{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T02:55:51Z","timestamp":1791082551168,"version":"4.1.0"},"reference-count":34,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Colloids and Surfaces B: Biointerfaces"],"published-print":{"date-parts":[[2024,2]]},"DOI":"10.1016\/j.colsurfb.2023.113707","type":"journal-article","created":{"date-parts":[[2023,12,21]],"date-time":"2023-12-21T05:31:02Z","timestamp":1703136662000},"page":"113707","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"special_numbering":"C","title":["Photoresponsive metal-organic framework with combined photodynamic therapy and hypoxia-activated chemotherapy for the targeted treatment of rheumatoid arthritis"],"prefix":"10.1016","volume":"234","author":[{"given":"Shixin","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-5442-0075","authenticated-orcid":false,"given":"Miaomiao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingbo","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ge","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyue","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fengying","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenhua","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.colsurfb.2023.113707_bib1","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1016\/j.jconrel.2022.04.001","article-title":"Emerging nanotherapeutics alleviating rheumatoid arthritis by readjusting the seeds and soils","volume":"345","author":"Zhang","year":"2022","journal-title":"J. Control. Release"},{"key":"10.1016\/j.colsurfb.2023.113707_bib2","first-page":"317","article-title":"Instructive cartilage regeneration modalities with advanced therapeutic implantations under abnormal conditions","volume":"11","author":"Wang","year":"2022","journal-title":"Bioact. Mater."},{"key":"10.1016\/j.colsurfb.2023.113707_bib3","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.actbio.2021.03.062","article-title":"Immunoengineering the next generation of arthritis therapies","volume":"133","author":"Klimak","year":"2021","journal-title":"Acta Biomater."},{"issue":"7771","key":"10.1016\/j.colsurfb.2023.113707_bib4","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1038\/s41586-019-1471-1","article-title":"Locally renewing resident synovial macrophages provide a protective barrier for the joint","volume":"572","author":"Culemann","year":"2019","journal-title":"Nature"},{"issue":"4","key":"10.1016\/j.colsurfb.2023.113707_bib5","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1016\/j.apsb.2020.12.018","article-title":"Biological drug and drug delivery-mediated immunotherapy","volume":"11","author":"Xiao","year":"2021","journal-title":"Acta Pharm. Sin. B"},{"key":"10.1016\/j.colsurfb.2023.113707_bib6","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.jconrel.2022.01.029","article-title":"CaP-based anti-inflammatory HIF-1 alpha siRNA-encapsulating nanoparticle for rheumatoid arthritis therapy","volume":"343","author":"Liu","year":"2022","journal-title":"J. Control. Release"},{"issue":"4","key":"10.1016\/j.colsurfb.2023.113707_bib7","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1038\/s41584-021-00585-3","article-title":"The gut-joint axis in rheumatoid arthritis","volume":"17","author":"Zaiss","year":"2021","journal-title":"Nat. Rev. Rheumatol."},{"issue":"1","key":"10.1016\/j.colsurfb.2023.113707_bib8","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1021\/acsami.0c19468","article-title":"Treatment of Rheumatoid Arthritis by Serum Albumin Nanoparticles Coated with Mannose to Target Neutrophils","volume":"13","author":"Lyu","year":"2021","journal-title":"Acs Appl. Mater. Interfaces"},{"issue":"10","key":"10.1016\/j.colsurfb.2023.113707_bib9","doi-asserted-by":"crossref","first-page":"7728","DOI":"10.1021\/acs.nanolett.0c03279","article-title":"Inflammation-Targeted Celastrol Nanodrug Attenuates Collagen- Induced Arthritis through NF-kappa B and Notch1 Pathways","volume":"20","author":"An","year":"2020","journal-title":"Nano Lett."},{"key":"10.1016\/j.colsurfb.2023.113707_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2020.120390","article-title":"Targeted silver nanoparticles for rheumatoid arthritis therapy via macrophage apoptosis and Re-polarization","volume":"264","author":"Yang","year":"2021","journal-title":"Biomaterials"},{"issue":"5","key":"10.1016\/j.colsurfb.2023.113707_bib11","doi-asserted-by":"crossref","first-page":"4358","DOI":"10.1021\/acsnano.2c09127","article-title":"Redox Homeostasis Strategy for Inflammatory Macrophage Reprogramming in Rheumatoid Arthritis Based on Ceria Oxide Nanozyme-Complexed Biopolymeric Micelles","volume":"17","author":"Zhou","year":"2023","journal-title":"Acs Nano"},{"issue":"4","key":"10.1016\/j.colsurfb.2023.113707_bib12","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202205320","article-title":"Dual-Triggered Near-Infrared Persistent Luminescence Nanoprobe for Autofluorescence-Free Imaging-Guided Precise Therapy of Rheumatoid Arthritis","volume":"10","author":"Wang","year":"2023","journal-title":"Adv. Sci."},{"key":"10.1016\/j.colsurfb.2023.113707_bib13","first-page":"26","article-title":"Nanoengineered sonosensitive platelets for synergistically augmented sonodynamic tumor therapy by glutamine deprivation and cascading thrombosis","volume":"24","author":"Zhou","year":"2023","journal-title":"Bioact. Mater."},{"key":"10.1016\/j.colsurfb.2023.113707_bib14","unstructured":"Z.W. Chen, Y.J. Sun, J.W. Wang, X. Zhou, X.J. Kong, J.S. Meng, X.C. Zhang, Dual-Responsive Triple-Synergistic Fe-MOF for Tumor Theranostics, Acs Nano."},{"issue":"30","key":"10.1016\/j.colsurfb.2023.113707_bib15","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202211866","article-title":"Selective Methionine Pool Exhaustion Mediated by a Sequential Positioned MOF Nanotransformer for Intense Cancer Immunotherapy","volume":"35","author":"Wang","year":"2023","journal-title":"Adv. Mater."},{"issue":"27","key":"10.1016\/j.colsurfb.2023.113707_bib16","doi-asserted-by":"crossref","DOI":"10.1002\/smll.202202604","article-title":"Radicals Scavenging MOFs Enabling Targeting Delivery of siRNA for Rheumatoid Arthritis Therapy","volume":"18","author":"Guo","year":"2022","journal-title":"Small"},{"key":"10.1016\/j.colsurfb.2023.113707_bib17","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.jconrel.2020.10.069","article-title":"Rational design of metal-organic frameworks to deliver methotrexate for targeted rheumatoid arthritis therapy","volume":"330","author":"Guo","year":"2021","journal-title":"J. Control. Release"},{"issue":"1","key":"10.1016\/j.colsurfb.2023.113707_bib18","first-page":"29735","article-title":"Construction of a two-dimensional artificial antioxidase for nanocatalytic rheumatoid arthritis treatment","volume":"13","author":"Yang","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.colsurfb.2023.113707_bib19","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/j.jcis.2023.05.001","article-title":"A multifunctional metal-organic framework nanosystem disrupts redox homeostasis for synergistic therapy","volume":"645","author":"Sun","year":"2023","journal-title":"J. Colloid Interface Sci."},{"key":"10.1016\/j.colsurfb.2023.113707_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2022.140438","article-title":"Photoactivatable metal organic framework for synergistic ferroptosis and photodynamic therapy using 450 nm laser","volume":"454","author":"Chen","year":"2023","journal-title":"Chem. Eng. J."},{"issue":"51","key":"10.1016\/j.colsurfb.2023.113707_bib21","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.202209227","article-title":"An Intelligent Nanoplatform for Orthotopic Glioblastoma Therapy by Nonferrous Ferroptosis","volume":"32","author":"Cao","year":"2022","journal-title":"Adv. Funct. Mater."},{"issue":"22","key":"10.1016\/j.colsurfb.2023.113707_bib22","doi-asserted-by":"crossref","DOI":"10.1002\/smll.202300218","article-title":"Protein-Precoated Surface of Metal-Organic Framework Nanoparticles for Targeted Delivery","volume":"19","author":"Oh","year":"2023","journal-title":"Small"},{"issue":"15","key":"10.1016\/j.colsurfb.2023.113707_bib23","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202202280","article-title":"Mn3O4 Nanoshell Coated Metal-Organic Frameworks with Microenvironment-Driven O-2 Production and GSH Exhaustion Ability for Enhanced Chemodynamic and Photodynamic Cancer Therapies","volume":"12","author":"Li","year":"2023","journal-title":"Adv. Healthc. Mater."},{"key":"10.1016\/j.colsurfb.2023.113707_bib24","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.actbio.2021.10.032","article-title":"Biodegradable oxygen-producing manganese-chelated metal organic frameworks for tumor-targeted synergistic chemo\/photothermal\/photodynamic therapy","volume":"138","author":"Feng","year":"2022","journal-title":"Acta Biomater."},{"key":"10.1016\/j.colsurfb.2023.113707_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2020.128049","article-title":"Near-infrared light triggered photodynamic and nitric oxide synergistic antibacterial nanocomposite membrane","volume":"417","author":"Sun","year":"2021","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.colsurfb.2023.113707_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2023.141484","article-title":"Oxygen supplementation liposomes for rheumatoid arthritis treatment via synergistic phototherapy and repolarization of M1-to-M2 macrophages","volume":"459","author":"Zhang","year":"2023","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.colsurfb.2023.113707_bib27","article-title":"Photogenerated electrons from CeO2 via upconversion of excitons to conduction band enhanced photocatalysis for Photo-Therapy of Rheumatoid arthritis","volume":"446","author":"Li","year":"2022","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.colsurfb.2023.113707_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2021.121088","article-title":"A multifunctional nano-therapeutic platform based on octahedral yolk-shell Au NR@CuS: Photothermal\/photodynamic and targeted drug delivery tri-combined therapy for rheumatoid arthritis","volume":"277","author":"Huang","year":"2021","journal-title":"Biomaterials"},{"issue":"10","key":"10.1016\/j.colsurfb.2023.113707_bib29","doi-asserted-by":"crossref","first-page":"12319","DOI":"10.1021\/acsnano.2c12319","article-title":"Efficient NIR-II Type-I AIE Photosensitizer for Mitochondria-Targeted Photodynamic Therapy through Synergistic Apoptosis-Ferroptosis","volume":"17","author":"Zhuang","year":"2023","journal-title":"ACS nano"},{"issue":"19","key":"10.1016\/j.colsurfb.2023.113707_bib30","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202203019","article-title":"Drug Self-Delivery Nanocubes Enhance O2 -Economized Photodynamic-Immunotherapy of Triple-Negative Breast Cancer by Downregulating Wnt\/beta-catenin Signaling","volume":"12","author":"Feng","year":"2023","journal-title":"Adv. Healthc. Mater."},{"key":"10.1016\/j.colsurfb.2023.113707_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijpharm.2021.120947","article-title":"Folate receptor-targeting semiconducting polymer dots hybrid mesoporous silica nanoparticles against rheumatoid arthritis through synergistic photothermal therapy, photodynamic therapy, and chemotherapy","volume":"607","author":"Li","year":"2021","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.colsurfb.2023.113707_bib32","doi-asserted-by":"crossref","first-page":"6257","DOI":"10.2147\/IJN.S382252","article-title":"A Multifunctional Nano-Delivery System Against Rheumatoid Arthritis by Combined Phototherapy, Hypoxia-Activated Chemotherapy, and RNA Interference","volume":"17","author":"Li","year":"2022","journal-title":"Int. J. Nanomed."},{"key":"10.1016\/j.colsurfb.2023.113707_bib33","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202302508","article-title":"Augmenting Immunogenic Cell Death and Alleviating Myeloid-Derived Suppressor Cells by Sono-Activatable Semiconducting Polymer Nanopartners for Immunotherapy","author":"Ding","year":"2023","journal-title":"Adv. Mater."},{"key":"10.1016\/j.colsurfb.2023.113707_bib34","article-title":"A self-amplified necrotic targeting theranostic nanoparticle with deep tumor penetration for imaging-guided personalized chemo-photodynamic therapy","volume":"455","author":"Zhang","year":"2023","journal-title":"Chem. Eng. J."}],"container-title":["Colloids and Surfaces B: Biointerfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S092777652300601X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S092777652300601X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T11:30:40Z","timestamp":1760527840000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S092777652300601X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2]]},"references-count":34,"alternative-id":["S092777652300601X"],"URL":"https:\/\/doi.org\/10.1016\/j.colsurfb.2023.113707","relation":{},"ISSN":["0927-7765"],"issn-type":[{"value":"0927-7765","type":"print"}],"subject":[],"published":{"date-parts":[[2024,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Photoresponsive metal-organic framework with combined photodynamic therapy and hypoxia-activated chemotherapy for the targeted treatment of rheumatoid arthritis","name":"articletitle","label":"Article Title"},{"value":"Colloids and Surfaces B: Biointerfaces","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.colsurfb.2023.113707","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"113707"}}