{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T00:47:01Z","timestamp":1790470021147,"version":"4.1.0"},"reference-count":15,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,9,6]],"date-time":"2022-09-06T00:00:00Z","timestamp":1662422400000},"content-version":"vor","delay-in-days":370,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","award":["10-IAHU-03"],"award-info":[{"award-number":["10-IAHU-03"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010076","name":"Conseil R\u00e9gional Provence-Alpes-C\u00f4te d'Azur","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010076","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalmicrobiologyandinfection.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Microbiology and Infection"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1016\/j.cmi.2021.05.006","type":"journal-article","created":{"date-parts":[[2021,5,12]],"date-time":"2021-05-12T12:18:17Z","timestamp":1620821897000},"page":"1352.e1-1352.e5","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":31,"title":["Spreading of a new SARS-CoV-2 N501Y spike variant in a new lineage"],"prefix":"10.1016","volume":"27","author":[{"given":"Philippe","family":"Colson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony","family":"Levasseur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy","family":"Delerce","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucile","family":"Pinault","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Dudouet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Devaux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre-Edouard","family":"Fournier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard","family":"La Scola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Christophe","family":"Lagier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Didier","family":"Raoult","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cmi.2021.05.006_bib1","series-title":"Dramatic increase in the SARS-CoV-2 mutation rate and low mortality rate during the second epidemic in summer in Marseille","author":"Colson","year":"2020"},{"key":"10.1016\/j.cmi.2021.05.006_bib2","article-title":"Genome sequence analysis enabled deciphering the atypical evolution of COVID-19 in Marseille, France","author":"Fournier","year":"2021","journal-title":"medRxiv"},{"key":"10.1016\/j.cmi.2021.05.006_bib3","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.ijid.2021.03.068","article-title":"Emergence and outcomes of the SARS-CoV-2 \u2018Marseille-4\u2019 variant","volume":"106","author":"Fournier","year":"2021","journal-title":"Int J Infect Dis"},{"key":"10.1016\/j.cmi.2021.05.006_bib4","article-title":"Circulating SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity","author":"Garcia-Beltran","year":"2021","journal-title":"medRxiv"},{"key":"10.1016\/j.cmi.2021.05.006_bib5","doi-asserted-by":"crossref","first-page":"101980","DOI":"10.1016\/j.tmaid.2021.101980","article-title":"Introduction into the Marseille geographical area of a mild SARS-CoV-2 variant originating from sub-Saharan Africa","volume":"40","author":"Colson","year":"2021","journal-title":"Travel Med Infect Dis"},{"key":"10.1016\/j.cmi.2021.05.006_bib6","doi-asserted-by":"crossref","first-page":"4121","DOI":"10.1093\/bioinformatics\/bty407","article-title":"Nextstrain: real-time tracking of pathogen evolution","volume":"34","author":"Hadfield","year":"2018","journal-title":"Bioinformatics"},{"key":"10.1016\/j.cmi.2021.05.006_bib7","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/S0022-2836(05)80360-2","article-title":"Basic local alignment search tool","volume":"215","author":"Altschul","year":"1990","journal-title":"J\u00a0Mol Biol"},{"key":"10.1016\/j.cmi.2021.05.006_bib8","doi-asserted-by":"crossref","DOI":"10.2807\/1560-7917.ES.2017.22.13.30494","article-title":"GISAID: Global initiative on sharing all influenza data \u2013 from vision to reality","volume":"22","author":"Shu","year":"2017","journal-title":"Euro Surveill"},{"key":"10.1016\/j.cmi.2021.05.006_bib9","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1093\/molbev\/mst010","article-title":"MAFFT multiple sequence alignment software version 7: improvements in performance and usability","volume":"30","author":"Katoh","year":"2013","journal-title":"Mol Biol Evol"},{"key":"10.1016\/j.cmi.2021.05.006_bib10","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1093\/molbev\/msu300","article-title":"IQ-TREE: a fast and effective stochastic algorithm for estimating maximum-likelihood phylogenies","volume":"32","author":"Nguyen","year":"2015","journal-title":"Mol Biol Evol"},{"key":"10.1016\/j.cmi.2021.05.006_bib11","doi-asserted-by":"crossref","first-page":"W242","DOI":"10.1093\/nar\/gkw290","article-title":"Interactive tree of life (iTOL) v3: an online tool for the display and annotation of phylogenetic and other trees","volume":"44","author":"Letunic","year":"2016","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.cmi.2021.05.006_bib12","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1007\/s10096-020-03913-9","article-title":"Viral RNA load as determined by cell culture as a management tool for discharge of SARS-CoV-2 patients from infectious disease wards","volume":"39","author":"La Scola","year":"2020","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.cmi.2021.05.006_bib13","article-title":"L18F substrain of SARS-CoV-2 VOC-202012\/01 is rapidly spreading in England","author":"Grabowski","year":"2021","journal-title":"medRxiv"},{"key":"10.1016\/j.cmi.2021.05.006_bib14","doi-asserted-by":"crossref","DOI":"10.1038\/s41586-021-03291-y","article-title":"SARS-CoV-2 evolution during treatment of chronic infection","author":"Kemp","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.cmi.2021.05.006_bib15","article-title":"Rapid detection of inter-clade recombination in SARS-CoV-2 with Bolotie","author":"Varabyou","year":"2020","journal-title":"bioRxiv"}],"container-title":["Clinical Microbiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1198743X21002263?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1198743X21002263?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T13:23:53Z","timestamp":1778592233000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1198743X21002263"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":15,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["S1198743X21002263"],"URL":"https:\/\/doi.org\/10.1016\/j.cmi.2021.05.006","relation":{},"ISSN":["1198-743X"],"issn-type":[{"value":"1198-743X","type":"print"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Spreading of a new SARS-CoV-2 N501Y spike variant in a new lineage","name":"articletitle","label":"Article Title"},{"value":"Clinical Microbiology and Infection","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cmi.2021.05.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}