{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T20:27:21Z","timestamp":1790022441279,"version":"4.0.1"},"reference-count":48,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100005667","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa e Inova\u00e7\u00e3o do Estado de Santa Catarina","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005667","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013360","name":"Universidade do Extremo Sul Catarinense","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013360","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Colloids and Surfaces B: Biointerfaces"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1016\/j.colsurfb.2020.111302","type":"journal-article","created":{"date-parts":[[2020,8,5]],"date-time":"2020-08-05T11:48:07Z","timestamp":1596628087000},"page":"111302","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":40,"special_numbering":"C","title":["Effects of gold nanoparticles administration through behavioral and oxidative parameters in animal model of Parkinson\u2019s disease"],"prefix":"10.1016","volume":"196","author":[{"given":"Emily","family":"da Silva C\u00f3rneo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gustavo","family":"de Bem Silveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rahisa","family":"Scussel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Eduarda Anast\u00e1cio Borges","family":"Correa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"da Silva Abel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel Paulino","family":"Luiz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2372-8945","authenticated-orcid":false,"given":"Paulo Emilio","family":"Feuser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4908-2257","authenticated-orcid":false,"given":"Paulo Cesar Lock","family":"Silveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1303-0490","authenticated-orcid":false,"given":"Ricardo Andrez","family":"Machado-de-\u00c1vila","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.colsurfb.2020.111302_bib0005","doi-asserted-by":"crossref","unstructured":"S. Gandhi, N.W.J.H.m.g. Wood, 14 (2005) 2749-2755.","DOI":"10.1093\/hmg\/ddi308"},{"key":"10.1016\/j.colsurfb.2020.111302_bib0010","doi-asserted-by":"crossref","unstructured":"L.M. De Lau, M.M.J.T.L.N. Breteler, 5 (2006) 525-535.","DOI":"10.1016\/S1474-4422(06)70471-9"},{"key":"10.1016\/j.colsurfb.2020.111302_bib0015","doi-asserted-by":"crossref","unstructured":"M.C. Shih, M.Q. Hoexter, L.A.F.d. Andrade, R.A.J.S.P.M.J. Bressan, 124 (2006) 168-175.","DOI":"10.1590\/S1516-31802006000300014"},{"key":"10.1016\/j.colsurfb.2020.111302_bib0020","doi-asserted-by":"crossref","unstructured":"R. Erro, F. Brigo, S. Tamburin, M. Zamboni, A. Antonini, M.J.J.o.n. Tinazzi, 265 (2018) 12-23.","DOI":"10.1007\/s00415-017-8639-0"},{"key":"10.1016\/j.colsurfb.2020.111302_bib0025","unstructured":"D. Jiang, Y.J.J.o.R. Peng, S. Transduction, (2020) 1-11."},{"key":"10.1016\/j.colsurfb.2020.111302_bib0030","doi-asserted-by":"crossref","unstructured":"R.N. Ferreira, A.S. de Miranda, N.P. Rocha, A.C. Simoes e Silva, A.L. Teixeira, E.R.J.C.M.C. da Silva Camargos, 25 (2018) 3682-3702.","DOI":"10.2174\/0929867325666180313101536"},{"key":"10.1016\/j.colsurfb.2020.111302_bib0035","doi-asserted-by":"crossref","unstructured":"R. Schwarting, J.J.P.i.n. Huston, 49 (1996) 215-266.","DOI":"10.1016\/S0301-0082(96)00015-9"},{"key":"10.1016\/j.colsurfb.2020.111302_bib0040","doi-asserted-by":"crossref","unstructured":"S. Palle, P.J.N.-S.s.a.o.p. Neerati, 391 (2018) 445-453.","DOI":"10.1007\/s00210-018-1474-8"},{"key":"10.1016\/j.colsurfb.2020.111302_bib0045","first-page":"115","volume":"223","author":"Wang","year":"2019","journal-title":"Pharmacology"},{"key":"10.1016\/j.colsurfb.2020.111302_bib0050","doi-asserted-by":"crossref","unstructured":"S.E. Starkstein, S. Brockman, B.D.J.C.o.i.p. Hayhow, 25 (2012) 468-472.","DOI":"10.1097\/YCO.0b013e3283577ed1"},{"key":"10.1016\/j.colsurfb.2020.111302_bib0055","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/j.msec.2014.08.045","volume":"44","author":"Silveira","year":"2014","journal-title":"Mater. Sci. Eng. C Mater. Biol. Appl."},{"key":"10.1016\/j.colsurfb.2020.111302_bib0060","doi-asserted-by":"crossref","unstructured":"X. Yang, M. Yang, B. Pang, M. Vara, Y.J.C.r. Xia, 115 (2015) 10410-10488.","DOI":"10.1021\/acs.chemrev.5b00193"},{"key":"10.1016\/j.colsurfb.2020.111302_bib0065","doi-asserted-by":"crossref","unstructured":"C. Tapeinos, M. Battaglini, G.J.J.o.C.R. Ciofani, 264 (2017) 306-332.","DOI":"10.1016\/j.jconrel.2017.08.033"},{"key":"10.1016\/j.colsurfb.2020.111302_bib0070","doi-asserted-by":"crossref","unstructured":"J. Turkevich, P.C. Stevenson, J.J.D.o.t.F.S. Hillier, 11 (1951) 55-75.","DOI":"10.1039\/df9511100055"},{"key":"10.1016\/j.colsurfb.2020.111302_bib0075","doi-asserted-by":"crossref","unstructured":"Y. Nagakura, M. Takahashi, T. Noto, T. Sekizawa, T. Oe, E. Yoshimi, K. Tamaki, Y.J.B.b.r. Shimizu, 226 (2012) 242-249.","DOI":"10.1016\/j.bbr.2011.09.023"},{"key":"10.1016\/j.colsurfb.2020.111302_bib0080","doi-asserted-by":"crossref","unstructured":"A.P. Muller, G.K. Ferreira, S. da Silva, R.T. Nesi, G. de Bem Silveira, C. Mendes, R.A. Pinho, M.M. da Silva Paula, P.C.L.J.M.S. Silveira, E. C, 77 (2017) 1145-1150.","DOI":"10.1016\/j.msec.2017.04.027"},{"key":"10.1016\/j.colsurfb.2020.111302_bib0085","first-page":"333","volume":"7","author":"Vianna","year":"2000","journal-title":"Memory"},{"key":"10.1016\/j.colsurfb.2020.111302_bib0090","doi-asserted-by":"crossref","unstructured":"M.F. Rossato, G. Trevisan, C.I.B. Walker, J.Z. Klafke, A.P. de Oliveira, J.G. Villarinho, R.B. Zanon, L.F.F. Royes, M.L. Athayde, M.V.J.B.p. Gomez, 81 (2011) 544-551.","DOI":"10.1016\/j.bcp.2010.11.004"},{"key":"10.1016\/j.colsurfb.2020.111302_bib0095","doi-asserted-by":"crossref","unstructured":"S. Shiozaki, S. Ichikawa, J. Nakamura, S. Kitamura, K. Yamada, Y.J.P. Kuwana, 147 (1999) 90-95.","DOI":"10.1007\/s002130051146"},{"key":"10.1016\/j.colsurfb.2020.111302_bib0100","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","volume":"193","author":"Lowry","year":"1951","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.colsurfb.2020.111302_bib0105","first-page":"612","volume":"27","author":"Wang","year":"1999","journal-title":"Medicine"},{"key":"10.1016\/j.colsurfb.2020.111302_bib0110","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/S0142-9612(03)00605-7","volume":"25","author":"Chae","year":"2004","journal-title":"Biomaterials"},{"key":"10.1016\/j.colsurfb.2020.111302_bib0115","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S0304-3940(01)01636-6","volume":"302","author":"Aksenov","year":"2001","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.colsurfb.2020.111302_bib0120","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/0076-6879(90)86141-H","volume":"186","author":"Levine","year":"1990","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.colsurfb.2020.111302_bib0125","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/j.jpba.2006.07.030","volume":"43","author":"Grotto","year":"2007","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.colsurfb.2020.111302_bib0130","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1002\/9780470110539.ch5","volume":"32","author":"Bannister","year":"1987","journal-title":"Methods Biochem. Anal."},{"key":"10.1016\/j.colsurfb.2020.111302_bib0135","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/0003-2697(76)90326-2","volume":"74","author":"Hissin","year":"1976","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.colsurfb.2020.111302_bib0140","doi-asserted-by":"crossref","unstructured":"V.S. Fernandes, J.R. Santos, A.H. Le\u00e3o, A.M. Medeiros, T.G. Melo, G.S. Iz\u00eddio, A. Cabral, R.A. Ribeiro, V.C. Ab\u00edlio, A.M.J.B.B.R. Ribeiro, 231 (2012) 154-163.","DOI":"10.1016\/j.bbr.2012.03.008"},{"key":"10.1016\/j.colsurfb.2020.111302_bib0145","doi-asserted-by":"crossref","unstructured":"K.R. Chaudhuri, D.G. Healy, A.H.J.T.L.N. Schapira, 5 (2006) 235-245.","DOI":"10.1016\/S1474-4422(06)70373-8"},{"key":"10.1016\/j.colsurfb.2020.111302_bib0150","doi-asserted-by":"crossref","unstructured":"K.-i.J.J.o.n. Fujimoto, 256 (2009) 299-305.","DOI":"10.1007\/s00415-009-5245-9"},{"key":"10.1016\/j.colsurfb.2020.111302_bib0155","first-page":"1123","volume":"14","author":"Hu","year":"2018","journal-title":"Biol. Med."},{"key":"10.1016\/j.colsurfb.2020.111302_bib0160","unstructured":"X. Chen, C. Guo, J.J.N.r.r. Kong, 7 (2012) 376."},{"key":"10.1016\/j.colsurfb.2020.111302_bib0165","doi-asserted-by":"crossref","unstructured":"H. Braak, K. Del Tredici, U. R\u00fcb, R.A. De Vos, E.N.J. Steur, E.J.N.o.a. Braak, 24 (2003) 197-211.","DOI":"10.1016\/S0197-4580(02)00065-9"},{"key":"10.1016\/j.colsurfb.2020.111302_bib0170","doi-asserted-by":"crossref","first-page":"2209","DOI":"10.1271\/bbb.100375","volume":"74","author":"Sul","year":"2010","journal-title":"Biosci. Biotechnol. Biochem."},{"key":"10.1016\/j.colsurfb.2020.111302_bib0175","doi-asserted-by":"crossref","unstructured":"G. Becker, A. M\u00fcller, S. Braune, T. B\u00fcttner, R. Benecke, W. Greulich, W. Klein, G. Mark, J. Rieke, R.J.J.o.n. Th\u00fcmler, 249 (2002) iii40-iii48.","DOI":"10.1007\/s00415-002-1309-9"},{"key":"10.1016\/j.colsurfb.2020.111302_bib0180","first-page":"109","volume":"27","author":"Ab\u0131\u0301lio","year":"2003","journal-title":"B. Psychiatry"},{"key":"10.1016\/j.colsurfb.2020.111302_bib0185","doi-asserted-by":"crossref","unstructured":"E. Koutsilieri, M. Lutz, C.J.J.o.N.T. Scheller, 120 (2013) 75-81.","DOI":"10.1007\/s00702-012-0842-7"},{"key":"10.1016\/j.colsurfb.2020.111302_bib0190","first-page":"1","volume":"Vol. 108","author":"Ortiz","year":"2017"},{"key":"10.1016\/j.colsurfb.2020.111302_bib0195","doi-asserted-by":"crossref","unstructured":"C.X. Zhang, S.J.J.C.o.i.c.b. Lippard, 7 (2003) 481-489.","DOI":"10.1016\/S1367-5931(03)00081-4"},{"key":"10.1016\/j.colsurfb.2020.111302_bib0200","doi-asserted-by":"crossref","unstructured":"M.P. Rigobello, G. Scutari, A. Folda, A.J.B.p. Bindoli, 67 (2004) 689-696.","DOI":"10.1016\/j.bcp.2003.09.038"},{"key":"10.1016\/j.colsurfb.2020.111302_bib0205","unstructured":"T. Guttuso Jr, K.L. Andrzejewski, D.G. Lichter, J.K.J.J.o.t.n.s. Andersen, (2019)."},{"key":"10.1016\/j.colsurfb.2020.111302_bib0210","doi-asserted-by":"crossref","unstructured":"T.-H. Wang, Z.-T. Feng, P. Wei, H. Li, Z.-J. Shi, L.-Y.J.J.o.m.n. Li, 35 (2008) 161-169.","DOI":"10.1007\/s12031-007-9032-8"},{"key":"10.1016\/j.colsurfb.2020.111302_bib0215","doi-asserted-by":"crossref","unstructured":"V. Silani, A. Pizzuti, A. Falini, G. Borsani, E. Rugarli, C. Melo, A. Sidoli, F. Villani, F. Baralle, G.J.E.n. Scarlato, 113 (1991) 166-170.","DOI":"10.1016\/0014-4886(91)90172-9"},{"key":"10.1016\/j.colsurfb.2020.111302_bib0220","doi-asserted-by":"crossref","unstructured":"S. Allen, S. MacGowan, J. Treanor, R. Feeney, G. Wilcock, D.J.N.l. Dawbarn, 131 (1991) 135-139.","DOI":"10.1016\/0304-3940(91)90354-V"},{"key":"10.1016\/j.colsurfb.2020.111302_bib0225","doi-asserted-by":"crossref","unstructured":"M. Murer, Q. Yan, R.J.P.i.n. Raisman-Vozari, 63 (2001) 71-124.","DOI":"10.1016\/S0301-0082(00)00014-9"},{"key":"10.1016\/j.colsurfb.2020.111302_bib0230","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1002\/pri.159","volume":"4","author":"Marks","year":"1999","journal-title":"Physiother. Res. Int."},{"key":"10.1016\/j.colsurfb.2020.111302_bib0235","doi-asserted-by":"crossref","unstructured":"A.E. Lang, S. Gill, N.K. Patel, A. Lozano, J.G. Nutt, R. Penn, D.J. Brooks, G. Hotton, E. Moro, P.J.A.o.n. Heywood, 59 (2006) 459-466.","DOI":"10.1002\/ana.20737"},{"key":"10.1016\/j.colsurfb.2020.111302_bib0240","doi-asserted-by":"crossref","unstructured":"R. Seyedebrahimi, S. Razavi, J.J.J.o.C.S. Varshosaz, 31 (2020) 99-108.","DOI":"10.1007\/s10876-019-01621-9"}],"container-title":["Colloids and Surfaces B: Biointerfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0927776520306585?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0927776520306585?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T10:52:02Z","timestamp":1760525522000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0927776520306585"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12]]},"references-count":48,"alternative-id":["S0927776520306585"],"URL":"https:\/\/doi.org\/10.1016\/j.colsurfb.2020.111302","relation":{},"ISSN":["0927-7765"],"issn-type":[{"value":"0927-7765","type":"print"}],"subject":[],"published":{"date-parts":[[2020,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of gold nanoparticles administration through behavioral and oxidative parameters in animal model of Parkinson\u2019s disease","name":"articletitle","label":"Article Title"},{"value":"Colloids and Surfaces B: Biointerfaces","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.colsurfb.2020.111302","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"111302"}}