{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T19:42:14Z","timestamp":1781206934583,"version":"3.54.1"},"reference-count":64,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2020YFC0862900"],"award-info":[{"award-number":["2020YFC0862900"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2020YFC0862904"],"award-info":[{"award-number":["2020YFC0862904"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2020YFC0862902"],"award-info":[{"award-number":["2020YFC0862902"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["U23A20486"],"award-info":[{"award-number":["U23A20486"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["12372300"],"award-info":[{"award-number":["12372300"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004826","name":"Natural Science Foundation of Beijing Municipality","doi-asserted-by":"publisher","award":["L241031"],"award-info":[{"award-number":["L241031"]}],"id":[{"id":"10.13039\/501100004826","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Computer Methods and Programs in Biomedicine"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.cmpb.2025.109164","type":"journal-article","created":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T11:43:51Z","timestamp":1763034231000},"page":"109164","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["The impact of arterial cannula direction in central venoarterial extracorporeal membrane oxygenation on aortic hemodynamic characteristics under various perfusion conditions"],"prefix":"10.1016","volume":"274","author":[{"given":"Yifeng","family":"Xi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongyu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaofei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1410-6901","authenticated-orcid":false,"given":"Bingyang","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3716-3156","authenticated-orcid":false,"given":"Zengsheng","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cmpb.2025.109164_bib0001","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1177\/0267659112468014","article-title":"ECMO cannula review","volume":"28","author":"Kohler","year":"2013","journal-title":"Perfusion"},{"key":"10.1016\/j.cmpb.2025.109164_bib0002","doi-asserted-by":"crossref","DOI":"10.1016\/j.hlc.2008.08.009","article-title":"Review of ECMO (Extra Corporeal Membrane Oxygenation) support in critically ill adult patients","volume":"17","author":"Marasco","year":"2008","journal-title":"Heart Lung Circ."},{"key":"10.1016\/j.cmpb.2025.109164_bib0003","first-page":"57","article-title":"Extracorporeal membrane oxygenation in adults","volume":"12","author":"Martinez","year":"2012","journal-title":"Contin. Educ. Anaesth. Crit. Care Pain"},{"key":"10.1016\/j.cmpb.2025.109164_bib0004","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1097\/MAT.0b013e3182904a52","article-title":"Extracorporeal Life Support Organization Registry Report 2012","volume":"59","author":"Paden","year":"2013","journal-title":"ASAIO J."},{"key":"10.1016\/j.cmpb.2025.109164_bib0005","doi-asserted-by":"crossref","first-page":"93","DOI":"10.21037\/acs.2018.11.03","article-title":"The Extracorporeal Life Support Organization Registry: update and perspectives","volume":"8","author":"Lorusso","year":"2019","journal-title":"Ann. Cardiothorac. Surg."},{"key":"10.1016\/j.cmpb.2025.109164_bib0006","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1177\/02676591221114954","article-title":"Venoarterial extracorporeal membrane oxygenation for postcardiotomy cardiogenic shock: the impact of cannulation strategy on survival","volume":"38","author":"Alhijab","year":"2023","journal-title":"Perfusion"},{"key":"10.1016\/j.cmpb.2025.109164_bib0007","doi-asserted-by":"crossref","unstructured":"Ramaiah C, Babu A. ECMO cannulation techniques. Extracorporeal membrane oxygenation: advances in therapy. 2016.","DOI":"10.5772\/64338"},{"key":"10.1016\/j.cmpb.2025.109164_bib0008","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCHEARTFAILURE.118.004905","article-title":"Venoarterial extracorporeal membrane oxygenation for cardiogenic shock and cardiac arrest","volume":"11","author":"Rao","year":"2018","journal-title":"Circ. Heart. Fail."},{"key":"10.1016\/j.cmpb.2025.109164_bib0009","doi-asserted-by":"crossref","first-page":"2087","DOI":"10.1053\/j.jvca.2018.03.016","article-title":"Clinical outcomes of adult patients who receive extracorporeal membrane oxygenation for postcardiotomy cardiogenic shock: A systematic review and meta-analysis","volume":"32","author":"Wang","year":"2018","journal-title":"J. Cardiothorac. Vasc. Anesth."},{"key":"10.1016\/j.cmpb.2025.109164_bib0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhlto.2023.100044","article-title":"Afterload pressure and left ventricular contractility synergistically affect left atrial pressure during veno-arterial ECMO","volume":"3","author":"Jiang","year":"2024","journal-title":"JHLT Open"},{"key":"10.1016\/j.cmpb.2025.109164_bib0011","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1055\/s-0030-1250005","article-title":"Peripheral versus central cannulation for extracorporeal membrane oxygenation: a comparison of limb ischemia and transfusion requirements","volume":"58","author":"Kanji","year":"2010","journal-title":"Thorac. Cardiovasc. Surg."},{"key":"10.1016\/j.cmpb.2025.109164_bib0012","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1111\/jocs.14526","article-title":"Central vs peripheral venoarterial ECMO in postcardiotomy cardiogenic shock","volume":"35","author":"Djordjevic","year":"2020","journal-title":"J. Card. Surg."},{"key":"10.1016\/j.cmpb.2025.109164_bib0013","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1186\/s13613-018-0475-6","article-title":"Ischemic and hemorrhagic brain injury during venoarterial-extracorporeal membrane oxygenation","volume":"8","author":"Le Guennec","year":"2018","journal-title":"Ann. Intensive Care"},{"key":"10.1016\/j.cmpb.2025.109164_bib0014","doi-asserted-by":"crossref","first-page":"e34","DOI":"10.1016\/j.athoracsur.2010.06.019","article-title":"Central extracorporeal membrane oxygenation for septic shock in an adult with H1N1 influenza","volume":"90","author":"MacLaren","year":"2010","journal-title":"Ann. Thorac. Surg."},{"key":"10.1016\/j.cmpb.2025.109164_bib0015","first-page":"174","article-title":"Extracorporeal membrane oxygenation as bridge-to-decision in acute heart failure due to systemic light-chain amyloidosis","volume":"16","author":"Mancio Silva","year":"2015","journal-title":"Am. J. Case Rep."},{"key":"10.1016\/j.cmpb.2025.109164_bib0016","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1007\/s12630-019-01501-w","article-title":"North-south syndrome in veno-arterial extra-corporeal membrane oxygenator: the other Harlequin syndrome","volume":"67","author":"St-Arnaud","year":"2020","journal-title":"Can. J. Anaesth."},{"key":"10.1016\/j.cmpb.2025.109164_bib0017","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1186\/s13054-019-2541-3","article-title":"Limb ischemia in peripheral veno-arterial extracorporeal membrane oxygenation: a narrative review of incidence, prevention, monitoring, and treatment","volume":"23","author":"Bonicolini","year":"2019","journal-title":"Crit. Care"},{"key":"10.1016\/j.cmpb.2025.109164_bib0018","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1111\/aor.12880","article-title":"Cannulation-related complications on veno-arterial extracorporeal membrane oxygenation: prevalence and effect on mortality","volume":"41","author":"Wong","year":"2017","journal-title":"Artif. Organs"},{"key":"10.1016\/j.cmpb.2025.109164_bib0019","article-title":"The impact of ECMO lower limb cannulation on the aortic flow features under differential blood perfusion conditions","volume":"16","author":"Xi","year":"2022","journal-title":"Med. Nov. Technol. Devices"},{"key":"10.1016\/j.cmpb.2025.109164_bib0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.cmpb.2019.105041","article-title":"Numerical analysis of aortic hemodynamics under the support of venoarterial extracorporeal membrane oxygenation and intra-aortic balloon pump","volume":"182","author":"Gu","year":"2019","journal-title":"Comput. Methods Programs Biomed."},{"key":"10.1016\/j.cmpb.2025.109164_bib0021","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.jbiomech.2017.02.009","article-title":"Flow mixing during peripheral veno-arterial extra corporeal membrane oxygenation - A simulation study","volume":"55","author":"Stevens","year":"2017","journal-title":"J. Biomech."},{"key":"10.1016\/j.cmpb.2025.109164_bib0022","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1186\/s12938-018-0493-5","article-title":"Hemodynamic effects of perfusion level of peripheral ECMO on cardiovascular system","volume":"17","author":"Gu","year":"2018","journal-title":"Biomed. Eng. Online"},{"key":"10.1016\/j.cmpb.2025.109164_bib0023","doi-asserted-by":"crossref","first-page":"717","DOI":"10.12659\/MSM.895831","article-title":"Hemodynamic differences between Central ECMO and peripheral ECMO: A primary CFD study","volume":"22","author":"Gu","year":"2016","journal-title":"Med. Sci. Monit."},{"key":"10.1016\/j.cmpb.2025.109164_bib0024","first-page":"36","article-title":"Impact of peripheral venoarterial extracorporeal membrane oxygenation support for heart failure on systemic hemodynamics and aortic blood flow","author":"Li","year":"2024","journal-title":"Phys. Fluids"},{"key":"10.1016\/j.cmpb.2025.109164_bib0025","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1097\/MAT.0000000000001221","article-title":"A computational fluid dynamics study of the extracorporeal membrane oxygenation-failing heart circulation","volume":"67","author":"Nezami","year":"2021","journal-title":"ASAIO J."},{"key":"10.1016\/j.cmpb.2025.109164_bib0026","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1007\/s10237-025-01952-9","article-title":"A computational and experimental study of veno-arterial extracorporeal membrane oxygenation in cardiogenic shock: defining the trade-off between perfusion and afterload","volume":"24","author":"Gasparotti","year":"2025","journal-title":"Biomech. Model. Mechanobiol."},{"key":"10.1016\/j.cmpb.2025.109164_bib0027","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1161\/01.CIR.86.1.232","article-title":"Lumen diameter of normal human coronary arteries. Influence of age, sex, anatomic variation, and left ventricular hypertrophy or dilation","volume":"86","author":"Dodge","year":"1992","journal-title":"Circulation"},{"key":"10.1016\/j.cmpb.2025.109164_bib0028","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1007\/s12055-020-00999-w","article-title":"Vascular access in ECMO","volume":"37","author":"Pooboni","year":"2021","journal-title":"Indian j. thorac. cardiovasc. surg."},{"key":"10.1016\/j.cmpb.2025.109164_bib0029","doi-asserted-by":"crossref","DOI":"10.1016\/j.cmpb.2024.108204","article-title":"Effect of veno-arterial extracorporeal membrane oxygenation lower-extremity cannulation on intra-arterial flow characteristics, oxygen content, and thrombosis risk","author":"Xi","year":"2024","journal-title":"Comput. Methods Programs Biomed."},{"key":"10.1016\/j.cmpb.2025.109164_bib0030","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1007\/s40846-015-0053-4","article-title":"Influence of aortic outflow cannula orientation on epiaortic flow pattern during pulsed cardiopulmonary bypass","volume":"35","author":"Caruso","year":"2015","journal-title":"J. Med. Biol. Eng."},{"key":"10.1016\/j.cmpb.2025.109164_bib0031","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1007\/BF02469406","article-title":"Aortic cannulation for cardiopulmonary bypass","volume":"7","author":"Taguchi","year":"1977","journal-title":"Jpn. J. Surg."},{"key":"10.1016\/j.cmpb.2025.109164_bib0032","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1080\/10255842.2010.518565","article-title":"Tetrahedral vs. polyhedral mesh size evaluation on flow velocity and wall shear stress for cerebral hemodynamic simulation","volume":"14","author":"Spiegel","year":"2011","journal-title":"Comput. Methods Biomech. Biomed. Eng."},{"key":"10.1016\/j.cmpb.2025.109164_bib0033","first-page":"249","article-title":"Comparative study of Newtonian and non-Newtonian simulations of drug transport in a model drug-eluting stent","volume":"49","author":"Wang","year":"2012","journal-title":"Biorheology"},{"key":"10.1016\/j.cmpb.2025.109164_bib0034","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/S0012-3692(16)56164-9","article-title":"Basic hemodynamics and its role in disease processes","volume":"79","author":"Walker","year":"1981","journal-title":"Chest"},{"key":"10.1016\/j.cmpb.2025.109164_bib0035","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1016\/j.cmpb.2013.11.009","article-title":"Numerical simulation of patient-specific left ventricular model with both mitral and aortic valves by FSI approach","volume":"113","author":"Su","year":"2014","journal-title":"Comput. Methods Programs Biomed."},{"key":"10.1016\/j.cmpb.2025.109164_bib0036","doi-asserted-by":"crossref","unstructured":"Pedley TJ. The fluid mechanics of large blood vessels: The fluid mechanics of large blood vessel; 1980.","DOI":"10.1017\/CBO9780511896996"},{"key":"10.1016\/j.cmpb.2025.109164_bib0037","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1146\/annurev.fluid.32.1.347","article-title":"Flows in stenotic vessels","volume":"32","author":"Berger","year":"2000","journal-title":"Annu. Rev. Fluid Mech."},{"key":"10.1016\/j.cmpb.2025.109164_bib0038","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1002\/jmri.21387","article-title":"A new method for the determination of aortic pulse wave velocity using cross-correlation on 2D PCMR velocity data","volume":"27","author":"Fielden","year":"2008","journal-title":"J. Magn. Reson. Imaging"},{"key":"10.1016\/j.cmpb.2025.109164_bib0039","doi-asserted-by":"crossref","unstructured":"Pedley TJ. The fluid mechanics of large blood vessels: contents. 1980.","DOI":"10.1017\/CBO9780511896996"},{"key":"10.1016\/j.cmpb.2025.109164_bib0040","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1161\/01.RES.10.5.798","article-title":"Left ventricular function in mammals of greatly different size","volume":"10","author":"Holt","year":"1962","journal-title":"Circ. Res."},{"key":"10.1016\/j.cmpb.2025.109164_bib0041","doi-asserted-by":"crossref","first-page":"2153","DOI":"10.1007\/s10439-009-9760-8","article-title":"On coupling a lumped parameter heart model and a three-dimensional finite element aorta model","volume":"37","author":"Kim","year":"2009","journal-title":"Ann. Biomed. Eng."},{"key":"10.1016\/j.cmpb.2025.109164_bib0042","doi-asserted-by":"crossref","first-page":"2228","DOI":"10.1007\/s10439-012-0579-3","article-title":"Patient-specific multiscale modeling of blood flow for coronary artery bypass graft surgery","volume":"40","author":"Sankaran","year":"2012","journal-title":"Ann. Biomed. Eng."},{"key":"10.1016\/j.cmpb.2025.109164_bib0043","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/s12265-021-10143-7","article-title":"Simulation of fluid-structure interaction in extracorporeal membrane oxygenation circulatory support systems","volume":"15","author":"Nezami","year":"2022","journal-title":"J. Cardiovasc. Transl. Res."},{"key":"10.1016\/j.cmpb.2025.109164_bib0044","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1097\/MAT.0b013e318254833b","article-title":"Evaluation of eulerian and lagrangian models for hemolysis estimation","volume":"58","author":"Taskin","year":"2012","journal-title":"Asaio J."},{"key":"10.1016\/j.cmpb.2025.109164_bib0045","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-022-23159-z","article-title":"Blood flow but not cannula positioning influences the efficacy of Veno-Venous ECMO therapy","volume":"12","author":"Leoni","year":"2022","journal-title":"Sci. Rep."},{"key":"10.1016\/j.cmpb.2025.109164_bib0046","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1007\/s00285-016-0986-4","article-title":"Mathematical modeling of thrombus formation in idealized models of aortic dissection: initial findings and potential applications","volume":"73","author":"Menichini","year":"2016","journal-title":"J. Math. Biol."},{"key":"10.1016\/j.cmpb.2025.109164_bib0047","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1097\/MAT.0b013e318254833b","article-title":"Evaluation of eulerian and lagrangian models for hemolysis estimation","volume":"58","author":"Taskin","year":"2012","journal-title":"ASAIO J."},{"key":"10.1016\/j.cmpb.2025.109164_bib0048","doi-asserted-by":"crossref","DOI":"10.1115\/1.4007092","article-title":"A quantitative comparison of mechanical blood damage parameters in rotary ventricular assist devices: shear stress, exposure time and hemolysis index","volume":"134","author":"Fraser","year":"2012","journal-title":"J. Biomech. Eng."},{"key":"10.1016\/j.cmpb.2025.109164_bib0049","doi-asserted-by":"crossref","DOI":"10.1002\/cnm.2924","article-title":"Flow features and device-induced blood trauma in CF-VADs under a pulsatile blood flow condition: A CFD comparative study","volume":"34","author":"Chen","year":"2018","journal-title":"Int. J. Numer. Method. Biomed. Eng."},{"key":"10.1016\/j.cmpb.2025.109164_bib0050","first-page":"9","article-title":"The impact of a new arterial intravascular pump on aorta hemodynamic surrounding: A numerical study","author":"Li","year":"2022","journal-title":"Bioeng. (Basel)"},{"key":"10.1016\/j.cmpb.2025.109164_bib0051","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1111\/aor.12438","article-title":"Quantification of shear-induced platelet activation: high shear stresses for short exposure time","volume":"39","author":"Ding","year":"2015","journal-title":"Artif. Organs"},{"key":"10.1016\/j.cmpb.2025.109164_bib0052","first-page":"147","article-title":"Simulation of thrombosis in a stenotic microchannel: the effects of vWF-enhanced shear activation of platelets","author":"Wu","year":"2020","journal-title":"Int. J. Eng. Sci."},{"key":"10.1016\/j.cmpb.2025.109164_bib0053","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1007\/s10439-005-2951-z","article-title":"Computational model of device-induced thrombosis and thromboembolism","volume":"33","author":"Goodman","year":"2005","journal-title":"Ann. Biomed. Eng."},{"key":"10.1016\/j.cmpb.2025.109164_bib0054","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1056\/NEJMra0801082","article-title":"Mechanisms of thrombus formation","volume":"359","author":"Furie","year":"2008","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.cmpb.2025.109164_bib0055","doi-asserted-by":"crossref","first-page":"4413","DOI":"10.1182\/blood.V90.11.4413","article-title":"Analysis of the involvement of the von Willebrand factor-glycoprotein Ib interaction in platelet adhesion to a collagen-coated surface under flow conditions","volume":"90","author":"Moroi","year":"1997","journal-title":"Blood"},{"key":"10.1016\/j.cmpb.2025.109164_bib0056","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1111\/aor.12542","article-title":"Numerical analysis of blood damage potential of the HeartMate II and HeartWare HVAD rotary blood pumps","volume":"39","author":"Thamsen","year":"2015","journal-title":"Artif. Organs"},{"key":"10.1016\/j.cmpb.2025.109164_bib0057","doi-asserted-by":"crossref","first-page":"657","DOI":"10.4070\/kcj.2019.0188","article-title":"Clinical pearls of venoarterial extracorporeal membrane oxygenation for cardiogenic shock","volume":"49","author":"Choi","year":"2019","journal-title":"Korean Circ. J."},{"key":"10.1016\/j.cmpb.2025.109164_bib0058","doi-asserted-by":"crossref","DOI":"10.1186\/s12890-015-0003-5","article-title":"Low oxygen saturation and mortality in an adult cohort: the Troms\u00f8 study","volume":"15","author":"Vold","year":"2015","journal-title":"BMC Pulm. Med."},{"key":"10.1016\/j.cmpb.2025.109164_bib0059","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1186\/cc10351","article-title":"Clinical review: use of venous oxygen saturations as a goal - a yet unfinished puzzle","volume":"15","author":"van Beest","year":"2011","journal-title":"Crit. Care"},{"key":"10.1016\/j.cmpb.2025.109164_bib0060","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/s13246-022-01203-6","article-title":"The effect of arterial cannula tip position on differential hypoxemia during venoarterial extracorporeal membrane oxygenation","volume":"46","author":"Wickramarachchi","year":"2023","journal-title":"Phys. Eng. Sci. Med."},{"key":"10.1016\/j.cmpb.2025.109164_bib0061","doi-asserted-by":"crossref","DOI":"10.1007\/s13239-024-00739-w","article-title":"Investigations of differential hypoxemia during venoarterial membrane oxygenation with and without impella support","author":"Neidlin","year":"2024","journal-title":"Cardiovasc. Eng. Technol."},{"key":"10.1016\/j.cmpb.2025.109164_bib0062","article-title":"The impact of traditional vs parallel venous\u2013arterial extracorporeal membrane oxygenation on the intra-aortic hemodynamic environment: A numerical study","author":"Xi","year":"2025","journal-title":"Phys. Fluids"},{"key":"10.1016\/j.cmpb.2025.109164_bib0063","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbiomech.2021.110393","article-title":"Refining a numerical model for device-induced thrombosis and investigating the effects of non-Newtonian blood models","volume":"120","author":"Yang","year":"2021","journal-title":"J. Biomech."},{"key":"10.1016\/j.cmpb.2025.109164_bib0064","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1097\/MAT.0000000000001202","article-title":"Central versus peripheral arterial cannulation for veno-arterial extracorporeal membrane oxygenation in post-cardiotomy patients","volume":"67","author":"Radakovic","year":"2021","journal-title":"ASAIO J."}],"container-title":["Computer Methods and Programs in Biomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0169260725005802?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0169260725005802?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T23:52:05Z","timestamp":1766101925000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0169260725005802"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":64,"alternative-id":["S0169260725005802"],"URL":"https:\/\/doi.org\/10.1016\/j.cmpb.2025.109164","relation":{},"ISSN":["0169-2607"],"issn-type":[{"value":"0169-2607","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The impact of arterial cannula direction in central venoarterial extracorporeal membrane oxygenation on aortic hemodynamic characteristics under various perfusion conditions","name":"articletitle","label":"Article Title"},{"value":"Computer Methods and Programs in Biomedicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cmpb.2025.109164","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"109164"}}