{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T23:13:08Z","timestamp":1761174788723,"version":"build-2065373602"},"reference-count":60,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"vor","delay-in-days":366,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalmicrobiologyandinfection.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Microbiology and Infection"],"published-print":{"date-parts":[[2019,4]]},"DOI":"10.1016\/j.cmi.2018.12.022","type":"journal-article","created":{"date-parts":[[2019,1,11]],"date-time":"2019-01-11T19:04:08Z","timestamp":1547233448000},"page":"422-430","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":25,"title":["High-throughput sequencing for the aetiologic identification of viral encephalitis, meningoencephalitis, and meningitis. A narrative review and clinical appraisal"],"prefix":"10.1016","volume":"25","author":[{"given":"M.-C.","family":"Zanella","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Lenggenhager","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Schrenzel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Cordey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Kaiser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.cmi.2018.12.022_bib1","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1086\/509330","article-title":"Beyond viruses: clinical profiles and etiologies associated with encephalitis","volume":"43","author":"Glaser","year":"2006","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.cmi.2018.12.022_bib2","doi-asserted-by":"crossref","first-page":"1838","DOI":"10.1086\/648419","article-title":"Infectious encephalitis in France in 2007: a national prospective study","volume":"49","author":"Mailles","year":"2009","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.cmi.2018.12.022_bib3","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1016\/S1473-3099(10)70222-X","article-title":"Causes of encephalitis and differences in their clinical presentations in England: a multicentre, population-based prospective study","volume":"10","author":"Granerod","year":"2010","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.cmi.2018.12.022_bib4","first-page":"1255","article-title":"Acute bacterial and viral meningitis","volume":"18","author":"Bartt","year":"2012","journal-title":"Continuum (Minneap Minn)"},{"key":"10.1016\/j.cmi.2018.12.022_bib5","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1002\/jmv.23470","article-title":"Viral infections of the central nervous system in Spain: a prospective study","volume":"85","author":"de Ory","year":"2013","journal-title":"J\u00a0Med Virol"},{"key":"10.1016\/j.cmi.2018.12.022_bib6","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1136\/bmj.39409.673657.AE","article-title":"Viral meningitis","volume":"336","author":"Logan","year":"2008","journal-title":"BMJ"},{"key":"10.1016\/j.cmi.2018.12.022_bib7","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1212\/01.wnl.0000191407.81333.00","article-title":"Etiology of aseptic meningitis and encephalitis in an adult population","volume":"66","author":"Kupila","year":"2006","journal-title":"Neurology"},{"key":"10.1016\/j.cmi.2018.12.022_bib8","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.medmal.2017.01.005","article-title":"Guidelines on the management of infectious encephalitis in adults","volume":"47","author":"Stahl","year":"2017","journal-title":"Med Mal Infect"},{"key":"10.1016\/j.cmi.2018.12.022_bib9","doi-asserted-by":"crossref","first-page":"750","DOI":"10.4103\/ijmr.IJMR_747_14","article-title":"Genetic characterization of human herpesvirus type 1: full-length genome sequence of strain obtained from an encephalitis case from India","volume":"144","author":"Bondre","year":"2016","journal-title":"Indian J Med Res"},{"key":"10.1016\/j.cmi.2018.12.022_bib10","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1007\/s00430-016-0464-z","article-title":"Analysis of an echovirus 18 outbreak in Thuringia, Germany: insights into the molecular epidemiology and evolution of several enterovirus species B members","volume":"205","author":"Krumbholz","year":"2016","journal-title":"Med Microbiol Immunol"},{"key":"10.1016\/j.cmi.2018.12.022_bib11","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/S0140-6736(16)30386-5","article-title":"Late Ebola virus relapse causing meningoencephalitis: a case report","volume":"388","author":"Jacobs","year":"2016","journal-title":"Lancet"},{"key":"10.1016\/j.cmi.2018.12.022_bib12","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1089\/vbz.2014.1668","article-title":"Toscana virus genome stability: data from a meningoencephalitis case in Mantua, Italy","volume":"14","author":"Magurano","year":"2014","journal-title":"Vector Borne Zoonotic Dis"},{"key":"10.1016\/j.cmi.2018.12.022_bib13","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1002\/ana.24016","article-title":"Phylogenetic and epidemiologic evidence of multiyear incubation in human rabies","volume":"75","author":"Boland","year":"2014","journal-title":"Ann Neurol"},{"key":"10.1016\/j.cmi.2018.12.022_bib14","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1093\/infdis\/jis479","article-title":"Metagenomic and metabolomic characterization of rabies encephalitis: new insights into the treatment of an ancient disease","volume":"207","author":"Reinke","year":"2013","journal-title":"J\u00a0Infect Dis"},{"key":"10.1016\/j.cmi.2018.12.022_bib15","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1089\/vbz.2013.1316","article-title":"Isolation of Toscana virus from the cerebrospinal fluid of a man with meningitis in Marseille, France, 2010","volume":"13","author":"Nougairede","year":"2013","journal-title":"Vector Borne Zoonotic Dis"},{"key":"10.1016\/j.cmi.2018.12.022_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.cmi.2014.11.010","article-title":"Toscana virus meningitis case in Switzerland: an example of the ezVIR bioinformatics pipeline utility for the identification of emerging viruses","volume":"21","author":"Cordey","year":"2015","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.cmi.2018.12.022_bib17","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1016\/S1473-3099(15)70093-9","article-title":"A\u00a0novel outbreak enterovirus D68 strain associated with acute flaccid myelitis cases in the USA (2012-14): a retrospective cohort study","volume":"15","author":"Greninger","year":"2015","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.cmi.2018.12.022_bib18","doi-asserted-by":"crossref","first-page":"20974","DOI":"10.2807\/1560-7917.ES2014.19.48.20974","article-title":"Afebrile meningoencephalitis with transient central facial paralysis due to Toscana virus infection, southeastern France, 2014 [corrected]","volume":"19","author":"Marlinge","year":"2014","journal-title":"Euro Surveill"},{"key":"10.1016\/j.cmi.2018.12.022_bib19","doi-asserted-by":"crossref","first-page":"e104","DOI":"10.1038\/emi.2016.101","article-title":"Molecular epidemiology of human enterovirus 71 at the origin of an epidemic of fatal hand, foot and mouth disease cases in Cambodia","volume":"5","author":"Duong","year":"2016","journal-title":"Emerg Microbes Infect"},{"key":"10.1016\/j.cmi.2018.12.022_bib20","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1056\/NEJMoa1415627","article-title":"A\u00a0variegated Squirrel Bornavirus associated with fatal human encephalitis","volume":"373","author":"Hoffmann","year":"2015","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.cmi.2018.12.022_bib21","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0006198","article-title":"Isolation and complete genome analysis of neurotropic dengue virus serotype 3 from the cerebrospinal fluid of an encephalitis patient","volume":"12","author":"Dhenni","year":"2018","journal-title":"PLoS Negl Trop Dis"},{"key":"10.1016\/j.cmi.2018.12.022_bib22","doi-asserted-by":"crossref","first-page":"846","DOI":"10.3201\/eid2205.151807","article-title":"Astrovirus MLB2, a new gastroenteric virus associated with meningitis and disseminated infection","volume":"22","author":"Cordey","year":"2016","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.cmi.2018.12.022_bib23","doi-asserted-by":"crossref","first-page":"e53","DOI":"10.1093\/jpids\/piv040","article-title":"Next-generation sequencing for diagnosis and tailored therapy: a case report of astrovirus-associated progressive encephalitis","volume":"4","author":"Fr\u00e9mond","year":"2015","journal-title":"J\u00a0Pediatr Infect Dis Soc"},{"key":"10.1016\/j.cmi.2018.12.022_bib24","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.jcv.2016.03.010","article-title":"Acute encephalopathy in an immunocompromised boy with astrovirus-MLB1 infection detected by next generation sequencing","volume":"78","author":"Sato","year":"2016","journal-title":"J\u00a0Clin Virol"},{"key":"10.1016\/j.cmi.2018.12.022_bib25","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1056\/NEJMc1509458","article-title":"Human coronavirus OC43 associated with fatal encephalitis","volume":"375","author":"Morfopoulou","year":"2016","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.cmi.2018.12.022_bib26","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1056\/NEJMoa073785","article-title":"A\u00a0new arenavirus in a cluster of fatal transplant-associated diseases","volume":"358","author":"Palacios","year":"2008","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.cmi.2018.12.022_bib27","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.virol.2015.03.011","article-title":"Small circular single stranded DNA viral genomes in unexplained cases of human encephalitis, diarrhea, and in untreated sewage","volume":"482","author":"Phan","year":"2015","journal-title":"Virology"},{"key":"10.1016\/j.cmi.2018.12.022_bib28","article-title":"Identification of a new cyclovirus in cerebrospinal fluid of patients with acute central nervous system infections","volume":"4","author":"Tan le","year":"2013","journal-title":"MBio"},{"key":"10.1016\/j.cmi.2018.12.022_bib29","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1093\/infdis\/jix040","article-title":"A\u00a0cluster of fatal tick-borne encephalitis virus infection in organ transplant setting","volume":"215","author":"Lipowski","year":"2017","journal-title":"J\u00a0Infect Dis"},{"key":"10.1016\/j.cmi.2018.12.022_bib30","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1002\/ana.24982","article-title":"A\u00a0novel cause of chronic viral meningoencephalitis: Cache Valley virus","volume":"82","author":"Wilson","year":"2017","journal-title":"Ann Neurol"},{"key":"10.1016\/j.cmi.2018.12.022_bib31","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1093\/cid\/ciu940","article-title":"Astrovirus VA1\/HMO-C: an increasingly recognized neurotropic pathogen in immunocompromised patients","volume":"60","author":"Brown","year":"2015","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.cmi.2018.12.022_bib32","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1186\/s13073-015-0235-2","article-title":"Clinical metagenomic identification of Balamuthia mandrillaris encephalitis and assembly of the draft genome: the continuing case for reference genome sequencing","volume":"7","author":"Greninger","year":"2015","journal-title":"Genome Med"},{"key":"10.1016\/j.cmi.2018.12.022_bib33","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1093\/cid\/ciu912","article-title":"Diagnosis of neuroinvasive astrovirus infection in an immunocompromised adult with encephalitis by unbiased next-generation sequencing","volume":"60","author":"Naccache","year":"2015","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.cmi.2018.12.022_bib34","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0093993","article-title":"Deep sequencing to identify the causes of viral encephalitis","volume":"9","author":"Chan","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.cmi.2018.12.022_bib35","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jviromet.2015.09.010","article-title":"Next-generation sequencing (NGS) in the identification of encephalitis-causing viruses: unexpected detection of human herpesvirus 1 while searching for RNA pathogens","volume":"226","author":"Perlejewski","year":"2015","journal-title":"J\u00a0Virol Methods"},{"key":"10.1016\/j.cmi.2018.12.022_bib36","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1007\/s13365-015-0390-7","article-title":"Detection of virus in CSF from the cases with meningoencephalitis by next-generation sequencing","volume":"22","author":"Guan","year":"2016","journal-title":"J\u00a0Neurovirol"},{"key":"10.1016\/j.cmi.2018.12.022_bib37","doi-asserted-by":"crossref","first-page":"3231","DOI":"10.1007\/s00705-016-3002-9","article-title":"A\u00a0new densovirus in cerebrospinal fluid from a case of anti-NMDA-receptor encephalitis","volume":"161","author":"Phan","year":"2016","journal-title":"Arch Virol"},{"key":"10.1016\/j.cmi.2018.12.022_bib38","doi-asserted-by":"crossref","first-page":"1919","DOI":"10.1007\/s00277-016-2770-3","article-title":"Suspected encephalitis with Candida tropicalis and Fusarium detected by unbiased RNA sequencing","volume":"95","author":"Christopeit","year":"2016","journal-title":"Ann Hematol"},{"key":"10.1016\/j.cmi.2018.12.022_bib39","doi-asserted-by":"crossref","first-page":"e251","DOI":"10.1212\/NXI.0000000000000251","article-title":"Next-generation sequencing in neuropathologic diagnosis of infections of the nervous system","volume":"3","author":"Salzberg","year":"2016","journal-title":"Neurol Neuroimmunol Neuroinflamm"},{"key":"10.1016\/j.cmi.2018.12.022_bib40","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1111\/ajt.14058","article-title":"Acute West Nile virus meningoencephalitis diagnosed via metagenomic deep sequencing of cerebrospinal fluid in a renal transplant patient","volume":"17","author":"Wilson","year":"2017","journal-title":"Am J Transplant"},{"key":"10.1016\/j.cmi.2018.12.022_bib41","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1007\/s00401-016-1629-y","article-title":"Deep sequencing reveals persistence of cell-associated mumps vaccine virus in chronic encephalitis","volume":"133","author":"Morfopoulou","year":"2017","journal-title":"Acta Neuropathol"},{"key":"10.1016\/j.cmi.2018.12.022_bib42","doi-asserted-by":"crossref","first-page":"1964","DOI":"10.3201\/eid2310.161986","article-title":"Diagnosis of fatal human case of St. Louis encephalitis virus infection by metagenomic sequencing, California, 2016","volume":"23","author":"Chiu","year":"2017","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.cmi.2018.12.022_bib43","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1111\/tid.12607","article-title":"An emerging opportunistic infection: fatal astrovirus (VA1\/HMO-C) encephalitis in a pediatric stem cell transplant recipient","volume":"18","author":"Lum","year":"2016","journal-title":"Transpl Infect Dis"},{"key":"10.1016\/j.cmi.2018.12.022_bib44","doi-asserted-by":"crossref","first-page":"2408","DOI":"10.1056\/NEJMoa1401268","article-title":"Actionable diagnosis of neuroleptospirosis by next-generation sequencing","volume":"370","author":"Wilson","year":"2014","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.cmi.2018.12.022_bib45","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1002\/ana.24499","article-title":"Diagnosing Balamuthia mandrillaris encephalitis with metagenomic deep sequencing","volume":"78","author":"Wilson","year":"2015","journal-title":"Ann Neurol"},{"key":"10.1016\/j.cmi.2018.12.022_bib46","first-page":"1484","article-title":"Human parvovirus 4 as potential cause of encephalitis in children, India","volume":"17","author":"Benjamin","year":"2011","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.cmi.2018.12.022_bib47","doi-asserted-by":"crossref","first-page":"918","DOI":"10.3201\/eid1606.091536","article-title":"Astrovirus encephalitis in boy with X-linked agammaglobulinemia","volume":"16","author":"Quan","year":"2010","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.cmi.2018.12.022_bib48","doi-asserted-by":"crossref","first-page":"33452","DOI":"10.1038\/srep33452","article-title":"Identification of viruses in cases of pediatric acute encephalitis and encephalopathy using next-generation sequencing","volume":"6","author":"Kawada","year":"2016","journal-title":"Sci Rep"},{"key":"10.1016\/j.cmi.2018.12.022_bib49","doi-asserted-by":"crossref","first-page":"1861","DOI":"10.1002\/jmv.24839","article-title":"Detection of Toscana virus from an adult traveler returning to Australia with encephalitis","volume":"89","author":"Arden","year":"2017","journal-title":"J\u00a0Med Virol"},{"key":"10.1016\/j.cmi.2018.12.022_bib50","first-page":"393","article-title":"Neurobrucellosis: unexpected answer from metagenomic next-generation sequencing","volume":"6","author":"Mongkolrattanothai","year":"2017","journal-title":"J\u00a0Pediatr Infect Dis Soc"},{"key":"10.1016\/j.cmi.2018.12.022_bib51","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1007\/s00705-015-2363-9","article-title":"Human anelloviruses: an update of molecular, epidemiological and clinical aspects","volume":"160","author":"Spandole","year":"2015","journal-title":"Arch Virol"},{"key":"10.1016\/j.cmi.2018.12.022_bib52","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1002\/rmv.668","article-title":"Human anelloviruses and the central nervous system","volume":"20","author":"Maggi","year":"2010","journal-title":"Rev Med Virol"},{"key":"10.1016\/j.cmi.2018.12.022_bib53","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1002\/jmv.2051","article-title":"Low prevalence of TT virus in the cerebrospinal fluid of viremic patients with central nervous system disorders","volume":"65","author":"Maggi","year":"2001","journal-title":"J\u00a0Med Virol"},{"key":"10.1016\/j.cmi.2018.12.022_bib54","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1046\/j.1365-2893.2003.00417.x","article-title":"TT virus has a ubiquitous diffusion in human body tissues: analyses of paired serum and tissue samples","volume":"10","author":"Pollicino","year":"2003","journal-title":"J\u00a0Viral Hepat"},{"key":"10.1016\/j.cmi.2018.12.022_bib55","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0031886","article-title":"Deep sequencing for the detection of virus-like sequences in the brains of patients with multiple sclerosis: detection of GBV-C in human brain","volume":"7","author":"Kriesel","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.cmi.2018.12.022_bib56","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1017\/S0950268815001326","article-title":"Detection of GB virus C genomic sequence in the cerebrospinal fluid of a HIV-infected patient in China: a case report and literature review","volume":"144","author":"Liu","year":"2016","journal-title":"Epidemiol Infect"},{"key":"10.1016\/j.cmi.2018.12.022_bib57","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.jcv.2017.04.007","article-title":"Human pegivirus-1 in the CSF of patients with HIV-associated neurocognitive disorder (HAND) may be derived from blood in highly viraemic patients","volume":"91","author":"Hardie","year":"2017","journal-title":"J\u00a0Clin Virol"},{"key":"10.1016\/j.cmi.2018.12.022_bib58","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1086\/589747","article-title":"The management of encephalitis: clinical practice guidelines by the Infectious Diseases Society of America","volume":"47","author":"Tunkel","year":"2008","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.cmi.2018.12.022_bib59","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1038\/nrmicro2949","article-title":"The changing face of pathogen discovery and surveillance","volume":"11","author":"Lipkin","year":"2013","journal-title":"Nat Rev Microbiol"},{"key":"10.1016\/j.cmi.2018.12.022_bib60","doi-asserted-by":"crossref","first-page":"776","DOI":"10.5858\/arpa.2016-0539-RA","article-title":"Validation of metagenomic next-generation sequencing tests for universal pathogen detection","volume":"141","author":"Schlaberg","year":"2017","journal-title":"Arch Pathol Lab Med"}],"container-title":["Clinical Microbiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1198743X18308127?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1198743X18308127?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T07:21:25Z","timestamp":1761117685000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1198743X18308127"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4]]},"references-count":60,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,4]]}},"alternative-id":["S1198743X18308127"],"URL":"https:\/\/doi.org\/10.1016\/j.cmi.2018.12.022","relation":{},"ISSN":["1198-743X"],"issn-type":[{"type":"print","value":"1198-743X"}],"subject":[],"published":{"date-parts":[[2019,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"High-throughput sequencing for the aetiologic identification of viral encephalitis, meningoencephalitis, and meningitis. A narrative review and clinical appraisal","name":"articletitle","label":"Article Title"},{"value":"Clinical Microbiology and Infection","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cmi.2018.12.022","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}