{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T17:58:37Z","timestamp":1790099917920,"version":"4.0.1"},"reference-count":51,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001407","name":"Department of Biotechnology, Ministry of Science and Technology, India","doi-asserted-by":"publisher","award":["BT\/PR6462\/FNS\/20\/669\/2012"],"award-info":[{"award-number":["BT\/PR6462\/FNS\/20\/669\/2012"]}],"id":[{"id":"10.13039\/501100001407","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001407","name":"Department of Biotechnology, Ministry of Science and Technology, India","doi-asserted-by":"publisher","award":["BT\/HD\/35\/02\/07\/2009"],"award-info":[{"award-number":["BT\/HD\/35\/02\/07\/2009"]}],"id":[{"id":"10.13039\/501100001407","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001407","name":"Department of Biotechnology, Ministry of Science and Technology, India","doi-asserted-by":"publisher","award":["3\/1\/3\/ICMR\/VFS\/HRD-2016"],"award-info":[{"award-number":["3\/1\/3\/ICMR\/VFS\/HRD-2016"]}],"id":[{"id":"10.13039\/501100001407","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001409","name":"Department of Science and Technology","doi-asserted-by":"publisher","award":["SR\/S2\/JCB-12\/2006"],"award-info":[{"award-number":["SR\/S2\/JCB-12\/2006"]}],"id":[{"id":"10.13039\/501100001409","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001409","name":"Department of Science and Technology","doi-asserted-by":"publisher","award":["SR\/WOS-A\/LS-363\/2018"],"award-info":[{"award-number":["SR\/WOS-A\/LS-363\/2018"]}],"id":[{"id":"10.13039\/501100001409","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Colloids and Surfaces B: Biointerfaces"],"published-print":{"date-parts":[[2021,8]]},"DOI":"10.1016\/j.colsurfb.2021.111811","type":"journal-article","created":{"date-parts":[[2021,4,30]],"date-time":"2021-04-30T12:18:35Z","timestamp":1619785115000},"page":"111811","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":28,"special_numbering":"C","title":["The gold nanoparticle reduces Vibrio cholerae pathogenesis by inhibition of biofilm formation and disruption of the production and structure of cholera toxin"],"prefix":"10.1016","volume":"204","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1894-5099","authenticated-orcid":false,"given":"Tanaya","family":"Chatterjee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tultul","family":"Saha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paramita","family":"Sarkar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazi Mirajul","family":"Hoque","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barun K.","family":"Chatterjee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pinak","family":"Chakrabarti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.colsurfb.2021.111811_bib0005","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1128\/CMR.8.1.48","article-title":"Cholera","volume":"8","author":"Kaper","year":"1995","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0010","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1038\/nrmicro821","article-title":"Bacterial biofilms: from the natural environment to infectious diseases","volume":"2","author":"Hall-Stoodley","year":"2004","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0015","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1111\/j.1365-2958.2005.04797.x","article-title":"Identification of novel stage-specific genetic requirements through whole genome transcription profiling of Vibrio cholerae biofilm development","volume":"57","author":"Moorthy","year":"2005","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0020","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1146\/annurev.micro.57.030502.090720","article-title":"Bacterial biofilms: an emerging link to disease pathogenesis","volume":"57","author":"Parsek","year":"2003","journal-title":"Annu. Rev. Microbiol."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0025","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/S1534-5807(03)00295-8","article-title":"Quorum sensing-dependent biofilms enhance colonization in Vibrio cholerae","volume":"5","author":"Zhu","year":"2003","journal-title":"Dev. Cell"},{"key":"10.1016\/j.colsurfb.2021.111811_bib0030","doi-asserted-by":"crossref","first-page":"3560","DOI":"10.1128\/IAI.00048-10","article-title":"Growth in a biofilm induces a hyperinfectious phenotype in Vibrio cholerae","volume":"78","author":"Tamayo","year":"2010","journal-title":"Infect. Immun."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0035","doi-asserted-by":"crossref","first-page":"6674","DOI":"10.1128\/IAI.73.10.6674-6679.2005","article-title":"Hyperinfectivity of human-passaged Vibrio cholerae can be modeled by growth in the infant mouse","volume":"73","author":"Alam","year":"2005","journal-title":"Infect. Immun."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0040","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1038\/nature00778","article-title":"Host-induced epidemic spread of the cholera bacterium","volume":"417","author":"Merrell","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.colsurfb.2021.111811_bib0045","doi-asserted-by":"crossref","first-page":"6350","DOI":"10.1073\/pnas.0601277103","article-title":"Transmissibility of cholera: In vivo-formed biofilms and their relationship to infectivity and persistence in the environment","volume":"103","author":"Faruque","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0050","doi-asserted-by":"crossref","first-page":"1794","DOI":"10.1128\/IAI.06277-11","article-title":"The Vibrio cholerae Pst2 phosphate transport system is upregulated in biofilms and contributes to biofilm-induced hyperinfectivity","volume":"80","author":"Mudrak","year":"2012","journal-title":"Infect. Immun."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0055","doi-asserted-by":"crossref","first-page":"2757","DOI":"10.1099\/mic.0.040196-0","article-title":"Role of Vibrio polysaccharide (vps) genes in VPS production, biofilm formation and Vibrio cholera pathogenesis","volume":"156","author":"Fong","year":"2010","journal-title":"Microbiology"},{"key":"10.1016\/j.colsurfb.2021.111811_bib0060","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1038\/nrmicro2415","article-title":"The biofilm matrix","volume":"8","author":"Flemming","year":"2010","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0065","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1128\/JB.188.3.1049-1059.2006","article-title":"Identification and characterization of RbmA, a novel protein required for the development of rugose colony morphology and biofilm structure in Vibrio cholerae","volume":"188","author":"Fong","year":"2006","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0070","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1126\/science.1222981","article-title":"Molecular architecture and assembly principles of Vibrio cholerae biofilms","volume":"337","author":"Berk","year":"2012","journal-title":"Science"},{"key":"10.1016\/j.colsurfb.2021.111811_bib0075","doi-asserted-by":"crossref","first-page":"5542","DOI":"10.1128\/IAI.01094-07","article-title":"Regulatory networks controlling Vibrio cholera virulence gene expression","volume":"75","author":"Matson","year":"2007","journal-title":"Infect. Immun."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0080","doi-asserted-by":"crossref","first-page":"7991","DOI":"10.1073\/pnas.93.15.7991","article-title":"Differential expression of the ToxR regulon in classical and E1 Tor biotypes of Vibrio cholerae is due to biotype-specific control over toxT expression","volume":"93","author":"DiRita","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0085","doi-asserted-by":"crossref","first-page":"3228","DOI":"10.1128\/JB.182.11.3228-3238.2000","article-title":"Differential activation of the tcpPH promoter by AphB determines biotype specificity of virulence gene expression in Vibrio cholerae","volume":"182","author":"Kovacikova","year":"2000","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0090","doi-asserted-by":"crossref","first-page":"3010","DOI":"10.1128\/IAI.68.5.3010-3014.2000","article-title":"Classical and El Tor biotypes of Vibrio cholerae differ in timing of transcription of tcpPH during growth in inducing conditions","volume":"68","author":"Murley","year":"2000","journal-title":"Infect. Immun."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0095","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/S0966-842X(00)01913-2","article-title":"Mechanisms of biofilm resistance to antimicrobial agents","volume":"9","author":"Mah","year":"2001","journal-title":"Trends Microbiol."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0100","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1111\/j.1365-2958.2004.04000.x","article-title":"Genetic evidence that the Vibrio cholerae monolayer is a distinct stage in biofilm development","volume":"52","author":"Moorthy","year":"2004","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0105","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1038\/nrmicro3433","article-title":"Living in the matrix: assembly and control of Vibrio cholerae biofilms","volume":"13","author":"Teschle","year":"2015","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0110","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.tibtech.2009.12.004","article-title":"Functionalised gold naoparticles for controlling pathogenic bacteria","volume":"28","author":"Pissuwan","year":"2010","journal-title":"Trends Biotechnol."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0115","doi-asserted-by":"crossref","first-page":"2346","DOI":"10.1088\/0957-4484\/16\/10\/059","article-title":"The bactericidal effect of silver nanoparticles","volume":"16","author":"Morones","year":"2005","journal-title":"Nanotechnology"},{"key":"10.1016\/j.colsurfb.2021.111811_bib0120","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.bbagen.2014.10.022","article-title":"Antibacterial effect of silver nanoparticles and the modeling of bacterial growth kinetics using a modified Gompertz model","volume":"1850","author":"Chatterjee","year":"2015","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.colsurfb.2021.111811_bib0125","doi-asserted-by":"crossref","first-page":"18877","DOI":"10.1038\/srep18877","article-title":"Potent antibacterial nanoparticles against biofilm and intracellular bacteria","volume":"6","author":"Mu","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0130","doi-asserted-by":"crossref","first-page":"26667","DOI":"10.1038\/srep26667","article-title":"Inhibition of gold nanoparticles (AuNPs) on pathogenic biofilm formation and invasion to host cells","volume":"6","author":"Yu","year":"2016","journal-title":"Sci. Rep."},{"issue":"8","key":"10.1016\/j.colsurfb.2021.111811_bib0135","doi-asserted-by":"crossref","first-page":"7775","DOI":"10.1021\/acsnano.5b01696","article-title":"Nanoparticle-Stabilized capsules for the treatment of bacterial biofilms","volume":"9","author":"Duncan","year":"2015","journal-title":"ACS Nano"},{"key":"10.1016\/j.colsurfb.2021.111811_bib0140","doi-asserted-by":"crossref","DOI":"10.2217\/fvl-2015-0010","article-title":"Gold nanoparticles and their applications in biomedicine","volume":"11","author":"Versiani","year":"2016","journal-title":"Future Virol."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0145","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-017-09357-0","article-title":"Modelling of growth kinetics of Vibrio cholerae in presence of gold nanoparticles: effect of size and morphology","volume":"7","author":"Chatterjee","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0150","doi-asserted-by":"crossref","first-page":"18303","DOI":"10.1074\/jbc.M117.793240","article-title":"Zinc oxide nanoparticles provide anti-cholera activity by disrupting the interaction of cholera toxin with the human GM1 receptor","volume":"292","author":"Sarwar","year":"2017","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0155","doi-asserted-by":"crossref","first-page":"5043","DOI":"10.1128\/IAI.00508-07","article-title":"Prolonged colonization of mice by Vibrio cholerae El Tor O1 depends on accessory toxins","volume":"75","author":"Olivier","year":"2007","journal-title":"Infect. Immun."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0160","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1093\/ajcp\/60.2.234","article-title":"Staining of bacteria in tissue sections: a reliable Gram stain method","volume":"60","author":"Brown","year":"1973","journal-title":"Am. J. Clin. Pathol."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0165","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1093\/protein\/6.4.383","article-title":"Evaluation of secondary structure of proteins from UV circular-dichroism spectra using an unsupervised learning neural-network","volume":"6","author":"Andrade","year":"1993","journal-title":"Protein Eng."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0170","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1002\/path.1700660228","article-title":"An experimental study of the mechanism of action of Vibrio cholerae on the intestinal mucous membrane","volume":"66","author":"De","year":"1953","journal-title":"J. Pathol. Bacteriol."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0175","doi-asserted-by":"crossref","first-page":"20404","DOI":"10.1074\/jbc.M113.467860","article-title":"The Epac1 signaling pathway regulates Cl\u2212 secretion via modulation of apical KCNN4c channels in diarrhea","volume":"288","author":"Sheikh","year":"2013","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0180","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1128\/IAI.01356-09","article-title":"Vibrio cholerae phosphoenolpyruvate phosphotransferase system control of carbohydate transport, biofilm formation, and colonization of the germfree mouse intestine","volume":"78","author":"Houot","year":"2010","journal-title":"Infect. Immun."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0185","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1039\/B514191E","article-title":"Why gold nanoparticles are more precious than pretty gold: noble metal surface plasmon resonance and its enhancement of the radiative and nonradiative properties of nanocrystals of different shapes","volume":"35","author":"Eustis","year":"2006","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0190","doi-asserted-by":"crossref","first-page":"7241","DOI":"10.1016\/j.biomaterials.2011.05.091","article-title":"Effect of gold nanoparticle morphology on adsorbed protein structure and function","volume":"32","author":"Gagner","year":"2011","journal-title":"Biomaterials"},{"key":"10.1016\/j.colsurfb.2021.111811_bib0195","doi-asserted-by":"crossref","first-page":"207","DOI":"10.3390\/toxins11040207","article-title":"Cholera toxin encapsulated within several Vibrio cholerae O1 serotype inaba outer membrane vesicles lacks a functional B-subunit","volume":"11","author":"Rasti","year":"2019","journal-title":"Toxins"},{"key":"10.1016\/j.colsurfb.2021.111811_bib0200","doi-asserted-by":"crossref","DOI":"10.1111\/jphp.13344","article-title":"A comprehensive review of therapeutic approaches available for the treatment of cholera","author":"Sousa","year":"2020","journal-title":"J. Pharmacy Pharmacol."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0205","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0004330","article-title":"Vibrio cholerae biofilms and cholera pathogenesis","author":"Silva","year":"2016","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0210","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1016\/j.nano.2016.02.006","article-title":"The antimicrobial activity of ZnO nanoparticles against Vibrio cholerae: variation in response depends on biotype","volume":"12","author":"Sarwar","year":"2016","journal-title":"Nanomed. Nanotechnol. Biol. Med."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0215","doi-asserted-by":"crossref","DOI":"10.1021\/acsabm.0c01483","article-title":"Virstatin-conjugated gold nanoparticle with enhanced antimicrobial activity against the Vibrio cholerae El Tor biotype","author":"Jana","year":"2021","journal-title":"ACS Appl. Biol. Mater."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0220","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1021\/acsinfecdis.7b00170","article-title":"New perspectives in biofilm eradication","volume":"4","author":"Wolfmeier","year":"2018","journal-title":"ACS Infect. Dis."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0225","doi-asserted-by":"crossref","first-page":"S886","DOI":"10.1080\/21691401.2018.1518909","article-title":"Anti-biofilm effects of gold and silver nanoparticles synthesized by Rhodiola rosea rhizome extracts","volume":"46","author":"Singh","year":"2018","journal-title":"Artif. Cells Nanomed. Biotechnol."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0230","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1128\/JB.01180-09","article-title":"The El Tor biotype of Vibrio cholerae exhibits a growth advantage in the stationary phase in mixed cultures with the classical biotype","volume":"192","author":"Pradhan","year":"2010","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0235","doi-asserted-by":"crossref","first-page":"3633","DOI":"10.1128\/IAI.01750-05","article-title":"Differences in gene expression between the classical and El Tor biotypes of Vibrio cholerae O1","volume":"74","author":"Beyhan","year":"2006","journal-title":"Infect. Immun."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0240","doi-asserted-by":"crossref","first-page":"3277","DOI":"10.1128\/JB.00374-13","article-title":"Structural basis for biofilm formation via the Vibrio cholera matrix protein Rbma","volume":"195","author":"Giglio","year":"2013","journal-title":"J. Bact."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0245","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1038\/nchembio.2007.24","article-title":"Targeting virulence: a new paradigm for antimicrobial therapy","volume":"3","author":"Clatworthy","year":"2007","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0250","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1111\/lam.12456","article-title":"Inhibition of quorum-sensing-dependent virulence factors and biofilm formation of clinical and environmental Pseudomonas aeruginosa strains by ZnO nanoparticles","volume":"61","author":"Garc\u00eda-Lara","year":"2015","journal-title":"Lett. Appl. Microbiol."},{"key":"10.1016\/j.colsurfb.2021.111811_bib0255","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1016\/j.bbagen.2017.02.007","article-title":"Structure and function of Vibrio cholerae accessory cholera enterotoxin in presence of gold nanoparticles: dependency on morphology","volume":"1861","author":"Chatterjee","year":"2017","journal-title":"Biochim. Biophys. Acta"}],"container-title":["Colloids and Surfaces B: Biointerfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0927776521002551?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0927776521002551?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T16:11:30Z","timestamp":1778775090000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0927776521002551"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8]]},"references-count":51,"alternative-id":["S0927776521002551"],"URL":"https:\/\/doi.org\/10.1016\/j.colsurfb.2021.111811","relation":{},"ISSN":["0927-7765"],"issn-type":[{"value":"0927-7765","type":"print"}],"subject":[],"published":{"date-parts":[[2021,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The gold nanoparticle reduces Vibrio cholerae pathogenesis by inhibition of biofilm formation and disruption of the production and structure of cholera toxin","name":"articletitle","label":"Article Title"},{"value":"Colloids and Surfaces B: Biointerfaces","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.colsurfb.2021.111811","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"111811"}}