{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T10:33:11Z","timestamp":1789381991757,"version":"build-2803163510"},"reference-count":64,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Colloids and Surfaces B: Biointerfaces"],"published-print":{"date-parts":[[2015,9]]},"DOI":"10.1016\/j.colsurfb.2015.05.041","type":"journal-article","created":{"date-parts":[[2015,5,29]],"date-time":"2015-05-29T20:16:51Z","timestamp":1432930611000},"page":"1-11","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":52,"special_numbering":"C","title":["Investigation on cellular interactions of astrocytes with zinc oxide nanoparticles using rat C6 cell lines"],"prefix":"10.1016","volume":"133","author":[{"given":"S.","family":"Sruthi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.V.","family":"Mohanan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.colsurfb.2015.05.041_bib0325","doi-asserted-by":"crossref","first-page":"M46","DOI":"10.1111\/j.1750-3841.2008.01013.x","article-title":"Antimicrobial efficacy of zinc oxide quantum dots against Listeria monocytogenes, Salmonella Enteritidis, and Escherichia coli O157:H7","volume":"74","author":"Jin","year":"2009","journal-title":"J. Food Sci."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0330","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1088\/1468-6996\/9\/3\/035004","article-title":"Enhanced bioactivity of ZnO nanoparticles \u2013 an antimicrobial study","volume":"9","author":"Padmavathy","year":"2008","journal-title":"Sci. Technol. Adv. Mater."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0335","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1111\/j.1574-6968.1985.tb00864.x","article-title":"Photo-electroehemical sterilisation of microbial cells by semiconductor powders","volume":"29","author":"Matsunaga","year":"1985","journal-title":"FEMS Microbiol. Lett."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0340","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1166\/jnn.2010.2044","article-title":"Hybrid zinc oxide nanoparticles for biophotonics","volume":"10","author":"John","year":"2010","journal-title":"J. Nanosci. Nanotechnol."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0345","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1088\/0957-4484\/19\/29\/295103","article-title":"Preferential killing of cancer cells and activated human T cells using zinc oxide nanoparticles","volume":"19","author":"Hanley","year":"2008","journal-title":"Nanotechnology"},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0350","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1517\/17425247.2010.502560","article-title":"Zinc oxide nanoparticles for selective destruction of tumor cells and potential for drug delivery applications","volume":"7","author":"Rasmussen","year":"2010","journal-title":"Expert Opin. Drug Deliv."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0355","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1002\/smll.200500193","article-title":"Three-dimensional functionalized tetrapod-like ZnO nanostructures for plasmid DNA delivery","volume":"2","author":"Nie","year":"2006","journal-title":"Small"},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0360","doi-asserted-by":"crossref","first-page":"3087","DOI":"10.1016\/j.biomaterials.2010.01.007","article-title":"ZnO QD@PMAA-co-PDMAEMA nonviral vector for plasmid DNA delivery and bioimaging","volume":"31","author":"Zhang","year":"2010","journal-title":"Biomaterials"},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0365","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1038\/cgt.2008.97","article-title":"Nanoparticle delivery of anti-metastatic NM23 H1 gene improves chemotherapy in a mouse tumor model","volume":"16","author":"Li","year":"2009","journal-title":"Cancer Gene Ther."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0370","doi-asserted-by":"crossref","first-page":"2732","DOI":"10.1016\/j.actbio.2010.01.025","article-title":"New generation of chitosan-encapsulated ZnO quantum dots loaded with drug: synthesis, characterization and in vitro drug delivery response","volume":"6","author":"Yuan","year":"2010","journal-title":"Acta Biomater."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0375","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/s10856-008-3541-z","article-title":"Fluorescent dye encapsulated ZnO particles with cell specific toxicity for potential use in biomedical applications","volume":"20","author":"Wang","year":"2009","journal-title":"J. Mater. Sci. Mater. Med."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0380","doi-asserted-by":"crossref","first-page":"0949071","DOI":"10.1063\/1.3009317","article-title":"Zinc oxide nanoparticles as novel alpha-amylase inhibitors","volume":"104","author":"Dhobale","year":"2008","journal-title":"J. Appl. Phys."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0385","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1007\/s10534-009-9254-z","article-title":"Comparison of inhibitory activities of zinc oxide ultrafine and fine particulates on IgE-induced mast cell activation","volume":"22","author":"Yamaki","year":"2009","journal-title":"Biometals"},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0390","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1039\/b502142c","article-title":"Size matters: why nanomaterials are different","volume":"35","author":"Roduner","year":"2006","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0395","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1039\/b9pp00180h","article-title":"Human safety review of \u201cnano\u201d titanium dioxide and zinc oxide","volume":"9","author":"Schilling","year":"2010","journal-title":"Photochem. Photobiol. Sci."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0400","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1126\/science.1114397","article-title":"Toxic potential of materials at the nanolevel","volume":"311","author":"Nel","year":"2006","journal-title":"Science"},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0405","doi-asserted-by":"crossref","first-page":"7329","DOI":"10.1021\/es100247x","article-title":"Impacts of metal oxide nanoparticles on marine phytoplankton","volume":"44","author":"Miller","year":"2003","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0410","doi-asserted-by":"crossref","first-page":"8484","DOI":"10.1021\/es071445r","article-title":"Comparative toxicity of nanoparticulate ZnO, bulk ZnO, and ZnCl2 to a freshwater microalga (Pseudokirchneriella subcapitata): the importance of particle solubility","volume":"41","author":"Franklin","year":"2007","journal-title":"Environ. Sci."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0415","doi-asserted-by":"crossref","first-page":"1516","DOI":"10.1016\/j.biortech.2010.07.117","article-title":"Interaction and nanotoxic effect of ZnO and Ag nanoparticles on mesophilic and halophilic bacterial cells","volume":"102","author":"Sinha","year":"2010","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0420","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1016\/j.tiv.2009.05.015","article-title":"Toxicity of nanoparticles of ZnO, CuO and TiO2 to yeast Saccharomyces cerevisiae","volume":"23","author":"Kasemets","year":"2009","journal-title":"Toxicol. In Vitro"},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0425","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.tox.2009.07.007","article-title":"Toxicity of ZnO and CuO nanoparticles to ciliated protozoa Tetrahymena thermophila","volume":"269","author":"Mortimer","year":"2010","journal-title":"Toxicology"},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0430","doi-asserted-by":"crossref","first-page":"1975","DOI":"10.1039\/c1em10197h","article-title":"Comparative toxicity of nano-ZnO and bulk ZnO suspensions to zebrafish and the effects of sedimentation, OH production and particle dissolution in distilled water","volume":"13","author":"Yu","year":"2011","journal-title":"J. Environ. Monit."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0435","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1007\/s11051-007-9245-3","article-title":"Acute toxicological impact of nano- and submicro-scaled zinc oxide powder on healthy adult mice","volume":"10","author":"Wang","year":"2008","journal-title":"J. Nanopart. Res."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0440","first-page":"235","article-title":"Role of size scale of ZnO nanoparticles and microparticles on toxicity toward bacteria and osteoblast cancer cells","volume":"20","author":"Nair","year":"2008","journal-title":"J. Mater. Sci.: Mater. Med."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0445","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1007\/s11671-009-9413-8","article-title":"The influences of cell type and ZnO nanoparticle size on immune cell cytotoxicity and cytokine induction","volume":"4","author":"Hanley","year":"2009","journal-title":"Nanoscale Res. Lett."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0450","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1002\/jat.1385","article-title":"Comparative study of cytotoxicity, oxidative stress and genotoxicity induced by four typical nanomaterials: the role of particle size, shape and composition","volume":"29","author":"Yang","year":"2008","journal-title":"J. Appl. Toxicol."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0455","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.taap.2010.04.012","article-title":"Exposure to ZnO nanoparticles induces oxidative stress and cytotoxicity in human colon carcinoma cells","volume":"246","author":"Berardis","year":"2010","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0460","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1002\/jat.1385","article-title":"Comparative study of cytotoxicity, oxidative stress and genotoxicity induced by four typical nanomaterials: the role of particle size, shape and composition","volume":"29","author":"Yang","year":"2009","journal-title":"J. Appl. Toxicol."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0465","doi-asserted-by":"crossref","first-page":"1794","DOI":"10.1021\/nl061025k","article-title":"Comparison of the abilities of ambient and manufactured nanoparticles to induce cellular toxicity according to an oxidative stress paradigm","volume":"6","author":"Xia","year":"2006","journal-title":"Nano Lett."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0470","doi-asserted-by":"crossref","first-page":"2699","DOI":"10.1080\/10934520600966177","article-title":"Toxicity of metal oxide nanoparticles in mammalian cells","volume":"41","author":"Jeng","year":"2006","journal-title":"J. Environ. Sci. Health A Tox. Hazard Subst. Environ. Eng."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0475","doi-asserted-by":"crossref","first-page":"15399","DOI":"10.1021\/la101033n","article-title":"Effects of surface chemistry on cytotoxicity, genotoxicity, and the generation of reactive oxygen species induced by ZnO nanoparticles","volume":"26","author":"Yin","year":"2010","journal-title":"Langmuir"},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0480","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1021\/nn901503q","article-title":"Use of a rapid cytotoxicity screening approach to engineer a safer zinc oxide nanoparticle through iron doping","volume":"4","author":"George","year":"2009","journal-title":"ACS Nano"},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0485","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.toxlet.2010.10.003","article-title":"Role of the dissolved zinc ion and reactive oxygen species in cytotoxicity of ZnO nanoparticles","volume":"199","author":"Song","year":"2010","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0490","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1006\/taap.1999.8639","article-title":"Transport of manganese via the olfactory pathway in rats: dosage dependency of the uptake and subcellular distribution of the metal in the olfactory epithelium and the brain","volume":"156","author":"Henriksson","year":"1999","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0495","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1080\/08958370490439597","article-title":"Translocation of inhaled ultrafine particles to the brain","volume":"16","author":"Oberdorster","year":"2004","journal-title":"Inhal. Toxicol."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0500","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1289\/ehp.7339","article-title":"Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles","volume":"113","author":"Oberdorster","year":"2005","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0505","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1289\/ehp.9030","article-title":"Translocation of inhaled ultrafine manganese oxide particles to the central nervous system","volume":"114","author":"Elder","year":"2006","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0510","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1146\/annurev.neuro.21.1.347","article-title":"Zinc and brain injury","volume":"21","author":"Choi","year":"1998","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0515","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1007\/s12031-012-9756-y","article-title":"Demonstration of an olfactory bulb\u2013brain translocation pathway for ZnO nanoparticles in rodent cells in vitro and in vivo","volume":"48","author":"Kao","year":"2012","journal-title":"J. Mol. Neurosci."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0520","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1093\/toxsci\/kfr319","article-title":"Zinc oxide nanoparticles interfere with zinc ion homeostasis to cause cytotoxicity","volume":"125","author":"Kao","year":"2012","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0525","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.neuro.2008.12.005","article-title":"Influences of nanoparticles zinc oxide on acutely isolated rat hippocampal CA3 pyramidal neurons","volume":"30","author":"Zhao","year":"2009","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0530","doi-asserted-by":"crossref","first-page":"115101","DOI":"10.1088\/0957-4484\/20\/11\/115101","article-title":"Nanosized zinc oxide particles induce neural stem cell apoptosis","volume":"20","author":"Deng","year":"2009","journal-title":"Nanotechnology"},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0535","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1016\/j.biocel.2004.10.004","article-title":"Astrocytes: regulation of brain homeostasis via apolipoprotein E","volume":"37","author":"Gee","year":"2005","journal-title":"Int. J. Biochem. Cell B"},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0540","first-page":"1","article-title":"Zinc oxide nanoparticles induced oxidative stress in mouse bone marrow mesenchymal stem cells","volume":"3","author":"Syama","year":"2014","journal-title":"Toxicol. Mech. Methods"},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0545","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0022-1759(83)90303-4","article-title":"Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays","volume":"65","author":"Mosmann","year":"1983","journal-title":"J. Immunol. Methods"},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0550","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/0378-4274(85)90046-3","article-title":"Toxicity determined in vitro by morphological alterations and neutral red absorption","volume":"24","author":"Borenfreund","year":"1985","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0555","doi-asserted-by":"crossref","first-page":"3018","DOI":"10.1021\/es0625632","article-title":"Simple and easy method to evaluate uptake potential of nanoparticles in mammalian cells using a flow cytometric light scatter analysis","volume":"41","author":"Suzuki","year":"2007","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0560","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/0022-1759(93)90150-6","article-title":"An automated microfluorometric assay for monitoring oxidative burst activity of phagocytes","volume":"159","author":"Wan","year":"1993","journal-title":"J. Immunol. Methods"},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0565","doi-asserted-by":"crossref","first-page":"4996","DOI":"10.1166\/jnn.2009.GR02","article-title":"Nanoparticles and the brain: cause for concern?","volume":"9","author":"Oberd\u00f6rster","year":"2009","journal-title":"J. Nanosci. Nanotechnol."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0570","doi-asserted-by":"crossref","first-page":"149","DOI":"10.2217\/fnl.12.90","article-title":"Astroglia in neurological diseases","volume":"8","author":"Verkhratsky","year":"2013","journal-title":"Future Neurol."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0575","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1007\/s00216-010-3996-x","article-title":"Toxicity assessment of nanomaterials: methods and challenges","volume":"398","author":"Dhawan","year":"2010","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0580","first-page":"845","article-title":"Zinc oxide nanoparticles selectively induce apoptosis in human cancer cells through reactive oxygen species","volume":"7","author":"Akhtar","year":"2012","journal-title":"Int. J. Nanomed."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0585","doi-asserted-by":"crossref","first-page":"3657","DOI":"10.1039\/c1nr10272a","article-title":"Rapid dissolution of ZnO nanocrystals in acidic cancer microenvironment leading to preferential apoptosis","volume":"3","author":"Sasidharan","year":"2011","journal-title":"Nanoscale"},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0590","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.tox.2012.09.005","article-title":"Titanium dioxide nanoparticles inhibit proliferation and induce morphological changes and apoptosis in glial cells","volume":"302","author":"M\u00e1rquez-Ram\u00edrez","year":"2012","journal-title":"Toxicology"},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0595","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1021\/tx900203v","article-title":"ZnO particulate matter requires cell contact for toxicity in human colon cancer cells","volume":"23","author":"Moos","year":"2010","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0600","doi-asserted-by":"crossref","first-page":"402","DOI":"10.3109\/17435390.2012.666575","article-title":"In vitro mechanistic study towards a better understanding of ZnO nanoparticle toxicity","volume":"7","author":"Buerki-Thurnherr","year":"2012","journal-title":"Nanotoxicology"},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0605","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1021\/la203542x","article-title":"Dissolution of ZnO nanoparticles at circumneutral pH: a study of size effects in the presence and absence of citric acid","volume":"28","author":"Mudunkotuwa","year":"2012","journal-title":"Langmuir"},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0610","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.toxlet.2010.10.003","article-title":"Role of the dissolved zinc ion and reactive oxygen species in cytotoxicity of ZnO nanoparticles","volume":"199","author":"Songa","year":"2010","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0615","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.tiv.2009.09.007","article-title":"Oxidative stress, calcium homeostasis, and altered gene expression in human lung epithelial cells exposed to ZnO nanoparticles","volume":"24","author":"Huang","year":"2010","journal-title":"Toxicol. In Vitro"},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0620","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.freeradbiomed.2014.04.026","article-title":"Titanium dioxide nanoparticles induce strong oxidative stress and mitochondrial damage in glial cells","volume":"73","author":"Huerta-Garc\u00eda","year":"2014","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0625","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1159\/000017464","article-title":"Microglial cells in culture express a prominent glutathione system for the defense against reactive oxygen species","volume":"22","author":"Hirrlinger","year":"2000","journal-title":"Dev. Neurosci."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0630","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/0006-8993(92)90317-3","article-title":"Mesencephalic type I astrocytes mediate the survival of substantia nigra dopaminergic neurons in culture","volume":"582","author":"O\u2019Malley","year":"1992","journal-title":"Brain Res."},{"issue":"1745","key":"10.1016\/j.colsurfb.2015.05.041_bib0635","article-title":"Gold nanoparticles trigger apoptosis and necrosis in lung cancer cells with low intracellular glutathione","volume":"15","author":"Liu","year":"2013","journal-title":"J. Nanopart. Res."},{"key":"10.1016\/j.colsurfb.2015.05.041_bib0640","doi-asserted-by":"crossref","first-page":"e65704","DOI":"10.1371\/journal.pone.0065704","article-title":"Zinc oxide nanoparticles induce necrosis and apoptosis in macrophages in a p47phox- and Nrf2-independent manner","volume":"8","author":"Wilhelmi","year":"2013","journal-title":"PLOS ONE"}],"container-title":["Colloids and Surfaces B: Biointerfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0927776515003549?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0927776515003549?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,25]],"date-time":"2019-08-25T17:00:18Z","timestamp":1566752418000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0927776515003549"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9]]},"references-count":64,"alternative-id":["S0927776515003549"],"URL":"https:\/\/doi.org\/10.1016\/j.colsurfb.2015.05.041","relation":{},"ISSN":["0927-7765"],"issn-type":[{"value":"0927-7765","type":"print"}],"subject":[],"published":{"date-parts":[[2015,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Investigation on cellular interactions of astrocytes with zinc oxide nanoparticles using rat C6 cell lines","name":"articletitle","label":"Article Title"},{"value":"Colloids and Surfaces B: Biointerfaces","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.colsurfb.2015.05.041","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}