{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T06:15:33Z","timestamp":1789884933953,"version":"4.0.1"},"reference-count":50,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Colloids and Surfaces B: Biointerfaces"],"published-print":{"date-parts":[[2013,2]]},"DOI":"10.1016\/j.colsurfb.2012.09.026","type":"journal-article","created":{"date-parts":[[2012,9,26]],"date-time":"2012-09-26T07:21:52Z","timestamp":1348644112000},"page":"492-503","source":"Crossref","is-referenced-by-count":25,"special_numbering":"C","title":["On designing stable magnetic vectors as carriers for malaria DNA vaccine"],"prefix":"10.1016","volume":"102","author":[{"given":"Fatin Nawwab","family":"Al-Deen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cordelia","family":"Selomulya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim","family":"Williams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.colsurfb.2012.09.026_bib0005","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1038\/nature03342","article-title":"The global distribution of clinical episodes of Plasmodium falciparum malaria","volume":"434","author":"Snow","year":"2005","journal-title":"Nature"},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0010","first-page":"41","article-title":"DNA vaccination: an immunological perspective","volume":"23","author":"Moreno","year":"2004","journal-title":"Immunology"},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0015","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1016\/S0020-7519(01)00184-9","article-title":"DNA-based vaccines against malaria: status and promise of the multi-stage malaria DNA vaccine operation","volume":"31","author":"Doolan","year":"2001","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0020","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1038\/sj.gt.3302720","article-title":"Gene therapy progress and prospects: magnetic nanoparticle-based gene delivery","volume":"13","author":"Dobson","year":"2006","journal-title":"Gene Ther."},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0025","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1021\/la104278m","article-title":"Stabilization of magnetic iron oxide nanoparticles in biological media by fetal bovine serum (FBS)","volume":"27","author":"Wiogo","year":"2011","journal-title":"Langmuir"},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0030","doi-asserted-by":"crossref","first-page":"3995","DOI":"10.1016\/j.biomaterials.2004.10.012","article-title":"Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications","volume":"26","author":"Gupta","year":"2005","journal-title":"Biomaterials"},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0035","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1038\/nmat2442","article-title":"Understanding biophysicochemical interactions at the nano-bio interface","volume":"8","author":"Nel","year":"2009","journal-title":"Nat. Mater."},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0040","doi-asserted-by":"crossref","first-page":"2521","DOI":"10.1021\/bm100748p","article-title":"Polyethylenimine based magnetic iron-oxide vector: the effect of vector component assembly on cellular entry mechanism, intracellular localization, and cellular viability","volume":"11","author":"Arsianti","year":"2010","journal-title":"Biomacromolecules"},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0045","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1007\/s11671-008-9174-9","article-title":"Magnetic iron oxide nanoparticles: synthesis and surface functionalization strategies","volume":"3","author":"Wu","year":"2008","journal-title":"Nanoscale Res. Lett."},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0050","doi-asserted-by":"crossref","first-page":"7297","DOI":"10.1073\/pnas.92.16.7297","article-title":"A versatile vector for gene and oligonucleotide transfer into cells and in vivo-polyethylenimine","volume":"92","author":"Boussif","year":"1995","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0055","doi-asserted-by":"crossref","first-page":"34","DOI":"10.2533\/chimia.1997.34","article-title":"The proton sponge: a trick to enter cells the viruses did not exploit","volume":"51","author":"Behr","year":"1997","journal-title":"Chimia"},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0060","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1002\/jgm.773","article-title":"Recent advances in rational gene transfer vector design based on poly(ethylene imine) and its derivatives","volume":"7","author":"Neu","year":"2005","journal-title":"J. Gene Med."},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0065","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S0168-3659(99)00090-5","article-title":"Poly(ethylenimine) and its role in gene delivery","volume":"60","author":"Godbey","year":"1999","journal-title":"J. Control. Release"},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0070","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1163\/15685620360674227","article-title":"Novel poly(ethylene glycol) derivatives with carboxylic acid pendant groups: synthesis and their protection and enhancing effect on non-viral gene transfection systems","volume":"14","author":"Koyama","year":"2003","journal-title":"J. Biomater. Sci. Polym. Ed."},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0075","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1002\/jgm.507","article-title":"Gene transfer with modified polyethylenimines","volume":"6","author":"Kichler","year":"2004","journal-title":"J. Gene Med."},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0080","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1080\/10611860802472461","article-title":"Cationic derivatives of biocompatible hyaluronic acids for delivery of siRNA and antisense oligonucleotides","volume":"17","author":"Han","year":"2009","journal-title":"J. Drug Target."},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0085","doi-asserted-by":"crossref","first-page":"9357","DOI":"10.1016\/j.biomaterials.2010.08.043","article-title":"Amphoteric hyaluronic acid derivative for targeting gene delivery","volume":"31","author":"Yao","year":"2010","journal-title":"Biomaterials"},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0090","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1021\/mp800176t","article-title":"Target specific intracellular delivery of siRNA\/PEI-HA complex by receptor mediated endocytosis","volume":"6","author":"Jiang","year":"2009","journal-title":"Mol. Pharm."},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0095","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/j.jconrel.2006.03.013","article-title":"Hyaluronic acid and its derivative as a multi-functional gene expression enhancer: protection from non-specific interactions, adhesion to targeted cells, and transcriptional activation","volume":"112","author":"Ito","year":"2006","journal-title":"J. Control. Release"},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0100","doi-asserted-by":"crossref","first-page":"4981","DOI":"10.1002\/j.1460-2075.1996.tb00878.x","article-title":"HMG1 interacts with HOX proteins and enhances their DNA binding and transcriptional activation","volume":"15","author":"Zappavigna","year":"1996","journal-title":"EMBO J."},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0105","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1080\/10611860801900728","article-title":"Efficient in vivo gene transfection by stable DNA\/PEI complexes coated by hyaluronic acid","volume":"16","author":"Ito","year":"2008","journal-title":"J. Drug Target."},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0110","doi-asserted-by":"crossref","first-page":"3703","DOI":"10.1021\/la104479c","article-title":"Superparamagnetic nanoparticles for effective delivery of malaria DNA vaccine","volume":"27","author":"Al-Deen","year":"2011","journal-title":"Langmuir"},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0115","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1093\/nar\/29.7.1539","article-title":"Trends in lipoplex physical properties dependent on cationic lipid structure, vehicle and complexation procedure do not correlate with biological activity","volume":"29","author":"Ferrari","year":"2001","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0120","doi-asserted-by":"crossref","first-page":"7314","DOI":"10.1021\/la9041919","article-title":"Assembly of polyethylenimine-based magnetic iron oxide vectors: insights into gene delivery","volume":"26","author":"Arsianti","year":"2010","journal-title":"Langmuir"},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0125","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.jconrel.2006.09.006","article-title":"Disassembly of polyethylenimine\u2013DNA particles in vitro: implications for polyethylenimine-mediated DNA delivery","volume":"116","author":"Bertschinger","year":"2006","journal-title":"J. Control. Release"},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0130","series-title":"Polymer Microscopy","author":"Sawyer","year":"2008"},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0135","doi-asserted-by":"crossref","first-page":"2754","DOI":"10.1016\/j.bpj.2011.04.045","article-title":"Molecular dynamics simulations of DNA\/PEI complexes: effect of PEI branching and protonation state","volume":"100","author":"Sun","year":"2011","journal-title":"Biophys. J."},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0140","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1080\/10717540590952555","article-title":"Pharmaceutical characterization and drug delivery","volume":"12","author":"Liao","year":"2005","journal-title":"Drug Deliv."},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0145","doi-asserted-by":"crossref","first-page":"397","DOI":"10.17221\/1930-VETMED","article-title":"Hyaluronic acid (hyaluronan): a review","volume":"53","author":"Necas","year":"2008","journal-title":"Vet. Med. (Praha)"},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0150","doi-asserted-by":"crossref","first-page":"5781","DOI":"10.1063\/1.470459","article-title":"Precipitation of highly-charged polyelectrolyte solutions in presence of multivalent salts","volume":"103","author":"Delacruz","year":"1995","journal-title":"J. Chem. Phys."},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0155","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1002\/pi.4980040307","article-title":"Principles of action of polymeric flocculants","volume":"4","author":"Kitchener","year":"1972","journal-title":"Br. Polym. J."},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0160","doi-asserted-by":"crossref","DOI":"10.1088\/0022-3727\/43\/40\/405002","article-title":"Quantification of the aggregation of magnetic nanoparticles with different polymeric coatings in cell culture medium","volume":"43","author":"Eberbeck","year":"2010","journal-title":"J. Phys. D: Appl. Phys."},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0165","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1002\/(SICI)1097-0282(199907)50:1<23::AID-BIP3>3.0.CO;2-G","article-title":"Effects of sodium chloride, guanidine hydrochloride, and sucrose on the viscoelastic properties of sodium hyaluronate solutions","volume":"50","author":"Mo","year":"1999","journal-title":"Biopolymers"},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0170","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.ijpharm.2010.12.046","article-title":"Novel magnetic iron oxide nanoparticles coated with poly(ethylene imine)-g-poly(ethylene glycol) for potential biomedical application: synthesis, stability, cytotoxicity and MR imaging","volume":"408","author":"Schweiger","year":"2011","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0175","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1080\/10717540903059549","article-title":"Positive hyaluronan\/PEI\/DNA complexes as a target-specific intracellular delivery to malignant breast cancer","volume":"16","author":"Sun","year":"2009","journal-title":"Drug Delivery"},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0180","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.ejpb.2007.02.024","article-title":"Effect of cell media on polymer coated superparamagnetic iron oxide nanoparticles (SPIONs): colloidal stability, cytotoxicity, and cellular uptake studies","volume":"68","author":"Petri-Fink","year":"2008","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0185","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/S0005-2736(98)00199-0","article-title":"Interactions of polymeric and liposomal gene delivery systems with extracellular glycosaminoglycans: physicochemical and transfection studies","volume":"1415","author":"Ruponen","year":"1999","journal-title":"Biochim. Biophys. Acta: Biomembr."},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0190","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/S0168-3659(03)00196-2","article-title":"Release phenomena of insulin from an implantable device composed of a polyion complex of chitosan and sodium hyaluronate","volume":"90","author":"Surini","year":"2003","journal-title":"J. Control. Release"},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0195","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1002\/bit.20161","article-title":"Serum-free large-scale transient transfection of CHO cells","volume":"87","author":"Derouazi","year":"2004","journal-title":"Biotechnol. Bioeng."},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0200","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.bbagen.2004.10.011","article-title":"Glycosaminoglycan destabilization of DNA\u2013chitosan polyplexes for gene delivery depends on chitosan chain length and GAG properties","volume":"1721","author":"Danielsen","year":"2005","journal-title":"Biochim. Biophys. Acta: Gen. Sub."},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0205","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0304-4165(02)00442-7","article-title":"Structural changes in DNA mediated by cationic lipids alter in vitro transcriptional activity at low charge ratios","volume":"1619","author":"Prasad","year":"2003","journal-title":"Biochim. Biophys. Acta: Gen. Sub."},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0210","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/S0169-409X(01)00202-2","article-title":"Design and gene delivery activity of modified polyethylenimines","volume":"53","author":"Kircheis","year":"2001","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0215","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1042\/bj20031230","article-title":"Intracellular proteoglycans","volume":"379","author":"Kolset","year":"2004","journal-title":"Biochem. J."},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0220","article-title":"Structures and functions of proteoglycans","volume":"241","author":"Kuberan","year":"2011","journal-title":"Abstr. Pap. Am. Chem. Soc."},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0225","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0168-3659(01)00415-1","article-title":"Stability of PEI\u2013DNA and DOTAP\u2013DNA complexes: effect of alkaline pH, heparin and serum","volume":"76","author":"Moret","year":"2001","journal-title":"J. Control. Release"},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0230","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.jconrel.2003.08.004","article-title":"Extracellular and intracellular barriers in non-viral gene delivery","volume":"93","author":"Ruponen","year":"2003","journal-title":"J. Control. Release"},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0235","doi-asserted-by":"crossref","first-page":"33875","DOI":"10.1074\/jbc.M011553200","article-title":"Extracellular glycosaminoglycans modify cellular trafficking of lipoplexes and polyplexes","volume":"276","author":"Ruponen","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0240","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1002\/jgm.1125","article-title":"Low molecular weight hyaluronan shielding of DNA\/PEI polyplexes facilitates CD44 receptor mediated uptake in human corneal epithelial cells","volume":"10","author":"Hornof","year":"2008","journal-title":"J. Gene Med."},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0245","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S0168-3659(02)00371-1","article-title":"Loading of plasmid DNA into PLGA microparticles using TROMS (total recirculation one-machine system): evaluation of its integrity and controlled release properties","volume":"86","author":"del Barrio","year":"2003","journal-title":"J. Control. Release"},{"key":"10.1016\/j.colsurfb.2012.09.026_bib0250","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/0092-8674(86)90865-2","article-title":"Expression of transfected DNA depends on DNA topology","volume":"46","author":"Weintraub","year":"1986","journal-title":"Cell"}],"container-title":["Colloids and Surfaces B: Biointerfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0927776512005383?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0927776512005383?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,6,25]],"date-time":"2023-06-25T23:24:12Z","timestamp":1687735452000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0927776512005383"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2]]},"references-count":50,"alternative-id":["S0927776512005383"],"URL":"https:\/\/doi.org\/10.1016\/j.colsurfb.2012.09.026","relation":{},"ISSN":["0927-7765"],"issn-type":[{"value":"0927-7765","type":"print"}],"subject":[],"published":{"date-parts":[[2013,2]]}}}