{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T05:51:05Z","timestamp":1778824265792,"version":"3.51.4"},"reference-count":48,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Colloids and Surfaces B: Biointerfaces"],"published-print":{"date-parts":[[2021,12]]},"DOI":"10.1016\/j.colsurfb.2021.112100","type":"journal-article","created":{"date-parts":[[2021,9,8]],"date-time":"2021-09-08T02:57:04Z","timestamp":1631069824000},"page":"112100","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Pheophorbide co-encapsulated with Cisplatin in folate-decorated PLGA nanoparticles to treat nasopharyngeal carcinoma: Combination of chemotherapy and photodynamic therapy"],"prefix":"10.1016","volume":"208","author":[{"given":"Benzhong","family":"Zhou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yunxia","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Longqiao","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xianping","family":"Shi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhitai","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feifeng","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zesheng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5975-0397","authenticated-orcid":false,"given":"Shengguo","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.colsurfb.2021.112100_bib0005","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/S0140-6736(19)30956-0","article-title":"Nasopharyngeal carcinoma","volume":"394","author":"Chen","year":"2019","journal-title":"Lancet"},{"key":"10.1016\/j.colsurfb.2021.112100_bib0010","doi-asserted-by":"crossref","first-page":"6344","DOI":"10.1002\/cam4.2501","article-title":"RIG-I promotes IFN\/JAK2 expression and the endoplasmic reticulum stress response to inhibit chemoradiation resistance in nasopharyngeal carcinoma","volume":"8","author":"Jing","year":"2019","journal-title":"Cancer Med."},{"key":"10.1016\/j.colsurfb.2021.112100_bib0015","first-page":"1299","article-title":"In vitro and in vivo effcacy of afatinib as a single agent or in combination with gemcitabine for the treatment of nasopharyngeal carcinoma","volume":"10","author":"Xue","year":"2016","journal-title":"Drug Des. Devel. Ther."},{"key":"10.1016\/j.colsurfb.2021.112100_bib0020","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1093\/jnci\/djq258","article-title":"Randomized trial of radiotherapy plus concurrent-adjuvant chemotherapy vs radiotherapy alone for regionally advanced nasopharyngeal carcinoma","volume":"102","author":"Lee","year":"2010","journal-title":"J. Natl. Cancer Inst. Monographs"},{"key":"10.1016\/j.colsurfb.2021.112100_bib0025","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1016\/j.oraloncology.2012.08.002","article-title":"Genomic determinants of normal tissue toxicity after radiotherapy for head and neck malignancy: a systematic review","volume":"48","author":"Ghazali","year":"2012","journal-title":"Oral Oncol."},{"key":"10.1016\/j.colsurfb.2021.112100_bib0030","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.phrs.2016.01.001","article-title":"Cisplatin resistance and opportunities for precision medicine","volume":"106","author":"Amable","year":"2016","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.colsurfb.2021.112100_bib0035","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1200\/JCO.1991.9.3.389","article-title":"Second-line platinum therapy in patients with ovarian cancer previously treated with Cisplatin","volume":"9","author":"Markman","year":"1991","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.colsurfb.2021.112100_bib0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.msec.2019.110201","article-title":"Folic acid-functionalized graphene oxide nanosheets via plasma etching as a platform to combine NIR anticancer phototherapy and targeted drug delivery","volume":"107","author":"Mauro","year":"2020","journal-title":"Mat. Sci. Eng. C."},{"key":"10.1016\/j.colsurfb.2021.112100_bib0045","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.jmst.2021.01.035","article-title":"Mitochondria-targeting multi-metallic ZnCuO nanoparticles and IR780 for efficient photodynamic and photothermal cancer treatments","volume":"86","author":"Ruttala","year":"2021","journal-title":"J. Mat. Sci. Tech."},{"key":"10.1016\/j.colsurfb.2021.112100_bib0050","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1038\/nrc1071","article-title":"Photodynamic therapy for cancer","volume":"3","author":"Dolmans","year":"2003","journal-title":"Nat. Rev. Canc."},{"key":"10.1016\/j.colsurfb.2021.112100_bib0055","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.1039\/c4pp00495g","article-title":"The role of photodynamic therapy in overcoming cancer drug resistance","volume":"14","author":"Spring","year":"2015","journal-title":"Photochem. Photobiol. Sci."},{"key":"10.1016\/j.colsurfb.2021.112100_bib0060","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1038\/nm.2890","article-title":"Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B","volume":"18","author":"Sun","year":"2012","journal-title":"Nat. Med."},{"key":"10.1016\/j.colsurfb.2021.112100_bib0065","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.addr.2009.01.004","article-title":"Design and development of dendrimer photosensitizer-incorporated polymeric micelles for enhanced photodynamic therapy","volume":"61","author":"Nishiyama","year":"2009","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.colsurfb.2021.112100_bib0070","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.addr.2010.03.011","article-title":"Tumor delivery of macromolecular drugs based on the EPR effect","volume":"63","author":"Torchilin","year":"2011","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.colsurfb.2021.112100_bib0075","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/j.biopha.2018.05.096","article-title":"Co-encapsulation of dual drug loaded in MLNPs: implication on sustained drug release and effectively inducing apoptosis in oral carcinoma cells","volume":"104","author":"Mehnath","year":"2018","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.colsurfb.2021.112100_bib0080","doi-asserted-by":"crossref","first-page":"17021","DOI":"10.1039\/C8NJ03251C","article-title":"Development of cholate conjugated hybrid polymeric micelles for FXR receptor mediated effective site-specific delivery of paclitaxel","volume":"42","author":"Mehnath","year":"2018","journal-title":"New J. Chem."},{"key":"10.1016\/j.colsurfb.2021.112100_bib0085","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/s12034-015-0946-4","article-title":"Size-controlled synthesis of biodegradable nanocarriers for targeted and controlled cancer drug delivery using salting out cation","volume":"39","author":"Balakrishanan","year":"2016","journal-title":"Bull. Mater. Sci."},{"key":"10.1016\/j.colsurfb.2021.112100_bib0090","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.jconrel.2017.04.043","article-title":"Smart chemistry-based nanosized drug delivery systems for systemic applications: a comprehensive review","volume":"258","author":"Ramasamy","year":"2017","journal-title":"J. Control. Release"},{"key":"10.1016\/j.colsurfb.2021.112100_bib0095","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.polymer.2017.11.020","article-title":"Thermoresponsive and pH triggered drug release of cholate functionalized poly(organophosphazene) \u2013 polylactic acid co-polymeric nanostructure integrated with ICG","volume":"133","author":"Mehnath","year":"2017","journal-title":"Polymer"},{"key":"10.1016\/j.colsurfb.2021.112100_bib0100","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.ijbiomac.2018.10.167","article-title":"Sericin-chitosan doped maleate gellan gum nanocomposites for effective cell damage in Mycobacterium tuberculosis","volume":"122","author":"Mehnath","year":"2019","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.colsurfb.2021.112100_bib0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbrc.2015.06.138","article-title":"Nanomedicine for the molecular diagnosis of cardiovascular pathologies","volume":"468","author":"Juenet","year":"2015","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.colsurfb.2021.112100_bib0110","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.3390\/pharmaceutics12121165","article-title":"Doxorubicin-loaded PLGA nanoparticles for Cancer therapy: molecular weight effect of PLGA in doxorubicin release for controlling immunogenic cell death","volume":"12","author":"Choi","year":"2020","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.colsurfb.2021.112100_bib0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2020.120478","article-title":"Multifunctional tumor-targeted PLGA nanoparticles delivering Pt(IV)\/siBIRC5 for US\/MRI imaging and overcoming ovarian cancer resistance","volume":"269","author":"Zhang","year":"2021","journal-title":"Biomaterials"},{"key":"10.1016\/j.colsurfb.2021.112100_bib0120","doi-asserted-by":"crossref","first-page":"4503","DOI":"10.2147\/DDDT.S275123","article-title":"Co-delivery anticancer drug nanoparticles for synergistic therapy against lung cancer cells","volume":"14","author":"Shen","year":"2020","journal-title":"Drug Des. Devel. Ther."},{"key":"10.1016\/j.colsurfb.2021.112100_bib0125","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1016\/j.msec.2016.09.052","article-title":"Superparamagnetic iron oxide nanoparticles conjugated with folic acid for dual target-specifc drug delivery and MRI in cancer theranostics","volume":"70","author":"Huang","year":"2017","journal-title":"Mater. Sci. Eng. C Mater. Biol. Appl."},{"key":"10.1016\/j.colsurfb.2021.112100_bib0130","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.msec.2018.03.015","article-title":"Folic acid-cysteamine modifed gold nanoparticle as a nanoprobe for targeted computed tomography imaging of cancer cells","volume":"89","author":"Khademi","year":"2018","journal-title":"Mater. Sci. Eng. C Mater. Biol. Appl."},{"key":"10.1016\/j.colsurfb.2021.112100_bib0135","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1080\/21691401.2018.1443116","article-title":"Selective apoptosis induction in cancer cells using folate-conjugated gold nanoparticles and controlling the laser irradiation conditions","volume":"46","author":"Zeinizade","year":"2018","journal-title":"Artif. Cells Nanomed. Biotechnol."},{"key":"10.1016\/j.colsurfb.2021.112100_bib0140","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1166\/jnd.2015.1074","article-title":"Noscapine loaded PLGA nanoparticles prepared using oil-in-water emulsion solvent evaporation method","volume":"3","author":"Yadav","year":"2016","journal-title":"J. Nanopharmaceutics Drug Del."},{"key":"10.1016\/j.colsurfb.2021.112100_bib0145","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.jsps.2013.12.002","article-title":"Nanoprecipitation is more efficient than emulsion solvent evaporation method to encapsulate cucurbitacin I in PLGA nanoparticles","volume":"22","author":"Alshamsan","year":"2014","journal-title":"Saudi Pharm. J."},{"key":"10.1016\/j.colsurfb.2021.112100_bib0150","series-title":"Emerging Technologies for Nanoparticle Manufacturing","article-title":"Salting Out and ionic gelation manufacturing techniques for nanoparticles","author":"Jitta","year":"2021"},{"key":"10.1016\/j.colsurfb.2021.112100_bib0155","doi-asserted-by":"crossref","first-page":"2228","DOI":"10.1002\/app.1326","article-title":"Preparation of poly(dl-lactide- co-glycolide) nanoparticles without surfactant","volume":"80","author":"Jeong","year":"2001","journal-title":"J. Appl. Polym. Sci."},{"key":"10.1016\/j.colsurfb.2021.112100_bib0160","doi-asserted-by":"crossref","first-page":"6118","DOI":"10.1021\/ie010267m","article-title":"Formation of perfluoro polyether coatings by the rapid expansion of Supercritical solutions (RESS) process Part1:experimental results","volume":"40","author":"Chernyak","year":"2001","journal-title":"Ind. Eng. Chem. Res."},{"key":"10.1016\/j.colsurfb.2021.112100_bib0165","doi-asserted-by":"crossref","first-page":"2779","DOI":"10.1007\/s11095-017-2257-5","article-title":"Purification of drug loaded PLGA nanoparticles prepared by emulsification solvent evaporation using stirred cell ultrafiltration technique","volume":"34","author":"Paswan","year":"2017","journal-title":"Pharm. Res."},{"key":"10.1016\/j.colsurfb.2021.112100_bib0170","doi-asserted-by":"crossref","first-page":"191","DOI":"10.3797\/scipharm.ISP.2015.10","article-title":"Curcumin-loaded PLA nanoparticles: formulation and physical evaluation","volume":"84","author":"Rachmawati","year":"2016","journal-title":"Sci. Pharm."},{"key":"10.1016\/j.colsurfb.2021.112100_bib0175","doi-asserted-by":"crossref","first-page":"403","DOI":"10.2478\/acph-2014-0032","article-title":"The influence of different formulations and process parameters during the preparation of drug-loaded PLGA microspheres evaluated by multivariate data analysis","volume":"64","author":"Vyslouzil","year":"2014","journal-title":"Acta Pharm."},{"key":"10.1016\/j.colsurfb.2021.112100_bib0180","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0378-5173(99)00422-6","article-title":"Influences of process parameters on nanoparticle preparation performed by a double emulsion pressure homogenization technique","volume":"196","author":"Lamprecht","year":"2000","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.colsurfb.2021.112100_bib0185","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S0168-3659(02)00127-X","article-title":"Residual polyvinyl alcohol associated with poly (d,l-lactide-co-glycolide) nanoparticles affects their physical properties and cellular uptake","volume":"82","author":"Sahoo","year":"2002","journal-title":"J. Control. Release"},{"key":"10.1016\/j.colsurfb.2021.112100_bib0190","doi-asserted-by":"crossref","first-page":"2285","DOI":"10.1016\/j.biomaterials.2005.11.008","article-title":"In vitro and in vivo studies on vitamin E TPGS-emulsified poly (D,L-lactic-co-glycolic acid) nanoparticles for paclitaxel formulation","volume":"27","author":"Win","year":"2006","journal-title":"Biomaterials"},{"key":"10.1016\/j.colsurfb.2021.112100_bib0195","first-page":"82","article-title":"Preparation of poly(lactide-coglycolide) microspheres and evaluation of pharmacokinetics and tissue distribution of BDMC-PLGA-MS in rats","volume":"13","author":"Li","year":"2018","journal-title":"Asian J. Pharm. Sci."},{"key":"10.1016\/j.colsurfb.2021.112100_bib0200","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1080\/10717544.2017.1422296","article-title":"Development of a novel morphological paclitaxel-loaded PLGA microspheres for effective cancer therapy: in vitro and in vivo evaluations","volume":"25","author":"Zhang","year":"2018","journal-title":"Drug Deliv."},{"key":"10.1016\/j.colsurfb.2021.112100_bib0205","doi-asserted-by":"crossref","DOI":"10.1002\/biot.201900408","article-title":"Smart nanocarriers for the delivery of nucleic acid\u2010based therapeutics: a comprehensive review","volume":"16","author":"Ramasamy","year":"2021","journal-title":"Biotechnol. J."},{"key":"10.1016\/j.colsurfb.2021.112100_bib0210","doi-asserted-by":"crossref","first-page":"5159","DOI":"10.1021\/acsbiomaterials.9b00982","article-title":"Polypeptide derivative of metformin with the combined advantage of a gene carrier and anticancer activity","volume":"5","author":"Ramasamy","year":"2019","journal-title":"ACS Biomater. Sci. Eng."},{"key":"10.1016\/j.colsurfb.2021.112100_bib0215","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.colsurfb.2016.11.002","article-title":"PEGylated polypeptide lipid nanocapsules to enhance the anticancer efficacy of erlotinib in non-small cell lung cancer","volume":"150","author":"Kim","year":"2017","journal-title":"Colloids Surf. B Biointerfaces"},{"key":"10.1016\/j.colsurfb.2021.112100_bib0220","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.jphotobiol.2014.08.021","article-title":"Synergistic effect of photodynamic therapy and cisplatin: a novel approach for cervical cancer","volume":"140","author":"De Freitas","year":"2014","journal-title":"J. Photochem. Photobiol. B"},{"key":"10.1016\/j.colsurfb.2021.112100_bib0225","doi-asserted-by":"crossref","first-page":"13332","DOI":"10.1021\/acsami.6b03881","article-title":"Co-delivery of cisplatin prodrug and chlorin e6 by mesoporous silica nanoparticles for chemo-photodynamic combination therapy to combat drug resistance","volume":"8","author":"Zhang","year":"2016","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.colsurfb.2021.112100_bib0230","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1021\/nn506963h","article-title":"Self-assembled core-shell nanoparticles for combined chemotherapy and photodynamic therapy of resistant head and neck cancers","volume":"9","author":"He","year":"2015","journal-title":"ACS Nano"},{"key":"10.1016\/j.colsurfb.2021.112100_bib0235","doi-asserted-by":"crossref","first-page":"317","DOI":"10.3390\/pharmaceutics12040317","article-title":"A novel treatment modality for malignant peripheral nerve sheath tumor using a dual-effect liposome to combine photodynamic therapy and chemotherapy","volume":"12","author":"Chen","year":"2020","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.colsurfb.2021.112100_bib0240","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1007\/s10103-012-1132-1","article-title":"Randomised controlled trial of ALA vs. Photofrin photodynamic therapy for highgrade dysplasia arising in Barrett\u2019s oesophagus","volume":"28","author":"Dunn","year":"2013","journal-title":"Laser Med. Sci."}],"container-title":["Colloids and Surfaces B: Biointerfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0927776521005440?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0927776521005440?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T11:08:18Z","timestamp":1760526498000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0927776521005440"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12]]},"references-count":48,"alternative-id":["S0927776521005440"],"URL":"https:\/\/doi.org\/10.1016\/j.colsurfb.2021.112100","relation":{},"ISSN":["0927-7765"],"issn-type":[{"value":"0927-7765","type":"print"}],"subject":[],"published":{"date-parts":[[2021,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Pheophorbide co-encapsulated with Cisplatin in folate-decorated PLGA nanoparticles to treat nasopharyngeal carcinoma: Combination of chemotherapy and photodynamic therapy","name":"articletitle","label":"Article Title"},{"value":"Colloids and Surfaces B: Biointerfaces","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.colsurfb.2021.112100","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"112100"}}