{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T07:21:12Z","timestamp":1790407272191,"version":"4.1.0"},"reference-count":62,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T00:00:00Z","timestamp":1776038400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001602","name":"Science Foundation Ireland","doi-asserted-by":"publisher","award":["16\/RC\/3872"],"award-info":[{"award-number":["16\/RC\/3872"]}],"id":[{"id":"10.13039\/501100001602","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010665","name":"H2020 Marie Sk\u0142odowska-Curie Actions","doi-asserted-by":"publisher","award":["101023041"],"award-info":[{"award-number":["101023041"]}],"id":[{"id":"10.13039\/100010665","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010661","name":"Horizon 2020 Framework Programme","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010661","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002081","name":"Irish Research Council","doi-asserted-by":"publisher","award":["GOIPG\/2022\/2032"],"award-info":[{"award-number":["GOIPG\/2022\/2032"]}],"id":[{"id":"10.13039\/501100002081","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Computer Methods and Programs in Biomedicine"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.cmpb.2026.109361","type":"journal-article","created":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T23:09:02Z","timestamp":1775516942000},"page":"109361","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["In silico modeling of transcatheter heart valve oversizing and ellipticity, Part II: Effects on leaflet mechanics, hemodynamics, and stent deflection contributing to thrombogenic risk and structural degeneration"],"prefix":"10.1016","volume":"281","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0186-0777","authenticated-orcid":false,"given":"Sam","family":"Boxwell","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel M.E.","family":"Cahalane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dylan","family":"Armfield","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Hickey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott","family":"Cook","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Kelly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4824-427X","authenticated-orcid":false,"given":"Philip","family":"Cardiff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laoise M.","family":"McNamara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cmpb.2026.109361_bib0001","series-title":"Valvular Heart Disease: the Next Cardiac Epidemic","first-page":"91","author":"d'Arcy","year":"2011"},{"issue":"4","key":"10.1016\/j.cmpb.2026.109361_bib0002","doi-asserted-by":"crossref","first-page":"e25","DOI":"10.1016\/j.jacc.2020.11.018","article-title":"2020 ACC\/AHA guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology\/American Heart Association Joint Committee on Clinical Practice Guidelines","volume":"77","author":"Members","year":"2021","journal-title":"J. Am. Coll. Cardiol."},{"issue":"21","key":"10.1016\/j.cmpb.2026.109361_bib0003","doi-asserted-by":"crossref","first-page":"2054","DOI":"10.1016\/j.jacc.2022.08.787","article-title":"National trends in TAVR and SAVR for patients with severe isolated aortic stenosis","volume":"80","author":"Sharma","year":"2022","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.cmpb.2026.109361_bib0004","first-page":"1","article-title":"Long-term outcomes and device failure after TAVI","author":"Barbanti","year":"2023","journal-title":"Nat. Rev. Cardiol."},{"issue":"1","key":"10.1016\/j.cmpb.2026.109361_bib0005","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.jcct.2013.12.020","article-title":"Oversizing in transcatheter aortic valve replacement, a commonly used term but a poorly understood one: dependency on definition and geometrical measurements","volume":"8","author":"Blanke","year":"2014","journal-title":"J. Cardiovasc. Comput. Tomogr."},{"issue":"3","key":"10.1016\/j.cmpb.2026.109361_bib0006","first-page":"508","article-title":"Multicenter evaluation of transcatheter aortic valve replacement using either SAPIEN XT or C ore V alve: degree of device oversizing by computed-tomography and clinical outcomes","volume":"86","author":"Dvir","year":"2015","journal-title":"Catheter. Cardiovas. Interven."},{"key":"10.1016\/j.cmpb.2026.109361_bib0007","doi-asserted-by":"crossref","first-page":"1989","DOI":"10.1007\/s10439-014-1051-3","article-title":"Simulation of self expanding transcatheter aortic valve in a realistic aortic root: implications of deployment geometry on leaflet deformation","volume":"42","author":"Gunning","year":"2014","journal-title":"Ann. Biomed. Eng."},{"issue":"4","key":"10.1016\/j.cmpb.2026.109361_bib0008","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1161\/CIRCULATIONAHA.117.030729","article-title":"Standardized definition of structural valve degeneration for surgical and transcatheter bioprosthetic aortic valves","volume":"137","author":"Dvir","year":"2018","journal-title":"Circulation"},{"issue":"6","key":"10.1016\/j.cmpb.2026.109361_bib0009","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1007\/s10439-014-1008-6","article-title":"An In vitro evaluation of the impact of eccentric deployment on transcatheter aortic valve hemodynamics","volume":"42","author":"Gunning","year":"2014","journal-title":"Ann. Biomed. Eng."},{"key":"10.1016\/j.cmpb.2026.109361_bib0010","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/j.actbio.2021.04.046","article-title":"Collagen fibre-mediated mechanical damage increases calcification of bovine pericardium for use in bioprosthetic heart valves","volume":"128","author":"Whelan","year":"2021","journal-title":"Acta Biomater."},{"issue":"3","key":"10.1016\/j.cmpb.2026.109361_bib0011","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/S0003-4975(10)65930-9","article-title":"Tissue buckling as a mechanism of bioprosthetic valve failure","volume":"46","author":"Vesely","year":"1988","journal-title":"Ann. Thorac. Surg."},{"key":"10.1016\/j.cmpb.2026.109361_bib0012","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.actbio.2023.07.044","article-title":"Multiscale multimodal characterization and simulation of structural alterations in failed bioprosthetic heart valves","volume":"169","author":"Tsolaki","year":"2023","journal-title":"Acta Biomater."},{"issue":"45","key":"10.1016\/j.cmpb.2026.109361_bib0013","doi-asserted-by":"crossref","first-page":"3382","DOI":"10.1093\/eurheartj\/ehx303","volume":"38","author":"Capodanno","year":"2017","journal-title":"Eur. Heart. J."},{"key":"10.1016\/j.cmpb.2026.109361_bib0014","doi-asserted-by":"crossref","DOI":"10.1016\/j.jmbbm.2021.104745","article-title":"Simulating the time evolving geometry, mechanical properties, and fibrous structure of bioprosthetic heart valve leaflets under cyclic loading","volume":"123","author":"Zhang","year":"2021","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"10.1016\/j.cmpb.2026.109361_bib0015","series-title":"Computational Hemodynamic Indices to Identify Transcatheter Aortic Valve Implantation Degeneration","author":"Crugnola","year":"2024"},{"issue":"12","key":"10.1016\/j.cmpb.2026.109361_bib0016","article-title":"Numerical models for assessing the risk of leaflet thrombosis post-transcatheter aortic valve-in-valve implantation","volume":"7","author":"Mayo","year":"2020","journal-title":"R. Soc. Open. Sci."},{"issue":"5","key":"10.1016\/j.cmpb.2026.109361_bib0017","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1016\/j.jcin.2015.03.005","article-title":"Thrombus formation following transcatheter aortic valve replacement","volume":"8","author":"De Marchena","year":"2015","journal-title":"JACC Cardiovas. Interven."},{"issue":"4","key":"10.1016\/j.cmpb.2026.109361_bib0018","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1177\/0885328212465482","article-title":"A comparative study of bovine and porcine pericardium to highlight their potential advantages to manufacture percutaneous cardiovascular implants","volume":"28","author":"Gauvin","year":"2013","journal-title":"J. Biomater. Appl."},{"issue":"2","key":"10.1016\/j.cmpb.2026.109361_bib0019","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.bbrc.2004.05.166","article-title":"Pathologic high shear stress induces apoptosis events in human platelets","volume":"320","author":"Leytin","year":"2004","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"4","key":"10.1016\/j.cmpb.2026.109361_bib0020","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.1007\/s10439-010-9936-2","article-title":"High-shear stress sensitizes platelets to subsequent low-shear conditions","volume":"38","author":"Sheriff","year":"2010","journal-title":"Ann. Biomed. Eng."},{"issue":"5","key":"10.1016\/j.cmpb.2026.109361_bib0021","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1016\/j.jacc.2018.10.083","article-title":"Durability of transcatheter and surgical bioprosthetic aortic valves in patients at lower surgical risk","volume":"73","author":"S\u00f8ndergaard","year":"2019","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.cmpb.2026.109361_bib0022","article-title":"In Silico fatigue optimization of TAVR stent designs with physiological motion in a beating heart model","author":"Baylous","year":"2023","journal-title":"Comput. Methods Prog. Biomed."},{"key":"10.1016\/j.cmpb.2026.109361_bib0023","doi-asserted-by":"crossref","DOI":"10.1016\/j.jmbbm.2024.106650","article-title":"Effect of bioprosthetic leaflet anisotropy on stent dynamics of transcatheter aortic valve replacement devices","author":"Armfield","year":"2024","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"10.1016\/j.cmpb.2026.109361_bib0024","doi-asserted-by":"crossref","first-page":"109404","DOI":"10.1016\/j.cmpb.2026.109404","article-title":"In Silico Modeling of Transcatheter Heart Valve Oversizing and Ellipticity, Part I: Establishing Credibility of an Advanced Model","author":"Boxwell","year":"2026","journal-title":"Comput. Methods Programs Biomed."},{"key":"10.1016\/j.cmpb.2026.109361_bib0025","unstructured":"ISO, \"ISO 5840-1:2021 - cardiovascular implants \u2014 Cardiac valve prostheses \u2014 Part 1: general requirements,\" 2021."},{"key":"10.1016\/j.cmpb.2026.109361_bib0026","doi-asserted-by":"crossref","DOI":"10.1016\/j.jmbbm.2021.104621","article-title":"Transcatheter aortic valve replacement in bicuspid valves: the synergistic effects of eccentric and incomplete stent deployment","volume":"121","author":"Qiu","year":"2021","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"10.1016\/j.cmpb.2026.109361_bib0027","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.jbiomech.2016.12.031","article-title":"The impact of imperfect frame deployment and rotational orientation on stress within the prosthetic leaflets during transcatheter aortic valve implantation","volume":"53","author":"Bailey","year":"2017","journal-title":"J. Biomech."},{"issue":"12","key":"10.1016\/j.cmpb.2026.109361_bib0028","doi-asserted-by":"crossref","DOI":"10.1002\/cnm.3649","article-title":"Fluid\u2013structure interaction analysis of eccentricity and leaflet rigidity on thrombosis biomarkers in bioprosthetic aortic valve replacements","volume":"38","author":"Oks","year":"2022","journal-title":"Int. J. Numer. Method. Biomed. Eng."},{"key":"10.1016\/j.cmpb.2026.109361_bib0029","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1007\/s10439-016-1738-8","article-title":"Transcatheter valve underexpansion limits leaflet durability: implications for valve-in-valve procedures","volume":"45","author":"Martin","year":"2016","journal-title":"Ann. Biomed. Eng."},{"key":"10.1016\/j.cmpb.2026.109361_bib0030","first-page":"927","article-title":"Valve thrombosis following transcatheter aortic valve replacement: significance of blood stasis on the leaflets","volume":"51","author":"Vahidkhah","year":"2017","journal-title":"Eur. J. Card.-Thor. Surg."},{"issue":"17","key":"10.1016\/j.cmpb.2026.109361_bib0031","doi-asserted-by":"crossref","first-page":"1598","DOI":"10.1161\/CIRCULATIONAHA.117.029479","article-title":"The fluid mechanics of transcatheter heart valve leaflet thrombosis in the neosinus","volume":"136","author":"Midha","year":"2017","journal-title":"Circulation"},{"key":"10.1016\/j.cmpb.2026.109361_bib0032","article-title":"Leaflet mechanical stress in different designs and generations of transcatheter aortic valves: an in vitro study","author":"Stanov\u00e1","year":"2023","journal-title":"Structural Heart"},{"issue":"1","key":"10.1016\/j.cmpb.2026.109361_bib0033","article-title":"Inflow-to-outflow stent frame expansion, ellipticity, and decoupling in Evolut TAVR: implications for mid-term hemodynamic performance","volume":"4","author":"Puri","year":"2025","journal-title":"J. Soc. Cardiovasc. Angiogr. Interv."},{"key":"10.1016\/j.cmpb.2026.109361_bib0034","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.amjcard.2023.08.130","article-title":"Self-expandable prosthesis valve adaptation: non-uniform expansion and stent frame decoupling","volume":"207","author":"Moscarelli","year":"2023","journal-title":"Am. J. Cardiol."},{"key":"10.1016\/j.cmpb.2026.109361_bib0035","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.jmbbm.2019.05.020","article-title":"Evaluation of transcatheter heart valve biomaterials: computational modeling using bovine and porcine pericardium","volume":"97","author":"Sulejmani","year":"2019","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"10.1016\/j.cmpb.2026.109361_bib0036","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1007\/s10237-018-1069-9","article-title":"The impact of implantation depth of the Lotus\u2122 valve on mechanical stress in close proximity to the bundle of his","volume":"18","author":"McGee","year":"2019","journal-title":"Biomech. Model. Mechanobiol."},{"key":"10.1016\/j.cmpb.2026.109361_bib0037","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1115\/1.2049337","article-title":"Simulated bioprosthetic heart valve deformation under quasi-static loading","volume":"127","author":"Sun","year":"2005","journal-title":"J. Biomech. Eng."},{"issue":"2","key":"10.1016\/j.cmpb.2026.109361_bib0038","first-page":"e130","article-title":"TAVI with the ACURATE neo2 in severe bicuspid aortic valve stenosis: the Neo2 BAV Registry","volume":"21","author":"Ruck","year":"2025","journal-title":"EuroIntervention J. EuroPCR Collab. Work. Group Intervent. Cardiol. Eur. Soc. Cardiol."},{"issue":"9","key":"10.1016\/j.cmpb.2026.109361_bib0039","first-page":"e1067","article-title":"Subclinical leaflet thickening and stent frame geometry in self-expanding transcatheter heart valves","volume":"13","author":"Fuchs","year":"2017","journal-title":"EuroIntervention J. EuroPCR Collab. Work. Group Intervent. Cardiol. Eur. Soc. Cardiol."},{"key":"10.1016\/j.cmpb.2026.109361_bib0040","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1007\/s10439-007-9411-x","article-title":"Characterization of hemodynamic forces induced by mechanical heart valves: reynolds vs. viscous stresses","volume":"36","author":"Ge","year":"2008","journal-title":"Ann. Biomed. Eng."},{"issue":"2","key":"10.1016\/j.cmpb.2026.109361_bib0041","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.jmbbm.2007.08.001","article-title":"Fatigue and durability of Nitinol stents","volume":"1","author":"Pelton","year":"2008","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"10.1016\/j.cmpb.2026.109361_bib0042","doi-asserted-by":"crossref","DOI":"10.1016\/j.jmps.2020.104057","article-title":"The influence of mean strain on the high-cycle fatigue of Nitinol with application to medical devices","volume":"143","author":"Cao","year":"2020","journal-title":"J. Mech. Phys. Solids"},{"issue":"3","key":"10.1016\/j.cmpb.2026.109361_bib0043","doi-asserted-by":"crossref","DOI":"10.1002\/cnm.2798","article-title":"Computational comparison of regional stress and deformation characteristics in tricuspid and bicuspid aortic valve leaflets","volume":"33","author":"Cao","year":"2017","journal-title":"Int. J. Numer. Method. Biomed. Eng."},{"issue":"3","key":"10.1016\/j.cmpb.2026.109361_bib0044","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1007\/s13239-018-0366-x","article-title":"Impact of clinically relevant elliptical deformations on the damage patterns of sagging and stretched leaflets in a bioprosthetic heart valve","volume":"9","author":"Sritharan","year":"2018","journal-title":"Cardiovasc. Eng. Technol."},{"issue":"4","key":"10.1016\/j.cmpb.2026.109361_bib0045","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1007\/s13239-016-0285-7","article-title":"Fluid\u2013Structure interaction study of transcatheter aortic valve dynamics using smoothed particle hydrodynamics","volume":"7","author":"Mao","year":"2016","journal-title":"Cardiovasc. Eng. Technol."},{"issue":"9","key":"10.1016\/j.cmpb.2026.109361_bib0046","doi-asserted-by":"crossref","first-page":"2231","DOI":"10.1007\/s10439-015-1260-4","article-title":"Coronary flow impacts aortic leaflet mechanics and aortic sinus hemodynamics","volume":"43","author":"Moore","year":"2015","journal-title":"Ann. Biomed. Eng."},{"key":"10.1016\/j.cmpb.2026.109361_bib0047","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbiomech.2025.112731","article-title":"Can the pinwheeling index serve as a surrogate for accelerated leaflet degeneration in transcatheter heart valves?","author":"Qiu","year":"2025","journal-title":"J. Biomech."},{"issue":"11","key":"10.1016\/j.cmpb.2026.109361_bib0048","first-page":"1113","article-title":"Long-term follow-up of hypoattenuated leaflet thickening after transcatheter aortic valve replacement","volume":"15","author":"Hein","year":"2022","journal-title":"Cardiovas. Interven."},{"issue":"6","key":"10.1016\/j.cmpb.2026.109361_bib0049","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1161\/CIRCULATIONAHA.121.058339","article-title":"Deformation of transcatheter aortic valve prostheses: implications for hypoattenuating leaflet thickening and clinical outcomes","volume":"146","author":"Fukui","year":"2022","journal-title":"Circulation"},{"issue":"17","key":"10.1016\/j.cmpb.2026.109361_bib0050","first-page":"2023","article-title":"Impact of balloon-expandable TAVR valve deformation and calcium distribution on outcomes in bicuspid aortic valve","volume":"17","author":"Nagasaka","year":"2024","journal-title":"Cardiovas. Interven."},{"issue":"9","key":"10.1016\/j.cmpb.2026.109361_bib0051","doi-asserted-by":"crossref","first-page":"6017","DOI":"10.1007\/s00330-022-08747-x","article-title":"Computed tomography predictors of structural valve degeneration in patients undergoing transcatheter aortic valve implantation with balloon-expandable prostheses","volume":"32","author":"Guglielmo","year":"2022","journal-title":"Eur. Radiol."},{"key":"10.1016\/j.cmpb.2026.109361_bib0052","doi-asserted-by":"crossref","first-page":"E141","DOI":"10.1111\/aor.13107","article-title":"Simulated transcatheter aortic valve flow: implications of elliptical deployment and under-expansion at the aortic annulus","volume":"42","author":"Sirois","year":"2018","journal-title":"Artif. Organs"},{"issue":"4","key":"10.1016\/j.cmpb.2026.109361_bib0053","doi-asserted-by":"crossref","DOI":"10.1002\/cnm.70038","article-title":"A neural network finite element trileaflet heart valve model incorporating multi-body contact","volume":"41","author":"Meyer","year":"2025","journal-title":"Int. J. Numer. Method. Biomed. Eng."},{"issue":"5","key":"10.1016\/j.cmpb.2026.109361_bib0054","first-page":"1009","article-title":"Transcatheter aortic valve deployment influences neo-sinus thrombosis risk: an in vitro flow study","volume":"95","author":"Madukauwa-David","year":"2020","journal-title":"Catheter. Cardiovas. Interven."},{"issue":"1","key":"10.1016\/j.cmpb.2026.109361_bib0055","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.jcmg.2018.06.028","article-title":"Transcatheter aortic heart valves: histological analysis providing insight to leaflet thickening and structural valve degeneration","volume":"12","author":"Sellers","year":"2019","journal-title":"JACC Cardiovas. Imag."},{"key":"10.1016\/j.cmpb.2026.109361_bib0056","article-title":"Proteolytic degradation is a major contributor to bioprosthetic heart valve failure","volume":"11","author":"Kostyunin","year":"2022","journal-title":"J. Am. Heart Assoc."},{"issue":"3","key":"10.1016\/j.cmpb.2026.109361_bib0057","first-page":"E411","article-title":"Bioprosthetic valve oversizing is associated with increased risk of valve thrombosis following TAVR","volume":"97","author":"Simpson","year":"2021","journal-title":"Catheter. Cardiovas. Interven."},{"issue":"2","key":"10.1016\/j.cmpb.2026.109361_bib0058","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.jcct.2021.11.013","article-title":"The impact of hypo-attenuated leaflet thickening on haemodynamic valve deterioration following transcatheter aortic valve replacement","volume":"16","author":"Rashid","year":"2022","journal-title":"J. Cardiovasc. Comput. Tomogr."},{"key":"10.1016\/j.cmpb.2026.109361_bib0059","doi-asserted-by":"crossref","DOI":"10.1016\/j.jacc.2025.05.011","article-title":"Valve under-expansion and clinical outcomes with ACURATE neo2: findings from the ACURATE IDE trial","author":"Makkar","year":"2025","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.cmpb.2026.109361_bib0060","doi-asserted-by":"crossref","DOI":"10.1016\/S0140-6736(25)00319-8","article-title":"ACURATE neo2 valve versus commercially available transcatheter heart valves in patients with severe aortic stenosis (ACURATE IDE): a multicentre, randomised, controlled, non-inferiority trial","author":"Makkar","year":"2025","journal-title":"The Lancet"},{"issue":"8","key":"10.1016\/j.cmpb.2026.109361_bib0061","first-page":"1028","article-title":"Clinical impact of midframe underexpansion following TAVR using a self-expanding transcatheter heart valve","volume":"18","author":"Kim","year":"2025","journal-title":"Cardiovas. Interven."},{"issue":"2","key":"10.1016\/j.cmpb.2026.109361_bib0062","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1001\/jamacardio.2022.4627","article-title":"Structural valve deterioration after self-expanding transcatheter or surgical aortic valve implantation in patients at intermediate or high risk","volume":"8","author":"O\u2019Hair","year":"2023","journal-title":"JAMA Cardiol."}],"container-title":["Computer Methods and Programs in Biomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0169260726001264?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0169260726001264?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T13:31:58Z","timestamp":1779456718000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0169260726001264"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":62,"alternative-id":["S0169260726001264"],"URL":"https:\/\/doi.org\/10.1016\/j.cmpb.2026.109361","relation":{},"ISSN":["0169-2607"],"issn-type":[{"value":"0169-2607","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"In silico modeling of transcatheter heart valve oversizing and ellipticity, Part II: Effects on leaflet mechanics, hemodynamics, and stent deflection contributing to thrombogenic risk and structural degeneration","name":"articletitle","label":"Article Title"},{"value":"Computer Methods and Programs in Biomedicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cmpb.2026.109361","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"109361"}}