{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T17:35:34Z","timestamp":1792690534147,"version":"4.5.0"},"reference-count":67,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004901","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de Minas Gerais","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004901","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Colloids and Surfaces B: Biointerfaces"],"published-print":{"date-parts":[[2020,4]]},"DOI":"10.1016\/j.colsurfb.2019.110749","type":"journal-article","created":{"date-parts":[[2019,12,27]],"date-time":"2019-12-27T11:24:09Z","timestamp":1577445849000},"page":"110749","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":95,"special_numbering":"C","title":["Retinoic acid-loaded solid lipid nanoparticles surrounded by chitosan film support diabetic wound healing in in vivo study"],"prefix":"10.1016","volume":"188","author":[{"given":"Valqu\u00edria T.","family":"Arantes","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9 A.G.","family":"Faraco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederico B.","family":"Ferreira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cleida A.","family":"Oliveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elis\u00e2ngela","family":"Martins-Santos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Puebla","family":"Cassini-Vieira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luc\u00edola S.","family":"Barcelos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas A.M.","family":"Ferreira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0292-076X","authenticated-orcid":false,"given":"Gisele A.C.","family":"Goulart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.colsurfb.2019.110749_bib0005","series-title":"International Diabetes Federation (IDF) Diabetes Atlas","year":"2017"},{"key":"10.1016\/j.colsurfb.2019.110749_bib0010","doi-asserted-by":"crossref","DOI":"10.3390\/ijms18071419","volume":"18","author":"Okonkwo","year":"2017","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0015","doi-asserted-by":"crossref","first-page":"855","DOI":"10.2337\/diabetes.54.3.855","volume":"54","author":"Lateef","year":"2005","journal-title":"Diabetes"},{"key":"10.1016\/j.colsurfb.2019.110749_bib0020","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1111\/j.1365-2133.1995.tb08623.x","volume":"132","author":"Popp","year":"1995","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0025","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1001\/archderm.1989.01670130067008","volume":"125","author":"Hung","year":"1989","journal-title":"Arch. Dermatol."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0030","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1007\/PL00007466","volume":"293","author":"Kitano","year":"2001","journal-title":"Arch. Dermatol. Res."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0035","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1001\/archderm.141.11.1373","volume":"141","author":"Tom","year":"2005","journal-title":"Arch. Dermatol."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0040","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1067\/mjd.2001.116238","volume":"45","author":"Paquette","year":"2001","journal-title":"J. Am. Acad. Dermatol."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0045","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1038\/s41590-018-0230-z","volume":"19","author":"Povoleri","year":"2018","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0050","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1096\/fasebj.10.9.8801161","volume":"10","author":"Fisher","year":"1996","journal-title":"FASEB J."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0055","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/j.diff.2016.05.001","volume":"92","author":"Mammadova","year":"2016","journal-title":"Differentiation"},{"key":"10.1016\/j.colsurfb.2019.110749_bib0060","doi-asserted-by":"crossref","first-page":"283","DOI":"10.3109\/09546634.2012.697985","volume":"24","author":"Gunes","year":"2013","journal-title":"J. Dermatolog. Treat."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0065","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/j.jaad.2004.08.059","volume":"52","author":"Muehlberger","year":"2005","journal-title":"J. Am. Acad. Dermatolol."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0070","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1046\/j.1365-2133.1997.18101910.x","volume":"137","author":"Ale","year":"1997","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0075","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.jdermsci.2014.08.003","volume":"76","author":"Cheong","year":"2014","journal-title":"J. Dermatol. Sci."},{"issue":"6","key":"10.1016\/j.colsurfb.2019.110749_bib0080","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1210\/mend.11.6.0010","volume":"11","author":"Attar","year":"1997","journal-title":"Mol. Endocrinol."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0085","first-page":"1789","volume":"43","author":"Li","year":"2019","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0090","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/0144-8617(94)90115-5","volume":"24","author":"Chen","year":"1994","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0095","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ijpharm.2008.09.047","volume":"368","author":"Rodrigues","year":"2009","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0100","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.ijpharm.2009.07.025","volume":"381","author":"Castro","year":"2009","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0105","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1007\/s00403-011-1130-3","volume":"303","author":"Castro","year":"2011","journal-title":"Arch. Dermatol. Res."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0110","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1080\/02652040010018056","volume":"19","author":"Dingler","year":"2002","journal-title":"J. Microencapsul."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0115","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S0939-6411(00)00087-4","volume":"50","author":"M\u00fcller","year":"2000","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0120","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S0928-0987(01)00095-1","volume":"13","author":"Costa","year":"2001","journal-title":"Eur. J. Pharm. Sci."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0125","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/0168-3659(87)90034-4","volume":"5","author":"Ritger","year":"1987","journal-title":"J. Control. Release"},{"key":"10.1016\/j.colsurfb.2019.110749_bib0130","doi-asserted-by":"crossref","first-page":"261","DOI":"10.2340\/00015555-1531","volume":"93","author":"Ali","year":"2013","journal-title":"Acta Derm. Venereol."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0135","doi-asserted-by":"crossref","first-page":"217","DOI":"10.2165\/00128071-200405040-00002","volume":"5","author":"Rippke","year":"2004","journal-title":"Am. J. Clin. Dermatol."},{"issue":"5.47","key":"10.1016\/j.colsurfb.2019.110749_bib0140","first-page":"1","volume":"70","author":"Furman","year":"2015","journal-title":"Curr. Protoc. Pharmacol."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0145","author":"Wu","year":"2008","journal-title":"Curr. Protoc. Pharmacol."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0150","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1161\/CIRCRESAHA.108.192138","volume":"104","author":"Barcelos","year":"2009","journal-title":"Circ. Res."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0155","doi-asserted-by":"crossref","first-page":"5171","DOI":"10.4049\/jimmunol.1400625","volume":"193","author":"Canesso","year":"2014","journal-title":"J. Immunol."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0160","volume":"5","author":"Moreira","year":"2015","journal-title":"Bioprotocol"},{"key":"10.1016\/j.colsurfb.2019.110749_bib0165","volume":"5","author":"Cassini-Vieira","year":"2015","journal-title":"Bioprotocol"},{"key":"10.1016\/j.colsurfb.2019.110749_bib0170","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1080\/02652040010000361","volume":"18","author":"Jenning","year":"2001","journal-title":"J. Microencapsul."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0175","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1208\/s12249-010-9563-0","volume":"12","author":"Das","year":"2011","journal-title":"AAPS PharmSciTech"},{"key":"10.1016\/j.colsurfb.2019.110749_bib0180","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.1002\/jps.21549","volume":"98","author":"Zhang","year":"2009","journal-title":"J. Pharm. Sci."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0185","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.colsurfb.2008.12.030","volume":"70","author":"Dragicevic-Curic","year":"2009","journal-title":"Colloids Surf. B Biointerfaces"},{"key":"10.1016\/j.colsurfb.2019.110749_bib0190","doi-asserted-by":"crossref","first-page":"E57","DOI":"10.3390\/pharmaceutics10020057","volume":"10","author":"Danaei","year":"2018","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.colsurfb.2019.110749_bib0195","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.2147\/IJN.S184912","volume":"14","author":"De Silva","year":"2019","journal-title":"Int. J. Nanomed."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0200","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1080\/10717544.2017.1284945","volume":"24","author":"Lu","year":"2017","journal-title":"Drug Deliv."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0205","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/0003-2697(83)90090-8","volume":"133","author":"Rockley","year":"1983","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0210","doi-asserted-by":"crossref","first-page":"3569","DOI":"10.1016\/S0032-3861(00)00713-8","volume":"42","author":"Brugnerottoa","year":"2001","journal-title":"Polymer"},{"key":"10.1016\/j.colsurfb.2019.110749_bib0215","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.3390\/md8051567","volume":"8","author":"Kumirska","year":"2010","journal-title":"Mar. Drugs"},{"key":"10.1016\/j.colsurfb.2019.110749_bib0220","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1211\/0022357044959","volume":"56","author":"Hu","year":"2004","journal-title":"J. Pharm. Pharmacol."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0225","doi-asserted-by":"crossref","DOI":"10.1154\/1.2903515","volume":"23","author":"Castro","year":"2008","journal-title":"Powder Diffr."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0230","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1007\/s10973-006-7684-1","volume":"87","author":"Lira","year":"2007","journal-title":"J. Therm. Anal. Calorim."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0235","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1080\/02652040701288519","volume":"24","author":"Castro","year":"2007","journal-title":"J. Microencapsul."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0240","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.ejps.2012.10.025","volume":"48","author":"Mussi","year":"2013","journal-title":"Eur. J. Pharm. Sci."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0245","first-page":"6011","volume":"7","author":"Carneiro","year":"2012","journal-title":"Int. J. Nanomed."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0250","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/S0378-5173(97)04890-4","volume":"151","author":"Westesen","year":"1997","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0255","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1248\/cpb.44.1039","volume":"44","author":"Panomsuk","year":"1996","journal-title":"Chem. Pharm. Bull."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0260","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.ijpharm.2016.01.045","volume":"500","author":"Khan","year":"2016","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0265","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1080\/026520499289176","volume":"16","author":"Sezer","year":"1999","journal-title":"J. Microencapsul."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0270","doi-asserted-by":"crossref","first-page":"465","DOI":"10.3109\/03639045.2010.522192","volume":"37","author":"Pattnaik","year":"2011","journal-title":"Drug Dev. Ind. Pharm."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0275","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.carbpol.2015.04.020","volume":"128","author":"Walke","year":"2015","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0280","first-page":"217","volume":"67","author":"Dash","year":"2010","journal-title":"Acta Pol. Pharm."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0285","first-page":"16","volume":"2","author":"Prajapati","year":"2012","journal-title":"J. Drug Deliv. Ther."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0290","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1002\/dmrr.2231","volume":"28","author":"Bharara","year":"2012","journal-title":"Diabetes Metab. Res. Rev."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0295","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1111\/j.1524-475X.2011.00673.x","volume":"19","author":"Schultz","year":"2011","journal-title":"Wound Repair Regen."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0300","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1007\/s00441-012-1410-z","volume":"351","author":"Martins","year":"2013","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0305","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2019.108615","volume":"112","author":"Patel","year":"2019","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0310","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1089\/ars.2017.7263","volume":"27","author":"Kunkemoeller","year":"2017","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0315","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1111\/j.1464-5491.2006.01773.x","volume":"23","author":"Blakytny","year":"2006","journal-title":"Diabet. Med."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0320","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1001\/archsurg.138.1.34","volume":"138","author":"Black","year":"2003","journal-title":"Arch. Surg."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0325","doi-asserted-by":"crossref","first-page":"2323","DOI":"10.1172\/JCI112243","volume":"76","author":"Grotendorst","year":"1985","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0330","doi-asserted-by":"crossref","first-page":"4157","DOI":"10.3390\/ijms20174157","volume":"20","author":"Crist\u00f3bal","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.colsurfb.2019.110749_bib0335","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1097\/PRS.0b013e3181eae781","volume":"126","author":"Larson","year":"2010","journal-title":"Plast. Reconstr. Surg."}],"container-title":["Colloids and Surfaces B: Biointerfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0927776519308938?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0927776519308938?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T10:45:18Z","timestamp":1760525118000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0927776519308938"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4]]},"references-count":67,"alternative-id":["S0927776519308938"],"URL":"https:\/\/doi.org\/10.1016\/j.colsurfb.2019.110749","relation":{},"ISSN":["0927-7765"],"issn-type":[{"value":"0927-7765","type":"print"}],"subject":[],"published":{"date-parts":[[2020,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Retinoic acid-loaded solid lipid nanoparticles surrounded by chitosan film support diabetic wound healing in in vivo study","name":"articletitle","label":"Article Title"},{"value":"Colloids and Surfaces B: Biointerfaces","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.colsurfb.2019.110749","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"110749"}}