{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T02:29:38Z","timestamp":1781058578990,"version":"3.54.1"},"reference-count":14,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T00:00:00Z","timestamp":1692921600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalmicrobiologyandinfection.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Microbiology and Infection"],"published-print":{"date-parts":[[2023,12]]},"DOI":"10.1016\/j.cmi.2023.08.015","type":"journal-article","created":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T11:11:51Z","timestamp":1692616311000},"page":"1603.e1-1603.e4","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Anti-Treponema pallidum IgA response as a potential diagnostic marker of syphilis"],"prefix":"10.1016","volume":"29","author":[{"given":"Islay","family":"Rodr\u00edguez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angel A.","family":"Noda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philipp P.","family":"Bosshard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reto","family":"Lienhard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cmi.2023.08.015_bib1","volume":"3","author":"Peeling","year":"2017","journal-title":"Syphilis Nat Rev Dis Primers"},{"issue":"9","key":"10.1016\/j.cmi.2023.08.015_bib2","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1056\/NEJMra1901593","article-title":"The modern epidemic of syphilis","volume":"382","author":"Ghanem","year":"2020","journal-title":"N\u00a0Engl J Med"},{"issue":"1","key":"10.1016\/j.cmi.2023.08.015_bib3","first-page":"35","article-title":"Usefulness of IgM-specific enzyme immunoassays for serodiagnosis of syphilis: comparative evaluation of three different assays","volume":"67","author":"Bosshard","year":"2013","journal-title":"J\u00a0Infect"},{"key":"10.1016\/j.cmi.2023.08.015_bib4","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1002\/path.1877","article-title":"The function of immunoglobulin A in immunity","volume":"208","author":"Woof","year":"2006","journal-title":"J\u00a0Pathol"},{"issue":"4","key":"10.1016\/j.cmi.2023.08.015_bib5","doi-asserted-by":"crossref","first-page":"57","DOI":"10.3390\/antib8040057","article-title":"IgA: structure, function, and developability","volume":"8","author":"De Sousa Pereira","year":"2019","journal-title":"Antibodies"},{"issue":"3","key":"10.1016\/j.cmi.2023.08.015_bib6","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0003596","article-title":"Evaluation of the diagnostic accuracy of a new dengue IgA capture assay (Platelia Dengue IgA Capture, Bio-Rad) for dengue infection detection","volume":"9","author":"De Decker","year":"2015","journal-title":"PLos Negl Trop Dis"},{"issue":"4","key":"10.1016\/j.cmi.2023.08.015_bib7","doi-asserted-by":"crossref","first-page":"326","DOI":"10.4103\/0255-0857.71823","article-title":"Diagnosis and follow-up of genital chlamydial infection by direct methods and by detection of serum IgG, IgA and secretory IgA","volume":"28","author":"Fresse","year":"2010","journal-title":"Indian J Med Microbiol"},{"key":"10.1016\/j.cmi.2023.08.015_bib8","article-title":"Improving the coverage and accuracy of syphilis testing: the development of novel rapid, point-of-care test for confirmatory testing of active syphilis infection and its early evaluation in China and South Africa","volume":"24","author":"Pham","year":"2020","journal-title":"E\u00a0Clin Med"},{"issue":"6","key":"10.1016\/j.cmi.2023.08.015_bib9","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1128\/iai.1.6.555-558.1970","article-title":"Immunoglobulin class of natural human antibodies reactive with Treponema pallidum","volume":"1","author":"Julian","year":"1970","journal-title":"Infect Immunol"},{"issue":"1","key":"10.1016\/j.cmi.2023.08.015_bib10","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1128\/cdli.1.1.32-37.1994","article-title":"Laboratory diagnosis of congenital syphilis by immunoglobulin M (IgM) and IgA immunoblotting","volume":"1","author":"Schmitz","year":"1994","journal-title":"Clin Diag Lab Immunol"},{"key":"10.1016\/j.cmi.2023.08.015_bib11","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1128\/JCM.03444-14","article-title":"Performance of the 47-kilodalton membrane protein versus DNA polymerase I genes for detection of Treponema pallidum by PCR in ulcers","volume":"53","author":"Gayet-Ageron","year":"2015","journal-title":"J\u00a0Clin Microbiol"},{"issue":"11","key":"10.1016\/j.cmi.2023.08.015_bib12","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1177\/0956462419859764","article-title":"Accuracy of PCR and serological testing for the diagnosis of primary syphilis: both tests are necessary","volume":"30","author":"Noda","year":"2019","journal-title":"Int J STD AIDS"},{"issue":"12","key":"10.1016\/j.cmi.2023.08.015_bib13","doi-asserted-by":"crossref","first-page":"O1020","DOI":"10.1111\/1469-0691.12710","article-title":"A\u00a0multicenter prospective trial to asses a new real-time polymerase chain reaction for detection of Treponema pallidum, herpes simplex-1\/2 and Haemophilus ducreyi in genital, anal and oropharyngeal ulcers","volume":"20","author":"Glatz","year":"2014","journal-title":"Clin Microbiol Infect"},{"issue":"6","key":"10.1016\/j.cmi.2023.08.015_bib14","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1093\/cid\/ciy558","article-title":"Performance of treponemal tests for the diagnosis of syphilis","volume":"68","author":"Park","year":"2019","journal-title":"Clin Infect Dis"}],"container-title":["Clinical Microbiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1198743X23003981?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1198743X23003981?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T07:36:39Z","timestamp":1761118599000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1198743X23003981"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12]]},"references-count":14,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2023,12]]}},"alternative-id":["S1198743X23003981"],"URL":"https:\/\/doi.org\/10.1016\/j.cmi.2023.08.015","relation":{},"ISSN":["1198-743X"],"issn-type":[{"value":"1198-743X","type":"print"}],"subject":[],"published":{"date-parts":[[2023,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Anti-Treponema pallidum IgA response as a potential diagnostic marker of syphilis","name":"articletitle","label":"Article Title"},{"value":"Clinical Microbiology and Infection","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cmi.2023.08.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier Ltd on behalf of European Society of Clinical Microbiology and Infectious Diseases.","name":"copyright","label":"Copyright"}]}}