{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T12:22:40Z","timestamp":1787660560209,"version":"build-2736575974"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T00:00:00Z","timestamp":1785456000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005762","name":"National Taiwan University Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005762","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalmicrobiologyandinfection.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Microbiology and Infection"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.cmi.2026.07.048","type":"journal-article","created":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T15:59:13Z","timestamp":1785772753000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Two-year durability of MVA-BN vaccine-induced antibodies and the risk of Mpox breakthrough infections among high-risk populations: a prospective, longitudinal study"],"prefix":"10.1016","author":[{"given":"Wang-Da","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ut Man","family":"Chan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tai-Ling","family":"Chao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai-Hsiang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hsin-Yun","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuan-Yin","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Shan","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chi-Ying","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming-Chieh","family":"Shih","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guei-Chi","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Chun","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng-Hsin","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Ching","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chia-Yi","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chih-Hao","family":"Hung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling-Ya","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Zhen","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hsi-Yen","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei-Ying","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Ting","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting-Kai","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wang-Huei","family":"Sheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Szu-Min","family":"Hsieh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shih-Chung","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sui-Yuan","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chien-Ching","family":"Hung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cmi.2026.07.048_bib1","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.3390\/v17121526","article-title":"Mpox: Exploring epidemiology, disease outcomes, and preventative vaccination among people with HIV during the ongoing outbreaks","volume":"17","author":"Orkin","year":"2025","journal-title":"Viruses"},{"key":"10.1016\/j.cmi.2026.07.048_bib2","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1016\/S1473-3099(24)00531-0","article-title":"Temporary adaptations to sexual behaviour during the Mpox outbreak in 23 countries in Europe and the Americas: Findings from a retrospective cross-sectional online survey","volume":"24","author":"Prochazka","year":"2024","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.cmi.2026.07.048_bib3","doi-asserted-by":"crossref","first-page":"460","DOI":"10.15585\/mmwr.mm7320a3","article-title":"Monkeypox virus infections after 2 preexposure doses of JYNNEOS vaccine - United States, May 2022-May 2024","volume":"73","author":"Guagliardo","year":"2024","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"10.1016\/j.cmi.2026.07.048_bib4","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.jmii.2024.10.003","article-title":"Serum Mpox-specific IgG titers before and after breakthrough Mpox infection in an HIV-infected individual with viral suppression and prior 2-dose Mpox vaccination","volume":"58","author":"Liu","year":"2025","journal-title":"J Microbiol Immunol Infect"},{"key":"10.1016\/j.cmi.2026.07.048_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.lanprc.2025.100018","article-title":"Clinical features of Mpox in fully vaccinated people in New South Wales, Australia: An outbreak investigation and retrospective cohort study","volume":"1","author":"Latham","year":"2025","journal-title":"Lancet Primary Care"},{"key":"10.1016\/j.cmi.2026.07.048_bib6","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S1473-3099(23)00492-9","article-title":"Mpox in people with past infection or a complete vaccination course: A global case series","volume":"24","author":"Hazra","year":"2024","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.cmi.2026.07.048_bib7","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1016\/S1473-3099(25)00180-X","article-title":"Effect of JYNNEOS vaccination on Mpox clinical progression: A case-control study","volume":"25","author":"Granskog","year":"2025","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.cmi.2026.07.048_bib8","doi-asserted-by":"crossref","DOI":"10.1093\/ofid\/ofaf536","article-title":"Antibody responses are sustained 2 years post-Mpox infection but not following modified Vaccinia Ankara-Bavarian Nordic vaccination","volume":"12","author":"Byrne","year":"2025","journal-title":"Open Forum Infect Dis"},{"key":"10.1016\/j.cmi.2026.07.048_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijid.2025.107830","article-title":"Short-term evolution of Mpox-specific IgG and neutralizing antibodies among individuals undergoing MVA-BN vaccination","volume":"153","author":"Liu","year":"2025","journal-title":"Int J Infect Dis"},{"key":"10.1016\/j.cmi.2026.07.048_bib10","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1086\/380460","article-title":"Age distribution for T cell reactivity to vaccinia virus in a healthy population","volume":"38","author":"Hsieh","year":"2004","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.cmi.2026.07.048_bib11","doi-asserted-by":"crossref","DOI":"10.1093\/ofid\/ofag018","article-title":"Persistent immunity from historic smallpox vaccination and its limited cross-neutralization of Monkeypox virus: a population-based serological study in Taiwan","volume":"13","author":"Chen","year":"2026","journal-title":"Open Forum Infect Dis"},{"key":"10.1016\/j.cmi.2026.07.048_bib12","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.1001\/jama.2024.20951","article-title":"Decline of Mpox antibody responses after modified Vaccinia Ankara-Bavarian Nordic vaccination","volume":"332","author":"Collier","year":"2024","journal-title":"JAMA"},{"key":"10.1016\/j.cmi.2026.07.048_bib13","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1093\/infdis\/jiag009","article-title":"A humoral dilemma: Reassessing monkeypox virus neutralizing antibodies at more than two years from Mpox or MVA-BN vaccination","volume":"234","author":"Moschetta","year":"2026","journal-title":"J Infect Dis"},{"key":"10.1016\/j.cmi.2026.07.048_bib14","article-title":"Comparative humoral profiles in mpox cases, survivors, and vaccinated individuals reveal correlates of protection against MPXV","volume":"6","author":"Wang","year":"2025","journal-title":"Cell Rep Med"},{"key":"10.1016\/j.cmi.2026.07.048_bib15","doi-asserted-by":"crossref","first-page":"2396","DOI":"10.3390\/v15122396","article-title":"Neutralization Determinants on Poxviruses","volume":"15","author":"Riccardo","year":"2023","journal-title":"Viruses"},{"key":"10.1016\/j.cmi.2026.07.048_bib16","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1007\/s00253-024-13361-6","article-title":"Monkeypox virus A29L protein as the target for specific diagnosis and serological analysis","volume":"108","author":"Liang","year":"2024","journal-title":"Appl Microbiol Biotechnol"},{"key":"10.1016\/j.cmi.2026.07.048_bib17","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1007\/s00253-025-13466-6","article-title":"Monkeypox virus H3L protein as the target antigen for developing neutralizing antibody and serological assay","volume":"109","author":"Huang","year":"2025","journal-title":"Appl Microbiol Biotechnol"},{"key":"10.1016\/j.cmi.2026.07.048_bib18","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1016\/j.jmii.2024.08.008","article-title":"Clinical manifestations and viral kinetics of people with Mpox: A case series during the 2023 outbreak in Taiwan","volume":"57","author":"Chen","year":"2024","journal-title":"J Microbiol Immunol Infect"},{"key":"10.1016\/j.cmi.2026.07.048_bib19","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/j.jmii.2025.06.003","article-title":"Disproportionate presentation of Mpox among people with HIV: A multicenter retrospective cohort study in Taiwan","volume":"58","author":"Chen","year":"2025","journal-title":"J Microbiol Immunol Infect"},{"key":"10.1016\/j.cmi.2026.07.048_bib20","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1093\/infdis\/jiae515","article-title":"Monkeypox virus infection stimulates a more robust and durable neutralizing antibody response compared to Modified Vaccinia Virus Ankara vaccination","volume":"231","author":"Selverian","year":"2025","journal-title":"J Infect Dis."},{"key":"10.1016\/j.cmi.2026.07.048_bib21","doi-asserted-by":"crossref","first-page":"784","DOI":"10.3390\/v16050784","article-title":"Mpox (Monkeypox) virus and its co-infection with HIV, sexually transmitted infections, or bacterial superinfections: double whammy or a new prime culprit?","volume":"16","author":"Liu","year":"2024","journal-title":"Viruses"},{"key":"10.1016\/j.cmi.2026.07.048_bib22","doi-asserted-by":"crossref","first-page":"42","DOI":"10.7812\/TPP\/23.072","article-title":"Concurrent sexually transmitted infections with Mpox infections: A brief review","volume":"28","author":"Wick","year":"2024","journal-title":"Perm J"},{"key":"10.1016\/j.cmi.2026.07.048_bib23","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/S1473-3099(26)00001-0","article-title":"Immunogenicity and safety of MVA-BN vaccine administered 5 years after a two-dose primary series in DR Congo: A prospective cohort study","volume":"26","author":"Priyamvada","year":"2026","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.cmi.2026.07.048_bib24","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1038\/s41467-026-68335-1","article-title":"Sero-genomic evidence for occult mpox exposure in healthy Nigerian adults","volume":"17","author":"Abdullahi","year":"2026","journal-title":"Nat Commun"},{"key":"10.1016\/j.cmi.2026.07.048_bib25","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2022-254305","article-title":"Asymptomatic transmission of human mpox","volume":"17","author":"Mouro","year":"2024","journal-title":"BMJ Case Rep"},{"key":"10.1016\/j.cmi.2026.07.048_bib26","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0335729","article-title":"Screening for asymptomatic mpox in at-risk populations: A cross-sectional study","volume":"20","author":"Armenteros-Yeguas","year":"2025","journal-title":"PLoS One"},{"key":"10.1016\/j.cmi.2026.07.048_bib27","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.7326\/M22-2183","article-title":"Detection of Monkeypox virus in anorectal swabs from asymptomatic men who have sex with men in a sexually transmitted infection screening program in Paris, France","volume":"175","author":"Ferr\u00e9","year":"2022","journal-title":"Ann Intern Med."},{"key":"10.1016\/j.cmi.2026.07.048_bib28","doi-asserted-by":"crossref","DOI":"10.1002\/jmv.70498","article-title":"Low specific t-cell immunity against Mpox elicited in people with HIV-1 and PrEP users after subcutaneous vaccination compared to natural infection","volume":"97","author":"Calle-Jim\u00e9nez","year":"2025","journal-title":"J Med Virol"},{"key":"10.1016\/j.cmi.2026.07.048_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.lanmic.2024.101045","article-title":"Immunogenicity of MVA-BN vaccine deployed as mpox prophylaxis: A prospective, single-centre, cohort study and analysis of transcriptomic predictors of response","volume":"6","author":"Drennan","year":"2025","journal-title":"Lancet Microbe"}],"container-title":["Clinical Microbiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1198743X26004155?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1198743X26004155?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T11:36:33Z","timestamp":1787657793000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1198743X26004155"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":29,"alternative-id":["S1198743X26004155"],"URL":"https:\/\/doi.org\/10.1016\/j.cmi.2026.07.048","relation":{},"ISSN":["1198-743X"],"issn-type":[{"value":"1198-743X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Two-year durability of MVA-BN vaccine-induced antibodies and the risk of Mpox breakthrough infections among high-risk populations: a prospective, longitudinal study","name":"articletitle","label":"Article Title"},{"value":"Clinical Microbiology and Infection","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cmi.2026.07.048","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Ltd on behalf of European Society of Clinical Microbiology and Infectious Diseases.","name":"copyright","label":"Copyright"}]}}