{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T11:04:21Z","timestamp":1778151861850,"version":"3.51.4"},"reference-count":26,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,3,29]],"date-time":"2024-03-29T00:00:00Z","timestamp":1711670400000},"content-version":"am","delay-in-days":302,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Colloids and Surfaces B: Biointerfaces"],"published-print":{"date-parts":[[2023,6]]},"DOI":"10.1016\/j.colsurfb.2023.113285","type":"journal-article","created":{"date-parts":[[2023,3,30]],"date-time":"2023-03-30T18:43:06Z","timestamp":1680201786000},"page":"113285","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Targeted paclitaxel prodrug nanoassemblies to improve therapeutic effects for liver cancer"],"prefix":"10.1016","volume":"226","author":[{"given":"Shasha","family":"Qin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiamin","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhiling","family":"Pan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Can","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bing-Feng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.colsurfb.2023.113285_bib1","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1093\/jjco\/hyx180","article-title":"Chemotherapy for hepatocellular carcinoma: current status and future perspectives","volume":"48","author":"Ikeda","year":"2018","journal-title":"Jpn J. Clin. Oncol."},{"key":"10.1016\/j.colsurfb.2023.113285_bib2","doi-asserted-by":"crossref","first-page":"2928507","DOI":"10.1155\/2019\/2928507","article-title":"Targeted delivery of paclitaxel in liver cancer using hyaluronic acid functionalized mesoporous hollow alumina nanoparticles","volume":"2019","author":"Gao","year":"2019","journal-title":"Biomed. Res Int"},{"key":"10.1016\/j.colsurfb.2023.113285_bib3","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1007\/s11596-020-2158-4","article-title":"Application of paclitaxel-loaded EGFR peptide-conjugated magnetic polymeric liposomes for liver cancer therapy","volume":"40","author":"Lin","year":"2020","journal-title":"Curr. Med Sci."},{"key":"10.1016\/j.colsurfb.2023.113285_bib4","doi-asserted-by":"crossref","first-page":"4422","DOI":"10.1021\/acsabm.1c00177","article-title":"CD147 monoclonal antibody targeted reduction-responsive camptothecin polyphosphoester nanomedicine for drug delivery in hepatocellular carcinoma cells","volume":"4","author":"Tian","year":"2021","journal-title":"ACS Appl. Bio Mater."},{"key":"10.1016\/j.colsurfb.2023.113285_bib5","doi-asserted-by":"crossref","first-page":"333","DOI":"10.4155\/tde-2019-0033","article-title":"The perspectives of using unimolecular micelles in nanodrug formulation","volume":"10","author":"Wu","year":"2019","journal-title":"Ther. Deliv."},{"key":"10.1016\/j.colsurfb.2023.113285_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.colsurfb.2022.112609","article-title":"Novel nanocarriers for silencing anti-phagocytosis CD47 marker in acute myeloid leukemia cells","volume":"217","author":"Hassan","year":"2022","journal-title":"Colloids Surf. B"},{"key":"10.1016\/j.colsurfb.2023.113285_bib7","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.jconrel.2018.08.030","article-title":"Exploiting the bioengineering versatility of lactobionic acid in targeted nanosystems and biomaterials","volume":"287","author":"Alonso","year":"2018","journal-title":"J. Control Release"},{"key":"10.1016\/j.colsurfb.2023.113285_bib8","doi-asserted-by":"crossref","first-page":"2547","DOI":"10.1016\/j.biomaterials.2012.12.038","article-title":"The targeted co-delivery of DNA and doxorubicin to tumor cells via multifunctional PEI-PEG based nanoparticles","volume":"34","author":"Liu","year":"2013","journal-title":"Biomaterials"},{"key":"10.1016\/j.colsurfb.2023.113285_bib9","doi-asserted-by":"crossref","first-page":"16288","DOI":"10.1073\/pnas.1210096109","article-title":"Engineering of blended nanoparticle platform for delivery of mitochondria-acting therapeutics","volume":"109","author":"Marrache","year":"2012","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.colsurfb.2023.113285_bib10","doi-asserted-by":"crossref","first-page":"5274","DOI":"10.3390\/molecules26175274","article-title":"zwitterionic polyurethane prodrug as drug delivery system for enhanced cancer therapy","volume":"26","author":"He","year":"2021","journal-title":"Molecules"},{"key":"10.1016\/j.colsurfb.2023.113285_bib11","doi-asserted-by":"crossref","first-page":"2806","DOI":"10.1021\/acs.bioconjchem.8b00421","article-title":"One-Pot synthesis of pH\/redox responsive polymeric prodrug and fabrication of shell cross-linked prodrug micelles for antitumor drug transportation","volume":"29","author":"Li","year":"2018","journal-title":"Bioconjug Chem."},{"key":"10.1016\/j.colsurfb.2023.113285_bib12","doi-asserted-by":"crossref","first-page":"42225","DOI":"10.1021\/acsami.7b14796","article-title":"Nanocolloidosomes with selective drug release for active tumor-targeted imaging-guided photothermal\/chemo combination therapy","volume":"9","author":"Hu","year":"2017","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.colsurfb.2023.113285_bib13","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/j.jconrel.2021.01.037","article-title":"A carrier-free anti-inflammatory platinum (II) self-delivered nanoprodrug for enhanced breast cancer therapy","volume":"331","author":"Xing","year":"2021","journal-title":"J. Control Release"},{"key":"10.1016\/j.colsurfb.2023.113285_bib14","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.actbio.2020.05.026","article-title":"Self-assembling prodrug nanotherapeutics for synergistic tumor targeted drug delivery","volume":"111","author":"Wang","year":"2020","journal-title":"Acta Biomater."},{"key":"10.1016\/j.colsurfb.2023.113285_bib15","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1080\/10717544.2017.1381201","article-title":"Self-delivering prodrug-nanoassemblies fabricated by disulfide bond bridged oleate prodrug of docetaxel for breast cancer therapy","volume":"24","author":"Zhang","year":"2017","journal-title":"Drug Deliv."},{"key":"10.1016\/j.colsurfb.2023.113285_bib16","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1007\/s12032-010-9621-1","article-title":"Integrin-targeted paclitaxel nanoliposomes for tumor therapy","volume":"28","author":"Meng","year":"2011","journal-title":"Med Oncol."},{"key":"10.1016\/j.colsurfb.2023.113285_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.colsurfb.2021.112162","article-title":"CD44-targeted, indocyanine green-paclitaxel-loaded human serum albumin nanoparticles for potential image-guided drug delivery","volume":"209","author":"Thangavel","year":"2022","journal-title":"Colloids Surf. B"},{"key":"10.1016\/j.colsurfb.2023.113285_bib18","doi-asserted-by":"crossref","first-page":"299","DOI":"10.2174\/156720108785915069","article-title":"Targeted delivery of macromolecular drugs: asialoglycoprotein receptor (ASGPR) expression by selected hepatoma cell lines used in antiviral drug development","volume":"5","author":"Li","year":"2008","journal-title":"Curr. Drug Deliv."},{"key":"10.1016\/j.colsurfb.2023.113285_bib19","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/j.ijbiomac.2022.02.176","article-title":"Novel derivatives of arabinogalactan, pullulan & lactobionic acid for targeting asialoglycoprotein receptor: biomolecular interaction, synthesis & evaluation","volume":"207","author":"Warrier","year":"2022","journal-title":"Int J. Biol. Macromol."},{"key":"10.1016\/j.colsurfb.2023.113285_bib20","doi-asserted-by":"crossref","DOI":"10.3390\/pharmaceutics11070327","article-title":"Chemistry routes for copolymer synthesis containing PEG for targeting, imaging, and drug delivery purposes","volume":"11","author":"Rahme","year":"2019","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.colsurfb.2023.113285_bib21","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1111\/cas.12737","article-title":"Novel nanosystem to enhance the antitumor activity of lapatinib in breast cancer treatment: therapeutic efficacy evaluation","volume":"106","author":"Huo","year":"2015","journal-title":"Cancer Sci."},{"key":"10.1016\/j.colsurfb.2023.113285_bib22","doi-asserted-by":"crossref","first-page":"2211","DOI":"10.1039\/C8NR06452K","article-title":"A novel \"mosaic-type\" nanoparticle for selective drug release targeting hypoxic cancer cells","volume":"11","author":"Wang","year":"2019","journal-title":"Nanoscale"},{"key":"10.1016\/j.colsurfb.2023.113285_bib23","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1080\/10837450.2017.1333516","article-title":"Polyester-based microdisc systems for sustained release of neuroprotective phosphine-borane complexes","volume":"23","author":"Janus","year":"2018","journal-title":"Pharm. Dev. Technol."},{"key":"10.1016\/j.colsurfb.2023.113285_bib24","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.ijpharm.2013.08.008","article-title":"Selective tissue distribution and long circulation endowed by paclitaxel loaded PEGylated poly (\u025b-caprolactone-co-l-lactide) micelles leading to improved anti-tumor effects and low systematic toxicity","volume":"456","author":"Wang","year":"2013","journal-title":"Int J. Pharm."},{"key":"10.1016\/j.colsurfb.2023.113285_bib25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/15685551.2020.1860481","article-title":"Preparation and properties of Pue-loaded HA-ADH-PS nanomicelles","volume":"24","author":"Wang","year":"2021","journal-title":"Des. Monomers Polym."},{"key":"10.1016\/j.colsurfb.2023.113285_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijpharm.2020.119870","article-title":"Multifunctional composite nanoparticles based on hyaluronic acid-paclitaxel conjugates for enhanced cancer therapy","volume":"589","author":"Luo","year":"2020","journal-title":"Int J. Pharm."}],"container-title":["Colloids and Surfaces B: Biointerfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0927776523001637?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0927776523001637?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T11:15:40Z","timestamp":1760526940000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0927776523001637"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6]]},"references-count":26,"alternative-id":["S0927776523001637"],"URL":"https:\/\/doi.org\/10.1016\/j.colsurfb.2023.113285","relation":{},"ISSN":["0927-7765"],"issn-type":[{"value":"0927-7765","type":"print"}],"subject":[],"published":{"date-parts":[[2023,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Targeted paclitaxel prodrug nanoassemblies to improve therapeutic effects for liver cancer","name":"articletitle","label":"Article Title"},{"value":"Colloids and Surfaces B: Biointerfaces","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.colsurfb.2023.113285","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"113285"}}