{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T17:05:59Z","timestamp":1778605559601,"version":"3.51.4"},"reference-count":24,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100013076","name":"National Major Science and Technology Projects of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013076","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalmicrobiologyandinfection.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Microbiology and Infection"],"published-print":{"date-parts":[[2020,11]]},"DOI":"10.1016\/j.cmi.2020.02.009","type":"journal-article","created":{"date-parts":[[2020,2,13]],"date-time":"2020-02-13T02:34:57Z","timestamp":1581561297000},"page":"1555.e1-1555.e7","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"title":["Dynamic changes of interferon gamma release assay results with latent tuberculosis infection treatment"],"prefix":"10.1016","volume":"26","author":[{"given":"H.","family":"Xin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"X.","family":"Cao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Pan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"X.","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Guan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Shen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Z.","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"X.","family":"Guan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Yan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Feng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Q.","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Q.","family":"Jin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Gao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.cmi.2020.02.009_bib1","doi-asserted-by":"crossref","first-page":"2127","DOI":"10.1056\/NEJMra1405427","article-title":"Latent Mycobacterium tuberculosis infection","volume":"372","author":"Getahun","year":"2015","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.cmi.2020.02.009_bib3","first-page":"276","article-title":"Reversion of QuantiFERON-TB Gold In-Tube test in individuals with and without prophylactic treatment for latent tuberculosis infection: a systematic review and meta-analysis","volume":"77","author":"Zhang","year":"2018","journal-title":"J\u00a0Infect"},{"key":"10.1016\/j.cmi.2020.02.009_bib4","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1086\/499311","article-title":"Effect of treatment of latent tuberculosis infection on the T-cell response to Mycobacterium tuberculosis antigens","volume":"193","author":"Wilkinson","year":"2006","journal-title":"J\u00a0Infect Dis"},{"key":"10.1016\/j.cmi.2020.02.009_bib5","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/1745-6673-1-7","article-title":"Persistently elevated T-cell interferon-gamma responses after treatment for latent tuberculosis infection among health care workers in India: a preliminary report","volume":"1","author":"Pai","year":"2006","journal-title":"J\u00a0Occup Med Toxicol"},{"key":"10.1016\/j.cmi.2020.02.009_bib6","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1111\/j.1440-1843.2008.01244.x","article-title":"Interferon-gamma responses after isoniazid chemotherapy for latent tuberculosis","volume":"13","author":"Higuchi","year":"2008","journal-title":"Respirology"},{"key":"10.1016\/j.cmi.2020.02.009_bib7","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/j.tube.2015.07.002","article-title":"Interferon gamma release assays for monitoring the response to treatment for tuberculosis: a systematic review","volume":"95","author":"Clifford","year":"2015","journal-title":"Tuberculosis (Edinb)"},{"key":"10.1016\/j.cmi.2020.02.009_bib8","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1164\/rccm.201208-1352OC","article-title":"Interferon-\u03b3 ELISPOT as a biomarker of treatment efficacy in latent tuberculosis infection: a clinical trial","volume":"187","author":"Adetifa","year":"2013","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.cmi.2020.02.009_bib9","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1164\/rccm.200511-1783OC","article-title":"Dynamic antigen-specific T-cell responses after point-source exposure to Mycobacterium tuberculosis","volume":"174","author":"Ewer","year":"2006","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.cmi.2020.02.009_bib10","doi-asserted-by":"crossref","first-page":"1801470","DOI":"10.1183\/13993003.01470-2018","article-title":"Short-course regimens of rifapentine plus isoniazid to treat latent tuberculosis infection in older Chinese: a randomised controlled study","volume":"52","author":"Gao","year":"2018","journal-title":"Eur Respir J"},{"key":"10.1016\/j.cmi.2020.02.009_bib12","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1086\/381754","article-title":"Use of a T cell\u2013based assay for monitoring efficacy of antituberculosis therapy","volume":"38","author":"Carrara","year":"2004","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.cmi.2020.02.009_bib13","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1038\/nrmicro2236","article-title":"The spectrum of latent tuberculosis: rethinking the biology and intervention strategies","volume":"7","author":"Barry","year":"2009","journal-title":"Nat Rev Microbiol"},{"key":"10.1016\/j.cmi.2020.02.009_bib14","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.2217\/fmb.11.82","article-title":"Redefining latent tuberculosis","volume":"6","author":"Sridhar","year":"2011","journal-title":"Future Microbiol"},{"key":"10.1016\/j.cmi.2020.02.009_bib15","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.dsi.2014.12.005","article-title":"Serial QuantiFERON-TB Gold In-Tube testing for psoriatic patients receiving antitumor necrosis factor-alpha therapy","volume":"3","author":"Cheng","year":"2015","journal-title":"Dermatol Sin"},{"key":"10.1016\/j.cmi.2020.02.009_bib16","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1164\/rccm.200608-1109OC","article-title":"Latent tuberculosis infection treatment and T-cell responses to Mycobacterium tuberculosis\u2013specific antigens","volume":"175","author":"Chee","year":"2007","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.cmi.2020.02.009_bib17","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0008517","article-title":"Within-subject variability of interferon-gamma assay results for tuberculosis and boosting effect of tuberculin skin testing: a systematic review","volume":"4","author":"van Zyl-Smit","year":"2009","journal-title":"PLoS One"},{"key":"10.1016\/j.cmi.2020.02.009_bib18","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1128\/JCM.02803-15","article-title":"Interferon gamma release assays for latent tuberculosis: what are the sources of variability?","volume":"54","author":"Banaei","year":"2016","journal-title":"J\u00a0Clin Microbiol"},{"key":"10.1016\/j.cmi.2020.02.009_bib19","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1378\/chest.13-1232","article-title":"Effect of isoniazid therapy for latent TB infection on QuantiFERON-TB Gold In-Tube responses in adults with positive tuberculin skin test results in a high TB incidence area: a controlled study","volume":"145","author":"Johnson","year":"2014","journal-title":"Chest"},{"key":"10.1016\/j.cmi.2020.02.009_bib20","doi-asserted-by":"crossref","first-page":"15626","DOI":"10.1038\/s41598-018-33825-w","article-title":"Effect of therapy on QuantiFERON-Plus response in patients with active and latent tuberculosis infection","volume":"8","author":"Petruccioli","year":"2018","journal-title":"Sci Rep"},{"key":"10.1016\/j.cmi.2020.02.009_bib21","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1186\/1471-2334-11-245","article-title":"Specificity of a whole blood IGRA in German nursing students","volume":"11","author":"Schablon","year":"2011","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.cmi.2020.02.009_bib22","doi-asserted-by":"crossref","first-page":"163","DOI":"10.5588\/ijtld.11.0364","article-title":"Serial testing of Malaysian health care workers with QuantiFERON\u00ae-TB Gold In-Tube","volume":"16","author":"Rafiza","year":"2012","journal-title":"Int J Tuberc Lung Dis"},{"key":"10.1016\/j.cmi.2020.02.009_bib23","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1164\/rccm.201704-0817OC","article-title":"Optimization and interpretation of serial QuantiFERON testing to measure acquisition of Mycobacterium tuberculosis infection","volume":"196","author":"Nemes","year":"2017","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.cmi.2020.02.009_bib24","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1136\/thoraxjnl-2017-211147","article-title":"Stratification by interferon-\u03b3 release assay level predicts risk of incident TB","volume":"73","author":"Winje","year":"2018","journal-title":"Thorax"},{"key":"10.1016\/j.cmi.2020.02.009_bib25","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/S1473-3099(14)71085-0","article-title":"Latent tuberculosis infection in rural China: baseline results of a population-based, multicenter, prospective cohort study","volume":"15","author":"Gao","year":"2015","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.cmi.2020.02.009_bib26","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.tube.2018.03.002","article-title":"Seasonal variation in the performance of QuantiFERON-TB Gold In-Tube assays used for the diagnosis of tuberculosis infection","volume":"110","author":"Tebruegge","year":"2018","journal-title":"Tuberculosis (Edinb)"}],"container-title":["Clinical Microbiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1198743X20300884?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1198743X20300884?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T07:25:56Z","timestamp":1761117956000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1198743X20300884"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11]]},"references-count":24,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2020,11]]}},"alternative-id":["S1198743X20300884"],"URL":"https:\/\/doi.org\/10.1016\/j.cmi.2020.02.009","relation":{},"ISSN":["1198-743X"],"issn-type":[{"value":"1198-743X","type":"print"}],"subject":[],"published":{"date-parts":[[2020,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dynamic changes of interferon gamma release assay results with latent tuberculosis infection treatment","name":"articletitle","label":"Article Title"},{"value":"Clinical Microbiology and Infection","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cmi.2020.02.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}