{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T17:09:04Z","timestamp":1776877744806,"version":"3.51.2"},"reference-count":50,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T00:00:00Z","timestamp":1485907200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Colloids and Surfaces B: Biointerfaces"],"published-print":{"date-parts":[[2017,2]]},"DOI":"10.1016\/j.colsurfb.2016.11.013","type":"journal-article","created":{"date-parts":[[2016,11,9]],"date-time":"2016-11-09T16:18:59Z","timestamp":1478708339000},"page":"32-40","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":75,"special_numbering":"C","title":["Nanoencapsulation of coenzyme Q10 and vitamin E acetate protects against UVB radiation-induced skin injury in mice"],"prefix":"10.1016","volume":"150","author":[{"given":"Nath\u00e1li S.","family":"Pegoraro","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allanna V.","family":"Barbieri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camila","family":"Camponogara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juliane","family":"Mattiazzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evelyne S.","family":"Brum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marila C.L.","family":"Marchiori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara M.","family":"Oliveira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Let\u00edcia","family":"Cruz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.colsurfb.2016.11.013_bib0005","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.biocel.2006.07.001","article-title":"Free radicals and antioxidants in normal physiological functions and human disease","volume":"39","author":"Valko","year":"2007","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0010","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.abb.2010.12.023","article-title":"Role of \u03b2-TrCP ubiquitin ligase receptor in UVB mediated responses in skin Arch","volume":"508","author":"Bhatia","year":"2011","journal-title":"Biochem. Biophys."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0015","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.ijpharm.2011.08.018","article-title":"Production and characterization of antioxidant apigenin nanocrystals as a novel UV skin protective formulation","volume":"420","author":"Al Shaal","year":"2011","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0020","first-page":"1","article-title":"Reactive oxygen species: from health to disease","volume":"142","author":"Brieger","year":"2012","journal-title":"Swiss Med. Wkly."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0025","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1016\/j.freeradbiomed.2011.11.002","article-title":"Role of reactive oxygen and nitrogen species in the vascular responses to inflammation","volume":"52","author":"Kvietys","year":"2012","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0030","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.taap.2009.12.001","article-title":"Safety assessment of personal care products\/cosmetics and their ingredients","volume":"242","author":"Nohynek","year":"2010","journal-title":"Toxicol. Appl. Pharm."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0035","first-page":"64","article-title":"Bioactive compounds from natural resources against skin aging","volume":"19","author":"Mukherjee","year":"2011","journal-title":"Int. J. Phytotherapy Phytopharm."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0040","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1016\/j.clindermatol.2013.05.013","article-title":"Anti-aging cosmetics: facts and controversies","volume":"31","author":"Ramos-e-Silva","year":"2013","journal-title":"Clin. Dermatol."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0045","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.nutres.2007.04.011","article-title":"Concentration response to the coenzyme Q10 supplement Q-Gel in human volunteers","volume":"27","author":"Molyneux","year":"2007","journal-title":"Nutr. Res."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0050","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1590\/S1984-82502009000400002","article-title":"Coenzyme Q10 and its effects in the treatment of neurodegenerative diseases","volume":"45","author":"Dos Santos","year":"2009","journal-title":"Braz. J. Pharm. Sci."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0055","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.ijpharm.2010.06.007","article-title":"Influence of nanostructured lipid carriers (NLC) on the physical properties of the Cutanova Nanorepair Q10 cream and the in vivo skin hydration effect","volume":"396","author":"Pardeike","year":"2010","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0060","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.ijpharm.2010.03.032","article-title":"The advantages of a novel CoQ10 delivery system in skin photo-protection","volume":"392","author":"Yue","year":"2010","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0065","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/j.ijpharm.2013.06.075","article-title":"Nanostructured lipid carriers loaded with CoQ10: effect on human dermal fibroblasts under normal and UVA-mediated oxidative conditions","volume":"455","author":"Brug\u00e8","year":"2013","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0070","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.pharmthera.2015.12.003","article-title":"Vitamin E therapy beyond cancer: tocopherol versus tocotrienol","volume":"162","author":"Peh","year":"2016","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0075","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1093\/ajcn\/74.6.714","article-title":"Gamma-tocopherol, the major form of vitamin E in the US diet, deserves more attention","volume":"74","author":"Jiang","year":"2000","journal-title":"Am.J. Clin. Nutr."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0080","first-page":"405","article-title":"Vitamin-based cosmeceuticals","volume":"25","author":"Jacob","year":"2012","journal-title":"J. Cosmet. Dermatol."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0085","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.jphotobiol.2015.09.016","article-title":"In vivo photoprotective effects of cosmetic formulations containing UV filters, vitamins, Ginkgo biloba and red algae extracts","volume":"153","author":"Mercurio","year":"2015","journal-title":"J. Photochem. Photobiol. B"},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0090","doi-asserted-by":"crossref","first-page":"267","DOI":"10.4103\/2229-5178.120635","article-title":"Nanocarriers and nanoparticles for skin care and dermatological tratments","volume":"4","author":"Gupta","year":"2013","journal-title":"Indian Dermatol. Online J."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0095","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/j.technovation.2007.05.009","article-title":"Nanotechnology systems of innovation \u2013 an analysis of industry and academia research activities","volume":"27","author":"Miyazaki","year":"2007","journal-title":"Technovation"},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0100","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1002\/wnan.1334","article-title":"Improving drug biological effects by encapsulation into polymeric nanocapsules","volume":"7","author":"Frank","year":"2015","journal-title":"Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0105","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.ejpb.2011.03.008","article-title":"Improved photostability and reduced skin permeation of tretinoin: development of a semisolid nanomedicine","volume":"79","author":"Ourique","year":"2011","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0110","doi-asserted-by":"crossref","first-page":"E1","DOI":"10.1208\/pt070491","article-title":"Development and evaluation of topical formulation containing solid lipid nanoparticles of vitamin A","volume":"7","author":"Pople","year":"2006","journal-title":"AAPS PharmSciTech."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0115","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.ejpb.2015.03.020","article-title":"Nanoencapsulation of rice bran oil increases its protective effects against UVB-radiation induced skin injury in mice","volume":"93","author":"Rigo","year":"2015","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0120","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.ijpharm.2014.03.038","article-title":"Application of gellan gum in pharmacy and medicine","volume":"466","author":"Osmalek","year":"2014","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0125","doi-asserted-by":"crossref","first-page":"R1","DOI":"10.1016\/0378-5173(89)90281-0","article-title":"Nanocapsule formation by interfacial polymer deposition following solvent displacement","volume":"55","author":"Fessi","year":"1989","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0130","first-page":"347","article-title":"Validation of a RP-HPLC-UV method for the assay of ubiquinone in pracaxi oil-core nanocapsules","volume":"33","author":"Mattiazzi","year":"2014","journal-title":"Lat. Am. J. Pharm."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0135","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1590\/S1516-93322006000400008","article-title":"Desenvolvimento e avalia\u00e7\u00e3o da estabilidade f\u00edsica de lo\u00e7\u00f5es O\/A contendo filtros solares","volume":"42","author":"Borghetti","year":"2006","journal-title":"Rev. Bras. Cienc. Farm."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0140","first-page":"1387","article-title":"Evaluation of the spreadability of pharmaceutical or cosmetic semisolid formulations using scanned images","volume":"31","author":"Rigo","year":"2012","journal-title":"Lat. Am. J. Pharm."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0145","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1007\/s00396-002-0808-7","article-title":"Rheological properties and microstructures of Carbopol gel network system","volume":"281","author":"Kim","year":"2003","journal-title":"Colloid. Polym. Sci."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0150","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/0304-3959(83)90201-4","article-title":"Ethical guidelines for investigations of experimental pain in conscious animals","volume":"16","author":"Zimmermann","year":"1983","journal-title":"Pain"},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0155","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.jphotobiol.2006.01.006","article-title":"Protective effect of topical formulations containing quercetin against UV-B-induced oxidative stress in hairless mice","volume":"84","author":"Casagrande","year":"2006","journal-title":"J. Photochem. Photobiol. B"},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0160","first-page":"274","article-title":"Evaluation of protective effect of a water-in-oil microemulsion incorporating quercetin against UVB-induced damage in hairless mice skin","volume":"13","author":"Vicentini","year":"2010","journal-title":"J. Pharm. Sci"},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0165","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.ejpb.2005.06.002","article-title":"Using cyclodextrin complexation to enhance secondary photoprotection of topically applied ibuprofen","volume":"62","author":"Godwin","year":"2006","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0170","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1016\/j.lfs.2011.03.017","article-title":"The involvement of TRPA1 channel activation in the inflammatory response evoked by topical application of cinnamaldehyde to mice","volume":"88","author":"Silva","year":"2011","journal-title":"Life Sci."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0175","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/j.pbb.2014.07.005","article-title":"Antinociceptive effect of 3-(4-fluorophenyl)-5-trifluoromethyl-1H-1-tosylpyrazole. A Celecoxib structural analog in models of pathological pain","volume":"124","author":"Oliveira","year":"2014","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0180","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.jep.2015.12.036","article-title":"Topical anti-inflammatory activity of Solanum corymbiflorum leaves J","volume":"179","author":"Piana","year":"2016","journal-title":"Ethnopharmacol"},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0185","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/j.jpain.2009.09.016","article-title":"Spinal levels of nonproteinthiols are related to nociception in mice","volume":"11","author":"Rossato","year":"2010","journal-title":"J. Pain"},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0190","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.reprotox.2008.09.009","article-title":"Cadmium induced testicular pathophysiology: prophylactic role of taurine","volume":"26","author":"Manna","year":"2008","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0195","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.jphotobiol.2014.02.019","article-title":"Anti-inflammatory and antioxidant effects of Aloe saponaria Haw in a model of UVB-induced paw sunburn in rats","volume":"133","author":"Silva","year":"2014","journal-title":"J. Photochem. Photobiol. B"},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0200","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1159\/000094670","article-title":"The pH of the skin surface and its impact on the barrier function","volume":"19","author":"Schmid-Wendtner","year":"2006","journal-title":"Skin Pharmacol. Physiol."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0205","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/j.addr.2011.01.012","article-title":"Nanoparticles and microparticles for skin drug delivery","volume":"63","author":"Prow","year":"2011","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0210","first-page":"819","article-title":"Development of semi-Solid cosmetic formulations containing coenzyme Q10-Loaded nanocapsules","volume":"28","author":"Terroso","year":"2009","journal-title":"Lat. Am. J. Pharm."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0215","first-page":"84","article-title":"Spreading of semisolid formulations \u2212 an update","volume":"26","author":"Garg","year":"2002","journal-title":"Pharm. Technol."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0220","series-title":"Non-Newtonian Flow and Applied Rheology","author":"Chhabra","year":"2016"},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0225","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.pain.2006.12.014","article-title":"Characterisation of ultraviolet-B induced inflammation as a model of hyperalgesia in the rat","volume":"13","author":"Bishop","year":"2007","journal-title":"Pain"},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0230","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1016\/j.jep.2009.12.019","article-title":"Protective effect of Calendula officinalis extract against UVB-induced oxidative stress in skin: evaluation of reduced glutathione levels and matrix metalloproteinase secretion","volume":"127","author":"Fonseca","year":"2010","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0235","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.taap.2013.03.015","article-title":"Quercitrin protects skin from UVB-induced oxidative damage","volume":"269","author":"Yin","year":"2013","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0240","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.ejpb.2006.10.019","article-title":"Nanoparticles -an efficient carrier for drug delivery into the hair follicles","volume":"66","author":"Lademann","year":"2007","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0245","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/j.scr.2015.10.008","article-title":"Short-term UVB-irradiation leads to putative limbal stem cell damage and niche cell-mediated upregulation of macrophage recruiting cytokines","volume":"15","author":"Notara","year":"2015","journal-title":"Stem Cell Res."},{"key":"10.1016\/j.colsurfb.2016.11.013_bib0250","doi-asserted-by":"crossref","first-page":"3546","DOI":"10.1073\/pnas.0914351107","article-title":"Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis","volume":"107","author":"Hattori","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U. S. A."}],"container-title":["Colloids and Surfaces B: Biointerfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0927776516307895?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0927776516307895?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,6]],"date-time":"2018-09-06T17:57:04Z","timestamp":1536256624000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0927776516307895"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2]]},"references-count":50,"alternative-id":["S0927776516307895"],"URL":"https:\/\/doi.org\/10.1016\/j.colsurfb.2016.11.013","relation":{},"ISSN":["0927-7765"],"issn-type":[{"value":"0927-7765","type":"print"}],"subject":[],"published":{"date-parts":[[2017,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Nanoencapsulation of coenzyme Q10 and vitamin E acetate protects against UVB radiation-induced skin injury in mice","name":"articletitle","label":"Article Title"},{"value":"Colloids and Surfaces B: Biointerfaces","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.colsurfb.2016.11.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}