","created":{"date-parts":[[2018,3,18]],"date-time":"2018-03-18T13:17:40Z","timestamp":1521379060000},"page":"1020.e1-1020.e4","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Low genomic diversity of Legionella pneumophila within clinical specimens"],"prefix":"10.1016","volume":"24","author":[{"given":"S.","family":"David","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Mentasti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Parkhill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.J.","family":"Chalker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cmi.2018.03.004_bib1","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1136\/jcp.33.12.1179","article-title":"Preliminary report on the pathogenicity of Legionella pneumophila for freshwater and soil amoebae","volume":"33","author":"Rowbotham","year":"1980","journal-title":"J\u00a0Clin Pathol"},{"key":"10.1016\/j.cmi.2018.03.004_bib2","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1001\/archinte.1986.00360200183030","article-title":"Mode of transmission of Legionella pneumophila\u2014a critical review","volume":"146","author":"Muder","year":"1986","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.cmi.2018.03.004_bib3","doi-asserted-by":"crossref","first-page":"2047","DOI":"10.1128\/JCM.43.5.2047-2052.2005","article-title":"Consensus sequence-based scheme for epidemiological typing of clinical and environmental isolates of Legionella pneumophila","volume":"43","author":"Gaia","year":"2005","journal-title":"J\u00a0Clin Microbiol"},{"key":"10.1016\/j.cmi.2018.03.004_bib4","doi-asserted-by":"crossref","first-page":"1965","DOI":"10.1128\/JCM.00261-07","article-title":"Addition of neuA, the gene encoding N-acylneuraminate cytidylyl transferase, increases the discriminatory ability of the consensus sequence-based scheme for typing Legionella pneumophila serogroup 1 strains","volume":"45","author":"Ratzow","year":"2007","journal-title":"J\u00a0Clin Microbiol"},{"key":"10.1016\/j.cmi.2018.03.004_bib5","doi-asserted-by":"crossref","first-page":"2017","DOI":"10.1007\/s10096-011-1535-0","article-title":"Application of Legionella pneumophila-specific quantitative real-time PCR combined with direct amplification and sequence-based typing in the diagnosis and epidemiological investigation of Legionnaires' disease","volume":"31","author":"Mentasti","year":"2012","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.cmi.2018.03.004_bib6","doi-asserted-by":"crossref","first-page":"2135","DOI":"10.1128\/JCM.00432-16","article-title":"Evaluation of an optimal epidemiological typing scheme for Legionella pneumophila with whole-genome sequence data using validation guidelines","volume":"54","author":"David","year":"2016","journal-title":"J\u00a0Clin Microbiol"},{"key":"10.1016\/j.cmi.2018.03.004_bib7","doi-asserted-by":"crossref","first-page":"118","DOI":"10.21105\/joss.00118","article-title":"Multilocus sequence typing by blast from de novo assemblies against PubMLST","volume":"1","author":"Page","year":"2016","journal-title":"JOSS"},{"key":"10.1016\/j.cmi.2018.03.004_bib8","doi-asserted-by":"crossref","first-page":"2068","DOI":"10.1093\/bioinformatics\/btu153","article-title":"Prokka. Rapid prokaryotic genome annotation","volume":"30","author":"Seemann","year":"2014","journal-title":"Bioinformatics"},{"key":"10.1016\/j.cmi.2018.03.004_bib9","doi-asserted-by":"crossref","first-page":"1754","DOI":"10.1093\/bioinformatics\/btp324","article-title":"Fast and accurate short read alignment with Burrows\u2013Wheeler transform","volume":"25","author":"Li","year":"2009","journal-title":"Bioinformatics"},{"key":"10.1016\/j.cmi.2018.03.004_bib10","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1038\/ng1447","article-title":"Evidence in the Legionella pneumophila genome for exploitation of host cell functions and high genome plasticity","volume":"36","author":"Cazalet","year":"2004","journal-title":"Nat Genet"},{"key":"10.1016\/j.cmi.2018.03.004_bib11","doi-asserted-by":"crossref","first-page":"2078","DOI":"10.1093\/bioinformatics\/btp352","article-title":"The sequence alignment\/map format and SAMtools","volume":"25","author":"Li","year":"2009","journal-title":"Bioinformatics"},{"key":"10.1016\/j.cmi.2018.03.004_bib12","doi-asserted-by":"crossref","first-page":"3691","DOI":"10.1093\/bioinformatics\/btv421","article-title":"Roary: rapid large-scale prokaryote pan genome analysis","volume":"31","author":"Page","year":"2015","journal-title":"Bioinformatics"},{"key":"10.1016\/j.cmi.2018.03.004_bib13","doi-asserted-by":"crossref","first-page":"R12","DOI":"10.1186\/gb-2004-5-2-r12","article-title":"Versatile and open software for comparing large genomes","volume":"5","author":"Kurtz","year":"2004","journal-title":"Genome Biol"},{"key":"10.1016\/j.cmi.2018.03.004_bib14","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1093\/cid\/civ870","article-title":"Hospital-wide eradication of a nosocomial Legionella pneumophila serogroup 1 outbreak","volume":"62","author":"Bartley","year":"2016","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.cmi.2018.03.004_bib15","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.ijmm.2013.11.002","article-title":"Mixed infection by Legionella pneumophila in outbreak patients","volume":"304","author":"Coscoll\u00e1","year":"2014","journal-title":"Int J Med Microbiol"},{"key":"10.1016\/j.cmi.2018.03.004_bib16","first-page":"504","article-title":"Gene flow in environmental Legionella pneumophila leads to genetic and pathogenic heterogeneity within a Legionnaires' disease outbreak","volume":"15","author":"McAdam","year":"2014","journal-title":"Genome Biol"}],"container-title":["Clinical Microbiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1198743X18302106?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1198743X18302106?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T07:20:20Z","timestamp":1761117620000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1198743X18302106"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9]]},"references-count":16,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2018,9]]}},"alternative-id":["S1198743X18302106"],"URL":"https:\/\/doi.org\/10.1016\/j.cmi.2018.03.004","relation":{},"ISSN":["1198-743X"],"issn-type":[{"value":"1198-743X","type":"print"}],"subject":[],"published":{"date-parts":[[2018,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Low genomic diversity of Legionella pneumophila within clinical specimens","name":"articletitle","label":"Article Title"},{"value":"Clinical Microbiology and Infection","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cmi.2018.03.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 The Author(s). Published by Elsevier Ltd on behalf of European Society of Clinical Microbiology and Infectious Diseases.","name":"copyright","label":"Copyright"}]}}