{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T03:40:18Z","timestamp":1792726818241,"version":"4.5.0"},"reference-count":33,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalmicrobiologyandinfection.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Microbiology and Infection"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.cmi.2026.08.028","type":"journal-article","created":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T23:34:45Z","timestamp":1787787285000},"page":"1767-1772","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Update on malaria vaccine deployment and challenges in the field"],"prefix":"10.1016","volume":"32","author":[{"given":"H. Magloire","family":"Natama","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toussaint","family":"Rouamba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salou","family":"Diallo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Halidou","family":"Tinto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cmi.2026.08.028_bib1","series-title":"World Malaria Report. Geneva, Switzerland","year":"2025"},{"key":"10.1016\/j.cmi.2026.08.028_bib2","series-title":"Global technical strategy for malaria 2016\u20132030, 2021 update","year":"2021"},{"key":"10.1016\/j.cmi.2026.08.028_bib3","series-title":"WHO recommends groundbreaking malaria vaccine for children at risk","year":"2021"},{"key":"10.1016\/j.cmi.2026.08.028_bib4","series-title":"WHO recommends R21\/Matrix-M vaccine for malaria prevention in updated advice on immunization","year":"2023"},{"key":"10.1016\/j.cmi.2026.08.028_bib5","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1186\/s12982-024-00284-w","article-title":"A narrative review of the RTS S AS01 malaria vaccine and its implementation in Africa to reduce the global malaria burden","volume":"21","author":"Ogieuhi","year":"2024","journal-title":"Discov Public Heal"},{"key":"10.1016\/j.cmi.2026.08.028_bib6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12936-024-05235-z","article-title":"Routine malaria vaccination in Africa: A step toward malaria eradication?","volume":"24","author":"Sibomana","year":"2025","journal-title":"Malar J"},{"key":"10.1016\/j.cmi.2026.08.028_bib7","doi-asserted-by":"crossref","first-page":"e995","DOI":"10.1016\/S2214-109X(25)00096-8","article-title":"Safety of RTS,S\/AS01E malaria vaccine up to 1 year after the third dose in Ghana, Kenya, and Malawi (EPI-MAL-003): A phase 4 cohort event monitoring study","volume":"13","author":"Haine","year":"2025","journal-title":"Lancet Glob Heal"},{"key":"10.1016\/j.cmi.2026.08.028_bib8","doi-asserted-by":"crossref","DOI":"10.1002\/iid3.899","article-title":"Acceptance, availability, and feasibility of RTS, S\/AS01 malaria vaccine: A review","volume":"11","author":"Mumtaz","year":"2023","journal-title":"Immun Inflamm Dis"},{"key":"10.1016\/j.cmi.2026.08.028_bib9","article-title":"Policy uptake and implementation of the RTS,S\/AS01 malaria vaccine in sub-Saharan African countries: Status 2 years following the WHO recommendation","volume":"9","author":"Osoro","year":"2024","journal-title":"BMJ Glob Heal"},{"key":"10.1016\/j.cmi.2026.08.028_bib10","doi-asserted-by":"crossref","first-page":"2284","DOI":"10.1056\/NEJMoa1208394","article-title":"A phase 3 trial of RTS,S\/AS01 malaria vaccine in African infants","volume":"367","author":"RTS S Clinical Trials Partnership","year":"2012","journal-title":"N Engl J Med"},{"key":"10.1016\/j.cmi.2026.08.028_bib11","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/S0140-6736(23)02511-4","article-title":"Safety and efficacy of malaria vaccine candidate R21\/Matrix-M in African children: A multicentre, double-blind, randomised, phase 3 trial","volume":"403","author":"Datoo","year":"2024","journal-title":"Lancet"},{"key":"10.1016\/j.cmi.2026.08.028_bib12","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-021-90290-8","article-title":"Ultra-low dose immunization and multi-component vaccination strategies enhance protection against malaria in mice","volume":"11","author":"Collins","year":"2021","journal-title":"Sci Rep"},{"key":"10.1016\/j.cmi.2026.08.028_bib13","doi-asserted-by":"crossref","DOI":"10.1038\/srep46621","article-title":"Enhancing protective immunity to malaria with a highly immunogenic virus-like particle vaccine","volume":"7","author":"Collins","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.cmi.2026.08.028_bib14","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgph.0004549","article-title":"Performance characteristics and potential public health impact of improved pre-erythrocytic malaria vaccines targeting childhood burden","volume":"5","author":"Malinga","year":"2025","journal-title":"PLOS Glob Public Health"},{"key":"10.1016\/j.cmi.2026.08.028_bib17","doi-asserted-by":"crossref","first-page":"e672","DOI":"10.1016\/S2214-109X(24)00013-5","article-title":"Integration of the RTS,S\/AS01 malaria vaccine into the Essential Programme on Immunisation in western Kenya: A qualitative longitudinal study from the health system perspective","volume":"12","author":"Hill","year":"2024","journal-title":"Lancet Glob Heal"},{"key":"10.1016\/j.cmi.2026.08.028_bib20","article-title":"Factors affecting the access, delivery and adherence to RTS,S vaccination schedules of the expanded programme on immunization among caregivers in Ghana","volume":"8","author":"Odopey","year":"2023","journal-title":"BMJ Glob Heal"},{"key":"10.1016\/j.cmi.2026.08.028_bib21","doi-asserted-by":"crossref","first-page":"1801","DOI":"10.3390\/vaccines11121801","article-title":"Acceptance of and adherence to a four-dose RTS,S\/AS01 schedule: Findings from a Longitudinal Qualitative Evaluation Study for the Malaria Vaccine Implementation Programme","volume":"11","author":"Price","year":"2023","journal-title":"Vaccines"},{"key":"10.1016\/j.cmi.2026.08.028_bib22","doi-asserted-by":"crossref","first-page":"3215","DOI":"10.1016\/j.vaccine.2023.04.011","article-title":"Modelling the relative cost-effectiveness of the RTS,S\/AS01 malaria vaccine compared to investment in vector control or chemoprophylaxis","volume":"41","author":"Topazian","year":"2023","journal-title":"Vaccine"},{"key":"10.1016\/j.cmi.2026.08.028_bib23","article-title":"Delivery strategies for malaria vaccination in areas with seasonal malaria transmission","volume":"8","author":"Grant","year":"2023","journal-title":"BMJ Glob Heal"},{"key":"10.1016\/j.cmi.2026.08.028_bib24","first-page":"E1","article-title":"Vaccines hesitancy in Africa: How COVID-19 pandemic may affect malaria vaccination campaigns","volume":"63","author":"Sulemane","year":"2022","journal-title":"J Prev Med Hyg"},{"key":"10.1016\/j.cmi.2026.08.028_bib25","doi-asserted-by":"crossref","DOI":"10.3389\/fitd.2025.1691239","article-title":"Addressing malaria vaccine hesitancy in Nigeria: Lessons from the Pfizer-Kano incident and COVID-19 vaccination","volume":"6","author":"Suru","year":"2025","journal-title":"Front Trop Dis"},{"key":"10.1016\/j.cmi.2026.08.028_bib26","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1186\/s12936-023-04768-z","article-title":"Awareness and acceptability of malaria vaccine among caregivers of under-5 children in Northern Nigeria","volume":"22","author":"Ajayi","year":"2023","journal-title":"Malar J"},{"key":"10.1016\/j.cmi.2026.08.028_bib27","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1186\/s12936-024-04921-2","article-title":"Hesitancy towards R21\/Matrix-M malaria vaccine among Ghanaian parents and attitudes towards immunizing non-eligible children: A cross-sectional survey","volume":"23","author":"Hussein","year":"2024","journal-title":"Malar J"},{"key":"10.1016\/j.cmi.2026.08.028_bib28","first-page":"496","article-title":"Acceptability and uptake of RTS,S\/AS01 malaria vaccine 18 months after pilot introduction in Western Kenya","volume":"108","author":"Westercamp","year":"2023","journal-title":"Am J Trop Med Hyg"},{"key":"10.1016\/j.cmi.2026.08.028_bib29","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1186\/s12936-024-04995-y","article-title":"Community readiness and acceptance for the implementation of a novel malaria vaccine among at-risk children in sub-Saharan Africa: A systematic review protocol","volume":"23","author":"Kigongo","year":"2024","journal-title":"Malar J"},{"key":"10.1016\/j.cmi.2026.08.028_bib30","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0278224","article-title":"A systematic review and meta-analysis of the prevalence of caregiver acceptance of malaria vaccine for under-five children in low-income and middle-income countries (LMICs)","volume":"17","author":"Sulaiman","year":"2022","journal-title":"PLoS One"},{"key":"10.1016\/j.cmi.2026.08.028_bib31","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1186\/s12936-025-05778-9","article-title":"The Malaria Vaccine Implementation Programme study area in Ghana: Results of a household survey prior to the introduction of the RTS,S\/AS01 vaccine","volume":"25","author":"Welaga","year":"2026","journal-title":"Malar J"},{"key":"10.1016\/j.cmi.2026.08.028_bib32","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1186\/s12936-025-05484-6","article-title":"Subnational introduction of the RTS,S\/AS01E malaria vaccine into routine immunization: Experience and lessons from the three pilot countries","volume":"24","author":"Jalang\u2019o","year":"2025","journal-title":"Malar J"},{"key":"10.1016\/j.cmi.2026.08.028_bib33","doi-asserted-by":"crossref","first-page":"e61","DOI":"10.1016\/S2214-109X(25)00415-2","article-title":"Effectiveness of the RTS,S\/AS01E malaria vaccine in a real-world setting over 1 year of follow-up after the three-dose primary schedule: An interim analysis of a phase 4 study in Ghana, Kenya, and Malawi","volume":"14","author":"Ndeketa","year":"2026","journal-title":"Lancet Glob Heal"},{"key":"10.1016\/j.cmi.2026.08.028_bib34","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1056\/NEJMoa2026330","article-title":"Seasonal malaria vaccination with or without seasonal malaria chemoprevention","volume":"385","author":"Chandramohan","year":"2021","journal-title":"New Engl J Med"},{"key":"10.1016\/j.cmi.2026.08.028_bib35","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/s41182-023-00516-w","article-title":"Malaria vaccines: The 60-year journey of hope and final success\u2014lessons learned and future prospects","volume":"51","author":"El-Moamly","year":"2023","journal-title":"Trop Med Health"},{"key":"10.1016\/j.cmi.2026.08.028_bib36","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/S1473-3099(24)00752-7","article-title":"Safety and efficacy of the blood-stage malaria vaccine RH5.1\/Matrix-M in Burkina Faso: Interim results of a double-blind, randomised, controlled, phase 2b trial in children","volume":"25","author":"Natama","year":"2025","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.cmi.2026.08.028_bib37","doi-asserted-by":"crossref","DOI":"10.1056\/EVIDoa2400188","article-title":"A vaccine to block plasmodium falciparum transmission","volume":"4","author":"Healy","year":"2025","journal-title":"NEJM Evid"}],"container-title":["Clinical Microbiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1198743X26004775?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1198743X26004775?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T03:21:58Z","timestamp":1792725718000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1198743X26004775"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":33,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2026,11]]}},"alternative-id":["S1198743X26004775"],"URL":"https:\/\/doi.org\/10.1016\/j.cmi.2026.08.028","relation":{},"ISSN":["1198-743X"],"issn-type":[{"value":"1198-743X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Update on malaria vaccine deployment and challenges in the field","name":"articletitle","label":"Article Title"},{"value":"Clinical Microbiology and Infection","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cmi.2026.08.028","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}