{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T20:56:39Z","timestamp":1790196999123,"version":"4.1.0"},"reference-count":30,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001459","name":"Ministry of Education - Singapore","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001459","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalmicrobiologyandinfection.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Microbiology and Infection"],"published-print":{"date-parts":[[2024,4]]},"DOI":"10.1016\/j.cmi.2023.12.019","type":"journal-article","created":{"date-parts":[[2023,12,21]],"date-time":"2023-12-21T21:54:31Z","timestamp":1703195671000},"page":"531-539","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"title":["Long-term neuropsychiatric sequelae of Delta versus Omicron SARS-CoV-2 infection"],"prefix":"10.1016","volume":"30","author":[{"given":"Liang En","family":"Wee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jue Tao","family":"Lim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"An Ting","family":"Tay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deanette","family":"Pang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Borame","family":"Dickens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Calvin J.","family":"Chiew","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Ong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David Chien Boon","family":"Lye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelvin Bryan","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cmi.2023.12.019_bib1","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1126\/science.abm2052","article-title":"Nervous system consequences of COVID\u201319","volume":"375","author":"Spudich","year":"2022","journal-title":"Science"},{"key":"10.1016\/j.cmi.2023.12.019_bib2","doi-asserted-by":"crossref","first-page":"1604","DOI":"10.1001\/jama.2022.18931","article-title":"Estimated global proportions of individuals with persistent fatigue, cognitive, and respiratory symptom clusters following symptomatic COVID-19 in 2020 and 2021","volume":"328","author":"Global Burden of Disease Long COVID Collaborators","year":"2022","journal-title":"JAMA"},{"key":"10.1016\/j.cmi.2023.12.019_bib3","doi-asserted-by":"crossref","first-page":"2406","DOI":"10.1038\/s41591-022-02001-z","article-title":"Long-term neurologic outcomes of COVID-19","volume":"28","author":"Xu","year":"2022","journal-title":"Nat Med"},{"key":"10.1016\/j.cmi.2023.12.019_bib4","doi-asserted-by":"crossref","DOI":"10.1136\/bmj-2021-068993","article-title":"Risks of mental health outcomes in people with Covid-19: cohort study","volume":"376","author":"Xie","year":"2022","journal-title":"BMJ"},{"key":"10.1016\/j.cmi.2023.12.019_bib5","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.bbi.2022.04.013","article-title":"Six-month sequelae of post-vaccination SARS-CoV-2 infection: a retrospective cohort study of 10,024 breakthrough infections","volume":"103","author":"Taquet","year":"2022","journal-title":"Brain Behav Immun"},{"key":"10.1016\/j.cmi.2023.12.019_bib6","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.bbi.2023.05.014","article-title":"Risks of neurological and psychiatric sequelae 2 years after hospitalisation or intensive care admission with COVID-19 compared to admissions for other causes","volume":"112","author":"Ley","year":"2023","journal-title":"Brain Behav Immun"},{"key":"10.1016\/j.cmi.2023.12.019_bib7","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1016\/S2215-0366(22)00260-7","article-title":"Neurological and psychiatric risk trajectories after SARS-CoV-2 infection: an analysis of 2-year retrospective cohort studies including 1 284 437 patients","volume":"9","author":"Taquet","year":"2022","journal-title":"Lancet Psychiatry"},{"key":"10.1016\/j.cmi.2023.12.019_bib8","doi-asserted-by":"crossref","first-page":"102000","DOI":"10.1016\/j.eclinm.2023.102000","article-title":"Long\u2013term post\u2013acute sequelae of COVID\u201319 infection: a retrospective, multi\u2013database cohort study in Hong Kong and the UK","volume":"60","author":"Lam","year":"2023","journal-title":"EClinicalMedicine"},{"issue":"1","key":"10.1016\/j.cmi.2023.12.019_bib9","article-title":"Association of SARS-CoV-2 infection with psychological distress, psychotropic prescribing, fatigue, and sleep problems among UK primary care patients","volume":"4","author":"Abel","year":"2021","journal-title":"JAMA Netw Open"},{"issue":"1","key":"10.1016\/j.cmi.2023.12.019_bib10","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1001\/jamapsychiatry.2022.1067","article-title":"Neuropsychiatric ramifications of severe COVID-19 and other severe acute respiratory infections","volume":"79","author":"Clift","year":"2022","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.cmi.2023.12.019_bib11","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1001\/jamapsychiatry.2023.1265","article-title":"COVID\u201319 and risk for mental disorders among adults in Denmark","volume":"80","author":"Nersesjan","year":"2023","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.cmi.2023.12.019_bib12","doi-asserted-by":"crossref","first-page":"1930","DOI":"10.1093\/cid\/ciad045","article-title":"Severe fatigue and persistent symptoms at three months following SARS\u2013CoV\u20132 infections during the pre\u2013delta, delta, and omicron time periods: a multicenter prospective cohort study","volume":"76","author":"Gottlieb","year":"2023","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.cmi.2023.12.019_bib13","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1038\/s41591-022-01840-0","article-title":"Long COVID after breakthrough SARS\u2013CoV\u20132 infection","volume":"28","author":"Al-Aly","year":"2022","journal-title":"Nat Med"},{"key":"10.1016\/j.cmi.2023.12.019_bib14","unstructured":"Ministry of Health, Singapore Adjusting our approach to manage the Omicron variant. https:\/\/www.moh.gov.sg\/news\u2013highlights\/details\/adjusting\u2013our\u2013approach\u2013to\u2013manage\u2013the\u2013omicron\u2013variant_26Dec2021. Accessed 15th November 2023"},{"key":"10.1016\/j.cmi.2023.12.019_bib15","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1016\/S0140-6736(21)00252-X","article-title":"Singapore's health\u2013care system: key features, challenges, and shifts","volume":"398","author":"Tan","year":"2021","journal-title":"Lancet"},{"key":"10.1016\/j.cmi.2023.12.019_bib16","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1093\/cid\/ciad345","volume":"77","author":"Wee","year":"2023","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.cmi.2023.12.019_bib17","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1186\/s12939-021-01554-8","article-title":"Leveraging open data to reconstruct the Singapore housing index and other building\u2013level markers of socioeconomic status for health services research","volume":"20","author":"Lim","year":"2021","journal-title":"Int J Equity Health"},{"key":"10.1016\/j.cmi.2023.12.019_bib18","doi-asserted-by":"crossref","first-page":"e68","DOI":"10.7861\/clinmed.2020-0204","article-title":"Long\u2013term sequelae following previous coronavirus epidemics","volume":"21","author":"O\u2019Sullivan","year":"2021","journal-title":"Clin Med (Lond)"},{"key":"10.1016\/j.cmi.2023.12.019_bib19","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.jaci.2018.11.015","article-title":"The microbiome in patients with atopic dermatitis","volume":"143","author":"Paller","year":"2019","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.cmi.2023.12.019_bib20","doi-asserted-by":"crossref","first-page":"2405","DOI":"10.1002\/oby.22995","article-title":"Ethnicity, neighborhood and individual socioeconomic status, and obesity: the Singapore multiethnic cohort","volume":"28","author":"Park","year":"2020","journal-title":"Obesity (Silver Spring)"},{"key":"10.1016\/j.cmi.2023.12.019_bib21","doi-asserted-by":"crossref","first-page":"2347","DOI":"10.1038\/s41591-023-02521-2","article-title":"Postacute sequelae of COVID-19 at 2 years","volume":"29","author":"Bowe","year":"2023","journal-title":"Nat Med"},{"key":"10.1016\/j.cmi.2023.12.019_bib22","doi-asserted-by":"crossref","first-page":"1948","DOI":"10.1038\/s41467-023-37653-z","article-title":"Data\u2013driven analysis to understand long COVID using electronic health records from the RECOVER initiative","volume":"14","author":"Zang","year":"2023","journal-title":"Nat Commun"},{"key":"10.1016\/j.cmi.2023.12.019_bib23","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1001\/jamainternmed.2023.2228","article-title":"Comparison of medical and mental health sequelae following hospitalization for COVID\u201319, influenza, and sepsis","volume":"183","author":"Quinn","year":"2023","journal-title":"JAMA Intern Med"},{"key":"10.1016\/j.cmi.2023.12.019_bib24","article-title":"Genesis, evolution and effectiveness of Singapore\u2019s national sorting logic and home recovery policies in handling the COVID\u201319 Delta and Omicron waves","volume":"35","author":"Yau","year":"2023","journal-title":"Lancet Reg Health West Pac"},{"key":"10.1016\/j.cmi.2023.12.019_bib25","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.bbi.2023.01.010","article-title":"Blood\u2013brain barrier penetration of non\u2013replicating SARS\u2013CoV\u20132 and S1 variants of concern induce neuroinflammation which is accentuated in a mouse model of Alzheimer\u2019s disease","volume":"109","author":"Erickson","year":"2023","journal-title":"Brain Behav Immun"},{"key":"10.1016\/j.cmi.2023.12.019_bib26","doi-asserted-by":"crossref","first-page":"100648","DOI":"10.1016\/j.bbih.2023.100648","article-title":"Neurophenotypes of COVID\u201319: risk factors and recovery outcomes","volume":"30","author":"Prabhakaran","year":"2023","journal-title":"Brain Behav Immun Health"},{"key":"10.1016\/j.cmi.2023.12.019_bib27","doi-asserted-by":"crossref","first-page":"4485","DOI":"10.1038\/s41467-023-40228-7","article-title":"Neuroinvasion and anosmia are independent phenomena upon infection with SARS\u2013CoV\u20132 and its variants","volume":"14","author":"de Melo","year":"2023","journal-title":"Nat Commun"},{"key":"10.1016\/j.cmi.2023.12.019_bib28","doi-asserted-by":"crossref","first-page":"2409","DOI":"10.1007\/s00415-023-11661-x","article-title":"COVID19\u2013associated new\u2013onset movement disorders: a follow\u2013up study","volume":"270","author":"Schneider","year":"2023","journal-title":"J Neurol"},{"key":"10.1016\/j.cmi.2023.12.019_bib29","doi-asserted-by":"crossref","first-page":"249","DOI":"10.47102\/annals-acadmedsg.202341","article-title":"Risk and protective factors of mental health during the COVID\u201319 pandemic: a cross\u2013sectional study in Singapore","volume":"52","author":"Mythily","year":"2023","journal-title":"Ann Acad Med Singapore"},{"key":"10.1016\/j.cmi.2023.12.019_bib30","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1016\/S2215-0366(20)30287-X","article-title":"Neurological and neuropsychiatric complications of COVID-19 in 153 patients: a UK-wide surveillance study","volume":"7","author":"Varatharaj","year":"2020","journal-title":"Lancet Psychiatry"}],"container-title":["Clinical Microbiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1198743X23006274?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1198743X23006274?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T18:11:04Z","timestamp":1762366264000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1198743X23006274"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4]]},"references-count":30,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,4]]}},"alternative-id":["S1198743X23006274"],"URL":"https:\/\/doi.org\/10.1016\/j.cmi.2023.12.019","relation":{},"ISSN":["1198-743X"],"issn-type":[{"value":"1198-743X","type":"print"}],"subject":[],"published":{"date-parts":[[2024,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Long-term neuropsychiatric sequelae of Delta versus Omicron SARS-CoV-2 infection","name":"articletitle","label":"Article Title"},{"value":"Clinical Microbiology and Infection","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cmi.2023.12.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}